Prevalence of HPV infection by cervical cytologic status in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/handle/123456789/52038 |
Resumo: | Objectives: To assess the prevalence of human papillomavirus (HPV) infection according to cervical cytologic status in northeastern Brazil; identify other risk factors for low- and high-grade squamous intraepithelial lesions (LSILs and HSILs); and identify the most prevalent HPV genotypes associated with the lesions. Method: Two cervical smears were collected from 250 women referred for cancer screening, one for cytologic examination and the other to test for the presence of HPV by PCR with genotyping by dot blot hybridization. Result: There were 110 healthy cervices, 82 LSILs, and 58 HSILs. The overall HPV prevalence was 48%, with higher rates for HSILs, and HPV-16 was the most prevalent type. Age, multiple sexual partners, type of HPV present, smoking, and early onset of sexual activity were risk factors for cervical lesions. Conclusion: Age, multiple sexual partners, and infection with HPV-16 increased the risk of having LSILs or HSILs. Early onset of sexual activity and smoking only increased the risk of having HSILs. |
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Fernandes, José VeríssimoMeissner, Rosely de VasconcellosCarvalho, Maria Goretti Freire deFernandes, Thales Allyrio Araújo de MedeirosAzevedo, Paulo Roberto Medeiros deVilla, Luisa Lina2023-04-04T21:05:22Z2023-04-04T21:05:22Z2009FERNANDES, José Veríssimo et al. Prevalence of HPV infection by cervical cytologic status in Brazil. International Journal of Gynecology & Obstetrics, v. 105, n. 1, p. 21-24, 2009. Disponível em: https://www.sciencedirect.com/science/article/pii/S0020729208005730. Acesso em: 4 abr. 2023.0020-7292https://repositorio.ufrn.br/handle/123456789/5203810.1016International Journal of Gynecology and ObstetricsCervical lesionsHuman papillomavirusPolymerase chain reactionRisk factorsPrevalence of HPV infection by cervical cytologic status in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleObjectives: To assess the prevalence of human papillomavirus (HPV) infection according to cervical cytologic status in northeastern Brazil; identify other risk factors for low- and high-grade squamous intraepithelial lesions (LSILs and HSILs); and identify the most prevalent HPV genotypes associated with the lesions. Method: Two cervical smears were collected from 250 women referred for cancer screening, one for cytologic examination and the other to test for the presence of HPV by PCR with genotyping by dot blot hybridization. Result: There were 110 healthy cervices, 82 LSILs, and 58 HSILs. The overall HPV prevalence was 48%, with higher rates for HSILs, and HPV-16 was the most prevalent type. Age, multiple sexual partners, type of HPV present, smoking, and early onset of sexual activity were risk factors for cervical lesions. Conclusion: Age, multiple sexual partners, and infection with HPV-16 increased the risk of having LSILs or HSILs. Early onset of sexual activity and smoking only increased the risk of having HSILs.info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALPrevalenceOfHPVinfection_Fernandes__2009.pdfPrevalenceOfHPVinfection_Fernandes__2009.pdfapplication/pdf151326https://repositorio.ufrn.br/bitstream/123456789/52038/1/PrevalenceOfHPVinfection_Fernandes__2009.pdf5fecdc0d430073f40878ab786b03624bMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.ufrn.br/bitstream/123456789/52038/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52123456789/520382023-04-04 18:06:03.812oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2023-04-04T21:06:03Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Prevalence of HPV infection by cervical cytologic status in Brazil |
title |
Prevalence of HPV infection by cervical cytologic status in Brazil |
spellingShingle |
Prevalence of HPV infection by cervical cytologic status in Brazil Fernandes, José Veríssimo Cervical lesions Human papillomavirus Polymerase chain reaction Risk factors |
title_short |
Prevalence of HPV infection by cervical cytologic status in Brazil |
title_full |
Prevalence of HPV infection by cervical cytologic status in Brazil |
title_fullStr |
Prevalence of HPV infection by cervical cytologic status in Brazil |
title_full_unstemmed |
Prevalence of HPV infection by cervical cytologic status in Brazil |
title_sort |
Prevalence of HPV infection by cervical cytologic status in Brazil |
author |
Fernandes, José Veríssimo |
author_facet |
Fernandes, José Veríssimo Meissner, Rosely de Vasconcellos Carvalho, Maria Goretti Freire de Fernandes, Thales Allyrio Araújo de Medeiros Azevedo, Paulo Roberto Medeiros de Villa, Luisa Lina |
author_role |
author |
author2 |
Meissner, Rosely de Vasconcellos Carvalho, Maria Goretti Freire de Fernandes, Thales Allyrio Araújo de Medeiros Azevedo, Paulo Roberto Medeiros de Villa, Luisa Lina |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Fernandes, José Veríssimo Meissner, Rosely de Vasconcellos Carvalho, Maria Goretti Freire de Fernandes, Thales Allyrio Araújo de Medeiros Azevedo, Paulo Roberto Medeiros de Villa, Luisa Lina |
dc.subject.por.fl_str_mv |
Cervical lesions Human papillomavirus Polymerase chain reaction Risk factors |
topic |
Cervical lesions Human papillomavirus Polymerase chain reaction Risk factors |
description |
Objectives: To assess the prevalence of human papillomavirus (HPV) infection according to cervical cytologic status in northeastern Brazil; identify other risk factors for low- and high-grade squamous intraepithelial lesions (LSILs and HSILs); and identify the most prevalent HPV genotypes associated with the lesions. Method: Two cervical smears were collected from 250 women referred for cancer screening, one for cytologic examination and the other to test for the presence of HPV by PCR with genotyping by dot blot hybridization. Result: There were 110 healthy cervices, 82 LSILs, and 58 HSILs. The overall HPV prevalence was 48%, with higher rates for HSILs, and HPV-16 was the most prevalent type. Age, multiple sexual partners, type of HPV present, smoking, and early onset of sexual activity were risk factors for cervical lesions. Conclusion: Age, multiple sexual partners, and infection with HPV-16 increased the risk of having LSILs or HSILs. Early onset of sexual activity and smoking only increased the risk of having HSILs. |
publishDate |
2009 |
dc.date.issued.fl_str_mv |
2009 |
dc.date.accessioned.fl_str_mv |
2023-04-04T21:05:22Z |
dc.date.available.fl_str_mv |
2023-04-04T21:05:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
FERNANDES, José Veríssimo et al. Prevalence of HPV infection by cervical cytologic status in Brazil. International Journal of Gynecology & Obstetrics, v. 105, n. 1, p. 21-24, 2009. Disponível em: https://www.sciencedirect.com/science/article/pii/S0020729208005730. Acesso em: 4 abr. 2023. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/handle/123456789/52038 |
dc.identifier.issn.none.fl_str_mv |
0020-7292 |
dc.identifier.doi.none.fl_str_mv |
10.1016 |
identifier_str_mv |
FERNANDES, José Veríssimo et al. Prevalence of HPV infection by cervical cytologic status in Brazil. International Journal of Gynecology & Obstetrics, v. 105, n. 1, p. 21-24, 2009. Disponível em: https://www.sciencedirect.com/science/article/pii/S0020729208005730. Acesso em: 4 abr. 2023. 0020-7292 10.1016 |
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https://repositorio.ufrn.br/handle/123456789/52038 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
International Journal of Gynecology and Obstetrics |
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International Journal of Gynecology and Obstetrics |
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reponame:Repositório Institucional da UFRN instname:Universidade Federal do Rio Grande do Norte (UFRN) instacron:UFRN |
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