Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning

Detalhes bibliográficos
Autor(a) principal: Braghirolli, Daikelly Iglesias
Data de Publicação: 2010
Tipo de documento: Trabalho de conclusão de curso
Idioma: por
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/26814
Resumo: The effect of sterilization using ethanol, ultraviolet radiation (UVR) and antibiotic solution in PLGA scaffolds produced by electrospinning was evaluated. The properties of nanofibers and on the cellular adhesion were analysed. All methods generated sterile scaffolds but led to some kind of damage. Ethanol and antibiotics caused changes in morphology and dimensions of scaffolds, which was not observed when using UVR. On the other hand, UVR caused a greater reduction of molecular weight which increased with exposure time. Nanofibres sterilized with antibiotics showed greater cellular adhesion than the others methods, demonstrating their potentiality as a method to sterilize PLGA nanofibers.
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spelling Braghirolli, Daikelly IglesiasPranke, Patricia Helena LucasSteffens, Daniela2010-11-23T04:19:25Z2010http://hdl.handle.net/10183/26814000758433The effect of sterilization using ethanol, ultraviolet radiation (UVR) and antibiotic solution in PLGA scaffolds produced by electrospinning was evaluated. The properties of nanofibers and on the cellular adhesion were analysed. All methods generated sterile scaffolds but led to some kind of damage. Ethanol and antibiotics caused changes in morphology and dimensions of scaffolds, which was not observed when using UVR. On the other hand, UVR caused a greater reduction of molecular weight which increased with exposure time. Nanofibres sterilized with antibiotics showed greater cellular adhesion than the others methods, demonstrating their potentiality as a method to sterilize PLGA nanofibers.application/pdfporEsterilizaçãoNanofibrasNanofibersElectrospinningTissue engineeringEfeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinningThe effect of different sterilization methods on PLGA nanofibers produced by electrospinning info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal do Rio Grande do SulFaculdade de FarmáciaPorto Alegre, BR-RS2010Farmáciagraduaçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000758433.pdf000758433.pdfTexto completoapplication/pdf1506042http://www.lume.ufrgs.br/bitstream/10183/26814/1/000758433.pdf82563b988acd282a03b294086a65927eMD51TEXT000758433.pdf.txt000758433.pdf.txtExtracted Texttext/plain49959http://www.lume.ufrgs.br/bitstream/10183/26814/2/000758433.pdf.txtc2dabefbe4f0aff9b71fe084ba027c3eMD52THUMBNAIL000758433.pdf.jpg000758433.pdf.jpgGenerated Thumbnailimage/jpeg1089http://www.lume.ufrgs.br/bitstream/10183/26814/3/000758433.pdf.jpga10367f760e0e94d0d19ffd0dbf3ef14MD5310183/268142018-10-18 07:38:03.425oai:www.lume.ufrgs.br:10183/26814Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-18T10:38:03Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
dc.title.alternative.en.fl_str_mv The effect of different sterilization methods on PLGA nanofibers produced by electrospinning
title Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
spellingShingle Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
Braghirolli, Daikelly Iglesias
Esterilização
Nanofibras
Nanofibers
Electrospinning
Tissue engineering
title_short Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
title_full Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
title_fullStr Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
title_full_unstemmed Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
title_sort Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
author Braghirolli, Daikelly Iglesias
author_facet Braghirolli, Daikelly Iglesias
author_role author
dc.contributor.author.fl_str_mv Braghirolli, Daikelly Iglesias
dc.contributor.advisor1.fl_str_mv Pranke, Patricia Helena Lucas
dc.contributor.advisor-co1.fl_str_mv Steffens, Daniela
contributor_str_mv Pranke, Patricia Helena Lucas
Steffens, Daniela
dc.subject.por.fl_str_mv Esterilização
Nanofibras
topic Esterilização
Nanofibras
Nanofibers
Electrospinning
Tissue engineering
dc.subject.eng.fl_str_mv Nanofibers
Electrospinning
Tissue engineering
description The effect of sterilization using ethanol, ultraviolet radiation (UVR) and antibiotic solution in PLGA scaffolds produced by electrospinning was evaluated. The properties of nanofibers and on the cellular adhesion were analysed. All methods generated sterile scaffolds but led to some kind of damage. Ethanol and antibiotics caused changes in morphology and dimensions of scaffolds, which was not observed when using UVR. On the other hand, UVR caused a greater reduction of molecular weight which increased with exposure time. Nanofibres sterilized with antibiotics showed greater cellular adhesion than the others methods, demonstrating their potentiality as a method to sterilize PLGA nanofibers.
publishDate 2010
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