Xeroderma pigmentoso: relato de caso
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | http://ri.ufs.br/jspui/handle/riufs/9301 |
Resumo: | Introduction: Xeroderma pigmentosum (XP) is a rare autosomal recessive disease, characterized by cutaneous hypersensitivity to ultraviolet radiation. The disease can cause cell mutations that result in changes in the skin, delayed cognitive functions and neuropsychomotor development. It also increases the risk of cancer and interferes with quality of life. Objective: This study aims to report the case of a patient with XP who presented aggressive skin tumor and required radical surgery with reconstruction with a regional musculocutaneous flap. Case Report: MMS, female, 33 years old, with XP, accompanied at the Oncology Service of Sergipe Emergency Hospital since May 2006, was submitted to treatment of tumor recurrence in the face of aggressive squamous cell carcinoma (SCC) with enlargement of the surgical margins and block parotidectomy associated with cervical emptying and reconstruction with platysma musculocutaneous flap. Conclusion: The radical surgical treatment with adequate margins associated with lymphadenectomy and reconstruction with a musculocutaneous flap were effective for the cure of cancer and prevented functional and aesthetic sequelae in this case of Xeroderma pigmentosum. |
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Dantas, Edcleverton BarrosAraújo, Fernando Vicente de2018-10-22T14:07:47Z2018-10-22T14:07:47Z2018-07-13DANTAS, Edcleverton Barros. Xeroderma pigmentoso: : relato de caso. 2018. 37 f. Monografia (Graduação em Medicina) - Universidade Federal de Sergipe, Lagarto, 2018.http://ri.ufs.br/jspui/handle/riufs/9301Introduction: Xeroderma pigmentosum (XP) is a rare autosomal recessive disease, characterized by cutaneous hypersensitivity to ultraviolet radiation. The disease can cause cell mutations that result in changes in the skin, delayed cognitive functions and neuropsychomotor development. It also increases the risk of cancer and interferes with quality of life. Objective: This study aims to report the case of a patient with XP who presented aggressive skin tumor and required radical surgery with reconstruction with a regional musculocutaneous flap. Case Report: MMS, female, 33 years old, with XP, accompanied at the Oncology Service of Sergipe Emergency Hospital since May 2006, was submitted to treatment of tumor recurrence in the face of aggressive squamous cell carcinoma (SCC) with enlargement of the surgical margins and block parotidectomy associated with cervical emptying and reconstruction with platysma musculocutaneous flap. Conclusion: The radical surgical treatment with adequate margins associated with lymphadenectomy and reconstruction with a musculocutaneous flap were effective for the cure of cancer and prevented functional and aesthetic sequelae in this case of Xeroderma pigmentosum.Introdução: Xeroderma pigmentoso (XP) é uma doença autossômica recessiva rara, caracterizada por uma hipersensibilidade cutânea à radiação ultravioleta. A doença pode causar mutações celulares que resultam em alterações na pele, atraso das funções cognitivas e no desenvolvimento neuropsicomotor. Além disso, aumenta o risco de câncer e interfere na qualidade de vida. Objetivo: Este trabalho visa relatar o caso de uma paciente com XP que apresentou tumor de pele de comportamento agressivo e necessitou de cirurgia radical com reconstrução com retalho regional musculocutâneo. Relato de Caso: MMS, gênero feminino, 33 anos, portadora de XP, acompanhada no Serviço de Oncologia do Hospital de Urgências de Sergipe desde maio de 2006, foi submetida a tratamento de recidiva tumoral em face por carcinoma espinocelular(CEC) agressivo com ampliação das margens cirúrgicas e parotidectomia em bloco associados a esvaziamento cervical e à reconstrução com retalho musculocutâneo de platisma. Conclusão: O tratamento cirúrgico radical com margens adequadas associado à linfadenectomia demonstrou ser eficiente para a cura do câncer de pele de comportamento altamente agressivo observado neste caso de Xeroderma pigmentoso. Além disso, a reconstrução com retalho musculocutâneo evitou sequelas funcionais e estéticas.Lagarto, SEporCarcinoma de células escamosasGlândulasDistúrbios de pigmentação da peleGlândula parótidaXeroderma pigmentosoXeroderma pigmentosumParotid glandSquamous cell CarcinomaXeroderma pigmentoso: relato de casoXeroderma pigmentosum: case reportinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUFSDMEL - Departamento de Medicina Lagarto – Lagarto - Presencialreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTEXTEDCLEVERTON_BARROS_DANTAS.pdf.txtEDCLEVERTON_BARROS_DANTAS.pdf.txtExtracted texttext/plain56242https://ri.ufs.br/jspui/bitstream/riufs/9301/3/EDCLEVERTON_BARROS_DANTAS.pdf.txtb4611af4cbd5e32279e7b970b0e214dbMD53THUMBNAILEDCLEVERTON_BARROS_DANTAS.pdf.jpgEDCLEVERTON_BARROS_DANTAS.pdf.jpgGenerated Thumbnailimage/jpeg1164https://ri.ufs.br/jspui/bitstream/riufs/9301/4/EDCLEVERTON_BARROS_DANTAS.pdf.jpg49be40d234be519a45a6e56046167495MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/9301/1/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD51ORIGINALEDCLEVERTON_BARROS_DANTAS.pdfEDCLEVERTON_BARROS_DANTAS.pdfapplication/pdf1262237https://ri.ufs.br/jspui/bitstream/riufs/9301/2/EDCLEVERTON_BARROS_DANTAS.pdfd45e4632eff0d8a5578f29f8cf52525cMD52riufs/93012018-10-22 11:07:47.918oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2018-10-22T14:07:47Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.pt_BR.fl_str_mv |
Xeroderma pigmentoso: relato de caso |
dc.title.alternative.eng.fl_str_mv |
Xeroderma pigmentosum: case report |
title |
Xeroderma pigmentoso: relato de caso |
spellingShingle |
Xeroderma pigmentoso: relato de caso Dantas, Edcleverton Barros Carcinoma de células escamosas Glândulas Distúrbios de pigmentação da pele Glândula parótida Xeroderma pigmentoso Xeroderma pigmentosum Parotid gland Squamous cell Carcinoma |
title_short |
Xeroderma pigmentoso: relato de caso |
title_full |
Xeroderma pigmentoso: relato de caso |
title_fullStr |
Xeroderma pigmentoso: relato de caso |
title_full_unstemmed |
Xeroderma pigmentoso: relato de caso |
title_sort |
Xeroderma pigmentoso: relato de caso |
author |
Dantas, Edcleverton Barros |
author_facet |
Dantas, Edcleverton Barros |
author_role |
author |
dc.contributor.author.fl_str_mv |
Dantas, Edcleverton Barros |
dc.contributor.advisor1.fl_str_mv |
Araújo, Fernando Vicente de |
contributor_str_mv |
Araújo, Fernando Vicente de |
dc.subject.por.fl_str_mv |
Carcinoma de células escamosas Glândulas Distúrbios de pigmentação da pele Glândula parótida Xeroderma pigmentoso |
topic |
Carcinoma de células escamosas Glândulas Distúrbios de pigmentação da pele Glândula parótida Xeroderma pigmentoso Xeroderma pigmentosum Parotid gland Squamous cell Carcinoma |
dc.subject.eng.fl_str_mv |
Xeroderma pigmentosum Parotid gland Squamous cell Carcinoma |
description |
Introduction: Xeroderma pigmentosum (XP) is a rare autosomal recessive disease, characterized by cutaneous hypersensitivity to ultraviolet radiation. The disease can cause cell mutations that result in changes in the skin, delayed cognitive functions and neuropsychomotor development. It also increases the risk of cancer and interferes with quality of life. Objective: This study aims to report the case of a patient with XP who presented aggressive skin tumor and required radical surgery with reconstruction with a regional musculocutaneous flap. Case Report: MMS, female, 33 years old, with XP, accompanied at the Oncology Service of Sergipe Emergency Hospital since May 2006, was submitted to treatment of tumor recurrence in the face of aggressive squamous cell carcinoma (SCC) with enlargement of the surgical margins and block parotidectomy associated with cervical emptying and reconstruction with platysma musculocutaneous flap. Conclusion: The radical surgical treatment with adequate margins associated with lymphadenectomy and reconstruction with a musculocutaneous flap were effective for the cure of cancer and prevented functional and aesthetic sequelae in this case of Xeroderma pigmentosum. |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-10-22T14:07:47Z |
dc.date.available.fl_str_mv |
2018-10-22T14:07:47Z |
dc.date.issued.fl_str_mv |
2018-07-13 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/bachelorThesis |
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bachelorThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
DANTAS, Edcleverton Barros. Xeroderma pigmentoso: : relato de caso. 2018. 37 f. Monografia (Graduação em Medicina) - Universidade Federal de Sergipe, Lagarto, 2018. |
dc.identifier.uri.fl_str_mv |
http://ri.ufs.br/jspui/handle/riufs/9301 |
identifier_str_mv |
DANTAS, Edcleverton Barros. Xeroderma pigmentoso: : relato de caso. 2018. 37 f. Monografia (Graduação em Medicina) - Universidade Federal de Sergipe, Lagarto, 2018. |
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http://ri.ufs.br/jspui/handle/riufs/9301 |
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DMEL - Departamento de Medicina Lagarto – Lagarto - Presencial |
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