Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha
Autor(a) principal: | |
---|---|
Data de Publicação: | 2012 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/jspui/handle/123456789/23179 |
Resumo: | The cerebral cortex is often described as a composite of repeated units or columns, integrating the same basic circuit. The ‘ice-cube’ model of cortical organization, and ‘canonical’ circuit, born from insights into functional architecture, still require systematic comparative data. Here we probed the anatomy of an individual neuronal type within V1 to determine whether or not its dendritic trees are consistent with the ‘ice-cube’ model and theories of canonical circuits. In a previous report we studied the morphometric variability of NADPH-diaphorase (NADPH-d) neurons in the rat auditory, visual and somatosensory primary cortical areas. Our results suggested that the nitrergic cortical circuitry of primary sensory areas are differentially specialized, probably reflecting peculiarities of both habit and behavior of the species. In the present report we specifically quantified the dendritic trees of NADPH-d type I neurons as a function of eccentricity within V1. Individual neurons were reconstructed in 3D, and the size, branching and spacefilling of their dendritic trees were correlated with their location within the visuotopic map. We found that NADPH-d neurons became progressively smaller and less branched with progression from the central visual representation to the intermediate and peripheral visual representation. This finding suggests that aspects of cortical circuitry may vary across the cortical mantle to a greater extent that envisaged as natural variation among columns in the ‘ice-cube’ model. The systematic variation in neuronal structure as a function of eccentricity warrants further investigation to probe the general applicability of columnar models of cortical organization and canonical circuits. |
id |
UFRN_904a6e0a21bd1fc15e11fadbf5fbef9f |
---|---|
oai_identifier_str |
oai:https://repositorio.ufrn.br:123456789/23179 |
network_acronym_str |
UFRN |
network_name_str |
Repositório Institucional da UFRN |
repository_id_str |
|
spelling |
ROCHA, E. G. DAFREIRE, M. A. M.BAHIA, C. P.PEREIRA, A.SOSTHENES, M. C. K.SILVEIRA, L. C. L.ELSTON, G. N.PICANC¸ O-DINIZ, C. W.2017-05-29T14:12:15Z2017-05-29T14:12:15Z20120306-4522https://repositorio.ufrn.br/jspui/handle/123456789/23179engAgoutiArea 17Striate cortexVisual streakDendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolophainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleThe cerebral cortex is often described as a composite of repeated units or columns, integrating the same basic circuit. The ‘ice-cube’ model of cortical organization, and ‘canonical’ circuit, born from insights into functional architecture, still require systematic comparative data. Here we probed the anatomy of an individual neuronal type within V1 to determine whether or not its dendritic trees are consistent with the ‘ice-cube’ model and theories of canonical circuits. In a previous report we studied the morphometric variability of NADPH-diaphorase (NADPH-d) neurons in the rat auditory, visual and somatosensory primary cortical areas. Our results suggested that the nitrergic cortical circuitry of primary sensory areas are differentially specialized, probably reflecting peculiarities of both habit and behavior of the species. In the present report we specifically quantified the dendritic trees of NADPH-d type I neurons as a function of eccentricity within V1. Individual neurons were reconstructed in 3D, and the size, branching and spacefilling of their dendritic trees were correlated with their location within the visuotopic map. We found that NADPH-d neurons became progressively smaller and less branched with progression from the central visual representation to the intermediate and peripheral visual representation. This finding suggests that aspects of cortical circuitry may vary across the cortical mantle to a greater extent that envisaged as natural variation among columns in the ‘ice-cube’ model. The systematic variation in neuronal structure as a function of eccentricity warrants further investigation to probe the general applicability of columnar models of cortical organization and canonical circuits.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALDendritic structure varies as a function of eccentricity in V1.pdfDendritic structure varies as a function of eccentricity in V1.pdfArtigo completoapplication/pdf743043https://repositorio.ufrn.br/bitstream/123456789/23179/1/Dendritic%20structure%20varies%20as%20a%20function%20of%20eccentricity%20in%20V1.pdf3c0d68507c4ab29fd10d7486ff6714d6MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.ufrn.br/bitstream/123456789/23179/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTDendritic structure varies as a function of eccentricity in V1.pdf.txtDendritic structure varies as a function of eccentricity in V1.pdf.txtExtracted texttext/plain44918https://repositorio.ufrn.br/bitstream/123456789/23179/5/Dendritic%20structure%20varies%20as%20a%20function%20of%20eccentricity%20in%20V1.pdf.txtbc5bdd057bf42cf3123045e280335d99MD55THUMBNAILDendritic structure varies as a function of eccentricity in V1.pdf.jpgDendritic structure varies as a function of eccentricity in V1.pdf.jpgIM Thumbnailimage/jpeg10002https://repositorio.ufrn.br/bitstream/123456789/23179/6/Dendritic%20structure%20varies%20as%20a%20function%20of%20eccentricity%20in%20V1.pdf.jpgb6b1d053d65c963e394eaef5f89bbec6MD56123456789/231792017-11-04 19:53:19.09oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2017-11-04T22:53:19Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
