Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes

Detalhes bibliográficos
Autor(a) principal: Ferraz, Camila Lousada Herbster
Data de Publicação: 2018
Outros Autores: Mendes, Angela Delmira Nunes, Ferraz, Tania Maria Bulcão Lousada, Silva, Carlos Antonio Bruno da
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Revista Brasileira em Promoção da Saúde
Texto Completo: https://ojs.unifor.br/RBPS/article/view/6993
Resumo: Objectives: To assess the association between vitamin D levels, parameters of metabolic control and presence of microvascular complications in type 1 diabetes mellitus (T1DM) patients. Methods: Analytical and observational cross-sectional study of medical records of fifty patients carried out in 2016 in Fortaleza, Ceará. Clinical and epidemiological data were analyzed: sex, age, BMI (body mass index), skin color, glycemic control, duration of diabetes, daily insulin dose, presence of microvascular complications, and vitamin D assay by chemiluminescence. Fisher’s test, students’s t test and Mann-Whitney U test were used with p< 0.05. Results: Vitamin D deficiency was seen in 34 (68%) patients, with a mean of 25(OH) vitamin D of 23.24±4.29 ng/mL in the Vitamin D deficiency group and 38.22±7.72 ng/mL in the normal Vitamin D group. In addition, 37 patients (78%) exhibited glycated hemoglobin above 7%, which was similar in booth groups. The daily insulin dose in the vitamin D deficiency group was higher than in the normal vitamin D group, 54.81+27.4 vs 55.55+19.2, but with no significant association with vitamin D levels. Vitamin D levels were not associated with clinical and epidemiological such as: sex, age, BMI, skin color, glycemic control, duration of diabetes, daily insulin dose and presence of microvascular complications or insulin daily dose. Conclusion: Vitamin D deficiency was present in most of the T1DM patients analyzed. However, such deficiency was not associated with the clinical and epidemiological variables analyzed.
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spelling Association between vitamin D, glycemic control and microvascular complications in type 1 diabetesAsociación entre la vitamina D, el control glicémico y las complicaciones microvasculares del Diabetes tipo IAssociação entre vitamina D, controle glicêmico e complicações microvasculares no diabetes tipo 1Diabetes MellitusVitamin DMedical Records.Diabetes MellitusVitamina DRegistros Médicos.Diabetes MellitusVitamina DRegistros Médicos.Objectives: To assess the association between vitamin D levels, parameters of metabolic control and presence of microvascular complications in type 1 diabetes mellitus (T1DM) patients. Methods: Analytical and observational cross-sectional study of medical records of fifty patients carried out in 2016 in Fortaleza, Ceará. Clinical and epidemiological data were analyzed: sex, age, BMI (body mass index), skin color, glycemic control, duration of diabetes, daily insulin dose, presence of microvascular complications, and vitamin D assay by chemiluminescence. Fisher’s test, students’s t test and Mann-Whitney U test were used with p< 0.05. Results: Vitamin D deficiency was seen in 34 (68%) patients, with a mean of 25(OH) vitamin D of 23.24±4.29 ng/mL in the Vitamin D deficiency group and 38.22±7.72 ng/mL in the normal Vitamin D group. In addition, 37 patients (78%) exhibited glycated hemoglobin above 7%, which was similar in booth groups. The daily insulin dose in the vitamin D deficiency group was higher than in the normal vitamin D group, 54.81+27.4 vs 55.55+19.2, but with no significant association with vitamin D levels. Vitamin D levels were not associated with clinical and epidemiological such as: sex, age, BMI, skin color, glycemic control, duration of diabetes, daily insulin dose and presence of microvascular complications or insulin daily dose. Conclusion: Vitamin D deficiency was present in most of the T1DM patients analyzed. However, such deficiency was not associated with the clinical and epidemiological variables analyzed.Objetivo: Evaluar la asociación entre los niveles de vitamina D, los parámetros del control metabólico y la presencia de complicaciones microvasculares de pacientes con Diabetes Mellitus Tipo I (DM1). Métodos: Estudio transversal, analítico y observacional realizado en 2016 en Fortaleza, Ceará, con historiales clínicos de cincuenta pacientes. Se investigaron los siguientes datos clínicos y epidemiológicos: el sexo, la edad, el IMC (Índice de Masa Corporal), el color de la