Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms

Detalhes bibliográficos
Autor(a) principal: Engelberth, Rovena C. G. J.
Data de Publicação: 2013
Outros Autores: Pontes, André L. Bezerra de, Fiuza, Felipe Porto, Silva, Kayo D. de Azevedo, Resende, Nayra da S., Azevedo, Carolina Virgínia de M., Costa, Miriam S. M. O., Cavalcante, Judney C., Nascimento Júnior, Expedito S., Gavioli, Elaine Cristina, Cavalcante, Jeferson S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRN
Texto Completo: https://repositorio.ufrn.br/jspui/handle/123456789/24709
Resumo: Animals have neural structures that allow them to anticipate environmental changes and then regulate physiological and behavioral functions in response to these alterations. The suprachiasmatic nucleus of the hypothalamus (SCN) is the main circadian pacemaker in many mammalian species. This structure synchronizes the biological rhythm based on photic information that is transmitted to the SCN through the retinohypothalamic tract. The aging process changes the structural complexity of the nervous system, from individual nerve cells to global changes, including the atrophy of total gray matter. Aged animals show internal time disruptions caused by morphological and neurochemical changes in SCN components. The effects of aging on circadian rhythm range from effects on simple physiological functions to effects on complex cognitive performance, including many psychiatric disorders that influence the well-being of the elderly. In this review, we summarize the effects of aging on morphological, neurochemical, and circadian rhythmic functions coordinated by the main circadian pacemaker, the SCN
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spelling Engelberth, Rovena C. G. J.Pontes, André L. Bezerra deFiuza, Felipe PortoSilva, Kayo D. de AzevedoResende, Nayra da S.Azevedo, Carolina Virgínia de M.Costa, Miriam S. M. O.Cavalcante, Judney C.Nascimento Júnior, Expedito S.Gavioli, Elaine CristinaCavalcante, Jeferson S.2018-02-05T22:02:44Z2018-02-05T22:02:44Z2013ENGELBERTH, Rovena C. G. J. et al. Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms. Psychology and Neuroscience, v. 6, p. 287-297, 2013. Disponível em:<http://doi.apa.org/fulltext/2014-01602-007.html>. Acesso em: 20 nov. 2017.https://repositorio.ufrn.br/jspui/handle/123456789/2470910.3922/j.psns.2013.3.07engSuprachiasmatic nucleusAgingMorphologicalCircadian rhythmsChanges in the suprachiasmatic nucleus during aging: implications for biological rhythmsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAnimals have neural structures that allow them to anticipate environmental changes and then regulate physiological and behavioral functions in response to these alterations. The suprachiasmatic nucleus of the hypothalamus (SCN) is the main circadian pacemaker in many mammalian species. This structure synchronizes the biological rhythm based on photic information that is transmitted to the SCN through the retinohypothalamic tract. The aging process changes the structural complexity of the nervous system, from individual nerve cells to global changes, including the atrophy of total gray matter. Aged animals show internal time disruptions caused by morphological and neurochemical changes in SCN components. The effects of aging on circadian rhythm range from effects on simple physiological functions to effects on complex cognitive performance, including many psychiatric disorders that influence the well-being of the elderly. In this review, we summarize the effects of aging on morphological, neurochemical, and circadian rhythmic functions coordinated by the main circadian pacemaker, the SCNinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNTEXTChanges_in_the_suprachiasmatic.pdf.txtChanges_in_the_suprachiasmatic.pdf.txtExtracted texttext/plain67187https://repositorio.ufrn.br/bitstream/123456789/24709/3/Changes_in_the_suprachiasmatic.pdf.txt4eff0a8eb03a61670a855c527e85513eMD53THUMBNAILChanges_in_the_suprachiasmatic.pdf.jpgChanges_in_the_suprachiasmatic.pdf.jpgIM Thumbnailimage/jpeg12115https://repositorio.ufrn.br/bitstream/123456789/24709/4/Changes_in_the_suprachiasmatic.pdf.jpg4b4e9ec4840623a86b6dc0a0cf7d6e27MD54TEXTChanges_in_the_suprachiasmatic.pdf.txtChanges_in_the_suprachiasmatic.pdf.txtExtracted texttext/plain67187https://repositorio.ufrn.br/bitstream/123456789/24709/3/Changes_in_the_suprachiasmatic.pdf.txt4eff0a8eb03a61670a855c527e85513eMD53THUMBNAILChanges_in_the_suprachiasmatic.pdf.jpgChanges_in_the_suprachiasmatic.pdf.jpgIM Thumbnailimage/jpeg12115https://repositorio.ufrn.br/bitstream/123456789/24709/4/Changes_in_the_suprachiasmatic.pdf.jpg4b4e9ec4840623a86b6dc0a0cf7d6e27MD54ORIGINALChangesSuprachiasmaticNucleus_Engelberth_2013.pdfChangesSuprachiasmaticNucleus_Engelberth_2013.pdfapplication/pdf1125171https://repositorio.ufrn.br/bitstream/123456789/24709/1/ChangesSuprachiasmaticNucleus_Engelberth_2013.pdf05d8bf0dc1fb4e85e6591ff3cd354b4aMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.ufrn.br/bitstream/123456789/24709/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52123456789/247092021-11-09 15:07:04.786oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-11-09T18:07:04Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.pt_BR.fl_str_mv Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
title Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
spellingShingle Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
Engelberth, Rovena C. G. J.
