Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence

Detalhes bibliográficos
Autor(a) principal: Sousa, Antônio Carlos Sobral
Data de Publicação: 2007
Outros Autores: Oliveira, Joselina Luzia Menezes, Goes, Thiago Jônatas Santos, Santana, Thaiana Aragão, Silva, Isabela Souza, Travassos, Thiago Figueiredo, Teles, Lívia Dantas, Barreto, Martha Azevedo, Barreto Filho, José Augusto Soares
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/handle/riufs/1285
Resumo: FUNDAMENTO: A incompetência cronotrópica (ICT) é freqüente em pacientes idosos e pode limitar o papel do teste ergométrico na identificação da doença arterial coronariana (DAC) nessa população. OBJETIVO: Avaliar o valor da ICT, em uma população idosa, no diagnóstico da DAC. MÉTODOS: Foram estudados 3.308 pacientes, desses, 804 eram idosos (idade >65 anos) que se submeteram a ecocardiografia sob estresse pelo esforço físico (EEEF). Com base na freqüência cardíaca (FC) alcançada durante o teste ergométrico, subdivididos em dois grupos: G1 – 150 pacientes que não atingiram 85% da FC preconizada para a idade e G2 – 654 pacientes que conseguiram atingir. Os grupos foram comparados quanto a características clínicas, índice de contratilidade segmentar do ventrículo esquerdo (IMVE) e cineangiocoronariografia (CACG). RESULTADOS: As características clínicas foram similares entre os grupos. O IMVE foi maior em G1 do que em G2, tanto no repouso (1.09 ± 0.21 versus 1.04 ± 0,15) quanto após esforço (1.15 ± 0.29 versus 1.08 ± 0.2) (p < 0,001). As anormalidades na contratilidade das paredes foram mais freqüentes em G1 do que em G2 (55% versus 37%; p < 0,05), sugerindo que pacientes idosos com ICT apresentam maior freqüência de DAC. Realizou-se CACG em 69% das EEEF positiva para isquemia miocárdica. No G1, 91% dos pacientes com EEEF positivo para isquemia realmente eram portadores doença obstrutiva arterial coronariana (>50%) versus 84,5% em G2. CONCLUSÃO: A ICT está associada à maior freqüência de alterações contráteis em população idosa e adiciona valor preditivo positivo à EEEF ao identificar pacientes com DAC obstrutiva. _________________________________________________________________________________________ ABSTRACT: BACKGROUND: Chronotropic incompetence (CTI) is frequent in elderly patients and may limit the role of the exercise test in the identification of coronary artery disease (CAD) in this population. OBJECTIVE: To assess the value of CTI in an elderly population in the diagnosis of CAD. METHODS: A total of 3,308 patients were studied, 804 were elderly individuals (age > 65 years) who underwent exercise stress echocardiography (ESE). Based on the heart rate (HR) reached during the exercise test, were divided into two groups: G1 150 patients who did not reach 85% of the age-predicted HR, and G2 654 patients who did. The groups were compared to clinical characteristics, segmental left ventricular contractility rate (WMSI) and coronary angiography (CAG). RESULTS: Clinical characteristics were similar between the groups. WMSI was higher in G1 than in G2, both at rest (1.09 ± 0.21 versus 1.04 ± 0.15) and after exercise (1.15 ± 0.29 versus 1.08 ± 0.2) (p < 0.001). Abnormalities in wall contractility were more frequent in G1 than in G2 (55% versus 37%; p < 0.05), thus suggesting that elderly with CTI have a higher frequency of CAD. CAG was performed in 69% ESE positive for myocardial ischemia. In the G1 group, 91% of the ESE were true positive versus 84.5% in G2, that is, presence of obstructive coronary artery disease (> 50%). CONCLUSION: CTI is associated with a higher frequency of contractile alterations in the elderly population and adds a positive predictive value to ESE in the identification of patients with obstructive CAD.