piel, el control glicémico, la duración del diabetes, la dosis diaria de insulina, la presencia de complicaciones microvasculares y la dosificación de vitamina D por quimioluminiscencia. Se utilizaron las pruebas ecxato de Fisher, t-Student y Mann-Whitney con p< 0,05. Resultados: Se observó la deficiencia de vitamina D en 34 (68%) pacientes con media de 25(OH) de vitamina D, 23,24 ± 4,29 ng/mL en el grupo de vitamina D deficiente y 38,22± 7,72 ng/mL en el grupo de vitamina D suficiente. Además, 37 pacientes (78%) presentaron hemoglobina glicosilada por encima del 7% y semejante para los dos grupos. La dosis diaria de insulina en el grupo de vitamina D deficiente ha sido mayor que en el grupo de vitamina D suficiente, 54,81 + 27,4 vs 55,55 + 19,2, pero sin asociación significativa con los niveles de vitamina D. El nivel sérico de vitamina D no se ha asociado con los parámetros clínicos y epidemiológicos como el sexo, la edad, el IMC, el color de la piel, el control glicémico, la duración del diabetes, la dosis diaria de insulina y la presencia de complicaciones microvasculares. Conclusión: La deficiencia de vitamina D se dio en la mayoría de los pacientes con DM1 evaluados. Sin embargo, no hubo asociación entre la deficiencia y las variables clínicas y epidemiológicas analizadas.Objetivo: Avaliar a associação entre os níveis de vitamina D, os parâmetros do controle metabólico e a presença de complicações microvasculares em pacientes portadores de diabetes mellitus tipo1 (T1DM). Métodos: Estudo transversal, analítico e observacional, realizado em 2016, em Fortaleza, Ceará, com prontuários de cinquenta pacientes. Investigaram-se os dados clínicos e epidemiológicos: sexo, idade, IMC (índice de massa corporal), cor da pele, controle glicêmico, duração do diabetes, dose diária de insulina, presença de complicações microvasculares e dosagem de vitamina D por quimiluminescência. Utilizaram-se os testes exato de Fisher, t-Student e Mann-Whitney com p< 0,05. Resultados: Observou-se deficiência de vitamina D em 34 (68%) pacientes, com média de 25(OH) de vitamina D, 23,24 ± 4,29 ng/mL no grupo vitamina D deficiente e 38,22± 7,72 ng/mL no grupo vitamina D suficiente. Além disso, 37 pacientes (78%) apresentaram hemoglobina glicada acima de 7% e semelhante nos dois grupos. A dose diária de insulina no grupo vitamina D deficiente foi maior que no grupo vitamina D suficiente, 54,81 + 27,4 vs 55,55 + 19,2, mas sem associação significativa com níveis de vitamina D. O nível sérico da vitamina D não se associou com parâmetros clínicos e epidemiológicos, como: sexo, idade, IMC, cor da pele, controle glicêmico, duração do diabetes, dose diária de insulina e presença de complicações microvasculares. Conclusão: A deficiência de vitamina D esteve presente na maioria dos pacientes com T1DM avaliados. No entanto, sem associação entre essa deficiência e as variáves clínicas e epidemiológicas analisadas.Universidade de Fortaleza2018-06-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion"Peer-reviewed Article""Avaliado pelos pares""Avaliado pelos pares"application/pdfapplication/pdfhttps://ojs.unifor.br/RBPS/article/view/699310.5020/18061230.2018.6993Brazilian Journal in Health Promotion; Vol. 31 No. 2 (2018)Revista Brasileña en Promoción de la Salud; Vol. 31 Núm. 2 (2018)Revista Brasileira em Promoção da Saúde; v. 31 n. 2 (2018)1806-1230reponame:Revista Brasileira em Promoção da Saúdeinstname:Universidade de Fortaleza (Unifor)instacron:UFORporenghttps://ojs.unifor.br/RBPS/article/view/6993/pdfhttps://ojs.unifor.br/RBPS/article/view/6993/pdf_1Copyright (c) 2018 Revista Brasileira em Promoção da Saúdeinfo:eu-repo/semantics/openAccessFerraz, Camila Lousada HerbsterMendes, Angela Delmira NunesFerraz, Tania Maria Bulcão LousadaSilva, Carlos Antonio Bruno da2022-02-16T12:39:23Zoai:ojs.ojs.unifor.br:article/6993Revistahttps://periodicos.unifor.br/RBPS/oai1806-12301806-1222opendoar:2022-02-16T12:39:23Revista Brasileira em Promoção da Saúde - Universidade de Fortaleza (Unifor)false
dc.title.none.fl_str_mv Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes
Asociación entre la vitamina D, el control glicémico y las complicaciones microvasculares del Diabetes tipo I
Associação entre vitamina D, controle glicêmico e complicações microvasculares no diabetes tipo 1
title Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes
spellingShingle Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes
Ferraz, Camila Lousada Herbster
Diabetes Mellitus
Vitamin D
Medical Records.
