Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015

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Autor(a) principal: Chandrashekhar t Sreeramareddy
Data de Publicação: 2017
Outros Autores: Vasiliki Stathopoulou, Nicholas Steel, Caitlyn Steiner, Sabine Steinke, Ellen Nolte, Carl Abelardo t Antonio, Mark Andrew Stokes, Saverio Stranges, Mark Strong, Konstantinos Stroumpoulis, Adrienne Chew, Mirriam Chibalabala, Chioma Ezinne Chibueze, Vesper Hichilombwe Chisumpa, Abdulaal a Chitheer, Rajiv Chowdhury, Hanne Christensen, Devasahayam Jesudas Christopher, Liliana g Ciobanu, Rafael Tabarés-seisdedos, Seok-jun Yoon, Massimo Cirillo, Semaw Ferede Abera, Megan s Coggeshall, Leslie Trumbull Cooper, Monica Cortinovis, John a Crump, Koustuv Dalal, Hadi Danawi, Lalit Dandona, Rakhi Dandona, Mustafa z Younis, Karen m Tabb, Paul i Dargan, Jose Das Neves, Biju Abraham, Gail Davey, Dragos v Davitoiu, Kairat Davletov, Diego de Leo, Liana c Del Gobbo, Borja Del Pozo-cruz, Chuanhua yu, Robert p Dellavalle, Getachew Redae Taffere, Kebede Deribe, Amare Deribew, Don c Des Jarlais, Girmatsion Fisseha Abreha, Subhojit Dey, Samath d Dharmaratne, Daniel Dicker, Eric l Ding, Zoubida Zaidi, Klara Dokova, e Ray Dorsey, Roberto Tchio Talongwa, Kerrie e Doyle, Manisha Dubey, Rebecca Ehrenkranz, Christian Lycke Ellingsen, Kelemework Adane, Iqbal Elyazar, Ahmadali Enayati, Maysaa el Sayed Zaki, Sergey Petrovich Ermakov, Babak Eshrati, Alireza Esteghamati, Musharaf Tarajia, Kara Estep, Thomas Fürst, Imad d a Faghmous, Fanuel Belayneh Bekele Fanuel, Emerito Jose Aquino Faraon, Ademola Lukman Adelekan, Sachin r Atre, Talha a Farid, Carla Sofia e sa Farinha, Andre Faro, Maryam s Farvid, Mohammad Tavakkoli, Farshad Farzadfar, Valery l Feigin, Andrea b Feigl, Seyed-mohammad Fereshtehnejad, Jefferson g Fernandes, Carlos Zambrana-torrelio, João c Fernandes, Ifedayo Morayo o Adetifa, Tesfaye Regassa Feyissa, Florian Fischer, Christina Fitzmaurice, Nuno Taveira, Thomas d Fleming, Nataliya Foigt, Kyle j Foreman, Mohammad h Forouzanfar, Tomas Zapata, Richard c Franklin, Joseph Frostad, Tsegaye Tewelde G/hiwot, Nancy Fullman, Ashkan Afshin, Emmanuela Gakidou, Stephanie Teeple, Ketevan Gambashidze, Amiran Gamkrelidze, Wayne Gao, Zerihun Menlkalew Zenebe, Alberto l Garcia-basteiro, Teshome Gebre, Amanuel Tesfay Gebremedhin, Mengistu Welday Gebremichael, Alemseged Aregay Gebru, Amha Admasie Gelaye, Arnav Agarwal, Teketo Kassaw Tegegne, Johanna m Geleijnse, Ricard Genova-maleras, Sanjay Zodpey, Katherine b Gibney, Ababi Zergaw Giref, Melkamu Dedefo Gishu, Giorgia Giussani, William w Godwin, Audra Gold, Ellen m Goldberg, Philimon n Gona, al Artaman, Sanjay Kumar Agarwal, Lela Sturua, Amador Goodridge, Sameer Vali Gopalani, Atsushi Goto, Nicholas Graetz, Felix Greaves, Max Griswold, Peter Imre Guban, Harish Chander Gugnani, Prakash c Gupta, Arash Tehrani-banihashemi, Leo Zoeckler, Rahul Gupta, Sunilkumar Agarwal, Rajeev Gupta, Tanush Gupta, Vipin Gupta, Tesfa Dejenie Habtewold, Nima Hafezi-nejad, Demewoz Haile, Alemayehu Desalegne Hailu, Gessessew Bugssa Hailu, Liesl Joanna Zuhlke, Tesfalidet Tekelab, Alex Hakuzimana, Randah Ribhi Hamadeh, Anurag Agrawal, Mitiku Teshome Hambisa, Samer Hamidi, Mouhanad Hammami, Graeme j Hankey, Yuantao Hao, Hilda l Harb, Christopher j l Murray, Habtamu Abera Hareri, Dejen Yemane Tekle, Josep Maria Haro, Mohammad Sadegh Hassanvand, Rasmus Havmoeller, Aliasghar Ahmad Kiadaliri, Roderick j Hay, Simon i Hay, Delia Hendrie, Ileana Beatriz Heredia-pi, Amanuel Alemu Abajobir, Hans w Hoek, Masako Horino, Girma Temam Shifa, Nobuyuki Horita, h Dean Hosgood, Aung Soe Htet, Guoqing hu, Alireza Ahmadi, Hsiang Huang, John j Huang, Leticia Avila-burgos, Bethany m Huntley, Chantal Huynh, Kim Moesgaard Iburg, Abdullah Sulieman Terkawi, Bogdan Vasile Ileanu, Kaire Innos, Asnake Ararsa Irenso, Nader Jahanmehr, Mihajlo b Jakovljevic, Kedir Yimam Ahmed, Euripide Frinel g Arthur Avokpaho, Peter James, Spencer Lewis James, Mehdi Javanbakht, Sudha p Jayaraman, Azeb Gebresilassie Tesema, Achala Upendra Jayatilleke, Panniyammakal Jeemon, Vivekanand Jha, Denny John, Catherine Johnson, Beatriz Paulina Ayala Quintanilla, Sarah c Johnson, Muktar Beshir Ahmed, Jost b Jonas, Knud Juel, Zubair Kabir, js Thakur, Yogeshwar Kalkonde, Ritul Kamal, Haidong Kan, Andre Karch, Ashish Awasthi, Corine Kakizi Karema, Seyed m Karimi, Amir Kasaeian, Rufus Olusola Akinyemi, Nicholas j Kassebaum, Anshul Kastor, Alan j Thomson, Srinivasa Vittal Katikireddi, Konstantin Kazanjan, Peter Njenga Keiyoro, Nebiyu Negussu Ayele, Laura Kemmer, Andrew Haddon Kemp, Andre Pascal Kengne, Amene Abebe Kerbo, Maia Kereselidze, Reed j d Sorensen, Tomi f Akinyemiju, Taavi Tillmann, Chandrasekharan Nair Kesavachandran, Yousef Saleh Khader, Peter Azzopardi, Ibrahim Khalil, Abdur Rahman Khan, Ejaz Ahmad Khan, Gulfaraz Khan, Young-ho Khang, Abdullah Tawfih Abdullah Khoja, Irma Khonelidze, Jagdish Khubchandani, Tenaw Yimer Tiruye, Nadia Akseer, Muawiyyah Babale Sufiyan, Getiye Dejenu Kibret, Daniel Kim, Pauline Kim, Yun Jin Kim, Ruth w Kimokoti, Yohannes Kinfu, Niranjan Kissoon, Miia Kivipelto, Yoshihiro Kokubo, Hamid Asayesh, Huda Omer ba Saleem, Anneli Kolk, Ziyad Al-aly, Dhaval Kolte, Jacek a Kopec, Soewarta Kosen, Parvaiz a Koul, ai Koyanagi, Michael Kravchenko, Sanjay Krishnaswami, Kristopher j Krohn, Till Bärnighausen, Ruoyan Tobe-gai, Barthelemy Kuate Defo, Burcu Kucuk Bicer, Khurshid Alam, Ernst j Kuipers, Veena s Kulkarni, g Anil Kumar, Fekede Asefa Kumsa, Michael Kutz, Hmwe h Kyu, Umar Bacha, Anton Carl Jonas Lager, Marcello Tonelli, Aparna Lal, Dharmesh Kumar Lal, Ratilal Lalloo, Noore Alam, Tea Lallukka, Qing Lan, Sinead m Langan, Van c Lansingh, Alaa Badawi, Heidi j Larson, Anders Larsson, Roman Topor-madry, Dennis Odai Laryea, Asma Abdul Latif, Alicia Elena Beatriz Lawrynowicz, Janet l Leasher, Sayed Saidul Alam, James Leigh, Mall Leinsalu, Kalkidan Hassen Abate, Cheru Tesema Leshargie, Janni Leung, Ricky Leung, Miguel Tortajada, Miriam Levi, Xiaofeng Liang, Stephen s Lim, Margaret Lind, Shai Linn, Zewdie Aderaw Alemu, Amitava Banerjee, Steven e Lipshultz, Patrick Liu, Yang Liu, Loon-tzian lo, Christopher Troeger, Giancarlo Logroscino, Alan d Lopez, Scott a Lorch, Paulo a Lotufo, Rafael Lozano, Aleksandra Barac, Raimundas Lunevicius, Kefyalew Addis Alene, Ronan a Lyons, Erlyn Rachelle King Macarayan, Mark t Mackay, Thomas Truelsen, Hassan Magdy Abd el Razek, Mohammed Magdy Abd el Razek, Mahdi Mahdavi, Azeem Majeed, Miguel a Barboza, Reza Malekzadeh, Deborah Carvalho Malta, Lorenzo g Mantovani, Lily Alexander, Tsegahun Manyazewal, Chabila c Mapoma, Abera Kenay Tura, Wagner Marcenes, Guy b Marks, Neal Marquez, Suzanne l Barker-collo, Jose Martinez-raga, Melvin Barrientos Marzan, João Massano, Manu Raj Mathur, Pallab k Maulik, Raghib Ali, Mohsen Mazidi, Uche s Uchendu, Colm Mcalinden, John j Mcgrath, Lope h Barrero, Claire Mcnellan, Peter a Meaney, Alem Mehari, Man Mohan Mehndiratta, Toni Meier, Alemayehu b Mekonnen, Kidanu Gebremariam Meles, Thomas Bollyky, Kingsley n Ukwaja, Syed Danish Ali, Rizwan Abdulkader Suliankatchi, Ziad a Memish, Melkamu Merid Mengesha, Desalegn Tadese Mengiste, Mubarek Abera Mengistie, Bereket Gebremichael Menota, George a Mensah, Seid Tiku Mereta, Atte Meretoja, Tuomo j Meretoja, Eduardo a Undurraga, Sanjay Basu, Haftay Berhane Mezgebe, Reza Alizadeh-navaei, Renata Micha, Anoushka Millear, Edward j Mills, Shawn Minnig, Mojde Mirarefin, Erkin m Mirrakhimov, Charles n Mock, Karzan Abdulmuhsin Mohammad, Bernhard t Baune, Reza Assadi, Shafiu Mohammed, Sanjay k Mohanty, Ala'a Alkerwi, Ali h Mokdad, Glen Liddell d Mola, Mariam Molokhia, Lorenzo Monasta, Marcella Montico, Maziar Moradi-lakeh, Kaleab Baye, Paula Moraga, Chigozie Jesse Uneke, Lidia Morawska, Rintaro Mori, Mark Moses, François Alla, Ulrich o Mueller, Srinivas Murthy, Kamarul Imran Musa, Jean b Nachega, Yibeltal Tebekaw Bayou, Chie Nagata, Gabriele Nagel, Olalekan a Uthman, Mohsen Naghavi, Aliya Naheed, Luigi Naldi, Vinay Nangia, Peter Allebeck, Bruno Ramos Nascimento, Ionut Negoi, Shahrzad Bazargan-hejazi, Sudan Prasad Neupane, Charles r Newton, Marie ng, Job f m Van Boven, Frida Namnyak Ngalesoni, Josephine Wanjiku Ngunjiri, Grant Nguyen, Dina Nur Anggraini Ningrum, Sandra Nolte, Christine Allen, Cristiana Abbafati, Marika Nomura, Ole f Norheim, bo Norrving, Jean Jacques n Noubiap, Rita Van Dingenen, Carla Makhlouf Obermeyer, Felix Akpojene Ogbo, In-hwan oh, Anselm Okoro, Olanrewaju Oladimeji, Neeraj Bedi, Andrew Toyin Olagunju, Rajaa Al-raddadi, Pedro r Olivares, Helen e Olsen, Bolajoko Olubukunola Olusanya, Santosh Varughese, Jacob Olusegun Olusanya, John Nelson Opio, Eyal Oren, Alberto