Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro
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Data de Publicação: | 2011 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFRRJ |
Texto Completo: | https://tede.ufrrj.br/jspui/handle/jspui/1223 |
Resumo: | This study aimed to evaluate the prevalence of antibodies against Neorickettsia risticii in horses in the microregion of Itagua? RJ, show possible associated factors and identify the agent by molecular techniques. The study was conducted in the districts of Serop?dica, Itagua? and Mangaratiba, Rio de Janeiro. The 350 blood samples were obtained by convenience from horse properties belonging to the region. Serologic testing was performed by Immunofluorescence Assay (IFAI) for N. risticii, being considered positive samples titer 1:50. To evaluate risk factors associated with the presence of antibodies to N. risticii an epidemiological questionnaire was applied to the owners or guardians of animals, which aimed especially farm characteristics and management of animals. Hematological and clinical evaluation was performed for all animals. Molecular analysis by a Real Time PCR was performed from leukocyte cover. The prevalence of antibodies anti-N.risticii in horses of the region of Itagua? was 26.3% (92/350). The frequencies of IgG anti-N.rristicii were 52.2% (48/92) for titers of 1:50, zero for titers of 1:100, 13% (12/92) for titles of 1:200, 28.3% (26/92) for evidence of 1:400 and 6.5% (6 / 92) for titles of 1:800. The age and quality level of the properties were associated (p <0.05) with horses seropositivity for N. risticii. DNA from N. risticii was not detectable in samples of this study. Also no significant changes in the clinical evaluation of animals was found in relation to seropositivity for the agent. Despite showing association (p <0.05) between the seropositivity of the animals and changes in white blood cell of negative animals, these changes were not outside reference limits for the species evaluated. The existence of horses seropositive for N. risticii indicates the presence of this agent in the microregion of Itagua?. |
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Massard, Carlos Luiz257.781.297-34http://lattes.cnpq.br/7743112049924654Baldani, Cristiane Divan044.128.097-81http://lattes.cnpq.br/6210245465538447Leite, Rom?rio CerqueiraLinhares, Guido Fontgalland CoelhoBarreira, Jairo DiasGrisi, Laerte023.688.377-10http://lattes.cnpq.br/3538932429235543Roier, Erica Cristina Rocha2016-09-28T14:27:47Z2011-02-28ROIER, Erica Cristina Rocha. Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro. 2011. 43 f. Tese (Mestrado em Ci?ncias Veterin?rias) - Instituto de Veterin?ria, Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2011.https://tede.ufrrj.br/jspui/handle/jspui/1223This study aimed to evaluate the prevalence of antibodies against Neorickettsia risticii in horses in the microregion of Itagua? RJ, show possible associated factors and identify the agent by molecular techniques. The study was conducted in the districts of Serop?dica, Itagua? and Mangaratiba, Rio de Janeiro. The 350 blood samples were obtained by convenience from horse properties belonging to the region. Serologic testing was performed by Immunofluorescence Assay (IFAI) for N. risticii, being considered positive samples titer 1:50. To evaluate risk factors associated with the presence of antibodies to N. risticii an epidemiological questionnaire was applied to the owners or guardians of animals, which aimed especially farm characteristics and management of animals. Hematological and clinical evaluation was performed for all animals. Molecular analysis by a Real Time PCR was performed from leukocyte cover. The prevalence of