A tetravalent dengue nanoparticle stimulates antibody production in mice.

Detalhes bibliográficos
Autor(a) principal: Silva, Elisângela
Data de Publicação: 2012
Outros Autores: Orsi, Mariana, Andrade, Ângela Leão, Domingues, Rosana Zacarias, Silva, Breno de Mello, Araújo, Helena de, Pimenta, Paulo Filemon Paolucci, Diamond, Michael, Rocha, Eliseu, Kroon, Erna Geessien, Malaquias, Luiz Cosme Cotta, Coelho, Luiz
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFOP
Texto Completo: http://www.repositorio.ufop.br/handle/123456789/7383
https://doi.org/10.1186/1477-3155-10-13
Resumo: Dengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However, a subset of patients experiencing secondary infection with a different serotype progresses to the severe form of the disease, dengue hemorrhagic fever/dengue shock syndrome. Currently, there are no licensed vaccines or antiviral drugs to prevent or treat dengue infections. Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines.
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spelling Silva, ElisângelaOrsi, MarianaAndrade, Ângela LeãoDomingues, Rosana ZacariasSilva, Breno de MelloAraújo, Helena dePimenta, Paulo Filemon PaolucciDiamond, MichaelRocha, EliseuKroon, Erna GeessienMalaquias, Luiz Cosme CottaCoelho, Luiz2017-03-16T13:34:41Z2017-03-16T13:34:41Z2012SILVA, E. F. et al. A tetravalent dengue nanoparticle stimulates antibody production in mice. Journal of Nanobiotechnology, v. 10, p. 13, 2012. Disponível em: <https://jnanobiotechnology.biomedcentral.com/articles/10.1186/1477-3155-10-13> Acesso em: 19 fev. 2017.1477-3155http://www.repositorio.ufop.br/handle/123456789/7383https://doi.org/10.1186/1477-3155-10-13Dengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However, a subset of patients experiencing secondary infection with a different serotype progresses to the severe form of the disease, dengue hemorrhagic fever/dengue shock syndrome. Currently, there are no licensed vaccines or antiviral drugs to prevent or treat dengue infections. Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: o próprio artigo.info:eu-repo/semantics/openAccessInactivated Dengue vírusNanoparticlesHumoral responseA tetravalent dengue nanoparticle stimulates antibody production in mice.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleporreponame:Repositório Institucional da UFOPinstname:Universidade Federal de Ouro Preto (UFOP)instacron:UFOPLICENSElicense.txtlicense.txttext/plain; charset=utf-8924http://www.repositorio.ufop.br/bitstream/123456789/7383/2/license.txt62604f8d955274beb56c80ce1ee5dcaeMD52ORIGINALARTIGO_TetravalentDengueNanoparticle.pdfARTIGO_TetravalentDengueNanoparticle.pdfapplication/pdf557851http://www.repositorio.ufop.br/bitstream/123456789/7383/1/ARTIGO_TetravalentDengueNanoparticle.pdfeab656b5a62e97b933690a46b5145411MD51123456789/73832019-11-01 09:10:37.494oai:localhost: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ório InstitucionalPUBhttp://www.repositorio.ufop.br/oai/requestrepositorio@ufop.edu.bropendoar:32332019-11-01T13:10:37Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)false
dc.title.pt_BR.fl_str_mv A tetravalent dengue nanoparticle stimulates antibody production in mice.
title A tetravalent dengue nanoparticle stimulates antibody production in mice.
spellingShingle A tetravalent dengue nanoparticle stimulates antibody production in mice.
Silva, Elisângela
Inactivated Dengue vírus
Nanoparticles
Humoral response
title_short A tetravalent dengue nanoparticle stimulates antibody production in mice.
title_full A tetravalent dengue nanoparticle stimulates antibody production in mice.
title_fullStr A tetravalent dengue nanoparticle stimulates antibody production in mice.
title_full_unstemmed A tetravalent dengue nanoparticle stimulates antibody production in mice.
title_sort A tetravalent dengue nanoparticle stimulates antibody production in mice.
author Silva, Elisângela
author_facet Silva, Elisângela
Orsi, Mariana
Andrade, Ângela Leão
Domingues, Rosana Zacarias
Silva, Breno de Mello
Araújo, Helena de
Pimenta, Paulo Filemon Paolucci
Diamond, Michael
Rocha, Eliseu
Kroon, Erna Geessien
Malaquias, Luiz Cosme Cotta
Coelho, Luiz
author_role author
author2 Orsi, Mariana
Andrade, Ângela Leão
Domingues, Rosana Zacarias
Silva, Breno de Mello
Araújo, Helena de
Pimenta, Paulo Filemon Paolucci
Diamond, Michael
Rocha, Eliseu
Kroon, Erna Geessien
Malaquias, Luiz Cosme Cotta
Coelho, Luiz
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Elisângela
Orsi, Mariana
Andrade, Ângela Leão
Domingues, Rosana Zacarias
Silva, Breno de Mello
Araújo, Helena de
Pimenta, Paulo Filemon Paolucci
Diamond, Michael
Rocha, Eliseu
Kroon, Erna Geessien
Malaquias, Luiz Cosme Cotta
Coelho, Luiz
dc.subject.por.fl_str_mv Inactivated Dengue vírus
Nanoparticles
Humoral response
topic Inactivated Dengue vírus
Nanoparticles
Humoral response
description Dengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However, a subset of patients experiencing secondary infection with a different serotype progresses to the severe form of the disease, dengue hemorrhagic fever/dengue shock syndrome. Currently, there are no licensed vaccines or antiviral drugs to prevent or treat dengue infections. Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2017-03-16T13:34:41Z
dc.date.available.fl_str_mv 2017-03-16T13:34:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, E. F. et al. A tetravalent dengue nanoparticle stimulates antibody production in mice. Journal of Nanobiotechnology, v. 10, p. 13, 2012. Disponível em: <https://jnanobiotechnology.biomedcentral.com/articles/10.1186/1477-3155-10-13> Acesso em: 19 fev. 2017.
dc.identifier.uri.fl_str_mv http://www.repositorio.ufop.br/handle/123456789/7383
dc.identifier.issn.none.fl_str_mv 1477-3155
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1186/1477-3155-10-13
identifier_str_mv SILVA, E. F. et al. A tetravalent dengue nanoparticle stimulates antibody production in mice. Journal of Nanobiotechnology, v. 10, p. 13, 2012. Disponível em: <https://jnanobiotechnology.biomedcentral.com/articles/10.1186/1477-3155-10-13> Acesso em: 19 fev. 2017.
1477-3155
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https://doi.org/10.1186/1477-3155-10-13
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