Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/221812 |
Resumo: | Parkinson's disease (PD) is a neurodegenerative disorder with significant motor disabilities and cognitive decline. Importantly, the imbalance of oxidative stress is related to PD physiopathology and progression. This study aimed to evaluate the impact of grape juice consumption associated with an aquatic exercise protocol on oxidative stress parameters and cognitive function in individuals with PD. The participants were randomized into two groups: grape juice group (GJG) and control group (CG) and were submitted to 4 weeks of an aquatic intervention (twice a week, approximately 60 minutes/session). The GJG also consumed 400 ml of grape juice per day (integral and conventional) during this period. Cognitive function was assessed by the Montreal Cognitive Assessment (MoCa) questionnaire. For the analysis of oxidative stress markers, specifically lipid oxidative damage (TBARS), proteins (Carbonil), acid uric and the activity of antioxidant enzymes (superoxide dismutase, glutathione peroxidase and catalase), blood collection were done before and after intervention. No changes were observed in cognitive function after intervention in both groups. Regarding biomarkers, a reduction of antioxidant enzymes, thiobarbituric acid reactive substances (TBARS) and uric acid was observed in both groups. However, only the GJG showed a significant reduction on protein oxidation levels after intervention. In conclusion, the consumption of grape juice associated with an aquatic exercise protocol might be consider an effective alternative to reduce the oxidative damage in PD, reinforcing the importance of this intervention in promoting beneficial impact in this population. |
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Oliveira, Grazielle S. dePinheiro, Gislaine S.Proença, Isabel Cristina TeixeiraBlembeel, Amanda StolzenbergCasal, Marcela ZimmermannPochmann, DanielaPeyré-Tartaruga, Leonardo AlexandreMartinez, Flavia GomesAraújo, Alex Sander da RosaElsner, Viviane RostirolaDani, Caroline2021-06-02T04:33:29Z20212405-8440http://hdl.handle.net/10183/221812001126505Parkinson's disease (PD) is a neurodegenerative disorder with significant motor disabilities and cognitive decline. Importantly, the imbalance of oxidative stress is related to PD physiopathology and progression. This study aimed to evaluate the impact of grape juice consumption associated with an aquatic exercise protocol on oxidative stress parameters and cognitive function in individuals with PD. The participants were randomized into two groups: grape juice group (GJG) and control group (CG) and were submitted to 4 weeks of an aquatic intervention (twice a week, approximately 60 minutes/session). The GJG also consumed 400 ml of grape juice per day (integral and conventional) during this period. Cognitive function was assessed by the Montreal Cognitive Assessment (MoCa) questionnaire. For the analysis of oxidative stress markers, specifically lipid oxidative damage (TBARS), proteins (Carbonil), acid uric and the activity of antioxidant enzymes (superoxide dismutase, glutathione peroxidase and catalase), blood collection were done before and after intervention. No changes were observed in cognitive function after intervention in both groups. Regarding biomarkers, a reduction of antioxidant enzymes, thiobarbituric acid reactive substances (TBARS) and uric acid was observed in both groups. However, only the GJG showed a significant reduction on protein oxidation levels after intervention. In conclusion, the consumption of grape juice associated with an aquatic exercise protocol might be consider an effective alternative to reduce the oxidative damage in PD, reinforcing the importance of this intervention in promoting beneficial impact in this population.application/pdfengHeliyon. London. Vol. 7, no. 2 (Feb. 2021), e06185, 9 p.Doença de ParkinsonEstresse oxidativoNataçãoSuco de uvaGrape juiceAquatic exerciseOxidative stressCognitionAquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention studyEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001126505.pdf.txt001126505.pdf.txtExtracted Texttext/plain52635http://www.lume.ufrgs.br/bitstream/10183/221812/2/001126505.pdf.txtc94ac55a8ef50e7e88b5cf33d606fa58MD52ORIGINAL001126505.pdfTexto completo (inglês)application/pdf1045439http://www.lume.ufrgs.br/bitstream/10183/221812/1/001126505.pdf9f6940fe17daf12ce2807df0cc4c7be9MD5110183/2218122021-06-13 04:31:57.146599oai:www.lume.ufrgs.br:10183/221812Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-06-13T07:31:57Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study |