title |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
spellingShingle |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha ROCHA, E. G. DA Agouti Area 17 Striate cortex Visual streak |
title_short |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
title_full |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
title_fullStr |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
title_full_unstemmed |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
title_sort |
Dendritic structure varies as a function of eccentricity in V1: a quantitative study of Nadph Diaphorase neurons in the diurnal south american rodent agouti, Dasyprocta Prymnolopha |
author |
ROCHA, E. G. DA |
author_facet |
ROCHA, E. G. DA FREIRE, M. A. M. BAHIA, C. P. PEREIRA, A. SOSTHENES, M. C. K. SILVEIRA, L. C. L. ELSTON, G. N. PICANC¸ O-DINIZ, C. W. |
author_role |
author |
author2 |
FREIRE, M. A. M. BAHIA, C. P. PEREIRA, A. SOSTHENES, M. C. K. SILVEIRA, L. C. L. ELSTON, G. N. PICANC¸ O-DINIZ, C. W. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
ROCHA, E. G. DA FREIRE, M. A. M. BAHIA, C. P. PEREIRA, A. SOSTHENES, M. C. K. SILVEIRA, L. C. L. ELSTON, G. N. PICANC¸ O-DINIZ, C. W. |
dc.subject.por.fl_str_mv |
Agouti Area 17 Striate cortex Visual streak |
topic |
Agouti Area 17 Striate cortex Visual streak |
description |
The cerebral cortex is often described as a composite of repeated units or columns, integrating the same basic circuit. The ‘ice-cube’ model of cortical organization, and ‘canonical’ circuit, born from insights into functional architecture, still require systematic comparative data. Here we probed the anatomy of an individual neuronal type within V1 to determine whether or not its dendritic trees are consistent with the ‘ice-cube’ model and theories of canonical circuits. In a previous report we studied the morphometric variability of NADPH-diaphorase (NADPH-d) neurons in the rat auditory, visual and somatosensory primary cortical areas. Our results suggested that the nitrergic cortical circuitry of primary sensory areas are differentially specialized, probably reflecting peculiarities of both habit and behavior of the species. In the present report we specifically quantified the dendritic trees of NADPH-d type I neurons as a function of eccentricity within V1. Individual neurons were reconstructed in 3D, and the size, branching and spacefilling of their dendritic trees were correlated with their location within the visuotopic map. We found that NADPH-d neurons became progressively smaller and less branched with progression from the central visual representation to the intermediate and peripheral visual representation. This finding suggests that aspects of cortical circuitry may vary across the cortical mantle to a greater extent that envisaged as natural variation among columns in the ‘ice-cube’ model. The systematic variation in neuronal structure as a function of eccentricity warrants further investigation to probe the general applicability of columnar models of cortical organization and canonical circuits. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2017-05-29T14:12:15Z |
dc.date.available.fl_str_mv |
2017-05-29T14:12:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/jspui/handle/123456789/23179 |
dc.identifier.issn.none.fl_str_mv |
0306-4522 |
identifier_str_mv |
0306-4522 |
url |
https://repositorio.ufrn.br/jspui/handle/123456789/23179 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFRN instname:Universidade Federal do Rio Grande do Norte (UFRN) instacron:UFRN |
instname_str |
Universidade Federal do Rio Grande do Norte (UFRN) |
instacron_str |
UFRN |
institution |
UFRN |
reponame_str |
Repositório Institucional da UFRN |
collection |
Repositório Institucional da UFRN |
bitstream.url.fl_str_mv |
https://repositorio.ufrn.br/bitstream/123456789/23179/1/Dendritic%20structure%20varies%20as%20a%20function%20of%20eccentricity%20in%20V1.pdf https://repositorio.ufrn.br/bitstream/123456789/23179/2/license.txt https://repositorio.ufrn.br/bitstream/123456789/23179/5/Dendritic%20structure%20varies%20as%20a%20function%20of%20eccentricity%20in%20V1.pdf.txt https://repositorio.ufrn.br/bitstream/123456789/23179/6/Dendritic%20structure%20varies%20as%20a%20function%20of%20eccentricity%20in%20V1.pdf.jpg |
bitstream.checksum.fl_str_mv |
3c0d68507c4ab29fd10d7486ff6714d6 8a4605be74aa9ea9d79846c1fba20a33 bc5bdd057bf42cf3123045e280335d99 b6b1d053d65c963e394eaef5f89bbec6 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN) |
repository.mail.fl_str_mv |
|
_version_ |
1797776969378562048 |