Human Respiratory Syncytial Virus and Human Metapneumovirus
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Clinical and Biomedical Research |
Texto Completo: | https://seer.ufrgs.br/index.php/hcpa/article/view/8065 |
Resumo: | The human respiratory syncytial virus (hRSV) and the human metapneumovírus (hMPV) are main etiological agents of acute respiratory infections (ARI). The ARI is an important cause of childhood morbidity and mortality worldwide. hRSV and hMPV are members of the Paramyxoviridae. They are enveloped, non-segmented viruses, with negative-sense single stranded genomes. Respiratory syncytial virus (hRSV) is the best characterized agent viral of this group, associated with respiratory diseases in lower respiratory tract. Recently, a new human pathogen belonging to the subfamily Pneumovirinae was identified, the human metapneumovirus (hMPV), which is structurally similar to the hRSV, in genomic organization, viral structure, antigenicity and clinical symptoms. The subfamily Pneumovirinae contains two genera: genus Pneumovirus contains hRSV, the bovine (bRSV), as well as the ovine and caprine respiratory syncytial virus and pneumonia virus of mice, the second genus Metapneumovirus, consists of avian metapneumovirus (aMPV) and human metapneumovirus (hMPV). In this work, we present a brief narrative review of the literature on important aspects of the biology, epidemiology and clinical manifestations of infections by two respiratory viruses. |
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Clinical and Biomedical Research |
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Human Respiratory Syncytial Virus and Human MetapneumovirusVírus Respiratório Sincicial Humano e Metapneumovírus HumanoVírus respiratório sincicial humanoMetapneumovírus humanoinfecções respiratóriasVírushuman respiratory syncytial virushuman metapneumovirushMPVrespiratory infectionsThe human respiratory syncytial virus (hRSV) and the human metapneumovírus (hMPV) are main etiological agents of acute respiratory infections (ARI). The ARI is an important cause of childhood morbidity and mortality worldwide. hRSV and hMPV are members of the Paramyxoviridae. They are enveloped, non-segmented viruses, with negative-sense single stranded genomes. Respiratory syncytial virus (hRSV) is the best characterized agent viral of this group, associated with respiratory diseases in lower respiratory tract. Recently, a new human pathogen belonging to the subfamily Pneumovirinae was identified, the human metapneumovirus (hMPV), which is structurally similar to the hRSV, in genomic organization, viral structure, antigenicity and clinical symptoms. The subfamily Pneumovirinae contains two genera: genus Pneumovirus contains hRSV, the bovine (bRSV), as well as the ovine and caprine respiratory syncytial virus and pneumonia virus of mice, the second genus Metapneumovirus, consists of avian metapneumovirus (aMPV) and human metapneumovirus (hMPV). In this work, we present a brief narrative review of the literature on important aspects of the biology, epidemiology and clinical manifestations of infections by two respiratory viruses.O Vírus respiratório sincicial humano (hRSV - human respiratory syncytial virus) e o Metapneumovírus humano (hMPV - human metapneumovirus) são os principais agentes etiológicos identificados nas infecções respiratórias agudas (IRAs). As IRAs representam importante causa de morbidade e mortalidade em crianças no mundo todo. hRSV e hMPV são membros da família Paramyxoviridae. São vírus envelopados, não-segmentados dotados de genoma de RNA de fita simples com sentido negativo. O hRSV é o agente viral melhor caracterizado neste grupo, associado à doença do trato respiratório inferior. Recentemente foi identificado um novo patógeno humano pertencente à subfamília Pneumovirinae, o hMPV, o qual possui similaridades com o hRSV, na sua organização genômica, estrutura viral, antigenicidade e sintomas clínicos. A subfamília Pneumovirinae contém dois gêneros: gênero Pneumovirus que contêm o hRSV, o RSV bovino (bRSV - bovine RSV), bem como os RSV ovino, caprino e o vírus da pneumonia murina, o segundo gênero Metapneumovirus que consiste do MPV aviário (aMPV - avian MPV) e hMPV. Neste trabalho, apresentamos uma breve revisão narrativa da literatura sobre aspectos importantes da biologia, epidemiologia e manifestações clínicas das infecções por estes dois vírus respiratórios. HCPA/FAMED/UFRGS2009-08-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliados por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/8065Clinical & Biomedical Research; Vol. 29 No. 2 (2009): Revista HCPAClinical and Biomedical Research; v. 29 n. 2 (2009): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/8065/5760da Silva, Luciana Helena AntoniassiSpilki, Fernando RosadoRiccetto, Adriana Gut LopesBaracat, Emilio EliasArns, Clarice Weisinfo:eu-repo/semantics/openAccess2020-01-16T16:20:25Zoai:seer.ufrgs.br:article/8065Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2020-01-16T16:20:25Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.none.fl_str_mv |
