Preoperative assessment of delayed hypersensitivity skin tests and lymphocyte count in patients with epidermoid esophageal carcinoma

• Autor(a) principal: R. Gurski, Richard
• Data de Publicação: 2022
• Outros Autores: Cauduro Schirmer, Carlos, Pereira da Rosa, André Ricardo, G. dos Santos, Wellington, D. Kruel, Cleber, Brentano, Loreno
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Clinical and Biomedical Research
• Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/124755

OBJECTIVE: Cutaneous tests for delayed hipersensivity have been used for differentiating preoperative immunologic status so as to determine nutritional performance. The aim of this study was to evaluate the immunologic status of patients with squamous cell carcinoma of the esophagus.PATIENTS AND METHODS: Delayed hipersensivity and lymphocytometry were preoperatively assessed in 45 patients with squamous cell carcinoma (cases) and90 patients with common surgical diseases (controls).RESULTS: Comparison of weight loss between the two groups showed that the case group was significantly more malnourished than the controls (P = 0.001). None of the cutaneous tests used (candidin, varidase, tricofitin, and tuberculin) showed statistical significance (P = NS) when the two groups were compared. There was statistical difference (P = 0.002) in lymphocytometry with a significant decrease of lymphocyte counts in the control group.CONCLUSIONS: The authors conclude that the cutaneous tests for delayed hipersensitivity were of little application for differentiating preoperative immunologicstatus to determine nutritional performance, while lymphocytometry seems to be a reliable test to evaluate cellular immunity in patients with squamous cell carcinoma. Lymphocytometry may be used as an additional test to assess malnutrition in these patients.