Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/26814 |
Resumo: | The effect of sterilization using ethanol, ultraviolet radiation (UVR) and antibiotic solution in PLGA scaffolds produced by electrospinning was evaluated. The properties of nanofibers and on the cellular adhesion were analysed. All methods generated sterile scaffolds but led to some kind of damage. Ethanol and antibiotics caused changes in morphology and dimensions of scaffolds, which was not observed when using UVR. On the other hand, UVR caused a greater reduction of molecular weight which increased with exposure time. Nanofibres sterilized with antibiotics showed greater cellular adhesion than the others methods, demonstrating their potentiality as a method to sterilize PLGA nanofibers. |
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Braghirolli, Daikelly IglesiasPranke, Patricia Helena LucasSteffens, Daniela2010-11-23T04:19:25Z2010http://hdl.handle.net/10183/26814000758433The effect of sterilization using ethanol, ultraviolet radiation (UVR) and antibiotic solution in PLGA scaffolds produced by electrospinning was evaluated. The properties of nanofibers and on the cellular adhesion were analysed. All methods generated sterile scaffolds but led to some kind of damage. Ethanol and antibiotics caused changes in morphology and dimensions of scaffolds, which was not observed when using UVR. On the other hand, UVR caused a greater reduction of molecular weight which increased with exposure time. Nanofibres sterilized with antibiotics showed greater cellular adhesion than the others methods, demonstrating their potentiality as a method to sterilize PLGA nanofibers.application/pdfporEsterilizaçãoNanofibrasNanofibersElectrospinningTissue engineeringEfeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinningThe effect of different sterilization methods on PLGA nanofibers produced by electrospinning info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal do Rio Grande do SulFaculdade de FarmáciaPorto Alegre, BR-RS2010Farmáciagraduaçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000758433.pdf000758433.pdfTexto completoapplication/pdf1506042http://www.lume.ufrgs.br/bitstream/10183/26814/1/000758433.pdf82563b988acd282a03b294086a65927eMD51TEXT000758433.pdf.txt000758433.pdf.txtExtracted Texttext/plain49959http://www.lume.ufrgs.br/bitstream/10183/26814/2/000758433.pdf.txtc2dabefbe4f0aff9b71fe084ba027c3eMD52THUMBNAIL000758433.pdf.jpg000758433.pdf.jpgGenerated Thumbnailimage/jpeg1089http://www.lume.ufrgs.br/bitstream/10183/26814/3/000758433.pdf.jpga10367f760e0e94d0d19ffd0dbf3ef14MD5310183/268142018-10-18 07:38:03.425oai:www.lume.ufrgs.br:10183/26814Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-18T10:38:03Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning |
dc.title.alternative.en.fl_str_mv |
The effect of different sterilization methods on PLGA nanofibers produced by electrospinning |
title |
Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning |
spellingShingle |
Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning Braghirolli, Daikelly Iglesias Esterilização Nanofibras Nanofibers Electrospinning Tissue engineering |
title_short |
Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning |
title_full |
Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning |
title_fullStr |
Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning |
title_full_unstemmed |
Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning |
title_sort |
Efeito de diferentes métodos de esterilização sobre nanofibras de plga produzidas por electrospinning |
author |
Braghirolli, Daikelly Iglesias |
author_facet |
Braghirolli, Daikelly Iglesias |
author_role |
author |
dc.contributor.author.fl_str_mv |
Braghirolli, Daikelly Iglesias |
dc.contributor.advisor1.fl_str_mv |
Pranke, Patricia Helena Lucas |
dc.contributor.advisor-co1.fl_str_mv |
Steffens, Daniela |
contributor_str_mv |
Pranke, Patricia Helena Lucas Steffens, Daniela |
dc.subject.por.fl_str_mv |
Esterilização Nanofibras |
topic |
Esterilização Nanofibras Nanofibers Electrospinning Tissue engineering |
dc.subject.eng.fl_str_mv |
Nanofibers Electrospinning Tissue engineering |
description |
The effect of sterilization using ethanol, ultraviolet radiation (UVR) and antibiotic solution in PLGA scaffolds produced by electrospinning was evaluated. The properties of nanofibers and on the cellular adhesion were analysed. All methods generated sterile scaffolds but led to some kind of damage. Ethanol and antibiotics caused changes in morphology and dimensions of scaffolds, which was not observed when using UVR. On the other hand, UVR caused a greater reduction of molecular weight which increased with exposure time. Nanofibres sterilized with antibiotics showed greater cellular adhesion than the others methods, demonstrating their potentiality as a method to sterilize PLGA nanofibers. |
publishDate |
2010 |
dc.date.accessioned.fl_str_mv |
2010-11-23T04:19:25Z |
dc.date.issued.fl_str_mv |
2010 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/bachelorThesis |
format |
bachelorThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/26814 |
dc.identifier.nrb.pt_BR.fl_str_mv |
000758433 |
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http://hdl.handle.net/10183/26814 |
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por |
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openAccess |
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application/pdf |
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