Ortiz, Ettore Beghi, Richard h Osborne, Majdi Osman, Mayowa o Owolabi, Ubai Alsharif, Mahesh pa, Amanda w Pain, Tommi Vasankari, Smita Pakhale, Elizabeth Palomares Castillo, Adrian Pana, Yannick Béjot, Christina Papachristou, Mahboubeh Parsaeian, Tejas Patel, George c Patton, Deepak Paudel, Khalid a Altirkawi, Vinod k Paul, Narayanaswamy Venketasubramanian, Neil Pearce, David m Pereira, Aminu k Bello, Rogelio Perez-padilla, Fernando Perez-ruiz, Norberto Perico, Konrad Pesudovs, Max Petzold, Michael Robert Phillips, David m Pigott, Elena Alvarez Martin, Francesco s Violante, Julian David Pillay, Jiandong Sun, Christine Pinho, Suzanne Polinder, Constance d Pond, v Prakash, Manorama Purwar, Mostafa Qorbani, d Alex Quistberg, Amir Radfar, Anwar Rafay, Sergey k Vladimirov, Derrick a Bennett, Martin Mckee, Nelson Alvis-guzman, Kazem Rahimi, Vafa Rahimi-movaghar, Mahfuzar Rahman, Mohammad Hifz ur Rahman, Rajesh Kumar Rai, Usha Ram, Saleem m Rana, Zane Rankin, Isabela m Bensenor, Vasiliy Victorovich Vlassov, Paturi Vishnupriya Rao, Puja c Rao, Azmeraw t Amare, Salman Rawaf, Maria Albertina Santiago Rego, Marissa Reitsma, Giuseppe Remuzzi, Andre m n n Renzaho, Serge Resnikoff, Adugnaw Berhane, Satar Rezaei, Ayalew Astatkie, Mohammad Sadegh Rezai, Antonio Luiz Pinho Ribeiro, Hirbo Shore Roba, Erfan Amini, Mohammad Bagher Rokni, Luca Ronfani, Gholamreza Roshandel, Gregory a Roth, Eduardo Bernabé, Dietrich Rothenbacher, Nawal k Roy, Stein Emil Vollset, Perminder s Sachdev, Ben Benasco Sackey, Mohammad Yahya Saeedi, Saeid Safiri, Walid Ammar, Rajesh Sagar, Mohammad Ali Sahraian, Oscar Alberto Bernal, Muhammad Muhammad Saleh, Joshua a Salomon, Abdallah m Samy, Theo Vos, Juan Ramon Sanabria, Maria Dolores Sanchez-niño, Logan Sandar, Itamar s Santos, João Vasco Santos, Joshu Amo-adjei, Addisu Shunu Beyene, Milena m Santric Milicevic, Rodrigo Sarmiento-suarez, Benn Sartorius, Maheswar Satpathy, Joseph a Wagner, Miloje Savic, Monika Sawhney, Mete i Saylan, Ben Schöttker, Aletta e Schutte, Ryan Mbarber, David c Schwebel, Yaw Ampem Amoako, Soraya Seedat, Abdulbasit Musa Seid, Canaan Negash Seifu, Tolassa Wakayo, Sadaf g Sepanlou, Berrin Serdar, Edson e Servan-mori, Tesfaye Setegn, Kaja m Abbas, Katya Anne Shackelford, Amira Shaheen, Saeid Shahraz, Benjamin o Anderson, Masood Ali Shaikh, Marina Shakh-nazarova, Stephen g Waller, Mansour Shamsipour, Sheikh Mohammed Shariful Islam, Jayendra Sharma, Tariku Jibat Beyene, Rajesh Sharma, Jun She, Sara Sheikhbahaei, Jiabin Shen, Peilin Shi, Sofia Androudi, Mika Shigematsu, Judd l Walson, Min-jeong Shin, Rahman Shiri, Zulfiqar a Bhutta, Haitham Shoman, Mark g Shrime, Ephrem Lejore Sibamo Sibamo, Inga Dora Sigfusdottir, Diego Augusto Santos Silva, Dayane Gabriele Alves Silveira, Shireen Sindi, Hossein Ansari, Haidong Wang, Abhishek Singh, Patrick Sur, Jasvinder a Singh, om Prakash Singh, Prashant Kumar Singh, Virendra Singh, Abiy Hiruye Sinke, Aklilu Endalamaw Sinshaw, Vegard Skirbekk, Karen Sliwa, Alison Smith, Yuan-pang Wang, Sibhatu Biadgilign, Mustafa Geleto Ansha, Eugene Sobngwi, Samir Soneji, Joan b Soriano, Tatiane Cristina Moraes Sousa, Luciano a Sposato, David a Watkins, Elisabete Weiderpass, Tesfay Mehari Atey, Robert g Weintraub, Boris Bikbov, Chi-pang Wen, Andrea Werdecker, Joshua Wesana, Ronny Westerman, Harvey a Whiteford, James d Wilkinson, Charles Shey Wiysonge, Belete Getahun Woldeyes, Charles d a Wolfe, Suleman Atique, Sait Mentes Birlik, Sungho Won, Abdulhalik Workicho, Shimelash Bitew Workie, Mamo Wubshet, Denis Xavier, Gelin xu, Ajit Kumar Yadav, Mohsen Yaghoubi, Bereket Yakob, Lijing l Yan, Charles Birungi, Niguse Tadele Atnafu, Yuichiro Yano, Mehdi Yaseri, Hassen Hamid Yimam, Paul Yip, Naohiro Yonemoto, Stan Biryukov, Donal Bisanzio, Habtamu Mellie Bizuayehu, Dipan Bose, Foad Abd-allah, Michael Brainin, Soumya Swaminathan, Michael Brauer, Alexandra Brazinova, Nicholas j k Breitborde, Hermann Brenner, Zahid a Butt, Rosario Cárdenas, Lucero Cahuana-hurtado, Ismael Ricardo Campos-nonato, Josip Car, Abdishakur m Abdulle, Johan Ärnlöv, Juan Jesus Carrero, Daniel Casey, Valeria Caso, Carlos a Castañeda-orjuela, Jacqueline Castillo Rivas, Ferrán Catalá-lópez, Pedro Cecilio, Kelly Cercy, Fiona j Charlson, Alan z Chen, Bryan l Sykes, Ahmed Abdulahi Abdurahman
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1016/S0140-6736(17)30818-8
http://hdl.handle.net/1843/55521
https://orcid.org/0000-0001-5689-3870
Resumo: Background National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015.Methods We mapped the most widely used list of causes amenable to personal health care developed by Nolte and McKee to 32 GBD causes. We accounted for variations in cause of death certification and misclassifications through the extensive data standardisation processes and redistribution algorithms developed for GBD. To isolate the effects of personal health-care access and quality, we risk-standardised cause-specific mortality rates for each geography-year by removing the joint effects of local environmental and behavioural risks, and adding back the global levels of risk exposure as estimated for GBD 2015. We employed principal component analysis to create a single, interpretable summary measure–the Healthcare Quality and Access (HAQ) Index–on a scale of 0 to 100. The HAQ Index showed strong convergence validity as compared with other health-system indicators, including health expenditure per capita (r=0·88), an index of 11 universal health coverage interventions (r=0·83), and human resources for health per 1000 (r=0·77). We used free disposal hull analysis with bootstrapping to produce a frontier based on the relationship between the HAQ Index and the Socio-demographic Index (SDI), a measure of overall development consisting of income per capita, average years of education, and total fertility rates. This frontier allowed us to better quantify the maximum levels of personal health-care access and quality achieved across the development spectrum, and pinpoint geographies where gaps between observed and potential levels have narrowed or widened over time.Findings Between 1990 and 2015, nearly all countries and territories saw their HAQ Index values improve; nonetheless, the difference between the highest and lowest observed HAQ Index was larger in 2015 than in 1990, ranging from 28·6 to 94·6. Of 195 geographies, 167 had statistically significant increases in HAQ Index levels since 1990, with South Korea, Turkey, Peru, China, and the Maldives recording among the largest gains by 2015. Performance on the HAQ Index and individual causes showed distinct patterns by region and level of development, yet substantial heterogeneities emerged for several causes, including cancers in highest-SDI countries; chronic kidney disease, diabetes, diarrhoeal diseases, and lower respiratory infections among middle-SDI countries; and measles and tetanus among lowest-SDI countries. While the global HAQ Index average rose from 40·7 (95% uncertainty interval, 39·0–42·8) in 1990 to 53·7 (52·2–55·4) in 2015, far less progress occurred in narrowing the gap between observed HAQ Index values and maximum levels achieved; at the global level, the difference between the observed and frontier HAQ Index only decreased from 21·2 in 1990 to 20·1 in 2015. If every country and territory had achieved the highest observed HAQ Index by their corresponding level of SDI, the global average would have been 73·8 in 2015. Several countries, particularly in eastern and western sub-Saharan Africa, reached HAQ Index values similar to or beyond their development levels, whereas others, namely in southern sub-Saharan Africa, the Middle East, and south Asia, lagged behind what geographies of similar development attained between 1990 and 2015. Interpretation This novel extension of the GBD Study shows the untapped potential for personal health-care access and quality improvement across the development spectrum. Amid substantive advances in personal health care at the national level, heterogeneous patterns for individual causes in given countries or territories suggest that few places have consistently achieved optimal health-care access and quality across health-system functions and therapeutic areas. This is especially evident in middle-SDI countries, many of which have recently undergone or are currently experiencing epidemiological transitions. The HAQ Index, if paired with other measures of health-system haracteristics such as intervention coverage, could provide a robust avenue for tracking progress on universal health coverage and identifying local priorities for strengthening personal health-care quality and access throughout the world.
