Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/265539 |
Resumo: | Background Nut consumption has been related to improvements on cardiometabolic parameters and reduction in the severity of atherosclerosis mainly in primary cardiovascular prevention. The objective of this trial is to evaluate the effects of the Brazilian Cardioprotective Diet (DIeta CArdioprotetora Brasileira, DICA Br) based on consumption of inexpensive locally accessible foods supplemented or not with mixed nuts on cardiometabolic features in patients with previous myocardial infarction (MI). Methods DICA-NUTS study is a national, multicenter, randomized 16-week follow-up clinical trial. Patients over 40 years old with diagnosis of previous MI in the last 2 to 6 months will be recruited (n = 388). A standardized questionnaire will be applied to data collection and blood samples will be obtained. Patients will be allocated in two groups: Group 1: DICA Br supplemented with 30 g/day of mixed nuts (10 g of peanuts, 10 g of cashew, 10 g of Brazil nuts); and Group 2: only DICA Br. The primary outcome will consist of LDL cholesterol means (in mg/dL) after 16 weeks of intervention. Secondary outcomes will consist of other markers of lipid profile, glycemic profile, and anthropometric data. Discussion It is expected that DICA Br supplemented with mixed nuts have superior beneficial effects on cardiometabolic parameters in patients after a MI, when compared to DICA Br. Trial registration ClinicalTrials.gov Identifier NCT03728127. First register: November 1, 2018; Last update: June 16, 2021. World Health Organization Universal Trial Number (WHO-UTN): U1111-1259-8105. |
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Oliveira, Aline Marcadenti deSouza, Gabriela CorrêaParahiba, Suena MedeirosCavalcanti, Alexandre Biasi2023-09-30T03:41:49Z20211745-6215http://hdl.handle.net/10183/265539001172530Background Nut consumption has been related to improvements on cardiometabolic parameters and reduction in the severity of atherosclerosis mainly in primary cardiovascular prevention. The objective of this trial is to evaluate the effects of the Brazilian Cardioprotective Diet (DIeta CArdioprotetora Brasileira, DICA Br) based on consumption of inexpensive locally accessible foods supplemented or not with mixed nuts on cardiometabolic features in patients with previous myocardial infarction (MI). Methods DICA-NUTS study is a national, multicenter, randomized 16-week follow-up clinical trial. Patients over 40 years old with diagnosis of previous MI in the last 2 to 6 months will be recruited (n = 388). A standardized questionnaire will be applied to data collection and blood samples will be obtained. Patients will be allocated in two groups: Group 1: DICA Br supplemented with 30 g/day of mixed nuts (10 g of peanuts, 10 g of cashew, 10 g of Brazil nuts); and Group 2: only DICA Br. The primary outcome will consist of LDL cholesterol means (in mg/dL) after 16 weeks of intervention. Secondary outcomes will consist of other markers of lipid profile, glycemic profile, and anthropometric data. Discussion It is expected that DICA Br supplemented with mixed nuts have superior beneficial effects on cardiometabolic parameters in patients after a MI, when compared to DICA Br. Trial registration ClinicalTrials.gov Identifier NCT03728127. First register: November 1, 2018; Last update: June 16, 2021. World Health Organization Universal Trial Number (WHO-UTN): U1111-1259-8105.application/pdfengTrials. London. Vol. 22 (2021), artigo 582, 16 p.Infarto do miocárdioDieta saudávelAterosclerosePrevenção secundáriaNozesMyocardial infarctionNutsAtherosclerosisSecondary preventionDiet, HealthyBertholletia anacardiumAnacardiumEffects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trialEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001172530.pdf.txt001172530.pdf.txtExtracted Texttext/plain79975http://www.lume.ufrgs.br/bitstream/10183/265539/3/001172530.pdf.txtac36a2828cec271e617232870d51c18fMD53001172530-02.pdf.txt001172530-02.pdf.txtExtracted Texttext/plain5794http://www.lume.ufrgs.br/bitstream/10183/265539/4/001172530-02.pdf.txt3655d799c365693cb31e33c3601ac078MD54ORIGINAL001172530.pdfTexto completo (inglês)application/pdf1018134http://www.lume.ufrgs.br/bitstream/10183/265539/1/001172530.pdfd8bf4feb66c22e00c1166c8f6bd9fa18MD51001172530-02.pdfErrataapplication/pdf191038http://www.lume.ufrgs.br/bitstream/10183/265539/2/001172530-02.pdf91b7dc976288306ccf018fc5f5ffbc44MD5210183/2655392023-10-01 03:38:37.57959oai:www.lume.ufrgs.br:10183/265539Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-10-01T06:38:37Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial |
