Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/267700 |
Resumo: | The objective was to assess the antioxidant eff ect of melatonin (MLT) on liver and lung tissues of animals with bile duct ligation (BDL)-induced hepato-pulmonary syndrome (HPS). A model of BDL-induced biliary cirrhosis was used in male Wistar rats. Results suggest that MLT has an antioxidant eff ect on liver and lung tissues in animals with BDL-induced HPS by higher activity of antioxidant enzymes in the group HPS treated with MLT and the histological analysis of lung parenchyma showing decreased damage in this same group, including other analysis described below. |
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Dal Bosco, AdrianeColares, Josieli RaskopfBona, Silvia ReginaAndrade, Lívia BarbozaForgiarini Júnior, Luiz AlbertoBueno, Aline FelícioDias, Alexandre SimõesMarroni, Norma Anair Possa2023-11-28T03:22:38Z20212639-9954http://hdl.handle.net/10183/267700001175429The objective was to assess the antioxidant eff ect of melatonin (MLT) on liver and lung tissues of animals with bile duct ligation (BDL)-induced hepato-pulmonary syndrome (HPS). A model of BDL-induced biliary cirrhosis was used in male Wistar rats. Results suggest that MLT has an antioxidant eff ect on liver and lung tissues in animals with BDL-induced HPS by higher activity of antioxidant enzymes in the group HPS treated with MLT and the histological analysis of lung parenchyma showing decreased damage in this same group, including other analysis described below.application/pdfengJournal of Pulmonology and Respiratory Research. East Windsor. Vol. 5, (Jan. 2021), p. 097-105.MelatoninaAntioxidantesSíndrome hepatopulmonarEffects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndromeEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001175429.pdf.txt001175429.pdf.txtExtracted Texttext/plain39680http://www.lume.ufrgs.br/bitstream/10183/267700/2/001175429.pdf.txt62ccf7c401efd2674d408d46ed83682bMD52ORIGINAL001175429.pdfTexto completo (inglês)application/pdf325016http://www.lume.ufrgs.br/bitstream/10183/267700/1/001175429.pdf65fb01e9cef42aa29f1b9193a5b49495MD5110183/2677002023-11-29 04:24:31.460565oai:www.lume.ufrgs.br:10183/267700Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-11-29T06:24:31Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome |
title |
Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome |
spellingShingle |
Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome Dal Bosco, Adriane Melatonina Antioxidantes Síndrome hepatopulmonar |
title_short |
Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome |
title_full |
Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome |
title_fullStr |
Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome |
title_full_unstemmed |
Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome |
title_sort |
Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome |
author |
Dal Bosco, Adriane |
author_facet |
Dal Bosco, Adriane Colares, Josieli Raskopf Bona, Silvia Regina Andrade, Lívia Barboza Forgiarini Júnior, Luiz Alberto Bueno, Aline Felício Dias, Alexandre Simões Marroni, Norma Anair Possa |
author_role |
author |
author2 |
Colares, Josieli Raskopf Bona, Silvia Regina Andrade, Lívia Barboza Forgiarini Júnior, Luiz Alberto Bueno, Aline Felício Dias, Alexandre Simões Marroni, Norma Anair Possa |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Dal Bosco, Adriane Colares, Josieli Raskopf Bona, Silvia Regina Andrade, Lívia Barboza Forgiarini Júnior, Luiz Alberto Bueno, Aline Felício Dias, Alexandre Simões Marroni, Norma Anair Possa |
dc.subject.por.fl_str_mv |
Melatonina Antioxidantes Síndrome hepatopulmonar |
topic |
Melatonina Antioxidantes Síndrome hepatopulmonar |
description |
The objective was to assess the antioxidant eff ect of melatonin (MLT) on liver and lung tissues of animals with bile duct ligation (BDL)-induced hepato-pulmonary syndrome (HPS). A model of BDL-induced biliary cirrhosis was used in male Wistar rats. Results suggest that MLT has an antioxidant eff ect on liver and lung tissues in animals with BDL-induced HPS by higher activity of antioxidant enzymes in the group HPS treated with MLT and the histological analysis of lung parenchyma showing decreased damage in this same group, including other analysis described below. |
publishDate |
2021 |
dc.date.issued.fl_str_mv |
2021 |
dc.date.accessioned.fl_str_mv |
2023-11-28T03:22:38Z |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/267700 |
dc.identifier.issn.pt_BR.fl_str_mv |
2639-9954 |
dc.identifier.nrb.pt_BR.fl_str_mv |
001175429 |
identifier_str_mv |
2639-9954 001175429 |
url |
http://hdl.handle.net/10183/267700 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Journal of Pulmonology and Respiratory Research. East Windsor. Vol. 5, (Jan. 2021), p. 097-105. |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
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reponame:Repositório Institucional da UFRGS instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
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UFRGS |
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Repositório Institucional da UFRGS |
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Repositório Institucional da UFRGS |
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