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spelling 2023-06-28T23:14:55Z2023-06-28T23:14:55Z2017-07-15390231266https://doi.org/10.1016/S0140-6736(17)30818-801406736http://hdl.handle.net/1843/55521https://orcid.org/0000-0001-5689-3870Background National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015.Methods We mapped the most widely used list of causes amenable to personal health care developed by Nolte and McKee to 32 GBD causes. We accounted for variations in cause of death certification and misclassifications through the extensive data standardisation processes and redistribution algorithms developed for GBD. To isolate the effects of personal health-care access and quality, we risk-standardised cause-specific mortality rates for each geography-year by removing the joint effects of local environmental and behavioural risks, and adding back the global levels of risk exposure as estimated for GBD 2015. We employed principal component analysis to create a single, interpretable summary measure–the Healthcare Quality and Access (HAQ) Index–on a scale of 0 to 100. The HAQ Index showed strong convergence validity as compared with other health-system indicators, including health expenditure per capita (r=0·88), an index of 11 universal health coverage interventions (r=0·83), and human resources for health per 1000 (r=0·77). We used free disposal hull analysis with bootstrapping to produce a frontier based on the relationship between the HAQ Index and the Socio-demographic Index (SDI), a measure of overall development consisting of income per capita, average years of education, and total fertility rates. This frontier allowed us to better quantify the maximum levels of personal health-care access and quality achieved across the development spectrum, and pinpoint geographies where gaps between observed and potential levels have narrowed or widened over time.Findings Between 1990 and 2015, nearly all countries and territories saw their HAQ Index values improve; nonetheless, the difference between the highest and lowest observed HAQ Index was larger in 2015 than in 1990, ranging from 28·6 to 94·6. Of 195 geographies, 167 had statistically significant increases in HAQ Index levels since 1990, with South Korea, Turkey, Peru, China, and the Maldives recording among the largest gains by 2015. Performance on the HAQ Index and individual causes showed distinct patterns by region and level of development, yet substantial heterogeneities emerged for several causes, including cancers in highest-SDI countries; chronic kidney disease, diabetes, diarrhoeal diseases, and lower respiratory infections among middle-SDI countries; and measles and tetanus among lowest-SDI countries. While the global HAQ Index average rose from 40·7 (95% uncertainty interval, 39·0–42·8) in 1990 to 53·7 (52·2–55·4) in 2015, far less progress occurred in narrowing the gap between observed HAQ Index values and maximum levels achieved; at the global level, the difference between the observed and frontier HAQ Index only decreased from 21·2 in 1990 to 20·1 in 2015. If every country and territory had achieved the highest observed HAQ Index by their corresponding level of SDI, the global average would have been 73·8 in 2015. Several countries, particularly in eastern and western sub-Saharan Africa, reached HAQ Index values similar to or beyond their development levels, whereas others, namely in southern sub-Saharan Africa, the Middle East, and south Asia, lagged behind what geographies of similar development attained between 1990 and 2015. Interpretation This novel extension of the GBD Study shows the untapped potential for personal health-care access and quality improvement across the development spectrum. Amid substantive advances in personal health care at the national level, heterogeneous patterns for individual causes in given countries or territories suggest that few places have consistently achieved optimal health-care access and quality across health-system functions and therapeutic areas. This is especially evident in middle-SDI countries, many of which have recently undergone or are currently experiencing epidemiological transitions. The HAQ Index, if paired with other measures of health-system haracteristics such as intervention coverage, could provide a robust avenue for tracking progress on universal health coverage and identifying local priorities for strengthening personal health-care quality and access throughout the world.engUniversidade Federal de Minas GeraisUFMGBrasilENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICAMED - DEPARTAMENTO DE CLÍNICA MÉDICAMED - DEPARTAMENTO DE PEDIATRIAThe LancetCarga Global da DoençaRegistros de MortalidadeRegistros de Saúde PessoalGlobal Burden of DiseaseMortalityPersonal HealthHealthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30818-8/fulltextChandrashekhar t 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dc.title.pt_BR.fl_str_mv Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
title Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
spellingShingle Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
Chandrashekhar t Sreeramareddy
Global Burden of Disease
Mortality
Personal Health
Carga Global da Doença
Registros de Mortalidade
Registros de Saúde Pessoal
title_short Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
title_full Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
title_fullStr Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
title_full_unstemmed Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
title_sort Healthcare access and quality index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the global burden of disease study 2015
author Chandrashekhar t Sreeramareddy
author_facet Chandrashekhar t Sreeramareddy
Vasiliki Stathopoulou
Nicholas Steel
Caitlyn Steiner
Sabine Steinke
Ellen Nolte
Carl Abelardo t Antonio
Mark Andrew Stokes
Saverio Stranges
Mark Strong
Konstantinos Stroumpoulis
Adrienne Chew
Mirriam Chibalabala
Chioma Ezinne Chibueze
Vesper Hichilombwe Chisumpa
Abdulaal a Chitheer
Rajiv Chowdhury
Hanne Christensen
Devasahayam Jesudas Christopher
Liliana g Ciobanu
Rafael Tabarés-seisdedos
Seok-jun Yoon
Massimo Cirillo
Semaw Ferede Abera
Megan s Coggeshall
Leslie Trumbull Cooper
Monica Cortinovis
John a Crump
Koustuv Dalal
Hadi Danawi
Lalit Dandona
Rakhi Dandona
Mustafa z Younis
Karen m Tabb
Paul i Dargan
Jose Das Neves
Biju Abraham
Gail Davey
Dragos v Davitoiu
Kairat Davletov
Diego de Leo
Liana c Del Gobbo
Borja Del Pozo-cruz
Chuanhua yu
Robert p Dellavalle
Getachew Redae Taffere
Kebede Deribe
Amare Deribew
Don c Des Jarlais
Girmatsion Fisseha Abreha
Subhojit Dey
Samath d Dharmaratne
Daniel Dicker
Eric l Ding
Zoubida Zaidi
Klara Dokova
e Ray Dorsey
Roberto Tchio Talongwa
Kerrie e Doyle
Manisha Dubey
Rebecca Ehrenkranz
Christian Lycke Ellingsen
Kelemework Adane
Iqbal Elyazar
Ahmadali Enayati
Maysaa el Sayed Zaki
Sergey Petrovich Ermakov
Babak Eshrati
Alireza Esteghamati
Musharaf Tarajia
Kara Estep
Thomas Fürst
Imad d a Faghmous
Fanuel Belayneh Bekele Fanuel
Emerito Jose Aquino Faraon
Ademola Lukman Adelekan
Sachin r Atre
Talha a Farid
Carla Sofia e sa Farinha
Andre Faro
Maryam s Farvid
Mohammad Tavakkoli
Farshad Farzadfar
Valery l Feigin
Andrea b Feigl
Seyed-mohammad Fereshtehnejad
Jefferson g Fernandes
Carlos Zambrana-torrelio
João c Fernandes
Ifedayo Morayo o Adetifa
Tesfaye Regassa Feyissa
Florian Fischer
Christina Fitzmaurice
Nuno Taveira
Thomas d Fleming
Nataliya Foigt
Kyle j Foreman
Mohammad h Forouzanfar
Tomas Zapata
Richard c Franklin
Joseph Frostad
Tsegaye Tewelde G/hiwot
Nancy Fullman
Ashkan Afshin
Emmanuela Gakidou
Stephanie Teeple
Ketevan Gambashidze
Amiran Gamkrelidze
Wayne Gao
Zerihun Menlkalew Zenebe
Alberto l Garcia-basteiro
Teshome Gebre
Amanuel Tesfay Gebremedhin
Mengistu Welday Gebremichael
Alemseged Aregay Gebru
Amha Admasie Gelaye
