Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/164346 |
Resumo: | The aim of this study was to assess the accuracy of clinical diagnosis for lip lesions based on sensitivity and specificity. The retrospective analysis focused on the detection of lesions caused by potentially malignant disorders (PMDs) and malignant lesions (n = 1195). All cases were classified as benign, PMD, and malignant lesions. Concordance between diagnoses based on clinical examination and those based on histopathological analysis was assessed, and accuracy for the identification of PMD and malignant lesions was calculated. Histopathological analysis revealed 44 lesion types; PMD and malignant lesions comprised 8.3% of all cases. Compared with histopathological analysis, clinical examination showed 97.4% accuracy for the identification of non-malignant and potentially malignant/malignant cases. Degrees of specific sensitivity ranged from 34% to 77% for different lesions, and were highest for autoimmune (77%) and reactive (72%) lesions. Positive and negative predictive values for the identification of PMD and malignant lesions were 81.9% and 98.9%, respectively. Clinical examination showed a high degree of accuracy for the detection of PMD and malignant lip lesions, indicating good reliability. |
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Curra, MarinaSilva, Gabriela Salvadori daJunges, RogerSant'Ana Filho, ManoelHugo, Fernando NevesMartins, Manoela Domingues2017-07-25T02:30:51Z20161806-8324http://hdl.handle.net/10183/164346001023131The aim of this study was to assess the accuracy of clinical diagnosis for lip lesions based on sensitivity and specificity. The retrospective analysis focused on the detection of lesions caused by potentially malignant disorders (PMDs) and malignant lesions (n = 1195). All cases were classified as benign, PMD, and malignant lesions. Concordance between diagnoses based on clinical examination and those based on histopathological analysis was assessed, and accuracy for the identification of PMD and malignant lesions was calculated. Histopathological analysis revealed 44 lesion types; PMD and malignant lesions comprised 8.3% of all cases. Compared with histopathological analysis, clinical examination showed 97.4% accuracy for the identification of non-malignant and potentially malignant/malignant cases. Degrees of specific sensitivity ranged from 34% to 77% for different lesions, and were highest for autoimmune (77%) and reactive (72%) lesions. Positive and negative predictive values for the identification of PMD and malignant lesions were 81.9% and 98.9%, respectively. Clinical examination showed a high degree of accuracy for the detection of PMD and malignant lip lesions, indicating good reliability.application/pdfengBrazilian oral research. São Paulo. Vol. 30, no. 1 (2016), p. e135, 1-8Patologia bucalLabioNeoplasias bucaisLip diseaseClinical diagnosisNeoplasmAccuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesionsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL001023131.pdf001023131.pdfTexto completo (inglês)application/pdf287758http://www.lume.ufrgs.br/bitstream/10183/164346/1/001023131.pdfb96b83bd48e1c6feca0c1896acc49cc9MD51TEXT001023131.pdf.txt001023131.pdf.txtExtracted Texttext/plain34380http://www.lume.ufrgs.br/bitstream/10183/164346/2/001023131.pdf.txtf288e1a7d3c5de51020c955d96e93346MD52THUMBNAIL001023131.pdf.jpg001023131.pdf.jpgGenerated Thumbnailimage/jpeg2045http://www.lume.ufrgs.br/bitstream/10183/164346/3/001023131.pdf.jpg78b4a91a241649e999a5928cd704625dMD5310183/1643462018-10-15 09:33:27.184oai:www.lume.ufrgs.br:10183/164346Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-15T12:33:27Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions |
title |
Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions |
spellingShingle |
Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions Curra, Marina Patologia bucal Labio Neoplasias bucais Lip disease Clinical diagnosis Neoplasm |
title_short |
Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions |
title_full |
Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions |
title_fullStr |
Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions |
title_full_unstemmed |
Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions |
title_sort |
Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions |
author |
Curra, Marina |
author_facet |
Curra, Marina Silva, Gabriela Salvadori da Junges, Roger Sant'Ana Filho, Manoel Hugo, Fernando Neves Martins, Manoela Domingues |
author_role |
author |
author2 |
Silva, Gabriela Salvadori da Junges, Roger Sant'Ana Filho, Manoel Hugo, Fernando Neves Martins, Manoela Domingues |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Curra, Marina Silva, Gabriela Salvadori da Junges, Roger Sant'Ana Filho, Manoel Hugo, Fernando Neves Martins, Manoela Domingues |
dc.subject.por.fl_str_mv |
Patologia bucal Labio Neoplasias bucais |
topic |
Patologia bucal Labio Neoplasias bucais Lip disease Clinical diagnosis Neoplasm |
dc.subject.eng.fl_str_mv |
Lip disease Clinical diagnosis Neoplasm |
description |
The aim of this study was to assess the accuracy of clinical diagnosis for lip lesions based on sensitivity and specificity. The retrospective analysis focused on the detection of lesions caused by potentially malignant disorders (PMDs) and malignant lesions (n = 1195). All cases were classified as benign, PMD, and malignant lesions. Concordance between diagnoses based on clinical examination and those based on histopathological analysis was assessed, and accuracy for the identification of PMD and malignant lesions was calculated. Histopathological analysis revealed 44 lesion types; PMD and malignant lesions comprised 8.3% of all cases. Compared with histopathological analysis, clinical examination showed 97.4% accuracy for the identification of non-malignant and potentially malignant/malignant cases. Degrees of specific sensitivity ranged from 34% to 77% for different lesions, and were highest for autoimmune (77%) and reactive (72%) lesions. Positive and negative predictive values for the identification of PMD and malignant lesions were 81.9% and 98.9%, respectively. Clinical examination showed a high degree of accuracy for the detection of PMD and malignant lip lesions, indicating good reliability. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2017-07-25T02:30:51Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/other |
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001023131 |
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eng |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Brazilian oral research. São Paulo. Vol. 30, no. 1 (2016), p. e135, 1-8 |
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