Exposure to environmental contaminants during pregnancy and its effects in the fetal well-being: a review

• Autor(a) principal: M. Peres, Rossana
• Data de Publicação: 2022
• Outros Autores: T. V. Sanseverino, Maria, Schüler-Faccini, Lavínia
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Clinical and Biomedical Research
• Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/126045
• topic: Contaminantes ambientais; defeitos congênitos; teratogênese; abortos; natimortos; prematuridade; Environmental contaminant; birth defects; teratogenesis; abortions; stillbirths; prematurity

Human exposure to environmental contaminants is omnipresent. A great concern about individuals who live near hazardous waste sites is the potential risk of adverse pregnancy outcomes, especially birth defects. Additionally, with the exception of mercury, lead and PCBs, there is not clear evidence of the teratogenicity caused by other environmental contaminants due to methodological difficulties. Unlike animal experiments, people are rarely exposed to a single hazardous contaminant. However, most of the information documenting adverse reproductive health effects from environmental contaminants originated from studies focused on exposure to single chemicals, and there is little information available on how two or more contaminants affect human pregnancies. This paper reviews the methodological approaches used to access the adverse outcomes of pregnancies exposed to environmentalcontaminants and its major results.