Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients

Detalhes bibliográficos
Autor(a) principal: Stumm, Glaucia
Data de Publicação: 2022
Outros Autores: Pereira, Vagner, Wolf, Jonas Michel, Furlin, Elisangela, Turcatto, Janaína, Saldanha, Marcelo, Dani, Caroline, Forgiarini, Luiz
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/112032
Resumo: Objective: To determine the risk factors associated with failure in noninvasive mechanical ventilation (NIV) in a pediatric intensive care unit. Methods: Retrospective cohort from medical records of patients admitted to the Pediatric ICU of a Hospital in Caxias do Sul, between May 2017 and October 2019, who used NIV. Results: The incidence of NIV failure was 33%. Asthma patients, post-extubation use, continuous use, closure at night, final SIMV modality, ventilatory parameters, initial PEEP, and final FIO2 were also associated with failure. In vital signs, the initial SBP and the final RF were significant. After multivariate analysis, final SIMV modality, closing at night, final PIP, and final RF were associated with NIV failure. Conclusion: SIMV final ventilatory modality, as well as NIV closure at night, higher final PIP and higher final RF are risk factors for NIV failure.
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spelling Incidence and risk factors associated with non-invasive ventilation failure in pediatric patientsIncidência e fatores de risco associados à falha na ventilação não invasiva em pacientes pediátricosRisk factorsNoninvasive ventilationPediatric Intensive Care UnitRespiratory failureMechanical ventilationPositive-pressure respiration.Objective: To determine the risk factors associated with failure in noninvasive mechanical ventilation (NIV) in a pediatric intensive care unit. Methods: Retrospective cohort from medical records of patients admitted to the Pediatric ICU of a Hospital in Caxias do Sul, between May 2017 and October 2019, who used NIV. Results: The incidence of NIV failure was 33%. Asthma patients, post-extubation use, continuous use, closure at night, final SIMV modality, ventilatory parameters, initial PEEP, and final FIO2 were also associated with failure. In vital signs, the initial SBP and the final RF were significant. After multivariate analysis, final SIMV modality, closing at night, final PIP, and final RF were associated with NIV failure. Conclusion: SIMV final ventilatory modality, as well as NIV closure at night, higher final PIP and higher final RF are risk factors for NIV failure.Introdução: Suporte ventilatório é usado para o tratamento de pacientes com insuficiência respiratória aguda (IRpA) ou crônica agudizada.  Objetivo foi determinar os fatores de risco associados à falha na VNI em uma unidade de terapia intensiva pediátrica.Métodos: Coorte retrospectiva a partir de prontuários de pacientes admitidos na unidade de terapia intensiva (UTI) Pediátrica de um Hospital de Caxias do Sul, entremaio de 2017 e outubro de 2019, que utilizaram VNI.Resultados: Incidência de falha na VNI foi de 33%. Asma (RR = 1,36; IC95% = 1,08- 1,72), uso de VNI em pacientes pós-extubação (RR = 1,97; IC95% = 1,17-3,29), uso contínuo da VNI (RR = 2,44; IC95% = 1,18-5,05), encerramento à noite (RR = 2,52; IC95% = 1,53-4,14), modalidade final ventilação mandatória intermitente sincronizada (SIMV) (RR = 4,20; IC95% = 2,20-7,90), pressão expiratória positiva final (PEEP) no início da ventilação (6,8 ± 1,1; p < 0,01) e fração inspiratória de O2 (FIO2) final (53,10 ± 18,50; p < 0,01) foram associados à falha. Adicionalmente, pressão arterialsistólica (PAS) inicial (118,68 ± 18,68 mmHg; p = 0,02), frequência respiratória inicial (FR) (47,69 ± 14,76; p = 0,28) e final (47,54 ± 14,76; p < 0,01) foram associados a falha.Conclusão: Modalidade ventilatória final SIMV, demostra ser o melhor preditor de risco de falha, seguido do turno em que a VNI é finalizada, onde à noite existe maior risco de falha. Foram preditores de falha, porém com menor robustez, a pressão positiva inspiratória (PIP) final e a FR final.HCPA/FAMED/UFRGS2022-05-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/112032Clinical & Biomedical Research; Vol. 42 No. 1 (2022): Clinical and Biomedical ResearchClinical and Biomedical Research; v. 42 n. 1 (2022): Clinical and Biomedical Research2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/112032/84835Copyright (c) 2022 Clinical and Biomedical Researchhttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessStumm, GlauciaPereira, VagnerWolf, Jonas MichelFurlin, ElisangelaTurcatto, JanaínaSaldanha, MarceloDani, CarolineForgiarini, Luiz2024-01-19T14:12:51Zoai:seer.ufrgs.br:article/112032Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2024-01-19T14:12:51Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
Incidência e fatores de risco associados à falha na ventilação não invasiva em pacientes pediátricos
title Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
spellingShingle Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
Stumm, Glaucia
Risk factors
Noninvasive ventilation
Pediatric Intensive Care Unit
Respiratory failure
Mechanical ventilation
Positive-pressure respiration.
title_short Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
title_full Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
title_fullStr Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
title_full_unstemmed Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
title_sort Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
author Stumm, Glaucia
author_facet Stumm, Glaucia
Pereira, Vagner
Wolf, Jonas Michel
Furlin, Elisangela
Turcatto, Janaína
Saldanha, Marcelo
Dani, Caroline
Forgiarini, Luiz
author_role author
author2 Pereira, Vagner
Wolf, Jonas Michel
Furlin, Elisangela
Turcatto, Janaína
Saldanha, Marcelo
Dani, Caroline
Forgiarini, Luiz
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Stumm, Glaucia
Pereira, Vagner
Wolf, Jonas Michel
Furlin, Elisangela
Turcatto, Janaína
Saldanha, Marcelo
Dani, Caroline
Forgiarini, Luiz
dc.subject.por.fl_str_mv Risk factors
Noninvasive ventilation
Pediatric Intensive Care Unit
Respiratory failure
Mechanical ventilation
Positive-pressure respiration.
topic Risk factors
Noninvasive ventilation
Pediatric Intensive Care Unit
Respiratory failure
Mechanical ventilation
Positive-pressure respiration.
description Objective: To determine the risk factors associated with failure in noninvasive mechanical ventilation (NIV) in a pediatric intensive care unit. Methods: Retrospective cohort from medical records of patients admitted to the Pediatric ICU of a Hospital in Caxias do Sul, between May 2017 and October 2019, who used NIV. Results: The incidence of NIV failure was 33%. Asthma patients, post-extubation use, continuous use, closure at night, final SIMV modality, ventilatory parameters, initial PEEP, and final FIO2 were also associated with failure. In vital signs, the initial SBP and the final RF were significant. After multivariate analysis, final SIMV modality, closing at night, final PIP, and final RF were associated with NIV failure. Conclusion: SIMV final ventilatory modality, as well as NIV closure at night, higher final PIP and higher final RF are risk factors for NIV failure.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Avaliado por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/112032
url https://seer.ufrgs.br/index.php/hcpa/article/view/112032
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/112032/84835
dc.rights.driver.fl_str_mv Copyright (c) 2022 Clinical and Biomedical Research
http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Clinical and Biomedical Research
http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 42 No. 1 (2022): Clinical and Biomedical Research
Clinical and Biomedical Research; v. 42 n. 1 (2022): Clinical and Biomedical Research
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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