Arnav Agarwal
Teketo Kassaw Tegegne
Johanna m Geleijnse
Ricard Genova-maleras
Sanjay Zodpey
Katherine b Gibney
Ababi Zergaw Giref
Melkamu Dedefo Gishu
Giorgia Giussani
William w Godwin
Audra Gold
Ellen m Goldberg
Philimon n Gona
al Artaman
Sanjay Kumar Agarwal
Lela Sturua
Amador Goodridge
Sameer Vali Gopalani
Atsushi Goto
Nicholas Graetz
Felix Greaves
Max Griswold
Peter Imre Guban
Harish Chander Gugnani
Prakash c Gupta
Arash Tehrani-banihashemi
Leo Zoeckler
Rahul Gupta
Sunilkumar Agarwal
Rajeev Gupta
Tanush Gupta
Vipin Gupta
Tesfa Dejenie Habtewold
Nima Hafezi-nejad
Demewoz Haile
Alemayehu Desalegne Hailu
Gessessew Bugssa Hailu
Liesl Joanna Zuhlke
Tesfalidet Tekelab
Alex Hakuzimana
Randah Ribhi Hamadeh
Anurag Agrawal
Mitiku Teshome Hambisa
Samer Hamidi
Mouhanad Hammami
Graeme j Hankey
Yuantao Hao
Hilda l Harb
Christopher j l Murray
Habtamu Abera Hareri
Dejen Yemane Tekle
Josep Maria Haro
Mohammad Sadegh Hassanvand
Rasmus Havmoeller
Aliasghar Ahmad Kiadaliri
Roderick j Hay
Simon i Hay
Delia Hendrie
Ileana Beatriz Heredia-pi
Amanuel Alemu Abajobir
Hans w Hoek
Masako Horino
Girma Temam Shifa
Nobuyuki Horita
h Dean Hosgood
Aung Soe Htet
Guoqing hu
Alireza Ahmadi
Hsiang Huang
John j Huang
Leticia Avila-burgos
Bethany m Huntley
Chantal Huynh
Kim Moesgaard Iburg
Abdullah Sulieman Terkawi
Bogdan Vasile Ileanu
Kaire Innos
Asnake Ararsa Irenso
Nader Jahanmehr
Mihajlo b Jakovljevic
Kedir Yimam Ahmed
Euripide Frinel g Arthur Avokpaho
Peter James
Spencer Lewis James
Mehdi Javanbakht
Sudha p Jayaraman
Azeb Gebresilassie Tesema
Achala Upendra Jayatilleke
Panniyammakal Jeemon
Vivekanand Jha
Denny John
Catherine Johnson
Beatriz Paulina Ayala Quintanilla
Sarah c Johnson
Muktar Beshir Ahmed
Jost b Jonas
Knud Juel
Zubair Kabir
js Thakur
Yogeshwar Kalkonde
Ritul Kamal
Haidong Kan
Andre Karch
Ashish Awasthi
Corine Kakizi Karema
Seyed m Karimi
Amir Kasaeian
Rufus Olusola Akinyemi
Nicholas j Kassebaum
Anshul Kastor
Alan j Thomson
Srinivasa Vittal Katikireddi
Konstantin Kazanjan
Peter Njenga Keiyoro
Nebiyu Negussu Ayele
Laura Kemmer
Andrew Haddon Kemp
Andre Pascal Kengne
Amene Abebe Kerbo
Maia Kereselidze
Reed j d Sorensen
Tomi f Akinyemiju
Taavi Tillmann
Chandrasekharan Nair Kesavachandran
Yousef Saleh Khader
Peter Azzopardi
Ibrahim Khalil
Abdur Rahman Khan
Ejaz Ahmad Khan
Gulfaraz Khan
Young-ho Khang
Abdullah Tawfih Abdullah Khoja
Irma Khonelidze
Jagdish Khubchandani
Tenaw Yimer Tiruye
Nadia Akseer
Muawiyyah Babale Sufiyan
Getiye Dejenu Kibret
Daniel Kim
Pauline Kim
Yun Jin Kim
Ruth w Kimokoti
Yohannes Kinfu
Niranjan Kissoon
Miia Kivipelto
Yoshihiro Kokubo
Hamid Asayesh
Huda Omer ba Saleem
Anneli Kolk
Ziyad Al-aly
Dhaval Kolte
Jacek a Kopec
Soewarta Kosen
Parvaiz a Koul
ai Koyanagi
Michael Kravchenko
Sanjay Krishnaswami
Kristopher j Krohn
Till Bärnighausen
Ruoyan Tobe-gai
Barthelemy Kuate Defo
Burcu Kucuk Bicer
Khurshid Alam
Ernst j Kuipers
Veena s Kulkarni
g Anil Kumar
Fekede Asefa Kumsa
Michael Kutz
Hmwe h Kyu
Umar Bacha
Anton Carl Jonas Lager
Marcello Tonelli
Aparna Lal
Dharmesh Kumar Lal
Ratilal Lalloo
Noore Alam
Tea Lallukka
Qing Lan
Sinead m Langan
Van c Lansingh
Alaa Badawi
Heidi j Larson
Anders Larsson
Roman Topor-madry
Dennis Odai Laryea
Asma Abdul Latif
Alicia Elena Beatriz Lawrynowicz
Janet l Leasher
Sayed Saidul Alam
James Leigh
Mall Leinsalu
Kalkidan Hassen Abate
Cheru Tesema Leshargie
Janni Leung
Ricky Leung
Miguel Tortajada
Miriam Levi
Xiaofeng Liang
Stephen s Lim
Margaret Lind
Shai Linn
Zewdie Aderaw Alemu
Amitava Banerjee
Steven e Lipshultz
Patrick Liu
Yang Liu
Loon-tzian lo
Christopher Troeger
Giancarlo Logroscino
Alan d Lopez
Scott a Lorch
Paulo a Lotufo
Rafael Lozano
Aleksandra Barac
Raimundas Lunevicius
Kefyalew Addis Alene
Ronan a Lyons
Erlyn Rachelle King Macarayan
Mark t Mackay
Thomas Truelsen
Hassan Magdy Abd el Razek
Mohammed Magdy Abd el Razek
Mahdi Mahdavi
Azeem Majeed
Miguel a Barboza
Reza Malekzadeh
Deborah Carvalho Malta
Lorenzo g Mantovani
Lily Alexander
Tsegahun Manyazewal
Chabila c Mapoma
Abera Kenay Tura
Wagner Marcenes
Guy b Marks
Neal Marquez
Suzanne l Barker-collo
Jose Martinez-raga
Melvin Barrientos Marzan
João Massano
Manu Raj Mathur
Pallab k Maulik
Raghib Ali
Mohsen Mazidi
Uche s Uchendu
Colm Mcalinden
John j Mcgrath
Lope h Barrero
Claire Mcnellan
Peter a Meaney
Alem Mehari
Man Mohan Mehndiratta
Toni Meier
Alemayehu b Mekonnen
Kidanu Gebremariam Meles
Thomas Bollyky
Kingsley n Ukwaja
Syed Danish Ali
Rizwan Abdulkader Suliankatchi
Ziad a Memish
Melkamu Merid Mengesha
Desalegn Tadese Mengiste
Mubarek Abera Mengistie
Bereket Gebremichael Menota
George a Mensah
Seid Tiku Mereta
Atte Meretoja
Tuomo j Meretoja
Eduardo a Undurraga
Sanjay Basu
Haftay Berhane Mezgebe
Reza Alizadeh-navaei
Renata Micha
Anoushka Millear
Edward j Mills
Shawn Minnig
Mojde Mirarefin
Erkin m Mirrakhimov
Charles n Mock
Karzan Abdulmuhsin Mohammad
Bernhard t Baune
Reza Assadi
Shafiu Mohammed
Sanjay k Mohanty
Ala'a Alkerwi
Ali h Mokdad
Glen Liddell d Mola
Mariam Molokhia
Lorenzo Monasta
Marcella Montico
Maziar Moradi-lakeh
Kaleab Baye
Paula Moraga
Chigozie Jesse Uneke
Lidia Morawska
Rintaro Mori
Mark Moses
François Alla
Ulrich o Mueller
Srinivas Murthy
Kamarul Imran Musa
Jean b Nachega
Yibeltal Tebekaw Bayou
Chie Nagata
Gabriele Nagel
Olalekan a Uthman
Mohsen Naghavi
Aliya Naheed
Luigi Naldi
Vinay Nangia
Peter Allebeck
Bruno Ramos Nascimento
Ionut Negoi
Shahrzad Bazargan-hejazi
Sudan Prasad Neupane
Charles r Newton
Marie ng
Job f m Van Boven
Frida Namnyak Ngalesoni
Josephine Wanjiku Ngunjiri
Grant Nguyen
Dina Nur Anggraini Ningrum
Sandra Nolte
Christine Allen
Cristiana Abbafati
Marika Nomura
Ole f Norheim
bo Norrving
Jean Jacques n Noubiap
Rita Van Dingenen
Carla Makhlouf Obermeyer
Felix Akpojene Ogbo
In-hwan oh
Anselm Okoro
Olanrewaju Oladimeji
Neeraj Bedi
Andrew Toyin Olagunju
Rajaa Al-raddadi
Pedro r Olivares
Helen e Olsen
Bolajoko Olubukunola Olusanya
Santosh Varughese
Jacob Olusegun Olusanya
John Nelson Opio
Eyal Oren
Alberto Ortiz
Ettore Beghi
Richard h Osborne
Majdi Osman
Mayowa o Owolabi
Ubai Alsharif
Mahesh pa
Amanda w Pain
Tommi Vasankari
Smita Pakhale
Elizabeth Palomares Castillo
Adrian Pana
Yannick Béjot
Christina Papachristou
Mahboubeh Parsaeian
Tejas Patel
George c Patton
Deepak Paudel
Khalid a Altirkawi
Vinod k Paul
Narayanaswamy Venketasubramanian
Neil Pearce
David m Pereira
Aminu k Bello
Rogelio Perez-padilla
Fernando Perez-ruiz
Norberto Perico
Konrad Pesudovs
Max Petzold
Michael Robert Phillips
David m Pigott
Elena Alvarez Martin
Francesco s Violante
Julian David Pillay
Jiandong Sun
Christine Pinho
Suzanne Polinder
Constance d Pond
v Prakash
Manorama Purwar
Mostafa Qorbani
d Alex Quistberg
Amir Radfar
Anwar Rafay
Sergey k Vladimirov
Derrick a Bennett
Martin Mckee
Nelson Alvis-guzman
Kazem Rahimi
Vafa Rahimi-movaghar
Mahfuzar Rahman
Mohammad Hifz ur Rahman
Rajesh Kumar Rai
Usha Ram
Saleem m Rana
Zane Rankin
Isabela m Bensenor
Vasiliy Victorovich Vlassov
Paturi Vishnupriya Rao
Puja c Rao
Azmeraw t Amare
Salman Rawaf
Maria Albertina Santiago Rego
Marissa Reitsma
Giuseppe Remuzzi
Andre m n n Renzaho
Serge Resnikoff
Adugnaw Berhane
Satar Rezaei
Ayalew Astatkie
Mohammad Sadegh Rezai
Antonio Luiz Pinho Ribeiro
Hirbo Shore Roba
Erfan Amini
Mohammad Bagher Rokni
Luca Ronfani
Gholamreza Roshandel
Gregory a Roth
Eduardo Bernabé
Dietrich Rothenbacher
Nawal k Roy
Stein Emil Vollset
Perminder s Sachdev
Ben Benasco Sackey
Mohammad Yahya Saeedi
Saeid Safiri
Walid Ammar
Rajesh Sagar
Mohammad Ali Sahraian
Oscar Alberto Bernal
Muhammad Muhammad Saleh
Joshua a Salomon
Abdallah m Samy
Theo Vos
Juan Ramon Sanabria
Maria Dolores Sanchez-niño
Logan Sandar
Itamar s Santos
João Vasco Santos
Joshu Amo-adjei
Addisu Shunu Beyene
Milena m Santric Milicevic
Rodrigo Sarmiento-suarez
Benn Sartorius
Maheswar Satpathy
Joseph a Wagner
Miloje Savic
Monika Sawhney
Mete i Saylan
Ben Schöttker
Aletta e Schutte
Ryan Mbarber
David c Schwebel
Yaw Ampem Amoako