Suprachiasmatic nucleus
Aging
Morphological
Circadian rhythms
title_short Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
title_full Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
title_fullStr Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
title_full_unstemmed Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
title_sort Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
author Engelberth, Rovena C. G. J.
author_facet Engelberth, Rovena C. G. J.
Pontes, André L. Bezerra de
Fiuza, Felipe Porto
Silva, Kayo D. de Azevedo
Resende, Nayra da S.
Azevedo, Carolina Virgínia de M.
Costa, Miriam S. M. O.
Cavalcante, Judney C.
Nascimento Júnior, Expedito S.
Gavioli, Elaine Cristina
Cavalcante, Jeferson S.
author_role author
author2 Pontes, André L. Bezerra de
Fiuza, Felipe Porto
Silva, Kayo D. de Azevedo
Resende, Nayra da S.
Azevedo, Carolina Virgínia de M.
Costa, Miriam S. M. O.
Cavalcante, Judney C.
Nascimento Júnior, Expedito S.
Gavioli, Elaine Cristina
Cavalcante, Jeferson S.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Engelberth, Rovena C. G. J.
Pontes, André L. Bezerra de
Fiuza, Felipe Porto
Silva, Kayo D. de Azevedo
Resende, Nayra da S.
Azevedo, Carolina Virgínia de M.
Costa, Miriam S. M. O.
Cavalcante, Judney C.
Nascimento Júnior, Expedito S.
Gavioli, Elaine Cristina
Cavalcante, Jeferson S.
dc.subject.por.fl_str_mv Suprachiasmatic nucleus
Aging
Morphological
Circadian rhythms
topic Suprachiasmatic nucleus
Aging
Morphological
Circadian rhythms
description Animals have neural structures that allow them to anticipate environmental changes and then regulate physiological and behavioral functions in response to these alterations. The suprachiasmatic nucleus of the hypothalamus (SCN) is the main circadian pacemaker in many mammalian species. This structure synchronizes the biological rhythm based on photic information that is transmitted to the SCN through the retinohypothalamic tract. The aging process changes the structural complexity of the nervous system, from individual nerve cells to global changes, including the atrophy of total gray matter. Aged animals show internal time disruptions caused by morphological and neurochemical changes in SCN components. The effects of aging on circadian rhythm range from effects on simple physiological functions to effects on complex cognitive performance, including many psychiatric disorders that influence the well-being of the elderly. In this review, we summarize the effects of aging on morphological, neurochemical, and circadian rhythmic functions coordinated by the main circadian pacemaker, the SCN
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2018-02-05T22:02:44Z
dc.date.available.fl_str_mv 2018-02-05T22:02:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.citation.fl_str_mv ENGELBERTH, Rovena C. G. J. et al. Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms. Psychology and Neuroscience, v. 6, p. 287-297, 2013. Disponível em:<http://doi.apa.org/fulltext/2014-01602-007.html>. Acesso em: 20 nov. 2017.
dc.identifier.uri.fl_str_mv https://repositorio.ufrn.br/jspui/handle/123456789/24709
dc.identifier.doi.none.fl_str_mv 10.3922/j.psns.2013.3.07
identifier_str_mv ENGELBERTH, Rovena C. G. J. et al. Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms. Psychology and Neuroscience, v. 6, p. 287-297, 2013. Disponível em:<http://doi.apa.org/fulltext/2014-01602-007.html>. Acesso em: 20 nov. 2017.
10.3922/j.psns.2013.3.07
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