Treatment of Chagas cardiomyopathy.
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Publication Date: | 2013 |
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Language: | eng |
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Download full: | http://www.repositorio.ufop.br/handle/123456789/3814 http://dx.doi.org/10.1155/2013/849504 |
Summary: | Chagas’ disease (ChD), caused by the protozoa Trypanosoma cruzi (T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still bringsmuch misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in South America. It is an increasing worldwide problem due to the number of cases in endemic areas and the migration of infected subjects tomore developed regions, mainly North America and Europe. Despite its importance, chronic chagas cardiomyopathy (CCC) pathophysiology is yet poorly understood, and independently of its social, clinical, and epidemiological importance, the therapeutic approach of CCC is still transposed from the knowledge acquired from other cardiomyopathies. Therefore, the objective of this review is to describe the treatment of Chagas cardiomyopathy with emphasis on its peculiarities. |
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Botoni, Fernando AntônioRibeiro, Antônio Luiz PinhoMarinho, Carolina CoimbraLima, Marcia Maria OliveiraNunes, Maria do Carmo PereiraRocha, Manoel Otávio da Costa2014-11-12T18:25:55Z2014-11-12T18:25:55Z2013BOTONI, F. A. et al. Treatment of Chagas cardiomyopathy. BioMed Research International, v. 2013, p. 1-9, 2013. Disponível em: <http://www.hindawi.com/journals/bmri/2013/849504/> Acesso em: 01 set. 2014.1110-7243http://www.repositorio.ufop.br/handle/123456789/3814http://dx.doi.org/10.1155/2013/849504Chagas’ disease (ChD), caused by the protozoa Trypanosoma cruzi (T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still bringsmuch misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in South America. It is an increasing worldwide problem due to the number of cases in endemic areas and the migration of infected subjects tomore developed regions, mainly North America and Europe. Despite its importance, chronic chagas cardiomyopathy (CCC) pathophysiology is yet poorly understood, and independently of its social, clinical, and epidemiological importance, the therapeutic approach of CCC is still transposed from the knowledge acquired from other cardiomyopathies. Therefore, the objective of this review is to describe the treatment of Chagas cardiomyopathy with emphasis on its peculiarities.Treatment of Chagas cardiomyopathy.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleThis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: Research International <http://www.hindawi.com/journals/bmri/2013/849504/>. Acesso em: 01 set. 2014.info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UFOPinstname:Universidade Federal de Ouro Preto (UFOP)instacron:UFOPLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://www.repositorio.ufop.br/bitstream/123456789/3814/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALARTIGO_TreatmentChagasCardiomyopathy.pdfARTIGO_TreatmentChagasCardiomyopathy.pdfapplication/pdf1146040http://www.repositorio.ufop.br/bitstream/123456789/3814/1/ARTIGO_TreatmentChagasCardiomyopathy.pdf50c5fa1cacae7acd01ad8a9dbbe7803aMD51123456789/38142019-05-08 13:27:01.173oai:localhost: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Repositório InstitucionalPUBhttp://www.repositorio.ufop.br/oai/requestrepositorio@ufop.edu.bropendoar:32332019-05-08T17:27:01Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)false |
dc.title.pt_BR.fl_str_mv |
Treatment of Chagas cardiomyopathy. |
title |
Treatment of Chagas cardiomyopathy. |
spellingShingle |
Treatment of Chagas cardiomyopathy. Botoni, Fernando Antônio |
title_short |
Treatment of Chagas cardiomyopathy. |
title_full |
Treatment of Chagas cardiomyopathy. |
title_fullStr |
Treatment of Chagas cardiomyopathy. |
title_full_unstemmed |
Treatment of Chagas cardiomyopathy. |
title_sort |
Treatment of Chagas cardiomyopathy. |
author |
Botoni, Fernando Antônio |
author_facet |
Botoni, Fernando Antônio Ribeiro, Antônio Luiz Pinho Marinho, Carolina Coimbra Lima, Marcia Maria Oliveira Nunes, Maria do Carmo Pereira Rocha, Manoel Otávio da Costa |
author_role |
author |
author2 |
Ribeiro, Antônio Luiz Pinho Marinho, Carolina Coimbra Lima, Marcia Maria Oliveira Nunes, Maria do Carmo Pereira Rocha, Manoel Otávio da Costa |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Botoni, Fernando Antônio Ribeiro, Antônio Luiz Pinho Marinho, Carolina Coimbra Lima, Marcia Maria Oliveira Nunes, Maria do Carmo Pereira Rocha, Manoel Otávio da Costa |
description |
Chagas’ disease (ChD), caused by the protozoa Trypanosoma cruzi (T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still bringsmuch misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in South America. It is an increasing worldwide problem due to the number of cases in endemic areas and the migration of infected subjects tomore developed regions, mainly North America and Europe. Despite its importance, chronic chagas cardiomyopathy (CCC) pathophysiology is yet poorly understood, and independently of its social, clinical, and epidemiological importance, the therapeutic approach of CCC is still transposed from the knowledge acquired from other cardiomyopathies. Therefore, the objective of this review is to describe the treatment of Chagas cardiomyopathy with emphasis on its peculiarities. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
dc.date.accessioned.fl_str_mv |
2014-11-12T18:25:55Z |
dc.date.available.fl_str_mv |
2014-11-12T18:25:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BOTONI, F. A. et al. Treatment of Chagas cardiomyopathy. BioMed Research International, v. 2013, p. 1-9, 2013. Disponível em: <http://www.hindawi.com/journals/bmri/2013/849504/> Acesso em: 01 set. 2014. |
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http://www.repositorio.ufop.br/handle/123456789/3814 |
dc.identifier.issn.none.fl_str_mv |
1110-7243 |
dc.identifier.doi.none.fl_str_mv |
http://dx.doi.org/10.1155/2013/849504 |
identifier_str_mv |
BOTONI, F. A. et al. Treatment of Chagas cardiomyopathy. BioMed Research International, v. 2013, p. 1-9, 2013. Disponível em: <http://www.hindawi.com/journals/bmri/2013/849504/> Acesso em: 01 set. 2014. 1110-7243 |
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http://www.repositorio.ufop.br/handle/123456789/3814 http://dx.doi.org/10.1155/2013/849504 |
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