Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome

Detalhes bibliográficos
Autor(a) principal: Dal Bosco, Adriane
Data de Publicação: 2021
Outros Autores: Colares, Josieli Raskopf, Bona, Silvia Regina, Andrade, Lívia Barboza, Forgiarini Júnior, Luiz Alberto, Bueno, Aline Felício, Dias, Alexandre Simões, Marroni, Norma Anair Possa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/267700
Resumo: The objective was to assess the antioxidant eff ect of melatonin (MLT) on liver and lung tissues of animals with bile duct ligation (BDL)-induced hepato-pulmonary syndrome (HPS). A model of BDL-induced biliary cirrhosis was used in male Wistar rats. Results suggest that MLT has an antioxidant eff ect on liver and lung tissues in animals with BDL-induced HPS by higher activity of antioxidant enzymes in the group HPS treated with MLT and the histological analysis of lung parenchyma showing decreased damage in this same group, including other analysis described below.
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spelling Dal Bosco, AdrianeColares, Josieli RaskopfBona, Silvia ReginaAndrade, Lívia BarbozaForgiarini Júnior, Luiz AlbertoBueno, Aline FelícioDias, Alexandre SimõesMarroni, Norma Anair Possa2023-11-28T03:22:38Z20212639-9954http://hdl.handle.net/10183/267700001175429The objective was to assess the antioxidant eff ect of melatonin (MLT) on liver and lung tissues of animals with bile duct ligation (BDL)-induced hepato-pulmonary syndrome (HPS). A model of BDL-induced biliary cirrhosis was used in male Wistar rats. Results suggest that MLT has an antioxidant eff ect on liver and lung tissues in animals with BDL-induced HPS by higher activity of antioxidant enzymes in the group HPS treated with MLT and the histological analysis of lung parenchyma showing decreased damage in this same group, including other analysis described below.application/pdfengJournal of Pulmonology and Respiratory Research. East Windsor. Vol. 5, (Jan. 2021), p. 097-105.MelatoninaAntioxidantesSíndrome hepatopulmonarEffects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndromeEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001175429.pdf.txt001175429.pdf.txtExtracted Texttext/plain39680http://www.lume.ufrgs.br/bitstream/10183/267700/2/001175429.pdf.txt62ccf7c401efd2674d408d46ed83682bMD52ORIGINAL001175429.pdfTexto completo (inglês)application/pdf325016http://www.lume.ufrgs.br/bitstream/10183/267700/1/001175429.pdf65fb01e9cef42aa29f1b9193a5b49495MD5110183/2677002023-11-29 04:24:31.460565oai:www.lume.ufrgs.br:10183/267700Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-11-29T06:24:31Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
title Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
spellingShingle Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
Dal Bosco, Adriane
Melatonina
Antioxidantes
Síndrome hepatopulmonar
title_short Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
title_full Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
title_fullStr Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
title_full_unstemmed Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
title_sort Effects of melatonin on liver and lung tissues of animals with bile duct ligation-induced hepatopulmonary syndrome
author Dal Bosco, Adriane
author_facet Dal Bosco, Adriane
Colares, Josieli Raskopf
Bona, Silvia Regina
Andrade, Lívia Barboza
Forgiarini Júnior, Luiz Alberto
Bueno, Aline Felício
Dias, Alexandre Simões
Marroni, Norma Anair Possa
author_role author
author2 Colares, Josieli Raskopf
Bona, Silvia Regina
Andrade, Lívia Barboza
Forgiarini Júnior, Luiz Alberto
Bueno, Aline Felício
Dias, Alexandre Simões
Marroni, Norma Anair Possa
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Dal Bosco, Adriane
Colares, Josieli Raskopf
Bona, Silvia Regina
Andrade, Lívia Barboza
Forgiarini Júnior, Luiz Alberto
Bueno, Aline Felício
Dias, Alexandre Simões
Marroni, Norma Anair Possa
dc.subject.por.fl_str_mv Melatonina
Antioxidantes
Síndrome hepatopulmonar
topic Melatonina
Antioxidantes
Síndrome hepatopulmonar
description The objective was to assess the antioxidant eff ect of melatonin (MLT) on liver and lung tissues of animals with bile duct ligation (BDL)-induced hepato-pulmonary syndrome (HPS). A model of BDL-induced biliary cirrhosis was used in male Wistar rats. Results suggest that MLT has an antioxidant eff ect on liver and lung tissues in animals with BDL-induced HPS by higher activity of antioxidant enzymes in the group HPS treated with MLT and the histological analysis of lung parenchyma showing decreased damage in this same group, including other analysis described below.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2023-11-28T03:22:38Z
dc.type.driver.fl_str_mv Estrangeiro
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/267700
dc.identifier.issn.pt_BR.fl_str_mv 2639-9954
dc.identifier.nrb.pt_BR.fl_str_mv 001175429
identifier_str_mv 2639-9954
001175429
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dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.pt_BR.fl_str_mv Journal of Pulmonology and Respiratory Research. East Windsor. Vol. 5, (Jan. 2021), p. 097-105.
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