Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2024 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/274650 |
Resumo: | In the last decade, there has been a significant increase in the demand for small rodents such as hamsters, guinea pigs, rats, and mice to be kept as pets. Consequently, the veterinary care provided to these animals has also increased. The aim of this study was to describe gross, histopathological and immunohistochemical findings of 26 spontaneous neoplasms diagnosed in 25 pet rodents in Northeastern Brazil. A retrospective study was carried out from 2014 to 2022 in two veterinary diagnostic laboratories to identify cases of tumoriform lesions in these species. Hamsters represented the most frequent species in this study (60%, 15/25), followed by rats (28%, 7/25), guinea pigs (8%, 2/25), and mice (4%, 1/25), with a mean age of 17.63 months. The anatomical regions of the face/head and thoracic region were the most affected. The most affected tissues were the skin/subcutaneous/mucosal (65%, 15/26) and mammary gland (23%, 6/26). Eighteen different types of neoplasms were diagnosed, and T-cell lymphomas and mammary adenocarcinomas were the most diagnosed tumors, each corresponding to 12% (3/26) of the cases. Leiomyosarcoma, myxosarcoma and mammary adenocarcinoma metastases were also noted. Immunohistochemistry was essential for the diagnosis of certain malignant mesenchymal and round-cell neoplasms. Pet rodent neoplasms in Northeastern Brazil are common, especially in hamsters, and immunohistochemistry can be a useful tool for the definitive diagnosis of these tumors. |
id |
UFRGS-2_79809174d8f751d390786074844c934a |
---|---|
oai_identifier_str |
oai:www.lume.ufrgs.br:10183/274650 |
network_acronym_str |
UFRGS-2 |
network_name_str |
Repositório Institucional da UFRGS |
repository_id_str |
|
spelling |
Pereira, Raquel Mota de FreitasLima, Telma de SousaOliveira, Rafael Lima deCastillo Fonseca, Silvio MiguelWicpolt, Nathalia dos SantosFarias, Roberto Citelli deLucena, Ricardo Barbosa dePavarini, Saulo PetinattiAraújo, Jeann Leal deMendonça, Fábio Souza2024-04-12T06:19:27Z20240100-736Xhttp://hdl.handle.net/10183/274650001200261In the last decade, there has been a significant increase in the demand for small rodents such as hamsters, guinea pigs, rats, and mice to be kept as pets. Consequently, the veterinary care provided to these animals has also increased. The aim of this study was to describe gross, histopathological and immunohistochemical findings of 26 spontaneous neoplasms diagnosed in 25 pet rodents in Northeastern Brazil. A retrospective study was carried out from 2014 to 2022 in two veterinary diagnostic laboratories to identify cases of tumoriform lesions in these species. Hamsters represented the most frequent species in this study (60%, 15/25), followed by rats (28%, 7/25), guinea pigs (8%, 2/25), and mice (4%, 1/25), with a mean age of 17.63 months. The anatomical regions of the face/head and thoracic region were the most affected. The most affected tissues were the skin/subcutaneous/mucosal (65%, 15/26) and mammary gland (23%, 6/26). Eighteen different types of neoplasms were diagnosed, and T-cell lymphomas and mammary adenocarcinomas were the most diagnosed tumors, each corresponding to 12% (3/26) of the cases. Leiomyosarcoma, myxosarcoma and mammary adenocarcinoma metastases were also noted. Immunohistochemistry was essential for the diagnosis of certain malignant mesenchymal and round-cell neoplasms. Pet rodent neoplasms in Northeastern Brazil are common, especially in hamsters, and immunohistochemistry can be a useful tool for the definitive diagnosis of these tumors.application/pdfengPesquisa veterinária brasileira. Rio de Janeiro. Vol. 44 (2024), e07410, 14 p.NeoplasiasCamundongosHamsterPorquinho-da-ÍndiaRatosBrasil, Região NordesteHistopatologiaImunohistoquímicaTumorsMouseHamsterGuinea pigRatRodentiaHistopathologyImmunohistochemistryClinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazilinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001200261.pdf.txt001200261.pdf.txtExtracted Texttext/plain64615http://www.lume.ufrgs.br/bitstream/10183/274650/2/001200261.pdf.txt261f7d5c51b9a603e7a40e3b28f5f5c9MD52ORIGINAL001200261.pdfTexto completo (inglês)application/pdf7064264http://www.lume.ufrgs.br/bitstream/10183/274650/1/001200261.pdfcfae3ffa961dd3768ad078221c6ac599MD5110183/2746502024-04-13 06:45:37.162941oai:www.lume.ufrgs.br:10183/274650Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2024-04-13T09:45:37Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil |
title |
Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil |
spellingShingle |
Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil Pereira, Raquel Mota de Freitas Neoplasias Camundongos Hamster Porquinho-da-Índia Ratos Brasil, Região Nordeste Histopatologia Imunohistoquímica Tumors Mouse Hamster Guinea pig Rat Rodentia Histopathology Immunohistochemistry |
title_short |
Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil |
title_full |
Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil |
title_fullStr |
Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil |
title_full_unstemmed |
Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil |
title_sort |
Clinical, pathological and immunohistochemical characterization of spontaneous neoplasms in pet rodents in Northeastern Brazil |
author |
Pereira, Raquel Mota de Freitas |
author_facet |
Pereira, Raquel Mota de Freitas Lima, Telma de Sousa Oliveira, Rafael Lima de Castillo Fonseca, Silvio Miguel Wicpolt, Nathalia dos Santos Farias, Roberto Citelli de Lucena, Ricardo Barbosa de Pavarini, Saulo Petinatti Araújo, Jeann Leal de Mendonça, Fábio Souza |
author_role |
author |
author2 |
Lima, Telma de Sousa Oliveira, Rafael Lima de Castillo Fonseca, Silvio Miguel Wicpolt, Nathalia dos Santos Farias, Roberto Citelli de Lucena, Ricardo Barbosa de Pavarini, Saulo Petinatti Araújo, Jeann Leal de Mendonça, Fábio Souza |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Pereira, Raquel Mota de Freitas Lima, Telma de Sousa Oliveira, Rafael Lima de Castillo Fonseca, Silvio Miguel Wicpolt, Nathalia dos Santos Farias, Roberto Citelli de Lucena, Ricardo Barbosa de Pavarini, Saulo Petinatti Araújo, Jeann Leal de Mendonça, Fábio Souza |
dc.subject.por.fl_str_mv |
Neoplasias Camundongos Hamster Porquinho-da-Índia Ratos Brasil, Região Nordeste Histopatologia Imunohistoquímica |
topic |
Neoplasias Camundongos Hamster Porquinho-da-Índia Ratos Brasil, Região Nordeste Histopatologia Imunohistoquímica Tumors Mouse Hamster Guinea pig Rat Rodentia Histopathology Immunohistochemistry |
dc.subject.eng.fl_str_mv |
Tumors Mouse Hamster Guinea pig Rat Rodentia Histopathology Immunohistochemistry |
description |
In the last decade, there has been a significant increase in the demand for small rodents such as hamsters, guinea pigs, rats, and mice to be kept as pets. Consequently, the veterinary care provided to these animals has also increased. The aim of this study was to describe gross, histopathological and immunohistochemical findings of 26 spontaneous neoplasms diagnosed in 25 pet rodents in Northeastern Brazil. A retrospective study was carried out from 2014 to 2022 in two veterinary diagnostic laboratories to identify cases of tumoriform lesions in these species. Hamsters represented the most frequent species in this study (60%, 15/25), followed by rats (28%, 7/25), guinea pigs (8%, 2/25), and mice (4%, 1/25), with a mean age of 17.63 months. The anatomical regions of the face/head and thoracic region were the most affected. The most affected tissues were the skin/subcutaneous/mucosal (65%, 15/26) and mammary gland (23%, 6/26). Eighteen different types of neoplasms were diagnosed, and T-cell lymphomas and mammary adenocarcinomas were the most diagnosed tumors, each corresponding to 12% (3/26) of the cases. Leiomyosarcoma, myxosarcoma and mammary adenocarcinoma metastases were also noted. Immunohistochemistry was essential for the diagnosis of certain malignant mesenchymal and round-cell neoplasms. Pet rodent neoplasms in Northeastern Brazil are common, especially in hamsters, and immunohistochemistry can be a useful tool for the definitive diagnosis of these tumors. |
publishDate |
2024 |
dc.date.accessioned.fl_str_mv |
2024-04-12T06:19:27Z |
dc.date.issued.fl_str_mv |
2024 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/other |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/274650 |
dc.identifier.issn.pt_BR.fl_str_mv |
0100-736X |
dc.identifier.nrb.pt_BR.fl_str_mv |
001200261 |
identifier_str_mv |
0100-736X 001200261 |
url |
http://hdl.handle.net/10183/274650 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Pesquisa veterinária brasileira. Rio de Janeiro. Vol. 44 (2024), e07410, 14 p. |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFRGS instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Repositório Institucional da UFRGS |
collection |
Repositório Institucional da UFRGS |
bitstream.url.fl_str_mv |
http://www.lume.ufrgs.br/bitstream/10183/274650/2/001200261.pdf.txt http://www.lume.ufrgs.br/bitstream/10183/274650/1/001200261.pdf |
bitstream.checksum.fl_str_mv |
261f7d5c51b9a603e7a40e3b28f5f5c9 cfae3ffa961dd3768ad078221c6ac599 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
|
_version_ |
1801225115465154560 |