Human Respiratory Syncytial Virus and Human Metapneumovirus Vírus Respiratório Sincicial Humano e Metapneumovírus Humano |
title |
Human Respiratory Syncytial Virus and Human Metapneumovirus |
spellingShingle |
Human Respiratory Syncytial Virus and Human Metapneumovirus da Silva, Luciana Helena Antoniassi Vírus respiratório sincicial humano Metapneumovírus humano infecções respiratórias Vírus human respiratory syncytial virus human metapneumovirus hMPV respiratory infections |
title_short |
Human Respiratory Syncytial Virus and Human Metapneumovirus |
title_full |
Human Respiratory Syncytial Virus and Human Metapneumovirus |
title_fullStr |
Human Respiratory Syncytial Virus and Human Metapneumovirus |
title_full_unstemmed |
Human Respiratory Syncytial Virus and Human Metapneumovirus |
title_sort |
Human Respiratory Syncytial Virus and Human Metapneumovirus |
author |
da Silva, Luciana Helena Antoniassi |
author_facet |
da Silva, Luciana Helena Antoniassi Spilki, Fernando Rosado Riccetto, Adriana Gut Lopes Baracat, Emilio Elias Arns, Clarice Weis |
author_role |
author |
author2 |
Spilki, Fernando Rosado Riccetto, Adriana Gut Lopes Baracat, Emilio Elias Arns, Clarice Weis |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
da Silva, Luciana Helena Antoniassi Spilki, Fernando Rosado Riccetto, Adriana Gut Lopes Baracat, Emilio Elias Arns, Clarice Weis |
dc.subject.por.fl_str_mv |
Vírus respiratório sincicial humano Metapneumovírus humano infecções respiratórias Vírus human respiratory syncytial virus human metapneumovirus hMPV respiratory infections |
topic |
Vírus respiratório sincicial humano Metapneumovírus humano infecções respiratórias Vírus human respiratory syncytial virus human metapneumovirus hMPV respiratory infections |
description |
The human respiratory syncytial virus (hRSV) and the human metapneumovírus (hMPV) are main etiological agents of acute respiratory infections (ARI). The ARI is an important cause of childhood morbidity and mortality worldwide. hRSV and hMPV are members of the Paramyxoviridae. They are enveloped, non-segmented viruses, with negative-sense single stranded genomes. Respiratory syncytial virus (hRSV) is the best characterized agent viral of this group, associated with respiratory diseases in lower respiratory tract. Recently, a new human pathogen belonging to the subfamily Pneumovirinae was identified, the human metapneumovirus (hMPV), which is structurally similar to the hRSV, in genomic organization, viral structure, antigenicity and clinical symptoms. The subfamily Pneumovirinae contains two genera: genus Pneumovirus contains hRSV, the bovine (bRSV), as well as the ovine and caprine respiratory syncytial virus and pneumonia virus of mice, the second genus Metapneumovirus, consists of avian metapneumovirus (aMPV) and human metapneumovirus (hMPV). In this work, we present a brief narrative review of the literature on important aspects of the biology, epidemiology and clinical manifestations of infections by two respiratory viruses. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-08-24 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article Avaliados por Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/8065 |
url |
https://seer.ufrgs.br/index.php/hcpa/article/view/8065 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/8065/5760 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
dc.source.none.fl_str_mv |
Clinical & Biomedical Research; Vol. 29 No. 2 (2009): Revista HCPA Clinical and Biomedical Research; v. 29 n. 2 (2009): Revista HCPA 2357-9730 reponame:Clinical and Biomedical Research instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Clinical and Biomedical Research |
collection |
Clinical and Biomedical Research |
repository.name.fl_str_mv |
Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
||cbr@hcpa.edu.br |
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1750135155465388032 |