Soraya Seedat
Abdulbasit Musa Seid
Canaan Negash Seifu
Tolassa Wakayo
Sadaf g Sepanlou
Berrin Serdar
Edson e Servan-mori
Tesfaye Setegn
Kaja m Abbas
Katya Anne Shackelford
Amira Shaheen
Saeid Shahraz
Benjamin o Anderson
Masood Ali Shaikh
Marina Shakh-nazarova
Stephen g Waller
Mansour Shamsipour
Sheikh Mohammed Shariful Islam
Jayendra Sharma
Tariku Jibat Beyene
Rajesh Sharma
Jun She
Sara Sheikhbahaei
Jiabin Shen
Peilin Shi
Sofia Androudi
Mika Shigematsu
Judd l Walson
Min-jeong Shin
Rahman Shiri
Zulfiqar a Bhutta
Haitham Shoman
Mark g Shrime
Ephrem Lejore Sibamo Sibamo
Inga Dora Sigfusdottir
Diego Augusto Santos Silva
Dayane Gabriele Alves Silveira
Shireen Sindi
Hossein Ansari
Haidong Wang
Abhishek Singh
Patrick Sur
Jasvinder a Singh
om Prakash Singh
Prashant Kumar Singh
Virendra Singh
Abiy Hiruye Sinke
Aklilu Endalamaw Sinshaw
Vegard Skirbekk
Karen Sliwa
Alison Smith
Yuan-pang Wang
Sibhatu Biadgilign
Mustafa Geleto Ansha
Eugene Sobngwi
Samir Soneji
Joan b Soriano
Tatiane Cristina Moraes Sousa
Luciano a Sposato
David a Watkins
Elisabete Weiderpass
Tesfay Mehari Atey
Robert g Weintraub
Boris Bikbov
Chi-pang Wen
Andrea Werdecker
Joshua Wesana
Ronny Westerman
Harvey a Whiteford
James d Wilkinson
Charles Shey Wiysonge
Belete Getahun Woldeyes
Charles d a Wolfe
Suleman Atique
Sait Mentes Birlik
Sungho Won
Abdulhalik Workicho
Shimelash Bitew Workie
Mamo Wubshet
Denis Xavier
Gelin xu
Ajit Kumar Yadav
Mohsen Yaghoubi
Bereket Yakob
Lijing l Yan
Charles Birungi
Niguse Tadele Atnafu
Yuichiro Yano
Mehdi Yaseri
Hassen Hamid Yimam
Paul Yip
Naohiro Yonemoto
Stan Biryukov
Donal Bisanzio
Habtamu Mellie Bizuayehu
Dipan Bose
Foad Abd-allah
Michael Brainin
Soumya Swaminathan
Michael Brauer
Alexandra Brazinova
Nicholas j k Breitborde
Hermann Brenner
Zahid a Butt
Rosario Cárdenas
Lucero Cahuana-hurtado
Ismael Ricardo Campos-nonato
Josip Car
Abdishakur m Abdulle
Johan Ärnlöv
Juan Jesus Carrero
Daniel Casey
Valeria Caso
Carlos a Castañeda-orjuela
Jacqueline Castillo Rivas
Ferrán Catalá-lópez
Pedro Cecilio
Kelly Cercy
Fiona j Charlson
Alan z Chen
Bryan l Sykes
Ahmed Abdulahi Abdurahman
author_role author
author2 Vasiliki Stathopoulou
Nicholas Steel
Caitlyn Steiner
Sabine Steinke
Ellen Nolte
Carl Abelardo t Antonio
Mark Andrew Stokes
Saverio Stranges
Mark Strong
Konstantinos Stroumpoulis
Adrienne Chew
Mirriam Chibalabala
Chioma Ezinne Chibueze
Vesper Hichilombwe Chisumpa
Abdulaal a Chitheer
Rajiv Chowdhury
Hanne Christensen
Devasahayam Jesudas Christopher
Liliana g Ciobanu
Rafael Tabarés-seisdedos
Seok-jun Yoon
Massimo Cirillo
Semaw Ferede Abera
Megan s Coggeshall
Leslie Trumbull Cooper
Monica Cortinovis
John a Crump
Koustuv Dalal
Hadi Danawi
Lalit Dandona
Rakhi Dandona
Mustafa z Younis
Karen m Tabb
Paul i Dargan
Jose Das Neves
Biju Abraham
Gail Davey
Dragos v Davitoiu
Kairat Davletov
Diego de Leo
Liana c Del Gobbo
Borja Del Pozo-cruz
Chuanhua yu
Robert p Dellavalle
Getachew Redae Taffere
Kebede Deribe
Amare Deribew
Don c Des Jarlais
Girmatsion Fisseha Abreha
Subhojit Dey
Samath d Dharmaratne
Daniel Dicker
Eric l Ding
Zoubida Zaidi
Klara Dokova
e Ray Dorsey
Roberto Tchio Talongwa
Kerrie e Doyle
Manisha Dubey
Rebecca Ehrenkranz
Christian Lycke Ellingsen
Kelemework Adane
Iqbal Elyazar
Ahmadali Enayati
Maysaa el Sayed Zaki
Sergey Petrovich Ermakov
Babak Eshrati
Alireza Esteghamati
Musharaf Tarajia
Kara Estep
Thomas Fürst
Imad d a Faghmous
Fanuel Belayneh Bekele Fanuel
Emerito Jose Aquino Faraon
Ademola Lukman Adelekan
Sachin r Atre
Talha a Farid
Carla Sofia e sa Farinha
Andre Faro
Maryam s Farvid
Mohammad Tavakkoli
Farshad Farzadfar
Valery l Feigin
Andrea b Feigl
Seyed-mohammad Fereshtehnejad
Jefferson g Fernandes
Carlos Zambrana-torrelio
João c Fernandes
Ifedayo Morayo o Adetifa
Tesfaye Regassa Feyissa
Florian Fischer
Christina Fitzmaurice
Nuno Taveira
Thomas d Fleming
Nataliya Foigt
Kyle j Foreman
Mohammad h Forouzanfar
Tomas Zapata
Richard c Franklin
Joseph Frostad
Tsegaye Tewelde G/hiwot
Nancy Fullman
Ashkan Afshin
Emmanuela Gakidou
Stephanie Teeple
Ketevan Gambashidze
Amiran Gamkrelidze
Wayne Gao
Zerihun Menlkalew Zenebe
Alberto l Garcia-basteiro
Teshome Gebre
Amanuel Tesfay Gebremedhin
Mengistu Welday Gebremichael
Alemseged Aregay Gebru
Amha Admasie Gelaye
Arnav Agarwal
Teketo Kassaw Tegegne
Johanna m Geleijnse
Ricard Genova-maleras
Sanjay Zodpey
Katherine b Gibney
Ababi Zergaw Giref
Melkamu Dedefo Gishu
Giorgia Giussani
William w Godwin
Audra Gold
Ellen m Goldberg
Philimon n Gona
al Artaman
Sanjay Kumar Agarwal
Lela Sturua
Amador Goodridge
Sameer Vali Gopalani
Atsushi Goto
Nicholas Graetz
Felix Greaves
Max Griswold
Peter Imre Guban
Harish Chander Gugnani
Prakash c Gupta
Arash Tehrani-banihashemi
Leo Zoeckler
Rahul Gupta
Sunilkumar Agarwal
Rajeev Gupta
Tanush Gupta
Vipin Gupta
Tesfa Dejenie Habtewold
Nima Hafezi-nejad
Demewoz Haile
Alemayehu Desalegne Hailu
Gessessew Bugssa Hailu
Liesl Joanna Zuhlke
Tesfalidet Tekelab
Alex Hakuzimana
Randah Ribhi Hamadeh
Anurag Agrawal
Mitiku Teshome Hambisa
Samer Hamidi
Mouhanad Hammami
Graeme j Hankey
Yuantao Hao
Hilda l Harb
Christopher j l Murray
Habtamu Abera Hareri
Dejen Yemane Tekle
Josep Maria Haro
Mohammad Sadegh Hassanvand
Rasmus Havmoeller
Aliasghar Ahmad Kiadaliri
Roderick j Hay
Simon i Hay
Delia Hendrie
Ileana Beatriz Heredia-pi
Amanuel Alemu Abajobir
Hans w Hoek
Masako Horino
Girma Temam Shifa
Nobuyuki Horita
h Dean Hosgood
Aung Soe Htet
Guoqing hu
Alireza Ahmadi
Hsiang Huang
John j Huang
Leticia Avila-burgos
Bethany m Huntley
Chantal Huynh
Kim Moesgaard Iburg
Abdullah Sulieman Terkawi
Bogdan Vasile Ileanu
Kaire Innos
Asnake Ararsa Irenso
Nader Jahanmehr
Mihajlo b Jakovljevic
Kedir Yimam Ahmed
Euripide Frinel g Arthur Avokpaho
Peter James
Spencer Lewis James
Mehdi Javanbakht
Sudha p Jayaraman
Azeb Gebresilassie Tesema
Achala Upendra Jayatilleke
Panniyammakal Jeemon
Vivekanand Jha
Denny John
Catherine Johnson
Beatriz Paulina Ayala Quintanilla
Sarah c Johnson
Muktar Beshir Ahmed
Jost b Jonas
Knud Juel
Zubair Kabir
js Thakur
Yogeshwar Kalkonde
Ritul Kamal
Haidong Kan
Andre Karch
Ashish Awasthi
Corine Kakizi Karema
Seyed m Karimi
Amir Kasaeian
Rufus Olusola Akinyemi
Nicholas j Kassebaum
Anshul Kastor
Alan j Thomson
Srinivasa Vittal Katikireddi
Konstantin Kazanjan
Peter Njenga Keiyoro
Nebiyu Negussu Ayele
Laura Kemmer
Andrew Haddon Kemp
Andre Pascal Kengne
Amene Abebe Kerbo
Maia Kereselidze
Reed j d Sorensen
Tomi f Akinyemiju
Taavi Tillmann
Chandrasekharan Nair Kesavachandran
Yousef Saleh Khader
Peter Azzopardi
Ibrahim Khalil
Abdur Rahman Khan
Ejaz Ahmad Khan
Gulfaraz Khan
Young-ho Khang
Abdullah Tawfih Abdullah Khoja
Irma Khonelidze
Jagdish Khubchandani
Tenaw Yimer Tiruye
Nadia Akseer
Muawiyyah Babale Sufiyan
Getiye Dejenu Kibret
Daniel Kim
Pauline Kim
Yun Jin Kim
Ruth w Kimokoti
Yohannes Kinfu
Niranjan Kissoon
Miia Kivipelto
Yoshihiro Kokubo
Hamid Asayesh
Huda Omer ba Saleem
Anneli Kolk
Ziyad Al-aly
Dhaval Kolte
Jacek a Kopec
Soewarta Kosen
Parvaiz a Koul
ai Koyanagi
Michael Kravchenko
Sanjay Krishnaswami
Kristopher j Krohn
Till Bärnighausen
Ruoyan Tobe-gai
Barthelemy Kuate Defo
Burcu Kucuk Bicer
Khurshid Alam
Ernst j Kuipers
Veena s Kulkarni
g Anil Kumar
Fekede Asefa Kumsa
Michael Kutz
Hmwe h Kyu
Umar Bacha
Anton Carl Jonas Lager
Marcello Tonelli
Aparna Lal
Dharmesh Kumar Lal
Ratilal Lalloo
Noore Alam
Tea Lallukka
Qing Lan
Sinead m Langan
Van c Lansingh
Alaa Badawi
Heidi j Larson
Anders Larsson
Roman Topor-madry
Dennis Odai Laryea
Asma Abdul Latif
Alicia Elena Beatriz Lawrynowicz
Janet l Leasher
Sayed Saidul Alam
James Leigh
Mall Leinsalu
Kalkidan Hassen Abate
Cheru Tesema Leshargie
Janni Leung
Ricky Leung
Miguel Tortajada
Miriam Levi
Xiaofeng Liang
Stephen s Lim
Margaret Lind
Shai Linn
Zewdie Aderaw Alemu
Amitava Banerjee
Steven e Lipshultz
Patrick Liu
Yang Liu
Loon-tzian lo
Christopher Troeger
Giancarlo Logroscino
Alan d Lopez
Scott a Lorch
Paulo a Lotufo
Rafael Lozano
Aleksandra Barac
Raimundas Lunevicius
