Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/61180 |
Resumo: | Intracanal medication in pulpectomy therapy is used between appointments with the Objective of reducing pain and inflammatory processes in pulp and periapical tissues. Propolis has been known as a natural antibiotic and has been subject of medical and dental research due to its therapeutic properties such as antibiotic, analgesic and anti- inflammatory effects. Objective: The aim was to carry out an in vivo evaluation of the periapical tissue response to propolis paste when used as an intracanal medication in the teeth of dogs after pulpectomy. Material and Methods: 72 dog’s incisors were selected for the experiment. After biomechanical preparation the root canal was filled with a corticosteroid-antibiotic preparation, experimental propolis paste, non-medicament (negative control) or non-pulpectomy at all (positive control). The medications were left inside the root canal for 7, 14 or 28 days. At the end of the experimental period histological sections were prepared and all laboratories processes for Harris hematoxylin and eosin staining was proceeded followed by the analysis using an optical microscope. Sections were classified according to a score representing the inflammatory events observed: the presence of polymorphonuclear neutrophils, polymorphonuclear eosinophils, lymphocytes and plasma cells, macrophages and/or giant cells, fibrous condensation and abscesses. Results: There were statistically significant differences between the tissue reactions caused by the two substances being tested, after different experimental periods, with the periapical tissue that was in contact with propolis paste exhibiting fewer inflammatory reactions in comparison to corticosteroid-antibiotic preparation. Conclusions: The low tissue responses from propolis paste suggest that this material could be considered as an option for root canal medication after pulpectomy. |
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Ramos, Isabela França de Almeida SantosBiz, Michelle TillmannPaulino, NiraldoScremin, AmarilisDella Bona, AlvaroBarletta, Fernando BrancoFigueiredo, Jose Antonio Poli de2012-11-21T01:50:46Z20121678-7757http://hdl.handle.net/10183/61180000856624Intracanal medication in pulpectomy therapy is used between appointments with the Objective of reducing pain and inflammatory processes in pulp and periapical tissues. Propolis has been known as a natural antibiotic and has been subject of medical and dental research due to its therapeutic properties such as antibiotic, analgesic and anti- inflammatory effects. Objective: The aim was to carry out an in vivo evaluation of the periapical tissue response to propolis paste when used as an intracanal medication in the teeth of dogs after pulpectomy. Material and Methods: 72 dog’s incisors were selected for the experiment. After biomechanical preparation the root canal was filled with a corticosteroid-antibiotic preparation, experimental propolis paste, non-medicament (negative control) or non-pulpectomy at all (positive control). The medications were left inside the root canal for 7, 14 or 28 days. At the end of the experimental period histological sections were prepared and all laboratories processes for Harris hematoxylin and eosin staining was proceeded followed by the analysis using an optical microscope. Sections were classified according to a score representing the inflammatory events observed: the presence of polymorphonuclear neutrophils, polymorphonuclear eosinophils, lymphocytes and plasma cells, macrophages and/or giant cells, fibrous condensation and abscesses. Results: There were statistically significant differences between the tissue reactions caused by the two substances being tested, after different experimental periods, with the periapical tissue that was in contact with propolis paste exhibiting fewer inflammatory reactions in comparison to corticosteroid-antibiotic preparation. Conclusions: The low tissue responses from propolis paste suggest that this material could be considered as an option for root canal medication after pulpectomy.application/pdfengJournal of applied oral science. Bauru. Vol. 20, no. 1 (Jan./Feb. 2012), p. 50-56EndodontiaPulpectomiaPolpa dentáriaEndodonticsPropolisPulpectomyDental pulp cavityHistopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo studyinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000856624.pdf000856624.pdfTexto completo (inglês)application/pdf1347035http://www.lume.ufrgs.br/bitstream/10183/61180/1/000856624.pdf21e3cd38fd72bd65456e8cce5453bb14MD51TEXT000856624.pdf.txt000856624.pdf.txtExtracted Texttext/plain31370http://www.lume.ufrgs.br/bitstream/10183/61180/2/000856624.pdf.txtd8706efe78dc7295c80194d0cf227a01MD52THUMBNAIL000856624.pdf.jpg000856624.pdf.jpgGenerated Thumbnailimage/jpeg1645http://www.lume.ufrgs.br/bitstream/10183/61180/3/000856624.pdf.jpgf623ab8cefec3ce95bfe429548a17cd9MD5310183/611802023-08-12 03:49:43.647418oai:www.lume.ufrgs.br:10183/61180Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-08-12T06:49:43Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study |
