Detalhes bibliográficos
| Autor(a) principal: |
Andriotti, Paula Azevedo |
| Data de Publicação: |
2020 |
| Tipo de documento: |
Dissertação
|
| Idioma: |
por |
| Título da fonte: |
Biblioteca Digital de Teses e Dissertações da UFRRJ |
| Texto Completo: |
https://tede.ufrrj.br/jspui/handle/jspui/6319
|
Resumo: |
Lesions caused by breeds are quite uncomfortable and painful for dogs, and can cause secondary bacterial infections and predispose to other myiasis. Effective treatment should eliminate or kill existing larvae and promote wound healing as early as possible. However, currently, the recommended treatment for this parasite consists of manual removal of the larvae, which causes a lot of discomfort for the parasitized animal, so much so that, in some cases, there is a need for sedation to perform the procedure. The aim of this study was to evaluate the bernicidal efficacy of sarolaner for the treatment of Dermatobia hominis in naturally infested dogs. Ten mongrel dogs were included, aged between one and ten years, regardless of the sex variable, weighing between 11.4 and 19.1 kg, with at least three larvae. In total 75 larvae were counted, with an average of 7.5 larvae per animal. Most of the parasitism (46 larvae) was located in the lateral region of the animals. The animals were medicated with sarolaner at a dose of 2.0 mg / kg, administered orally in a single dose, following the recommendations in the package insert for the treatment of other ectoparasitoses. After treatment, the animals were kept in their homes and observations were made to verify the elimination activity and the bernicidal effect of the drug after 24 hours of medication administration. Any parasite that showed motility after mechanical removal was considered a live larva. As criteria for assessing the efficacy of sarolaner, the larvicidal effect was calculated for each animal using the formula: [Number of live larvae after treatment - number of live larvae before treatment) / Number of live larvae before treatment] ? 100. After 24 hours after medication administration, all larvae were found dead, although located in the animals' dermis. No animal had an adverse effect or behavior change after using isoxazoline. It is concluded that sarolaner administered in a single dose of 2.0mg / kg, orally, was 100% effective in dogs naturally infested by D. hominis. |