Kefyalew Addis Alene
Ronan a Lyons
Erlyn Rachelle King Macarayan
Mark t Mackay
Thomas Truelsen
Hassan Magdy Abd el Razek
Mohammed Magdy Abd el Razek
Mahdi Mahdavi
Azeem Majeed
Miguel a Barboza
Reza Malekzadeh
Deborah Carvalho Malta
Lorenzo g Mantovani
Lily Alexander
Tsegahun Manyazewal
Chabila c Mapoma
Abera Kenay Tura
Wagner Marcenes
Guy b Marks
Neal Marquez
Suzanne l Barker-collo
Jose Martinez-raga
Melvin Barrientos Marzan
João Massano
Manu Raj Mathur
Pallab k Maulik
Raghib Ali
Mohsen Mazidi
Uche s Uchendu
Colm Mcalinden
John j Mcgrath
Lope h Barrero
Claire Mcnellan
Peter a Meaney
Alem Mehari
Man Mohan Mehndiratta
Toni Meier
Alemayehu b Mekonnen
Kidanu Gebremariam Meles
Thomas Bollyky
Kingsley n Ukwaja
Syed Danish Ali
Rizwan Abdulkader Suliankatchi
Ziad a Memish
Melkamu Merid Mengesha
Desalegn Tadese Mengiste
Mubarek Abera Mengistie
Bereket Gebremichael Menota
George a Mensah
Seid Tiku Mereta
Atte Meretoja
Tuomo j Meretoja
Eduardo a Undurraga
Sanjay Basu
Haftay Berhane Mezgebe
Reza Alizadeh-navaei
Renata Micha
Anoushka Millear
Edward j Mills
Shawn Minnig
Mojde Mirarefin
Erkin m Mirrakhimov
Charles n Mock
Karzan Abdulmuhsin Mohammad
Bernhard t Baune
Reza Assadi
Shafiu Mohammed
Sanjay k Mohanty
Ala'a Alkerwi
Ali h Mokdad
Glen Liddell d Mola
Mariam Molokhia
Lorenzo Monasta
Marcella Montico
Maziar Moradi-lakeh
Kaleab Baye
Paula Moraga
Chigozie Jesse Uneke
Lidia Morawska
Rintaro Mori
Mark Moses
François Alla
Ulrich o Mueller
Srinivas Murthy
Kamarul Imran Musa
Jean b Nachega
Yibeltal Tebekaw Bayou
Chie Nagata
Gabriele Nagel
Olalekan a Uthman
Mohsen Naghavi
Aliya Naheed
Luigi Naldi
Vinay Nangia
Peter Allebeck
Bruno Ramos Nascimento
Ionut Negoi
Shahrzad Bazargan-hejazi
Sudan Prasad Neupane
Charles r Newton
Marie ng
Job f m Van Boven
Frida Namnyak Ngalesoni
Josephine Wanjiku Ngunjiri
Grant Nguyen
Dina Nur Anggraini Ningrum
Sandra Nolte
Christine Allen
Cristiana Abbafati
Marika Nomura
Ole f Norheim
bo Norrving
Jean Jacques n Noubiap
Rita Van Dingenen
Carla Makhlouf Obermeyer
Felix Akpojene Ogbo
In-hwan oh
Anselm Okoro
Olanrewaju Oladimeji
Neeraj Bedi
Andrew Toyin Olagunju
Rajaa Al-raddadi
Pedro r Olivares
Helen e Olsen
Bolajoko Olubukunola Olusanya
Santosh Varughese
Jacob Olusegun Olusanya
John Nelson Opio
Eyal Oren
Alberto Ortiz
Ettore Beghi
Richard h Osborne
Majdi Osman
Mayowa o Owolabi
Ubai Alsharif
Mahesh pa
Amanda w Pain
Tommi Vasankari
Smita Pakhale
Elizabeth Palomares Castillo
Adrian Pana
Yannick Béjot
Christina Papachristou
Mahboubeh Parsaeian
Tejas Patel
George c Patton
Deepak Paudel
Khalid a Altirkawi
Vinod k Paul
Narayanaswamy Venketasubramanian
Neil Pearce
David m Pereira
Aminu k Bello
Rogelio Perez-padilla
Fernando Perez-ruiz
Norberto Perico
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Max Petzold
Michael Robert Phillips
David m Pigott
Elena Alvarez Martin
Francesco s Violante
Julian David Pillay
Jiandong Sun
Christine Pinho
Suzanne Polinder
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v Prakash
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d Alex Quistberg
Amir Radfar
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Marissa Reitsma
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Mohammad Sadegh Rezai
Antonio Luiz Pinho Ribeiro
Hirbo Shore Roba
Erfan Amini
Mohammad Bagher Rokni
Luca Ronfani
Gholamreza Roshandel
Gregory a Roth
Eduardo Bernabé
Dietrich Rothenbacher
Nawal k Roy
Stein Emil Vollset
Perminder s Sachdev
Ben Benasco Sackey
Mohammad Yahya Saeedi
Saeid Safiri
Walid Ammar
Rajesh Sagar
Mohammad Ali Sahraian
Oscar Alberto Bernal
Muhammad Muhammad Saleh
Joshua a Salomon
Abdallah m Samy
Theo Vos
Juan Ramon Sanabria
Maria Dolores Sanchez-niño
Logan Sandar
Itamar s Santos
João Vasco Santos
Joshu Amo-adjei
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Milena m Santric Milicevic
Rodrigo Sarmiento-suarez
Benn Sartorius
Maheswar Satpathy
Joseph a Wagner
Miloje Savic
Monika Sawhney
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Ryan Mbarber
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Mansour Shamsipour
Sheikh Mohammed Shariful Islam
Jayendra Sharma
Tariku Jibat Beyene
Rajesh Sharma
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Sara Sheikhbahaei
Jiabin Shen
Peilin Shi
Sofia Androudi
Mika Shigematsu
Judd l Walson
Min-jeong Shin
Rahman Shiri
Zulfiqar a Bhutta
Haitham Shoman
Mark g Shrime
Ephrem Lejore Sibamo Sibamo
Inga Dora Sigfusdottir
Diego Augusto Santos Silva
Dayane Gabriele Alves Silveira
Shireen Sindi
Hossein Ansari
Haidong Wang
Abhishek Singh
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Yuan-pang Wang
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Mustafa Geleto Ansha
Eugene Sobngwi
Samir Soneji
Joan b Soriano
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Andrea Werdecker
Joshua Wesana
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Harvey a Whiteford
James d Wilkinson
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Charles d a Wolfe
Suleman Atique
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Sungho Won
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Shimelash Bitew Workie
Mamo Wubshet
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Gelin xu
Ajit Kumar Yadav
Mohsen Yaghoubi
Bereket Yakob
Lijing l Yan
Charles Birungi
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Yuichiro Yano
Mehdi Yaseri
Hassen Hamid Yimam
Paul Yip
Naohiro Yonemoto
Stan Biryukov
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Habtamu Mellie Bizuayehu
Dipan Bose
Foad Abd-allah
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Soumya Swaminathan
Michael Brauer
Alexandra Brazinova
Nicholas j k Breitborde
Hermann Brenner
Zahid a Butt
Rosario Cárdenas
Lucero Cahuana-hurtado
Ismael Ricardo Campos-nonato
Josip Car
Abdishakur m Abdulle
Johan Ärnlöv
Juan Jesus Carrero
Daniel Casey
Valeria Caso
Carlos a Castañeda-orjuela
Jacqueline Castillo Rivas
Ferrán Catalá-lópez
Pedro Cecilio
Kelly Cercy
Fiona j Charlson
Alan z Chen
Bryan l Sykes
Ahmed Abdulahi Abdurahman
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dc.contributor.author.fl_str_mv Chandrashekhar t Sreeramareddy
Vasiliki Stathopoulou
Nicholas Steel
Caitlyn Steiner
Sabine Steinke
Ellen Nolte
Carl Abelardo t Antonio
Mark Andrew Stokes
Saverio Stranges
Mark Strong
Konstantinos Stroumpoulis
Adrienne Chew
Mirriam Chibalabala
Chioma Ezinne Chibueze
Vesper Hichilombwe Chisumpa
Abdulaal a Chitheer
Rajiv Chowdhury
Hanne Christensen
Devasahayam Jesudas Christopher
Liliana g Ciobanu
Rafael Tabarés-seisdedos
Seok-jun Yoon
Massimo Cirillo
Semaw Ferede Abera
Megan s Coggeshall
Leslie Trumbull Cooper
Monica Cortinovis
John a Crump
Koustuv Dalal
Hadi Danawi
Lalit Dandona
Rakhi Dandona
Mustafa z Younis
Karen m Tabb
Paul i Dargan
Jose Das Neves
Biju Abraham
Gail Davey
Dragos v Davitoiu
Kairat Davletov
Diego de Leo
Liana c Del Gobbo
Borja Del Pozo-cruz
Chuanhua yu
Robert p Dellavalle
Getachew Redae Taffere
Kebede Deribe
Amare Deribew
Don c Des Jarlais
Girmatsion Fisseha Abreha
Subhojit Dey
Samath d Dharmaratne
Daniel Dicker
Eric l Ding
Zoubida Zaidi
Klara Dokova
e Ray Dorsey
Roberto Tchio Talongwa
Kerrie e Doyle
Manisha Dubey
Rebecca Ehrenkranz
Christian Lycke Ellingsen
Kelemework Adane
Iqbal Elyazar
Ahmadali Enayati
Maysaa el Sayed Zaki
Sergey Petrovich Ermakov
Babak Eshrati
Alireza Esteghamati
Musharaf Tarajia
Kara Estep
Thomas Fürst
Imad d a Faghmous
Fanuel Belayneh Bekele Fanuel
Emerito Jose Aquino Faraon
Ademola Lukman Adelekan
Sachin r Atre
Talha a Farid
Carla Sofia e sa Farinha
Andre Faro
Maryam s Farvid
Mohammad Tavakkoli
Farshad Farzadfar
Valery l Feigin
Andrea b Feigl
Seyed-mohammad Fereshtehnejad
Jefferson g Fernandes
Carlos Zambrana-torrelio
João c Fernandes
Ifedayo Morayo o Adetifa
Tesfaye Regassa Feyissa
Florian Fischer
Christina Fitzmaurice
Nuno Taveira
Thomas d Fleming
Nataliya Foigt
Kyle j Foreman
Mohammad h Forouzanfar
Tomas Zapata
Richard c Franklin
Joseph Frostad