Diabetes Mellitus
Vitamina D
Registros Médicos.
Diabetes Mellitus
Vitamina D
Registros Médicos.
title_short Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes
title_full Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes
title_fullStr Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes
title_full_unstemmed Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes
title_sort Association between vitamin D, glycemic control and microvascular complications in type 1 diabetes
author Ferraz, Camila Lousada Herbster
author_facet Ferraz, Camila Lousada Herbster
Mendes, Angela Delmira Nunes
Ferraz, Tania Maria Bulcão Lousada
Silva, Carlos Antonio Bruno da
author_role author
author2 Mendes, Angela Delmira Nunes
Ferraz, Tania Maria Bulcão Lousada
Silva, Carlos Antonio Bruno da
author2_role author
author
author
dc.contributor.author.fl_str_mv Ferraz, Camila Lousada Herbster
Mendes, Angela Delmira Nunes
Ferraz, Tania Maria Bulcão Lousada
Silva, Carlos Antonio Bruno da
dc.subject.por.fl_str_mv Diabetes Mellitus
Vitamin D
Medical Records.
Diabetes Mellitus
Vitamina D
Registros Médicos.
Diabetes Mellitus
Vitamina D
Registros Médicos.
topic Diabetes Mellitus
Vitamin D
Medical Records.
Diabetes Mellitus
Vitamina D
Registros Médicos.
Diabetes Mellitus
Vitamina D
Registros Médicos.
description Objectives: To assess the association between vitamin D levels, parameters of metabolic control and presence of microvascular complications in type 1 diabetes mellitus (T1DM) patients. Methods: Analytical and observational cross-sectional study of medical records of fifty patients carried out in 2016 in Fortaleza, Ceará. Clinical and epidemiological data were analyzed: sex, age, BMI (body mass index), skin color, glycemic control, duration of diabetes, daily insulin dose, presence of microvascular complications, and vitamin D assay by chemiluminescence. Fisher’s test, students’s t test and Mann-Whitney U test were used with p< 0.05. Results: Vitamin D deficiency was seen in 34 (68%) patients, with a mean of 25(OH) vitamin D of 23.24±4.29 ng/mL in the Vitamin D deficiency group and 38.22±7.72 ng/mL in the normal Vitamin D group. In addition, 37 patients (78%) exhibited glycated hemoglobin above 7%, which was similar in booth groups. The daily insulin dose in the vitamin D deficiency group was higher than in the normal vitamin D group, 54.81+27.4 vs 55.55+19.2, but with no significant association with vitamin D levels. Vitamin D levels were not associated with clinical and epidemiological such as: sex, age, BMI, skin color, glycemic control, duration of diabetes, daily insulin dose and presence of microvascular complications or insulin daily dose. Conclusion: Vitamin D deficiency was present in most of the T1DM patients analyzed. However, such deficiency was not associated with the clinical and epidemiological variables analyzed.
publishDate 2018
dc.date.none.fl_str_mv 2018-06-21
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
"Peer-reviewed Article"
"Avaliado pelos pares"
"Avaliado pelos pares"
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.unifor.br/RBPS/article/view/6993
10.5020/18061230.2018.6993
url https://ojs.unifor.br/RBPS/article/view/6993
identifier_str_mv 10.5020/18061230.2018.6993
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://ojs.unifor.br/RBPS/article/view/6993/pdf
https://ojs.unifor.br/RBPS/article/view/6993/pdf_1
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista Brasileira em Promoção da Saúde
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista Brasileira em Promoção da Saúde
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade de Fortaleza
publisher.none.fl_str_mv Universidade de Fortaleza
dc.source.none.fl_str_mv Brazilian Journal in Health Promotion; Vol. 31 No. 2 (2018)
Revista Brasileña en Promoción de la Salud; Vol. 31 Núm. 2 (2018)
Revista Brasileira em Promoção da Saúde; v. 31 n. 2 (2018)
1806-1230
reponame:Revista Brasileira em Promoção da Saúde
instname:Universidade de Fortaleza (Unifor)
instacron:UFOR
instname_str Universidade de Fortaleza (Unifor)
instacron_str UFOR
institution UFOR
reponame_str Revista Brasileira em Promoção da Saúde
collection Revista Brasileira em Promoção da Saúde
repository.name.fl_str_mv Revista Brasileira em Promoção da Saúde - Universidade de Fortaleza (Unifor)
repository.mail.fl_str_mv
_version_ 1798313066697326592

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