Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFS |
| Texto Completo: | https://ri.ufs.br/handle/riufs/594 |
Resumo: | This is a copy of an article published in the Journal of Medicinal Food© 2011 - copyright Mary Ann Liebert, Inc.; Journal of Medicinal Food is available online at: http://online.liebertpub.com |
| id |
UFS-2_4635993c47efb6ad8c4bfbf69e48877d |
|---|---|
| oai_identifier_str |
oai:ufs.br:riufs/594 |
| network_acronym_str |
UFS-2 |
| network_name_str |
Repositório Institucional da UFS |
| repository_id_str |
|
| spelling |
Serafini, Mairim RussoSantos, Rodrigo CorreiaGuimarães, Adriana GibaraSantos, João Paulo Almeida dosSantos, Alan Diego da ConceiçãoAlves, Izabel AlmeidaGelain, Daniel PensNogueira, Paulo Cesar de LimaQuintans-Júnior, Lucindo JoséBonjardim, Leonardo RigoldiAraújo, Adriano Antunes de Souza2013-06-08T00:00:38Z2013-06-08T00:00:38Z2011-10SERAFINI, M. R. et al. Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration. Journal of Medicinal Food, San Diego, v. 14, n. 10, out. 2011. Disponível em: <http://online.liebertpub.com/doi/abs/10.1089/jmf.2010.0254>. Acesso em: 7 jun. 2013.1557-7600https://ri.ufs.br/handle/riufs/594Copyright Mary Ann Liebert, Inc.This is a copy of an article published in the Journal of Medicinal Food© 2011 - copyright Mary Ann Liebert, Inc.; Journal of Medicinal Food is available online at: http://online.liebertpub.comHerbal drugs have been used since ancient times to treat a wide range of diseases. Morinda citrifolia Linn (popularly known as ‘‘Noni’’) has been used in folk medicine by Polynesians for over 2,000 years. It is reported to have a broad range of therapeutic effects, including effects against headache, fever, arthritis, gingivitis, respiratory disorders, infections, tuberculosis, and diabetes. The aim of this study was to investigate the antioxidant, anti-inflammatory, antinociceptive, and antibacterial properties of the aqueous extract from M. citrifolia leaves (AEMC). Antioxidant activity was observed against lipid peroxidation, nitric oxide, and hydroxyl radicals. The antinociceptive effect of AEMC was observed in the acetic acid–induced writhing test at the higher dose. Moreover, AEMC significantly reduced the leukocyte migration in doses of 200 and 400 mg/kg and showed mild antibacterial activity. Together, the results suggest that properties of M. citrifolia leaf extract should be explored further in order to achieve newer tools for managing painful and inflammation conditions, including those related to oxidant states.Mary Ann Liebert, Inc.Anti-inflamatórioAtividade antinociceptivaAtividade antioxidanteMorinda citrifoliaMorinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migrationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILMorindaCitrifoliaAntioxidant.pdf.jpgMorindaCitrifoliaAntioxidant.pdf.jpgGenerated Thumbnailimage/jpeg1699https://ri.ufs.br/jspui/bitstream/riufs/594/4/MorindaCitrifoliaAntioxidant.pdf.jpg8959b0a8cfb496417dacdafe5f505c21MD54ORIGINALMorindaCitrifoliaAntioxidant.pdfMorindaCitrifoliaAntioxidant.pdfapplication/pdf384278https://ri.ufs.br/jspui/bitstream/riufs/594/1/MorindaCitrifoliaAntioxidant.pdf77037ee385801cdea91f3a1c583c5de1MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/594/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTMorindaCitrifoliaAntioxidant.pdf.txtMorindaCitrifoliaAntioxidant.pdf.txtExtracted texttext/plain35229https://ri.ufs.br/jspui/bitstream/riufs/594/3/MorindaCitrifoliaAntioxidant.pdf.txt9eac1e75766b0279368580d0a1659532MD53riufs/5942013-06-11 20:46:52.882oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2013-06-11T23:46:52Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
| dc.title.pt_BR.fl_str_mv |
Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration |
| title |
Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration |
| spellingShingle |
Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration Serafini, Mairim Russo Anti-inflamatório Atividade antinociceptiva Atividade antioxidante Morinda citrifolia |
