Predictors of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study

• Autor(a) principal: Fayh, Ana Paula Trussardi
• Data de Publicação: 2018
• Outros Autores: Aquino, Séphora Louyse Silva, Cunha, Aline Tuane Oliveira da, Pereira, Hermilla Torres, Freitas, Erika Paula Silva, Lima, Josivan Gomes, Lima, Severina Carla Vieira Cunha, Sena-Evangelista, Karine Cavalcanti Maurício, Pedrosa, Lucia Fátima Campos
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRN
• Texto Completo: https://repositorio.ufrn.br/handle/123456789/55611; https://doi.org/10.1186/s13098-018-0346-1
• topic: Metabolic syndrome; vitamin D; sun exposure; seasonal variation

Background: The risk of metabolic syndrome can be infuenced by inadequate vitamin D levels, and exposure to sunlight is the main external source of vitamin D. The present study assessed the infuence of environmental, biologi‑ cal, and nutritional factors in relation to seasonal 25-hydroxyvitamin D (25OHD) concentration in individuals with metabolic syndrome. Methods: This cross-sectional study enrolled 180 individuals with metabolic syndrome aged between 18 and 80 years. The 25OHD concentration was considered the dependent variable; independent variables included age, sex, skin color, use of sunscreen, skin type, sun exposure score, ultraviolet radiation index, geographic location, season, body mass index, waist:hip ratio, waist circumference, parathyroid hormone level, total serum calcium level, and cal‑ cium and vitamin D intake. Results: The average vitamin D in individuals evaluated in summer 32±10 ng/mL was greater than in the winter 26±8 ng/mL (p<0.017). HDL-cholesterol was the only component of the MetS that difered signifcantly between the seasons (p<0.001), showing higher concentrations in autumn 45±8 mg/dL than in summer 35±8 mg/dL. In the multiple regression model, gender, WHR, sun exposure score, and winter vs. summer explained 10% of the variation in 25OHD concentration (p=0.004). Conclusions: Sex, waist:hip ratio, sun exposure, and summer season were predictors of 25OHD status among individuals with metabolic syndrome. HDL-cholesterol was the only component of metabolic syndrome that difered signifcantly between the seasons