antibodies anti-N.risticii in horses of the region of Itagua? was 26.3% (92/350). The frequencies of IgG anti-N.rristicii were 52.2% (48/92) for titers of 1:50, zero for titers of 1:100, 13% (12/92) for titles of 1:200, 28.3% (26/92) for evidence of 1:400 and 6.5% (6 / 92) for titles of 1:800. The age and quality level of the properties were associated (p <0.05) with horses seropositivity for N. risticii. DNA from N. risticii was not detectable in samples of this study. Also no significant changes in the clinical evaluation of animals was found in relation to seropositivity for the agent. Despite showing association (p <0.05) between the seropositivity of the animals and changes in white blood cell of negative animals, these changes were not outside reference limits for the species evaluated. The existence of horses seropositive for N. risticii indicates the presence of this agent in the microregion of Itagua?.O presente estudo teve por objetivo avaliar a preval?ncia de anticorpos contra Neorickettsia risticii em equinos na microrregi?o de Itagua?-RJ, demonstrar os poss?veis fatores associados e identificar o agente atrav?s de t?cnicas moleculares. O estudo foi conduzido nos munic?pios de Serop?dica, Itagua? e Mangaratiba, estado do Rio de Janeiro. As 350 amostras de sangue foram obtidas por conveni?ncia, das propriedades de cria??o de equinos pertencentes ? regi?o. O teste sorol?gico foi realizado atrav?s da Rea??o de Imunofluoresc?ncia Indireta (RIFI) para N. risticii, sendo consideradas positivas amostras com t?tulo 1:50. Para avalia??o dos fatores de risco associados ? presen?a de anticorpos de N. risticii, aplicou-se um question?rio epidemiol?gico com os propriet?rios e/ou respons?veis dos animais, destacando caracter?sticas da propriedade e manejo dos animais. Realizou-se hemograma e avalia??o cl?nica de todos os animais. As an?lises moleculares atrav?s da t?cnica de Real Time PCR foram realizadas a partir de capa leucocit?ria. A preval?ncia de anticorpos anti-N. risticii em equinos da microrregi?o de Itagua? foi de 26,3% (92/350) pela RIFI. As frequ?ncias de anticorpos IgG anti-N. risticii foram 52,2% (48/92) para titula??es de 1:50, zero para titula??es de 1:100, 13% (12/92) para t?tulos de 1:200, 28,3% (26/92) para t?tulos de 1:400 e 6,5% (6/92) para t?tulos de 1:800. A idade e o n?vel de qualidade das propriedades apresentaram associa??o (p<0,05) com a soropositividade dos equinos para N. risticii. N?o foi detectado o DNA de N. risticii nas amostras do presente estudo. Tamb?m n?o foram evidenciadas altera??es significativas na avalia??o clinica dos animais, em rela??o ? soropositividade para o agente. Apesar de haver associa??o (p<0,05) entre a soropositividade dos animais e altera??es no leucograma dos animais negativos, estas altera??es n?o estiveram fora dos limites de refer?ncia para a esp?cie animal avaliada. A exist?ncia de equinos soropositivos para N. risticii indica a circula??o desse agente na microrregi?o de Itagua?Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2016-09-28T14:27:47Z No. of bitstreams: 1 2011 - Erica Cristina Rocha Roier.pdf: 982721 bytes, checksum: 24c0654d64de8a5b21a0eea5376f828c (MD5)Made available in DSpace on 2016-09-28T14:27:47Z (GMT). No. of bitstreams: 1 2011 - Erica Cristina Rocha Roier.pdf: 982721 bytes, checksum: 24c0654d64de8a5b21a0eea5376f828c (MD5) Previous issue date: 2011-02-28CNPq - Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gicoapplication/pdfhttps://tede.ufrrj.br/retrieve/57662/2011%20-%20Erica%20Cristina%20Rocha%20Roier.pdf.jpgporUniversidade Federal Rural do Rio de JaneiroPrograma de P?s-Gradua??o em Ci?ncias Veterin?riasUFRRJBrasilInstituto de Veterin?riaATWILL, E.R.; MOHAMMED, H.O.; LOPEZ, J.W.; McCULLOCH, C.E.; DUBOVI, E.J.Cross-sectional evaluation of environmental, host and management factors associated with risk of seropositivity to Ehrlichia risticii in horses of New York state. American Journal Veterinary Research, v.57, p. 278-285, 1996. ATWILL, E.R.; MOHAMMED, H.O.; DUBOVI, E.; LOPES, J. Retrospective evaluation of factors associated with the risk of seropositivity to Ehrlichia risticii in horses in New York state. American Journal Veterinary Research, v.53, p. 1931-1934, 1992. 