| title_short |
Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration |
| title_full |
Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration |
| title_fullStr |
Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration |
| title_full_unstemmed |
Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration |
| title_sort |
Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration |
| author |
Serafini, Mairim Russo |
| author_facet |
Serafini, Mairim Russo Santos, Rodrigo Correia Guimarães, Adriana Gibara Santos, João Paulo Almeida dos Santos, Alan Diego da Conceição Alves, Izabel Almeida Gelain, Daniel Pens Nogueira, Paulo Cesar de Lima Quintans-Júnior, Lucindo José Bonjardim, Leonardo Rigoldi Araújo, Adriano Antunes de Souza |
| author_role |
author |
| author2 |
Santos, Rodrigo Correia Guimarães, Adriana Gibara Santos, João Paulo Almeida dos Santos, Alan Diego da Conceição Alves, Izabel Almeida Gelain, Daniel Pens Nogueira, Paulo Cesar de Lima Quintans-Júnior, Lucindo José Bonjardim, Leonardo Rigoldi Araújo, Adriano Antunes de Souza |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Serafini, Mairim Russo Santos, Rodrigo Correia Guimarães, Adriana Gibara Santos, João Paulo Almeida dos Santos, Alan Diego da Conceição Alves, Izabel Almeida Gelain, Daniel Pens Nogueira, Paulo Cesar de Lima Quintans-Júnior, Lucindo José Bonjardim, Leonardo Rigoldi Araújo, Adriano Antunes de Souza |
| dc.subject.por.fl_str_mv |
Anti-inflamatório Atividade antinociceptiva Atividade antioxidante Morinda citrifolia |
| topic |
Anti-inflamatório Atividade antinociceptiva Atividade antioxidante Morinda citrifolia |
| description |
This is a copy of an article published in the Journal of Medicinal Food© 2011 - copyright Mary Ann Liebert, Inc.; Journal of Medicinal Food is available online at: http://online.liebertpub.com |
| publishDate |
2011 |
| dc.date.issued.fl_str_mv |
2011-10 |
| dc.date.accessioned.fl_str_mv |
2013-06-08T00:00:38Z |
| dc.date.available.fl_str_mv |
2013-06-08T00:00:38Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
SERAFINI, M. R. et al. Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration. Journal of Medicinal Food, San Diego, v. 14, n. 10, out. 2011. Disponível em: <http://online.liebertpub.com/doi/abs/10.1089/jmf.2010.0254>. Acesso em: 7 jun. 2013. |
| dc.identifier.uri.fl_str_mv |
https://ri.ufs.br/handle/riufs/594 |
| dc.identifier.issn.none.fl_str_mv |
1557-7600 |
| dc.identifier.license.pt_BR.fl_str_mv |
Copyright Mary Ann Liebert, Inc. |
| identifier_str_mv |
SERAFINI, M. R. et al. Morinda citrifolia linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration. Journal of Medicinal Food, San Diego, v. 14, n. 10, out. 2011. Disponível em: <http://online.liebertpub.com/doi/abs/10.1089/jmf.2010.0254>. Acesso em: 7 jun. 2013. 1557-7600 Copyright Mary Ann Liebert, Inc. |
| url |
https://ri.ufs.br/handle/riufs/594 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Mary Ann Liebert, Inc. |
| publisher.none.fl_str_mv |
Mary Ann Liebert, Inc. |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFS instname:Universidade Federal de Sergipe (UFS) instacron:UFS |
| instname_str |
Universidade Federal de Sergipe (UFS) |
| instacron_str |
UFS |
| institution |
UFS |
| reponame_str |
Repositório Institucional da UFS |
| collection |
Repositório Institucional da UFS |
| bitstream.url.fl_str_mv |
https://ri.ufs.br/jspui/bitstream/riufs/594/4/MorindaCitrifoliaAntioxidant.pdf.jpg https://ri.ufs.br/jspui/bitstream/riufs/594/1/MorindaCitrifoliaAntioxidant.pdf https://ri.ufs.br/jspui/bitstream/riufs/594/2/license.txt https://ri.ufs.br/jspui/bitstream/riufs/594/3/MorindaCitrifoliaAntioxidant.pdf.txt |
| bitstream.checksum.fl_str_mv |
8959b0a8cfb496417dacdafe5f505c21 77037ee385801cdea91f3a1c583c5de1 8a4605be74aa9ea9d79846c1fba20a33 9eac1e75766b0279368580d0a1659532 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS) |
| repository.mail.fl_str_mv |
repositorio@academico.ufs.br |
| _version_ |
1793350906264158208 |