title |
Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study |
spellingShingle |
Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study Ramos, Isabela França de Almeida Santos Endodontia Pulpectomia Polpa dentária Endodontics Propolis Pulpectomy Dental pulp cavity |
title_short |
Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study |
title_full |
Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study |
title_fullStr |
Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study |
title_full_unstemmed |
Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study |
title_sort |
Histopathological analysis of corticosteroid-antibiotic preparation and propolis paste formulation as intracanal medication after pulpectomy : an in vivo study |
author |
Ramos, Isabela França de Almeida Santos |
author_facet |
Ramos, Isabela França de Almeida Santos Biz, Michelle Tillmann Paulino, Niraldo Scremin, Amarilis Della Bona, Alvaro Barletta, Fernando Branco Figueiredo, Jose Antonio Poli de |
author_role |
author |
author2 |
Biz, Michelle Tillmann Paulino, Niraldo Scremin, Amarilis Della Bona, Alvaro Barletta, Fernando Branco Figueiredo, Jose Antonio Poli de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Ramos, Isabela França de Almeida Santos Biz, Michelle Tillmann Paulino, Niraldo Scremin, Amarilis Della Bona, Alvaro Barletta, Fernando Branco Figueiredo, Jose Antonio Poli de |
dc.subject.por.fl_str_mv |
Endodontia Pulpectomia Polpa dentária |
topic |
Endodontia Pulpectomia Polpa dentária Endodontics Propolis Pulpectomy Dental pulp cavity |
dc.subject.eng.fl_str_mv |
Endodontics Propolis Pulpectomy Dental pulp cavity |
description |
Intracanal medication in pulpectomy therapy is used between appointments with the Objective of reducing pain and inflammatory processes in pulp and periapical tissues. Propolis has been known as a natural antibiotic and has been subject of medical and dental research due to its therapeutic properties such as antibiotic, analgesic and anti- inflammatory effects. Objective: The aim was to carry out an in vivo evaluation of the periapical tissue response to propolis paste when used as an intracanal medication in the teeth of dogs after pulpectomy. Material and Methods: 72 dog’s incisors were selected for the experiment. After biomechanical preparation the root canal was filled with a corticosteroid-antibiotic preparation, experimental propolis paste, non-medicament (negative control) or non-pulpectomy at all (positive control). The medications were left inside the root canal for 7, 14 or 28 days. At the end of the experimental period histological sections were prepared and all laboratories processes for Harris hematoxylin and eosin staining was proceeded followed by the analysis using an optical microscope. Sections were classified according to a score representing the inflammatory events observed: the presence of polymorphonuclear neutrophils, polymorphonuclear eosinophils, lymphocytes and plasma cells, macrophages and/or giant cells, fibrous condensation and abscesses. Results: There were statistically significant differences between the tissue reactions caused by the two substances being tested, after different experimental periods, with the periapical tissue that was in contact with propolis paste exhibiting fewer inflammatory reactions in comparison to corticosteroid-antibiotic preparation. Conclusions: The low tissue responses from propolis paste suggest that this material could be considered as an option for root canal medication after pulpectomy. |
publishDate |
2012 |
dc.date.accessioned.fl_str_mv |
2012-11-21T01:50:46Z |
dc.date.issued.fl_str_mv |
2012 |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/61180 |
dc.identifier.issn.pt_BR.fl_str_mv |
1678-7757 |
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000856624 |
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http://hdl.handle.net/10183/61180 |
dc.language.iso.fl_str_mv |
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language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Journal of applied oral science. Bauru. Vol. 20, no. 1 (Jan./Feb. 2012), p. 50-56 |
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openAccess |
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