title |
Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study |
spellingShingle |
Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study Oliveira, Grazielle S. de Doença de Parkinson Estresse oxidativo Natação Suco de uva Grape juice Aquatic exercise Oxidative stress Cognition |
title_short |
Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study |
title_full |
Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study |
title_fullStr |
Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study |
title_full_unstemmed |
Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study |
title_sort |
Aquatic exercise associated or not with grape juice consumption-modulated oxidative parameters in Parkinson disease patients : a randomized intervention study |
author |
Oliveira, Grazielle S. de |
author_facet |
Oliveira, Grazielle S. de Pinheiro, Gislaine S. Proença, Isabel Cristina Teixeira Blembeel, Amanda Stolzenberg Casal, Marcela Zimmermann Pochmann, Daniela Peyré-Tartaruga, Leonardo Alexandre Martinez, Flavia Gomes Araújo, Alex Sander da Rosa Elsner, Viviane Rostirola Dani, Caroline |
author_role |
author |
author2 |
Pinheiro, Gislaine S. Proença, Isabel Cristina Teixeira Blembeel, Amanda Stolzenberg Casal, Marcela Zimmermann Pochmann, Daniela Peyré-Tartaruga, Leonardo Alexandre Martinez, Flavia Gomes Araújo, Alex Sander da Rosa Elsner, Viviane Rostirola Dani, Caroline |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Grazielle S. de Pinheiro, Gislaine S. Proença, Isabel Cristina Teixeira Blembeel, Amanda Stolzenberg Casal, Marcela Zimmermann Pochmann, Daniela Peyré-Tartaruga, Leonardo Alexandre Martinez, Flavia Gomes Araújo, Alex Sander da Rosa Elsner, Viviane Rostirola Dani, Caroline |
dc.subject.por.fl_str_mv |
Doença de Parkinson Estresse oxidativo Natação Suco de uva |
topic |
Doença de Parkinson Estresse oxidativo Natação Suco de uva Grape juice Aquatic exercise Oxidative stress Cognition |
dc.subject.eng.fl_str_mv |
Grape juice Aquatic exercise Oxidative stress Cognition |
description |
Parkinson's disease (PD) is a neurodegenerative disorder with significant motor disabilities and cognitive decline. Importantly, the imbalance of oxidative stress is related to PD physiopathology and progression. This study aimed to evaluate the impact of grape juice consumption associated with an aquatic exercise protocol on oxidative stress parameters and cognitive function in individuals with PD. The participants were randomized into two groups: grape juice group (GJG) and control group (CG) and were submitted to 4 weeks of an aquatic intervention (twice a week, approximately 60 minutes/session). The GJG also consumed 400 ml of grape juice per day (integral and conventional) during this period. Cognitive function was assessed by the Montreal Cognitive Assessment (MoCa) questionnaire. For the analysis of oxidative stress markers, specifically lipid oxidative damage (TBARS), proteins (Carbonil), acid uric and the activity of antioxidant enzymes (superoxide dismutase, glutathione peroxidase and catalase), blood collection were done before and after intervention. No changes were observed in cognitive function after intervention in both groups. Regarding biomarkers, a reduction of antioxidant enzymes, thiobarbituric acid reactive substances (TBARS) and uric acid was observed in both groups. However, only the GJG showed a significant reduction on protein oxidation levels after intervention. In conclusion, the consumption of grape juice associated with an aquatic exercise protocol might be consider an effective alternative to reduce the oxidative damage in PD, reinforcing the importance of this intervention in promoting beneficial impact in this population. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-06-02T04:33:29Z |
dc.date.issued.fl_str_mv |
2021 |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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publishedVersion |
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http://hdl.handle.net/10183/221812 |
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2405-8440 |
dc.identifier.nrb.pt_BR.fl_str_mv |
001126505 |
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http://hdl.handle.net/10183/221812 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Heliyon. London. Vol. 7, no. 2 (Feb. 2021), e06185, 9 p. |
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