title |
Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial |
spellingShingle |
Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial Oliveira, Aline Marcadenti de Infarto do miocárdio Dieta saudável Aterosclerose Prevenção secundária Nozes Myocardial infarction Nuts Atherosclerosis Secondary prevention Diet, Healthy Bertholletia anacardium Anacardium |
title_short |
Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial |
title_full |
Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial |
title_fullStr |
Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial |
title_full_unstemmed |
Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial |
title_sort |
Effects of a Brazilian cardioprotective diet and nuts on cardiometabolic parameters after myocardial infarction : study protocol for a randomized controlled clinical trial |
author |
Oliveira, Aline Marcadenti de |
author_facet |
Oliveira, Aline Marcadenti de Souza, Gabriela Corrêa Parahiba, Suena Medeiros Cavalcanti, Alexandre Biasi |
author_role |
author |
author2 |
Souza, Gabriela Corrêa Parahiba, Suena Medeiros Cavalcanti, Alexandre Biasi |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Aline Marcadenti de Souza, Gabriela Corrêa Parahiba, Suena Medeiros Cavalcanti, Alexandre Biasi |
dc.subject.por.fl_str_mv |
Infarto do miocárdio Dieta saudável Aterosclerose Prevenção secundária Nozes |
topic |
Infarto do miocárdio Dieta saudável Aterosclerose Prevenção secundária Nozes Myocardial infarction Nuts Atherosclerosis Secondary prevention Diet, Healthy Bertholletia anacardium Anacardium |
dc.subject.eng.fl_str_mv |
Myocardial infarction Nuts Atherosclerosis Secondary prevention Diet, Healthy Bertholletia anacardium Anacardium |
description |
Background Nut consumption has been related to improvements on cardiometabolic parameters and reduction in the severity of atherosclerosis mainly in primary cardiovascular prevention. The objective of this trial is to evaluate the effects of the Brazilian Cardioprotective Diet (DIeta CArdioprotetora Brasileira, DICA Br) based on consumption of inexpensive locally accessible foods supplemented or not with mixed nuts on cardiometabolic features in patients with previous myocardial infarction (MI). Methods DICA-NUTS study is a national, multicenter, randomized 16-week follow-up clinical trial. Patients over 40 years old with diagnosis of previous MI in the last 2 to 6 months will be recruited (n = 388). A standardized questionnaire will be applied to data collection and blood samples will be obtained. Patients will be allocated in two groups: Group 1: DICA Br supplemented with 30 g/day of mixed nuts (10 g of peanuts, 10 g of cashew, 10 g of Brazil nuts); and Group 2: only DICA Br. The primary outcome will consist of LDL cholesterol means (in mg/dL) after 16 weeks of intervention. Secondary outcomes will consist of other markers of lipid profile, glycemic profile, and anthropometric data. Discussion It is expected that DICA Br supplemented with mixed nuts have superior beneficial effects on cardiometabolic parameters in patients after a MI, when compared to DICA Br. Trial registration ClinicalTrials.gov Identifier NCT03728127. First register: November 1, 2018; Last update: June 16, 2021. World Health Organization Universal Trial Number (WHO-UTN): U1111-1259-8105. |
publishDate |
2021 |
dc.date.issued.fl_str_mv |
2021 |
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2023-09-30T03:41:49Z |
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1745-6215 |
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Trials. London. Vol. 22 (2021), artigo 582, 16 p. |
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