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New York Academy Science v.590, p.104- 110, 1990. 35 RIKIHISA, Y.; REED, S.M.; SAMS, R.A.; GORDON, J.C.; PRETZMAN, C.I. Serosurvey of horses with evidence of equine monocytic ehrlichiosis. Journal of the American Veterinary Medical Association, v.10, p. 1327-1332, 1990. RIKIHISA, Y.; JIANG, B.M. In vitro susceptibilities of Ehrlichia risticii to eight antibiotics. Antimicrobial Agents and Chemotherapy, v.32, n.7, p. 986-991, 1988. RIKIHISA, Y.; PERRY, B.D. Causative Ehrlichial organism in Potomac horse fever. Infection and Immunity, v. 49, n. 3, p. 513-517, 1985. RIKIHISA, Y.; PERRY, B.D.; CORDES, D.O. Ultraestructural study of ehrlichial organism in the large colons of ponies infected with Potomac horse fever. Infection and Immunity, v.49, p. 505-515, 1985. RIKIHISA, Y.; PERRY, B.D.; CORDES, D.O. Rickettsial link with acute equine diarrhea. Veterinary Record v.115, p.554, 1984. RISTIC, M. DAWSON, J.; HOLLAND, C.J. Susceptibility of dogs to infection with Ehrlichia risticii, causative agent of equine monocytic ehrlichiosis (Potomac Horse Fever). American Journal of Veterinary Research, v. 49, p. 1497, 1988. RISTIC, M.; HOLLAND, C.J.; DAWSON, J.E.; SESSIONS, J.; PALMER, J. Diagnosis of equine monocytic ehrlichiosis (Potomac horse fever) by indirect immunofluorescence. Journal of American Veterinary Medical Association, v.189, p.39?46, 1986. ROBL, M.G. Potomac Horse Fever: Closing in on an unknown killer. Veterinary Clinics of North America: Equine Practice, v.80, p. 49-58, 1985. SAMPAIO, I. B. M. Estat?stica aplicada ? experimenta??o animal. 2? ed. Belo Horizonte: Editora, FEPMVZ, 2002. 265 p. SHALM, O.W.; WEISS, D.J.; WARDROP, K.J. (eds.) Veterinary Hematology, 6th ed. Blackwell Publishing. Iowa, 2010. 1206p. SCHMIDTMANN, E.T.; RICE, R.M.; ROBL, M.G.; AZAD, A.F. Search for an arthropod vector of Ehrlichia risticii. In: PROCEEDINGS OF A SYMPOSIUM ON POTOMAC HORSE FEVER. Veterinary Learning Systems Co., Lousiville, Kentucky, p.9-16 (1988) SMITH, B. P. Tratado de Medicina Interna de Grandes Animais: 1.ed. S?o Paulo: Manole, 1993. 900p. SPEIRS, V. C. Exame Cl?nico de equinos. Porto Alegre: ed. Artmed, 1?ed.1999. 366p. VAN HEECKEREN A, RIKIHISA Y, PARK J et al: Tumor necrosis factor- , interleukin-1 and prostaglandin E2 production in murine peritoneal macrophages infected with Ehrlichia risticii, Infection and Immunity, v.61, p.4333, 1993. WEISS, E.; MULDER, J.W. The Rickettsias and Chlamydias. In: N.R. Krieg and J.G. Holt (Editors), Bergey?s Manual of Systematic Bacteriology. Vol.I. Williams and Wilkins, Baltimore, p.687-739, 1984. 36 WEISS, E.; DASCH, KANG, Y-H.; WESTFALL, H.N. Substrate utilization by Ehrlichia sennetsu and Ehrlichia risticii separated from host constituents by renografin gradient centrifugation. Journal of Bacteriology, v. 170, n.11, p.5012-5017, 1988. WHITLOCK, R.H.; PALMER, J.E.; BERSON, C.E.; ACLAND, H.M.; JENNY, L.A.; RISTIC, M. Potomac horse fever: clinical characteristics and diagnostic features. In: PROCEEDINGS 27TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION VETERINARY LABORATORY DIAGNOSTICIANS, p.103-124, 1984. WILSON, J.H.; PUSTERLA, N.; BENGFORT, J.M.; ARNEY, L. Incrimination of Mayflies as a Vector of Potomac Horse Fever in an Outbreak in Minnesota. In: PROCEEDINGS 52th ANNUAL CONFERENCE EQUINE PRACTITIONERS, San Diego, CA. American Association of Equine Practitioners, v.52, p. 324-326, 1989 WOESE, C.R.; KANDLER, O.; WHEELIS, M. Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eukarya. Proc Natl Acad Sci USA, v.87, p. 4576-4579, 1990. ZIEMER, L.E.; WHITLOCK, R.H.; PALMER, J.E.; SPENCER, P.A. Clinical and hematological variables in ponies with experimental induced equine ehrlichial colitis (Potomac horse fever). American Journal Veterinary Research, v.48, p.63-67, 1987.Neorickettsia risticiiEhrlichiosis Monocytic EquineHorsesEpidemiology.Erliquiose Monoc?tica EquinaEquinosEpidemiologia.Medicina Veterin?riaNeorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de JaneiroNeorickettsia risticii: clinical, hematological, serological and molecular techniques in horses in the microregion of Itaguai, Rio de Janeiroinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFRRJinstname:Universidade Federal Rural do Rio de Janeiro (UFRRJ)instacron:UFRRJTHUMBNAIL2011 - Erica Cristina Rocha Roier.pdf.jpg2011 - Erica Cristina Rocha Roier.pdf.jpgimage/jpeg3938http://localhost:8080/tede/bitstream/jspui/1223/18/2011+-+Erica+Cristina+Rocha+Roier.pdf.jpg9c08a35468950e4081c486016c294400MD518TEXT2011 - Erica Cristina Rocha Roier.pdf.txt2011 - Erica Cristina Rocha Roier.pdf.txttext/plain138318http://localhost:8080/tede/bitstream/jspui/1223/17/2011+-+Erica+Cristina+Rocha+Roier.pdf.txtf0e66eb469521afa60bd715c990d862eMD517ORIGINAL2011 - Erica Cristina Rocha Roier.pdf2011 - Erica Cristina Rocha Roier.pdfapplication/pdf982721http://localhost:8080/tede/bitstream/jspui/1223/2/2011+-+Erica+Cristina+Rocha+Roier.pdf24c0654d64de8a5b21a0eea5376f828cMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82089http://localhost:8080/tede/bitstream/jspui/1223/1/license.txt7b5ba3d2445355f386edab96125d42b7MD51jspui/12232023-02-19 21:59:32.499oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttps://tede.ufrrj.br/PUBhttps://tede.ufrrj.br/oai/requestbibliot@ufrrj.br||bibliot@ufrrj.bropendoar:2023-02-19T23:59:32Biblioteca Digital de Teses e Dissertações da UFRRJ - Universidade Federal Rural do Rio de Janeiro (UFRRJ)false |
dc.title.por.fl_str_mv |
Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro |
dc.title.alternative.eng.fl_str_mv |
Neorickettsia risticii: clinical, hematological, serological and molecular techniques in horses in the microregion of Itaguai, Rio de Janeiro |
title |
Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro |
spellingShingle |
Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro Roier, Erica Cristina Rocha Neorickettsia risticii Ehrlichiosis Monocytic Equine Horses Epidemiology. Erliquiose Monoc?tica Equina Equinos Epidemiologia. Medicina Veterin?ria |
title_short |
Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro |
title_full |
Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro |
title_fullStr |
Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro |
title_full_unstemmed |
Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro |
title_sort |
Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro |
author |
Roier, Erica Cristina Rocha |
author_facet |
Roier, Erica Cristina Rocha |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Massard, Carlos Luiz |
dc.contributor.advisor1ID.fl_str_mv |
257.781.297-34 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/7743112049924654 |
dc.contributor.advisor-co1.fl_str_mv |
Baldani, Cristiane Divan |
dc.contributor.advisor-co1ID.fl_str_mv |
044.128.097-81 |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/6210245465538447 |
dc.contributor.referee1.fl_str_mv |
Leite, Rom?rio Cerqueira |
dc.contributor.referee2.fl_str_mv |
