Effect of Roux-en-Y gastric bypass in the control of erosive esophagitis

• Autor(a) principal: Albuquerque, Antônio Benincá
• Data de Publicação: 2019
• Outros Autores: Rovani, André Luca Boeira, Puhl, Bruna Schmitt, Giacometti, Carlos Roberto, da Silva, Eduardo Dombroski, Jablonski, Elisa Estivalete, Carlotto, Fernanda Marcante, Burtet, Fernanda Tisott, da Silva, Jaline Ribeiro, Belke, Larissa, Madalosso, Carlos Augusto Scussel, Navarini, Daniel
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Clinical and Biomedical Research
• Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/91178
• topic: Erosive esophagitis; GERD; bariatric surgery; obesity; comorbidity

Background: Gastroesophageal reflux disease (GERD) is a multifactorial disease associated with environmental and genetic factors. Obesity is among the risk factors for its development, which also correlates with an increase in severity of clinical presentation and a higher incidence of complications associated with reflux.Aims: To evaluate the impact of Roux-en-Y gastric bypass on the control of erosive esophagitis and metabolic and anthropometric parameters related to obesity.Methods: This historical cohort study included a sample of 249 patients who had undergone bariatric surgery using the Roux-en-Y gastric bypass technique at the Hospital São Vicente de Paulo, Passo Fundo, southern Brazil, from January 2014 to December 2015. Results: Of 249 patients, 77.9% (190 patients) were female and the mean age was 38 years. The occurrence of reflux esophagitis was 81.1% (196 patients) in the preoperative period and 31.3% (75 patients) in the postoperative period. With regard to bariatric treatment response to control moderate and severe esophagitis (grades B, C and D), there was a reduction in prevalence from 62 (25%) to 12 (5%) patients (p<0.05).  Conclusion: Bariatric surgery using the Roux-en-Y gastric bypass technique is effective in the control of reflux esophagitis. Regression is observed mainly in cases of moderate and severe esophagitis.Keywords: Erosive esophagitis; GERD; bariatric surgery; obesity; comorbidity