Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFS |
| Texto Completo: | http://online.liebertpub.com/doi/full/10.1089/jmf.2010.0125 https://ri.ufs.br/handle/riufs/620 |
Resumo: | This is a copy of an article published in the Journal of Medicinal Food© 2011 - copyright Mary Ann Liebert, Inc.; Journal of Medicinal Food is available online at: http://online.liebertpub.com |
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Quintans-Júnior, Lucindo JoséRocha, Ricardo Fagundes daCaregnato, Fernanda FreitasMoreira, José Cláudio FonsecaSilva, Francilene Amaral daAraújo, Adriano Antunes de SouzaSantos, João Paulo Almeida dosMelo, Mônica Santos deSousa, Damião Pergentino deBonjardim, Leonardo RigoldiGelain, Daniel Pens2013-06-21T23:40:05Z2013-06-21T23:40:05Z2011-05QUINTANS-JÚNIOR, L. J. et al. Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass. Journal of Medicinal Food, San Diego, v. 14, n. 6, p. 630-639, maio 2011. Disponível em: <http://online.liebertpub.com/doi/full/10.1089/jmf.2010.0125>. Acesso em: 21 jun. 2013.1557-7600http://online.liebertpub.com/doi/full/10.1089/jmf.2010.0125https://ri.ufs.br/handle/riufs/620Mary Ann Liebert, Inc.This is a copy of an article published in the Journal of Medicinal Food© 2011 - copyright Mary Ann Liebert, Inc.; Journal of Medicinal Food is available online at: http://online.liebertpub.comCitronellal (CT) is a monoterpenoid and the major constituent of the mixture of terpenoids that give the citronella oil its lemon scent. Citronella oil is widely used around the world for various purposes and is mainly obtained from plants of the Cymbopogon genus, which are known as “lemongrass.” Considering these plants have been used worldwide for various medicinal purposes, the interest of researchers to understand the biological activities of monoterpenoids related to the Cymbopogon genus has been increasing. In the present work, we investigated the antinociceptive action and the redox properties of CT. Our results indicate that intraperitoneal injection of CT was effective in reducing nociceptive face-rubbing behavior in both phases of the formalin test, which was also naloxone-sensitive. CT also evoked antinociceptive response in the capsaicin and glutamate tests. The total radical-trapping antioxidant parameter and total antioxidant reactivity assays indicate that CT at doses of 0.1 and 1 mg/mL exerts a significant antioxidant activity, which is probably related to its ability to scavenge superoxide and nitric oxide, but not H2O2 or hydroxyl radicals, as evaluated separately by specific in vitro tests. These results show for the first time the antinociceptive potential of CT and indicate that the antioxidant properties of this compound may rely on its mechanism of biological actions because CT-containing natural products are used to treat various diseases related to oxidative stress and reactive species.Mary Ann Liebert, Inc.Atividade antinociceptivaPropriedades redoxCitronelaÓleos essenciaisCapim-limãoAntinociceptive action and redox properties of citronellal, an essential oil present in lemongrassinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILAntinociceptiveActionLemongrass.pdf.jpgAntinociceptiveActionLemongrass.pdf.jpgGenerated Thumbnailimage/jpeg1641https://ri.ufs.br/jspui/bitstream/riufs/620/4/AntinociceptiveActionLemongrass.pdf.jpg0539cb0f465aef1ef182f5fe58da0a28MD54ORIGINALAntinociceptiveActionLemongrass.pdfAntinociceptiveActionLemongrass.pdfapplication/pdf390329https://ri.ufs.br/jspui/bitstream/riufs/620/1/AntinociceptiveActionLemongrass.pdff090cebfac018f38e5fd7494a55ed4cbMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/620/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTAntinociceptiveActionLemongrass.pdf.txtAntinociceptiveActionLemongrass.pdf.txtExtracted texttext/plain48561https://ri.ufs.br/jspui/bitstream/riufs/620/3/AntinociceptiveActionLemongrass.pdf.txt0a99654e360b52ec08d5678af934c7abMD53riufs/6202013-12-20 16:50:18.741oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2013-12-20T19:50:18Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
| dc.title.pt_BR.fl_str_mv |
Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass |
| title |
Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass |
| spellingShingle |
Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass Quintans-Júnior, Lucindo José Atividade antinociceptiva Propriedades redox Citronela Óleos essenciais Capim-limão |
| title_short |
Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass |
| title_full |
Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass |
| title_fullStr |
Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass |
| title_full_unstemmed |
Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass |
| title_sort |
Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass |
| author |
Quintans-Júnior, Lucindo José |
| author_facet |
Quintans-Júnior, Lucindo José Rocha, Ricardo Fagundes da Caregnato, Fernanda Freitas Moreira, José Cláudio Fonseca Silva, Francilene Amaral da Araújo, Adriano Antunes de Souza Santos, João Paulo Almeida dos Melo, Mônica Santos de Sousa, Damião Pergentino de Bonjardim, Leonardo Rigoldi Gelain, Daniel Pens |
| author_role |
author |
| author2 |
Rocha, Ricardo Fagundes da Caregnato, Fernanda Freitas Moreira, José Cláudio Fonseca Silva, Francilene Amaral da Araújo, Adriano Antunes de Souza Santos, João Paulo Almeida dos Melo, Mônica Santos de Sousa, Damião Pergentino de Bonjardim, Leonardo Rigoldi Gelain, Daniel Pens |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Quintans-Júnior, Lucindo José Rocha, Ricardo Fagundes da Caregnato, Fernanda Freitas Moreira, José Cláudio Fonseca Silva, Francilene Amaral da Araújo, Adriano Antunes de Souza Santos, João Paulo Almeida dos Melo, Mônica Santos de Sousa, Damião Pergentino de Bonjardim, Leonardo Rigoldi Gelain, Daniel Pens |
| dc.subject.por.fl_str_mv |
Atividade antinociceptiva Propriedades redox Citronela Óleos essenciais Capim-limão |
| topic |
Atividade antinociceptiva Propriedades redox Citronela Óleos essenciais Capim-limão |
| description |
This is a copy of an article published in the Journal of Medicinal Food© 2011 - copyright Mary Ann Liebert, Inc.; Journal of Medicinal Food is available online at: http://online.liebertpub.com |
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2011 |
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2011-05 |
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2013-06-21T23:40:05Z |
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2013-06-21T23:40:05Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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QUINTANS-JÚNIOR, L. J. et al. Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass. Journal of Medicinal Food, San Diego, v. 14, n. 6, p. 630-639, maio 2011. Disponível em: <http://online.liebertpub.com/doi/full/10.1089/jmf.2010.0125>. Acesso em: 21 jun. 2013. |
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http://online.liebertpub.com/doi/full/10.1089/jmf.2010.0125 https://ri.ufs.br/handle/riufs/620 |
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1557-7600 |
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Mary Ann Liebert, Inc. |
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QUINTANS-JÚNIOR, L. J. et al. Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass. Journal of Medicinal Food, San Diego, v. 14, n. 6, p. 630-639, maio 2011. Disponível em: <http://online.liebertpub.com/doi/full/10.1089/jmf.2010.0125>. Acesso em: 21 jun. 2013. 1557-7600 Mary Ann Liebert, Inc. |
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Mary Ann Liebert, Inc. |
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Mary Ann Liebert, Inc. |
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