Linhares, Guido Fontgalland Coelho |
dc.contributor.referee3.fl_str_mv |
Barreira, Jairo Dias |
dc.contributor.referee4.fl_str_mv |
Grisi, Laerte |
dc.contributor.authorID.fl_str_mv |
023.688.377-10 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/3538932429235543 |
dc.contributor.author.fl_str_mv |
Roier, Erica Cristina Rocha |
contributor_str_mv |
Massard, Carlos Luiz Baldani, Cristiane Divan Leite, Rom?rio Cerqueira Linhares, Guido Fontgalland Coelho Barreira, Jairo Dias Grisi, Laerte |
dc.subject.eng.fl_str_mv |
Neorickettsia risticii Ehrlichiosis Monocytic Equine Horses Epidemiology. |
topic |
Neorickettsia risticii Ehrlichiosis Monocytic Equine Horses Epidemiology. Erliquiose Monoc?tica Equina Equinos Epidemiologia. Medicina Veterin?ria |
dc.subject.por.fl_str_mv |
Erliquiose Monoc?tica Equina Equinos Epidemiologia. |
dc.subject.cnpq.fl_str_mv |
Medicina Veterin?ria |
description |
This study aimed to evaluate the prevalence of antibodies against Neorickettsia risticii in horses in the microregion of Itagua? RJ, show possible associated factors and identify the agent by molecular techniques. The study was conducted in the districts of Serop?dica, Itagua? and Mangaratiba, Rio de Janeiro. The 350 blood samples were obtained by convenience from horse properties belonging to the region. Serologic testing was performed by Immunofluorescence Assay (IFAI) for N. risticii, being considered positive samples titer 1:50. To evaluate risk factors associated with the presence of antibodies to N. risticii an epidemiological questionnaire was applied to the owners or guardians of animals, which aimed especially farm characteristics and management of animals. Hematological and clinical evaluation was performed for all animals. Molecular analysis by a Real Time PCR was performed from leukocyte cover. The prevalence of antibodies anti-N.risticii in horses of the region of Itagua? was 26.3% (92/350). The frequencies of IgG anti-N.rristicii were 52.2% (48/92) for titers of 1:50, zero for titers of 1:100, 13% (12/92) for titles of 1:200, 28.3% (26/92) for evidence of 1:400 and 6.5% (6 / 92) for titles of 1:800. The age and quality level of the properties were associated (p <0.05) with horses seropositivity for N. risticii. DNA from N. risticii was not detectable in samples of this study. Also no significant changes in the clinical evaluation of animals was found in relation to seropositivity for the agent. Despite showing association (p <0.05) between the seropositivity of the animals and changes in white blood cell of negative animals, these changes were not outside reference limits for the species evaluated. The existence of horses seropositive for N. risticii indicates the presence of this agent in the microregion of Itagua?. |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011-02-28 |
dc.date.accessioned.fl_str_mv |
2016-09-28T14:27:47Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ROIER, Erica Cristina Rocha. Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro. 2011. 43 f. Tese (Mestrado em Ci?ncias Veterin?rias) - Instituto de Veterin?ria, Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2011. |
dc.identifier.uri.fl_str_mv |
https://tede.ufrrj.br/jspui/handle/jspui/1223 |
identifier_str_mv |
ROIER, Erica Cristina Rocha. Neorickettsia risticii: aspectos cl?nicos, hematol?gicos, sorol?gicos e moleculares em equinos na microrregi?o de Itagua?, Rio de Janeiro. 2011. 43 f. Tese (Mestrado em Ci?ncias Veterin?rias) - Instituto de Veterin?ria, Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2011. |
url |
https://tede.ufrrj.br/jspui/handle/jspui/1223 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.references.por.fl_str_mv |
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