Tsegaye Tewelde G/hiwot
Nancy Fullman
Ashkan Afshin
Emmanuela Gakidou
Stephanie Teeple
Ketevan Gambashidze
Amiran Gamkrelidze
Wayne Gao
Zerihun Menlkalew Zenebe
Alberto l Garcia-basteiro
Teshome Gebre
Amanuel Tesfay Gebremedhin
Mengistu Welday Gebremichael
Alemseged Aregay Gebru
Amha Admasie Gelaye
Arnav Agarwal
Teketo Kassaw Tegegne
Johanna m Geleijnse
Ricard Genova-maleras
Sanjay Zodpey
Katherine b Gibney
Ababi Zergaw Giref
Melkamu Dedefo Gishu
Giorgia Giussani
William w Godwin
Audra Gold
Ellen m Goldberg
Philimon n Gona
al Artaman
Sanjay Kumar Agarwal
Lela Sturua
Amador Goodridge
Sameer Vali Gopalani
Atsushi Goto
Nicholas Graetz
Felix Greaves
Max Griswold
Peter Imre Guban
Harish Chander Gugnani
Prakash c Gupta
Arash Tehrani-banihashemi
Leo Zoeckler
Rahul Gupta
Sunilkumar Agarwal
Rajeev Gupta
Tanush Gupta
Vipin Gupta
Tesfa Dejenie Habtewold
Nima Hafezi-nejad
Demewoz Haile
Alemayehu Desalegne Hailu
Gessessew Bugssa Hailu
Liesl Joanna Zuhlke
Tesfalidet Tekelab
Alex Hakuzimana
Randah Ribhi Hamadeh
Anurag Agrawal
Mitiku Teshome Hambisa
Samer Hamidi
Mouhanad Hammami
Graeme j Hankey
Yuantao Hao
Hilda l Harb
Christopher j l Murray
Habtamu Abera Hareri
Dejen Yemane Tekle
Josep Maria Haro
Mohammad Sadegh Hassanvand
Rasmus Havmoeller
Aliasghar Ahmad Kiadaliri
Roderick j Hay
Simon i Hay
Delia Hendrie
Ileana Beatriz Heredia-pi
Amanuel Alemu Abajobir
Hans w Hoek
Masako Horino
Girma Temam Shifa
Nobuyuki Horita
h Dean Hosgood
Aung Soe Htet
Guoqing hu
Alireza Ahmadi
Hsiang Huang
John j Huang
Leticia Avila-burgos
Bethany m Huntley
Chantal Huynh
Kim Moesgaard Iburg
Abdullah Sulieman Terkawi
Bogdan Vasile Ileanu
Kaire Innos
Asnake Ararsa Irenso
Nader Jahanmehr
Mihajlo b Jakovljevic
Kedir Yimam Ahmed
Euripide Frinel g Arthur Avokpaho
Peter James
Spencer Lewis James
Mehdi Javanbakht
Sudha p Jayaraman
Azeb Gebresilassie Tesema
Achala Upendra Jayatilleke
Panniyammakal Jeemon
Vivekanand Jha
Denny John
Catherine Johnson
Beatriz Paulina Ayala Quintanilla
Sarah c Johnson
Muktar Beshir Ahmed
Jost b Jonas
Knud Juel
Zubair Kabir
js Thakur
Yogeshwar Kalkonde
Ritul Kamal
Haidong Kan
Andre Karch
Ashish Awasthi
Corine Kakizi Karema
Seyed m Karimi
Amir Kasaeian
Rufus Olusola Akinyemi
Nicholas j Kassebaum
Anshul Kastor
Alan j Thomson
Srinivasa Vittal Katikireddi
Konstantin Kazanjan
Peter Njenga Keiyoro
Nebiyu Negussu Ayele
Laura Kemmer
Andrew Haddon Kemp
Andre Pascal Kengne
Amene Abebe Kerbo
Maia Kereselidze
Reed j d Sorensen
Tomi f Akinyemiju
Taavi Tillmann
Chandrasekharan Nair Kesavachandran
Yousef Saleh Khader
Peter Azzopardi
Ibrahim Khalil
Abdur Rahman Khan
Ejaz Ahmad Khan
Gulfaraz Khan
Young-ho Khang
Abdullah Tawfih Abdullah Khoja
Irma Khonelidze
Jagdish Khubchandani
Tenaw Yimer Tiruye
Nadia Akseer
Muawiyyah Babale Sufiyan
Getiye Dejenu Kibret
Daniel Kim
Pauline Kim
Yun Jin Kim
Ruth w Kimokoti
Yohannes Kinfu
Niranjan Kissoon
Miia Kivipelto
Yoshihiro Kokubo
Hamid Asayesh
Huda Omer ba Saleem
Anneli Kolk
Ziyad Al-aly
Dhaval Kolte
Jacek a Kopec
Soewarta Kosen
Parvaiz a Koul
ai Koyanagi
Michael Kravchenko
Sanjay Krishnaswami
Kristopher j Krohn
Till Bärnighausen
Ruoyan Tobe-gai
Barthelemy Kuate Defo
Burcu Kucuk Bicer
Khurshid Alam
Ernst j Kuipers
Veena s Kulkarni
g Anil Kumar
Fekede Asefa Kumsa
Michael Kutz
Hmwe h Kyu
Umar Bacha
Anton Carl Jonas Lager
Marcello Tonelli
Aparna Lal
Dharmesh Kumar Lal
Ratilal Lalloo
Noore Alam
Tea Lallukka
Qing Lan
Sinead m Langan
Van c Lansingh
Alaa Badawi
Heidi j Larson
Anders Larsson
Roman Topor-madry
Dennis Odai Laryea
Asma Abdul Latif
Alicia Elena Beatriz Lawrynowicz
Janet l Leasher
Sayed Saidul Alam
James Leigh
Mall Leinsalu
Kalkidan Hassen Abate
Cheru Tesema Leshargie
Janni Leung
Ricky Leung
Miguel Tortajada
Miriam Levi
Xiaofeng Liang
Stephen s Lim
Margaret Lind
Shai Linn
Zewdie Aderaw Alemu
Amitava Banerjee
Steven e Lipshultz
Patrick Liu
Yang Liu
Loon-tzian lo
Christopher Troeger
Giancarlo Logroscino
Alan d Lopez
Scott a Lorch
Paulo a Lotufo
Rafael Lozano
Aleksandra Barac
Raimundas Lunevicius
Kefyalew Addis Alene
Ronan a Lyons
Erlyn Rachelle King Macarayan
Mark t Mackay
Thomas Truelsen
Hassan Magdy Abd el Razek
Mohammed Magdy Abd el Razek
Mahdi Mahdavi
Azeem Majeed
Miguel a Barboza
Reza Malekzadeh
Deborah Carvalho Malta
Lorenzo g Mantovani
Lily Alexander
Tsegahun Manyazewal
Chabila c Mapoma
Abera Kenay Tura
Wagner Marcenes
Guy b Marks
Neal Marquez
Suzanne l Barker-collo
Jose Martinez-raga
Melvin Barrientos Marzan
João Massano
Manu Raj Mathur
Pallab k Maulik
Raghib Ali
Mohsen Mazidi
Uche s Uchendu
Colm Mcalinden
John j Mcgrath
Lope h Barrero
Claire Mcnellan
Peter a Meaney
Alem Mehari
Man Mohan Mehndiratta
Toni Meier
Alemayehu b Mekonnen
Kidanu Gebremariam Meles
Thomas Bollyky
Kingsley n Ukwaja
Syed Danish Ali
Rizwan Abdulkader Suliankatchi
Ziad a Memish
Melkamu Merid Mengesha
Desalegn Tadese Mengiste
Mubarek Abera Mengistie
Bereket Gebremichael Menota
George a Mensah
Seid Tiku Mereta
Atte Meretoja
Tuomo j Meretoja
Eduardo a Undurraga
Sanjay Basu
Haftay Berhane Mezgebe
Reza Alizadeh-navaei
Renata Micha
Anoushka Millear
Edward j Mills
Shawn Minnig
Mojde Mirarefin
Erkin m Mirrakhimov
Charles n Mock
Karzan Abdulmuhsin Mohammad
Bernhard t Baune
Reza Assadi
Shafiu Mohammed
Sanjay k Mohanty
Ala'a Alkerwi
Ali h Mokdad
Glen Liddell d Mola
Mariam Molokhia
Lorenzo Monasta
Marcella Montico
Maziar Moradi-lakeh
Kaleab Baye
Paula Moraga
Chigozie Jesse Uneke
Lidia Morawska
Rintaro Mori
Mark Moses
François Alla
Ulrich o Mueller
Srinivas Murthy
Kamarul Imran Musa
Jean b Nachega
Yibeltal Tebekaw Bayou
Chie Nagata
Gabriele Nagel
Olalekan a Uthman
Mohsen Naghavi
Aliya Naheed
Luigi Naldi
Vinay Nangia
Peter Allebeck
Bruno Ramos Nascimento
Ionut Negoi
Shahrzad Bazargan-hejazi
Sudan Prasad Neupane
Charles r Newton
Marie ng
Job f m Van Boven
Frida Namnyak Ngalesoni
Josephine Wanjiku Ngunjiri
Grant Nguyen
Dina Nur Anggraini Ningrum
Sandra Nolte
Christine Allen
Cristiana Abbafati
Marika Nomura
Ole f Norheim
bo Norrving
Jean Jacques n Noubiap
Rita Van Dingenen
Carla Makhlouf Obermeyer
Felix Akpojene Ogbo
In-hwan oh
Anselm Okoro
Olanrewaju Oladimeji
Neeraj Bedi
Andrew Toyin Olagunju
Rajaa Al-raddadi
Pedro r Olivares
Helen e Olsen
Bolajoko Olubukunola Olusanya
Santosh Varughese
Jacob Olusegun Olusanya
John Nelson Opio
Eyal Oren
Alberto Ortiz
Ettore Beghi
Richard h Osborne
Majdi Osman
Mayowa o Owolabi
Ubai Alsharif
Mahesh pa
Amanda w Pain
Tommi Vasankari
Smita Pakhale
Elizabeth Palomares Castillo
Adrian Pana
Yannick Béjot
Christina Papachristou
Mahboubeh Parsaeian
Tejas Patel
George c Patton
Deepak Paudel
Khalid a Altirkawi
Vinod k Paul
Narayanaswamy Venketasubramanian
Neil Pearce
David m Pereira
Aminu k Bello
Rogelio Perez-padilla
Fernando Perez-ruiz
Norberto Perico
Konrad Pesudovs
Max Petzold
Michael Robert Phillips
David m Pigott
Elena Alvarez Martin
Francesco s Violante
Julian David Pillay
Jiandong Sun
Christine Pinho
Suzanne Polinder
Constance d Pond
v Prakash
Manorama Purwar
Mostafa Qorbani
d Alex Quistberg
Amir Radfar
Anwar Rafay
Sergey k Vladimirov
Derrick a Bennett
Martin Mckee
Nelson Alvis-guzman
Kazem Rahimi
Vafa Rahimi-movaghar
Mahfuzar Rahman
Mohammad Hifz ur Rahman
Rajesh Kumar Rai
Usha Ram
Saleem m Rana
Zane Rankin
Isabela m Bensenor
Vasiliy Victorovich Vlassov
Paturi Vishnupriya Rao
Puja c Rao
Azmeraw t Amare
Salman Rawaf
Maria Albertina Santiago Rego
Marissa Reitsma
Giuseppe Remuzzi
Andre m n n Renzaho
Serge Resnikoff
Adugnaw Berhane
Satar Rezaei
Ayalew Astatkie
Mohammad Sadegh Rezai
Antonio Luiz Pinho Ribeiro
Hirbo Shore Roba
Erfan Amini
Mohammad Bagher Rokni
Luca Ronfani
Gholamreza Roshandel
Gregory a Roth
Eduardo Bernabé
Dietrich Rothenbacher
Nawal k Roy
Stein Emil Vollset
Perminder s Sachdev
Ben Benasco Sackey
Mohammad Yahya Saeedi
Saeid Safiri
Walid Ammar
Rajesh Sagar
Mohammad Ali Sahraian
Oscar Alberto Bernal
Muhammad Muhammad Saleh
Joshua a Salomon
Abdallah m Samy
Theo Vos
Juan Ramon Sanabria
Maria Dolores Sanchez-niño
Logan Sandar
