Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/271782 |
Resumo: | Açaí (Euterpe oleracea Mart.) juice is rich in phenolic compounds with high antioxidant capacity. It has been observed that the use of antioxidants may be an additional strategy to nonsurgical periodontal therapy as well as to prevent alveolar bone loss. Thus, the objective of this study was to investigate the effects of açaí supplementation on experimental periodontitis in rats. Twenty male Rattus norvegicus (Wistar) rats were assigned into control, açaí, experimental periodontitis, and experimental periodontitis with açaí supplementation groups. Periodontitis was induced by placing ligatures around the lower first molars. Animals in the açaí groups received 0.01 mL/g of clarified açaí juice for 14 days by intragastric gavage. At the end of the experimental period, blood was collected to assess the reduced glutathione (GSH), Trolox equivalent antioxidant capacity (TEAC), and lipid peroxidation (TBARS) levels. Moreover, hemimandibles were analyzed by micro-computed tomography (micro-CT) for alveolar bone loss and bone quality. Açaí supplementation increased blood total antioxidant capacity and decreased lipid peroxidation. It also reduced alveolar bone loss when compared to the experimental periodontitis group. Moreover, clarified açaí per se modulated the oxidative biochemistry and bone microstructure. Thus, açaí may be considered a viable alternative for managing periodontal oxidative stress and preventing alveolar bone loss |
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Santos, Vinicius Ruan NevesFrazão, Deborah RibeiroFerreira, Railson de OliveiraMendes, Paulo Fernando SantosSilva, Daiane Claydes Baia daSouza-Monteiro, DeiwesonBittencourt, Leonardo de OliveiraMoura, João Daniel Mendonça deSantos Junior, José Messias Perdigão dosTeixeira, Bruno José BritoVarela, Everton Luiz PompeuBalbinot, Gabriela de SouzaPercário, SandroRogez, Herve Louis GhislainRösing, Cassiano KuchenbeckerCollares, Fabrício MezzomoLima, Rafael Rodrigues2024-02-09T05:07:40Z20232076-3921http://hdl.handle.net/10183/271782001194681Açaí (Euterpe oleracea Mart.) juice is rich in phenolic compounds with high antioxidant capacity. It has been observed that the use of antioxidants may be an additional strategy to nonsurgical periodontal therapy as well as to prevent alveolar bone loss. Thus, the objective of this study was to investigate the effects of açaí supplementation on experimental periodontitis in rats. Twenty male Rattus norvegicus (Wistar) rats were assigned into control, açaí, experimental periodontitis, and experimental periodontitis with açaí supplementation groups. Periodontitis was induced by placing ligatures around the lower first molars. Animals in the açaí groups received 0.01 mL/g of clarified açaí juice for 14 days by intragastric gavage. At the end of the experimental period, blood was collected to assess the reduced glutathione (GSH), Trolox equivalent antioxidant capacity (TEAC), and lipid peroxidation (TBARS) levels. Moreover, hemimandibles were analyzed by micro-computed tomography (micro-CT) for alveolar bone loss and bone quality. Açaí supplementation increased blood total antioxidant capacity and decreased lipid peroxidation. It also reduced alveolar bone loss when compared to the experimental periodontitis group. Moreover, clarified açaí per se modulated the oxidative biochemistry and bone microstructure. Thus, açaí may be considered a viable alternative for managing periodontal oxidative stress and preventing alveolar bone lossapplication/pdfengAntioxidants. Basel. Vol. 11, (2022), p. 1 - 13PeriodontiteAntioxidantesEuterpePeriodontitisAntioxidantsAçaíEuterpe oleraceaAçaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in ratsEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001194681.pdf.txt001194681.pdf.txtExtracted Texttext/plain57584http://www.lume.ufrgs.br/bitstream/10183/271782/2/001194681.pdf.txtff73e44ef2ed151b763d44f6e149a2e6MD52ORIGINAL001194681.pdfTexto completo (inglês)application/pdf2408917http://www.lume.ufrgs.br/bitstream/10183/271782/1/001194681.pdf9e78bd9137a7e6d833310cbc8acdd231MD5110183/2717822024-02-10 06:08:34.979865oai:www.lume.ufrgs.br:10183/271782Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2024-02-10T08:08:34Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats |
title |
Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats |
spellingShingle |
Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats Santos, Vinicius Ruan Neves Periodontite Antioxidantes Euterpe Periodontitis Antioxidants Açaí Euterpe oleracea |
title_short |
Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats |
title_full |
Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats |
title_fullStr |
Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats |
title_full_unstemmed |
Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats |
title_sort |
Açaí (Euterpe oleracea Mart.) attenuates oxidative stress and alveolar bone damage in experimental periodontitis in rats |
author |
Santos, Vinicius Ruan Neves |
author_facet |
Santos, Vinicius Ruan Neves Frazão, Deborah Ribeiro Ferreira, Railson de Oliveira Mendes, Paulo Fernando Santos Silva, Daiane Claydes Baia da Souza-Monteiro, Deiweson Bittencourt, Leonardo de Oliveira Moura, João Daniel Mendonça de Santos Junior, José Messias Perdigão dos Teixeira, Bruno José Brito Varela, Everton Luiz Pompeu Balbinot, Gabriela de Souza Percário, Sandro Rogez, Herve Louis Ghislain Rösing, Cassiano Kuchenbecker Collares, Fabrício Mezzomo Lima, Rafael Rodrigues |
author_role |
author |
author2 |
Frazão, Deborah Ribeiro Ferreira, Railson de Oliveira Mendes, Paulo Fernando Santos Silva, Daiane Claydes Baia da Souza-Monteiro, Deiweson Bittencourt, Leonardo de Oliveira Moura, João Daniel Mendonça de Santos Junior, José Messias Perdigão dos Teixeira, Bruno José Brito Varela, Everton Luiz Pompeu Balbinot, Gabriela de Souza Percário, Sandro Rogez, Herve Louis Ghislain Rösing, Cassiano Kuchenbecker Collares, Fabrício Mezzomo Lima, Rafael Rodrigues |
author2_role |
author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Santos, Vinicius Ruan Neves Frazão, Deborah Ribeiro Ferreira, Railson de Oliveira Mendes, Paulo Fernando Santos Silva, Daiane Claydes Baia da Souza-Monteiro, Deiweson Bittencourt, Leonardo de Oliveira Moura, João Daniel Mendonça de Santos Junior, José Messias Perdigão dos Teixeira, Bruno José Brito Varela, Everton Luiz Pompeu Balbinot, Gabriela de Souza Percário, Sandro Rogez, Herve Louis Ghislain Rösing, Cassiano Kuchenbecker Collares, Fabrício Mezzomo Lima, Rafael Rodrigues |
dc.subject.por.fl_str_mv |
Periodontite Antioxidantes Euterpe |
topic |
Periodontite Antioxidantes Euterpe Periodontitis Antioxidants Açaí Euterpe oleracea |
dc.subject.eng.fl_str_mv |
Periodontitis Antioxidants Açaí Euterpe oleracea |
description |
Açaí (Euterpe oleracea Mart.) juice is rich in phenolic compounds with high antioxidant capacity. It has been observed that the use of antioxidants may be an additional strategy to nonsurgical periodontal therapy as well as to prevent alveolar bone loss. Thus, the objective of this study was to investigate the effects of açaí supplementation on experimental periodontitis in rats. Twenty male Rattus norvegicus (Wistar) rats were assigned into control, açaí, experimental periodontitis, and experimental periodontitis with açaí supplementation groups. Periodontitis was induced by placing ligatures around the lower first molars. Animals in the açaí groups received 0.01 mL/g of clarified açaí juice for 14 days by intragastric gavage. At the end of the experimental period, blood was collected to assess the reduced glutathione (GSH), Trolox equivalent antioxidant capacity (TEAC), and lipid peroxidation (TBARS) levels. Moreover, hemimandibles were analyzed by micro-computed tomography (micro-CT) for alveolar bone loss and bone quality. Açaí supplementation increased blood total antioxidant capacity and decreased lipid peroxidation. It also reduced alveolar bone loss when compared to the experimental periodontitis group. Moreover, clarified açaí per se modulated the oxidative biochemistry and bone microstructure. Thus, açaí may be considered a viable alternative for managing periodontal oxidative stress and preventing alveolar bone loss |
publishDate |
2023 |
dc.date.issued.fl_str_mv |
2023 |
dc.date.accessioned.fl_str_mv |
2024-02-09T05:07:40Z |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/271782 |
dc.identifier.issn.pt_BR.fl_str_mv |
2076-3921 |
dc.identifier.nrb.pt_BR.fl_str_mv |
001194681 |
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2076-3921 001194681 |
url |
http://hdl.handle.net/10183/271782 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Antioxidants. Basel. Vol. 11, (2022), p. 1 - 13 |
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openAccess |
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