Primary non-metastatic omental myofibrosarcoma in a horse
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352022000300514 |
Resumo: | ABSTRACT Myofibrosarcoma in horses is a rare malignant tumor composed predominantly by myofibroblasts. A 15-year-old horse was referred to the Veterinary Hospital of the Federal University of Parana for evaluation of colic signs. Initial physical examination showed icteric mucous membrane and laboratory analysis found anemia, increased serum activity of ALT, GGT, ALP, and bilirubin. In the exploratory laparotomy a highly vascularized abdominal mass in the left hypochondrium region of approximately 50cm x 45cm x 30cm, adhered to the surrounding structures was observed. Due to the size and adhesions to the omentum, the mass was considered surgically unresectable, and euthanasia was performed followed by necropsy. The immunohistochemical and morphological results indicate the diagnosis of myofibrosarcoma since the neoplastic cells immunoexpressed Vimentin, HHF35 and S100. To the authors’ knowledge, this is the first equine case of omental myofibrosarcoma described in the literature. |
id |
UFMG-8_cd6260d1dd826e118aa7f3cb59c47d36 |
---|---|
oai_identifier_str |
oai:scielo:S0102-09352022000300514 |
network_acronym_str |
UFMG-8 |
network_name_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository_id_str |
|
spelling |
Primary non-metastatic omental myofibrosarcoma in a horseimmunohistochemistrymyofibroblastmyofibroblastic sarcomaneoplasiaABSTRACT Myofibrosarcoma in horses is a rare malignant tumor composed predominantly by myofibroblasts. A 15-year-old horse was referred to the Veterinary Hospital of the Federal University of Parana for evaluation of colic signs. Initial physical examination showed icteric mucous membrane and laboratory analysis found anemia, increased serum activity of ALT, GGT, ALP, and bilirubin. In the exploratory laparotomy a highly vascularized abdominal mass in the left hypochondrium region of approximately 50cm x 45cm x 30cm, adhered to the surrounding structures was observed. Due to the size and adhesions to the omentum, the mass was considered surgically unresectable, and euthanasia was performed followed by necropsy. The immunohistochemical and morphological results indicate the diagnosis of myofibrosarcoma since the neoplastic cells immunoexpressed Vimentin, HHF35 and S100. To the authors’ knowledge, this is the first equine case of omental myofibrosarcoma described in the literature.Universidade Federal de Minas Gerais, Escola de Veterinária2022-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352022000300514Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.74 n.3 2022reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/1678-4162-12503info:eu-repo/semantics/openAccessCocco,M.Lorga,A.D.Ferreira,A.A.Ribeiro Filho,P.A.R.Teixeira,W.T.Castro,J.L.C.Souza,R.S.Dornbusch,P.T.eng2022-06-07T00:00:00Zoai:scielo:S0102-09352022000300514Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2022-06-07T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.none.fl_str_mv |
Primary non-metastatic omental myofibrosarcoma in a horse |
title |
Primary non-metastatic omental myofibrosarcoma in a horse |
spellingShingle |
Primary non-metastatic omental myofibrosarcoma in a horse Cocco,M. immunohistochemistry myofibroblast myofibroblastic sarcoma neoplasia |
title_short |
Primary non-metastatic omental myofibrosarcoma in a horse |
title_full |
Primary non-metastatic omental myofibrosarcoma in a horse |
title_fullStr |
Primary non-metastatic omental myofibrosarcoma in a horse |
title_full_unstemmed |
Primary non-metastatic omental myofibrosarcoma in a horse |
title_sort |
Primary non-metastatic omental myofibrosarcoma in a horse |
author |
Cocco,M. |
author_facet |
Cocco,M. Lorga,A.D. Ferreira,A.A. Ribeiro Filho,P.A.R. Teixeira,W.T. Castro,J.L.C. Souza,R.S. Dornbusch,P.T. |
author_role |
author |
author2 |
Lorga,A.D. Ferreira,A.A. Ribeiro Filho,P.A.R. Teixeira,W.T. Castro,J.L.C. Souza,R.S. Dornbusch,P.T. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Cocco,M. Lorga,A.D. Ferreira,A.A. Ribeiro Filho,P.A.R. Teixeira,W.T. Castro,J.L.C. Souza,R.S. Dornbusch,P.T. |
dc.subject.por.fl_str_mv |
immunohistochemistry myofibroblast myofibroblastic sarcoma neoplasia |
topic |
immunohistochemistry myofibroblast myofibroblastic sarcoma neoplasia |
description |
ABSTRACT Myofibrosarcoma in horses is a rare malignant tumor composed predominantly by myofibroblasts. A 15-year-old horse was referred to the Veterinary Hospital of the Federal University of Parana for evaluation of colic signs. Initial physical examination showed icteric mucous membrane and laboratory analysis found anemia, increased serum activity of ALT, GGT, ALP, and bilirubin. In the exploratory laparotomy a highly vascularized abdominal mass in the left hypochondrium region of approximately 50cm x 45cm x 30cm, adhered to the surrounding structures was observed. Due to the size and adhesions to the omentum, the mass was considered surgically unresectable, and euthanasia was performed followed by necropsy. The immunohistochemical and morphological results indicate the diagnosis of myofibrosarcoma since the neoplastic cells immunoexpressed Vimentin, HHF35 and S100. To the authors’ knowledge, this is the first equine case of omental myofibrosarcoma described in the literature. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352022000300514 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352022000300514 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1678-4162-12503 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
dc.source.none.fl_str_mv |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.74 n.3 2022 reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online) instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
collection |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository.name.fl_str_mv |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br |
_version_ |
1750220895932121088 |