Itamar s Santos
João Vasco Santos
Joshu Amo-adjei
Addisu Shunu Beyene
Milena m Santric Milicevic
Rodrigo Sarmiento-suarez
Benn Sartorius
Maheswar Satpathy
Joseph a Wagner
Miloje Savic
Monika Sawhney
Mete i Saylan
Ben Schöttker
Aletta e Schutte
Ryan Mbarber
David c Schwebel
Yaw Ampem Amoako
Soraya Seedat
Abdulbasit Musa Seid
Canaan Negash Seifu
Tolassa Wakayo
Sadaf g Sepanlou
Berrin Serdar
Edson e Servan-mori
Tesfaye Setegn
Kaja m Abbas
Katya Anne Shackelford
Amira Shaheen
Saeid Shahraz
Benjamin o Anderson
Masood Ali Shaikh
Marina Shakh-nazarova
Stephen g Waller
Mansour Shamsipour
Sheikh Mohammed Shariful Islam
Jayendra Sharma
Tariku Jibat Beyene
Rajesh Sharma
Jun She
Sara Sheikhbahaei
Jiabin Shen
Peilin Shi
Sofia Androudi
Mika Shigematsu
Judd l Walson
Min-jeong Shin
Rahman Shiri
Zulfiqar a Bhutta
Haitham Shoman
Mark g Shrime
Ephrem Lejore Sibamo Sibamo
Inga Dora Sigfusdottir
Diego Augusto Santos Silva
Dayane Gabriele Alves Silveira
Shireen Sindi
Hossein Ansari
Haidong Wang
Abhishek Singh
Patrick Sur
Jasvinder a Singh
om Prakash Singh
Prashant Kumar Singh
Virendra Singh
Abiy Hiruye Sinke
Aklilu Endalamaw Sinshaw
Vegard Skirbekk
Karen Sliwa
Alison Smith
Yuan-pang Wang
Sibhatu Biadgilign
Mustafa Geleto Ansha
Eugene Sobngwi
Samir Soneji
Joan b Soriano
Tatiane Cristina Moraes Sousa
Luciano a Sposato
David a Watkins
Elisabete Weiderpass
Tesfay Mehari Atey
Robert g Weintraub
Boris Bikbov
Chi-pang Wen
Andrea Werdecker
Joshua Wesana
Ronny Westerman
Harvey a Whiteford
James d Wilkinson
Charles Shey Wiysonge
Belete Getahun Woldeyes
Charles d a Wolfe
Suleman Atique
Sait Mentes Birlik
Sungho Won
Abdulhalik Workicho
Shimelash Bitew Workie
Mamo Wubshet
Denis Xavier
Gelin xu
Ajit Kumar Yadav
Mohsen Yaghoubi
Bereket Yakob
Lijing l Yan
Charles Birungi
Niguse Tadele Atnafu
Yuichiro Yano
Mehdi Yaseri
Hassen Hamid Yimam
Paul Yip
Naohiro Yonemoto
Stan Biryukov
Donal Bisanzio
Habtamu Mellie Bizuayehu
Dipan Bose
Foad Abd-allah
Michael Brainin
Soumya Swaminathan
Michael Brauer
Alexandra Brazinova
Nicholas j k Breitborde
Hermann Brenner
Zahid a Butt
Rosario Cárdenas
Lucero Cahuana-hurtado
Ismael Ricardo Campos-nonato
Josip Car
Abdishakur m Abdulle
Johan Ärnlöv
Juan Jesus Carrero
Daniel Casey
Valeria Caso
Carlos a Castañeda-orjuela
Jacqueline Castillo Rivas
Ferrán Catalá-lópez
Pedro Cecilio
Kelly Cercy
Fiona j Charlson
Alan z Chen
Bryan l Sykes
Ahmed Abdulahi Abdurahman
dc.subject.por.fl_str_mv Global Burden of Disease
Mortality
Personal Health
topic Global Burden of Disease
Mortality
Personal Health
Carga Global da Doença
Registros de Mortalidade
Registros de Saúde Pessoal
dc.subject.other.pt_BR.fl_str_mv Carga Global da Doença
Registros de Mortalidade
Registros de Saúde Pessoal
description Background National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015.Methods We mapped the most widely used list of causes amenable to personal health care developed by Nolte and McKee to 32 GBD causes. We accounted for variations in cause of death certification and misclassifications through the extensive data standardisation processes and redistribution algorithms developed for GBD. To isolate the effects of personal health-care access and quality, we risk-standardised cause-specific mortality rates for each geography-year by removing the joint effects of local environmental and behavioural risks, and adding back the global levels of risk exposure as estimated for GBD 2015. We employed principal component analysis to create a single, interpretable summary measure–the Healthcare Quality and Access (HAQ) Index–on a scale of 0 to 100. The HAQ Index showed strong convergence validity as compared with other health-system indicators, including health expenditure per capita (r=0·88), an index of 11 universal health coverage interventions (r=0·83), and human resources for health per 1000 (r=0·77). We used free disposal hull analysis with bootstrapping to produce a frontier based on the relationship between the HAQ Index and the Socio-demographic Index (SDI), a measure of overall development consisting of income per capita, average years of education, and total fertility rates. This frontier allowed us to better quantify the maximum levels of personal health-care access and quality achieved across the development spectrum, and pinpoint geographies where gaps between observed and potential levels have narrowed or widened over time.Findings Between 1990 and 2015, nearly all countries and territories saw their HAQ Index values improve; nonetheless, the difference between the highest and lowest observed HAQ Index was larger in 2015 than in 1990, ranging from 28·6 to 94·6. Of 195 geographies, 167 had statistically significant increases in HAQ Index levels since 1990, with South Korea, Turkey, Peru, China, and the Maldives recording among the largest gains by 2015. Performance on the HAQ Index and individual causes showed distinct patterns by region and level of development, yet substantial heterogeneities emerged for several causes, including cancers in highest-SDI countries; chronic kidney disease, diabetes, diarrhoeal diseases, and lower respiratory infections among middle-SDI countries; and measles and tetanus among lowest-SDI countries. While the global HAQ Index average rose from 40·7 (95% uncertainty interval, 39·0–42·8) in 1990 to 53·7 (52·2–55·4) in 2015, far less progress occurred in narrowing the gap between observed HAQ Index values and maximum levels achieved; at the global level, the difference between the observed and frontier HAQ Index only decreased from 21·2 in 1990 to 20·1 in 2015. If every country and territory had achieved the highest observed HAQ Index by their corresponding level of SDI, the global average would have been 73·8 in 2015. Several countries, particularly in eastern and western sub-Saharan Africa, reached HAQ Index values similar to or beyond their development levels, whereas others, namely in southern sub-Saharan Africa, the Middle East, and south Asia, lagged behind what geographies of similar development attained between 1990 and 2015. Interpretation This novel extension of the GBD Study shows the untapped potential for personal health-care access and quality improvement across the development spectrum. Amid substantive advances in personal health care at the national level, heterogeneous patterns for individual causes in given countries or territories suggest that few places have consistently achieved optimal health-care access and quality across health-system functions and therapeutic areas. This is especially evident in middle-SDI countries, many of which have recently undergone or are currently experiencing epidemiological transitions. The HAQ Index, if paired with other measures of health-system haracteristics such as intervention coverage, could provide a robust avenue for tracking progress on universal health coverage and identifying local priorities for strengthening personal health-care quality and access throughout the world.
publishDate 2017
dc.date.issued.fl_str_mv 2017-07-15
dc.date.accessioned.fl_str_mv 2023-06-28T23:14:55Z
dc.date.available.fl_str_mv 2023-06-28T23:14:55Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/55521
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.1016/S0140-6736(17)30818-8
dc.identifier.issn.pt_BR.fl_str_mv 01406736
dc.identifier.orcid.pt_BR.fl_str_mv https://orcid.org/0000-0001-5689-3870
url https://doi.org/10.1016/S0140-6736(17)30818-8
http://hdl.handle.net/1843/55521
https://orcid.org/0000-0001-5689-3870
identifier_str_mv 01406736
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv The Lancet
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv ENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA
MED - DEPARTAMENTO DE CLÍNICA MÉDICA
MED - DEPARTAMENTO DE PEDIATRIA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
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