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spelling Sousa, Antônio Carlos SobralOliveira, Joselina Luzia MenezesGoes, Thiago Jônatas SantosSantana, Thaiana AragãoSilva, Isabela SouzaTravassos, Thiago FigueiredoTeles, Lívia DantasBarreto, Martha AzevedoBarreto Filho, José Augusto Soares2014-10-03T17:44:56Z2014-10-03T17:44:56Z2007-08OLIVEIRA, J. L. M. et. al. Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence. Arquivos Brasileiros de Cardiologia, São Paulo, v. 89, n. 2, ago. 2007. Disponível em: <http://dx.doi.org/10.1590/S0066-782X2007001400007>. Acesso em: 03 out. 2014.0066-782Xhttps://ri.ufs.br/handle/riufs/1285Creative Commons LicenseFUNDAMENTO: A incompetência cronotrópica (ICT) é freqüente em pacientes idosos e pode limitar o papel do teste ergométrico na identificação da doença arterial coronariana (DAC) nessa população. OBJETIVO: Avaliar o valor da ICT, em uma população idosa, no diagnóstico da DAC. MÉTODOS: Foram estudados 3.308 pacientes, desses, 804 eram idosos (idade >65 anos) que se submeteram a ecocardiografia sob estresse pelo esforço físico (EEEF). Com base na freqüência cardíaca (FC) alcançada durante o teste ergométrico, subdivididos em dois grupos: G1 – 150 pacientes que não atingiram 85% da FC preconizada para a idade e G2 – 654 pacientes que conseguiram atingir. Os grupos foram comparados quanto a características clínicas, índice de contratilidade segmentar do ventrículo esquerdo (IMVE) e cineangiocoronariografia (CACG). RESULTADOS: As características clínicas foram similares entre os grupos. O IMVE foi maior em G1 do que em G2, tanto no repouso (1.09 ± 0.21 versus 1.04 ± 0,15) quanto após esforço (1.15 ± 0.29 versus 1.08 ± 0.2) (p < 0,001). As anormalidades na contratilidade das paredes foram mais freqüentes em G1 do que em G2 (55% versus 37%; p < 0,05), sugerindo que pacientes idosos com ICT apresentam maior freqüência de DAC. Realizou-se CACG em 69% das EEEF positiva para isquemia miocárdica. No G1, 91% dos pacientes com EEEF positivo para isquemia realmente eram portadores doença obstrutiva arterial coronariana (>50%) versus 84,5% em G2. CONCLUSÃO: A ICT está associada à maior freqüência de alterações contráteis em população idosa e adiciona valor preditivo positivo à EEEF ao identificar pacientes com DAC obstrutiva. _________________________________________________________________________________________ ABSTRACT: BACKGROUND: Chronotropic incompetence (CTI) is frequent in elderly patients and may limit the role of the exercise test in the identification of coronary artery disease (CAD) in this population. OBJECTIVE: To assess the value of CTI in an elderly population in the diagnosis of CAD. METHODS: A total of 3,308 patients were studied, 804 were elderly individuals (age > 65 years) who underwent exercise stress echocardiography (ESE). Based on the heart rate (HR) reached during the exercise test, were divided into two groups: G1 150 patients who did not reach 85% of the age-predicted HR, and G2 654 patients who did. The groups were compared to clinical characteristics, segmental left ventricular contractility rate (WMSI) and coronary angiography (CAG). RESULTS: Clinical characteristics were similar between the groups. WMSI was higher in G1 than in G2, both at rest (1.09 ± 0.21 versus 1.04 ± 0.15) and after exercise (1.15 ± 0.29 versus 1.08 ± 0.2) (p < 0.001). Abnormalities in wall contractility were more frequent in G1 than in G2 (55% versus 37%; p < 0.05), thus suggesting that elderly with CTI have a higher frequency of CAD. CAG was performed in 69% ESE positive for myocardial ischemia. In the G1 group, 91% of the ESE were true positive versus 84.5% in G2, that is, presence of obstructive coronary artery disease (> 50%). CONCLUSION: CTI is associated with a higher frequency of contractile alterations in the elderly population and adds a positive predictive value to ESE in the identification of patients with obstructive CAD.Arquivos Brasileiros de CardiologiaEcocardiografiaIncompetência cronotrópicaIdosoCoronariopatiaExercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetenceEcocardiografia sob estresse físico na identificação de doença arterial coronariana em idosos com incompetência cronotrópicainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILExerciseStress.pdf.jpgExerciseStress.pdf.jpgGenerated Thumbnailimage/jpeg1567https://ri.ufs.br/jspui/bitstream/riufs/1285/4/ExerciseStress.pdf.jpg6dfca150357ff8fef5ea1341e28e02c6MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1285/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALExerciseStress.pdfExerciseStress.pdfapplication/pdf239590https://ri.ufs.br/jspui/bitstream/riufs/1285/1/ExerciseStress.pdf0819f93d52c65c60aab05ab53586b1e7MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1285/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTExerciseStress.pdf.txtExerciseStress.pdf.txtExtracted texttext/plain32117https://ri.ufs.br/jspui/bitstream/riufs/1285/3/ExerciseStress.pdf.txt05e574ca0b2af91c5785f63e08ada149MD53riufs/12852016-01-14 18:11:59.244oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2016-01-14T21:11:59Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence
dc.title.alternative.pt_BR.fl_str_mv Ecocardiografia sob estresse físico na identificação de doença arterial coronariana em idosos com incompetência cronotrópica
title Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence
spellingShingle Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence
Sousa, Antônio Carlos Sobral
Ecocardiografia
Incompetência cronotrópica
Idoso
Coronariopatia
title_short Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence
title_full Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence
title_fullStr Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence
title_full_unstemmed Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence
title_sort Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence
author Sousa, Antônio Carlos Sobral
author_facet Sousa, Antônio Carlos Sobral
Oliveira, Joselina Luzia Menezes
Goes, Thiago Jônatas Santos
Santana, Thaiana Aragão
Silva, Isabela Souza
Travassos, Thiago Figueiredo
Teles, Lívia Dantas
Barreto, Martha Azevedo
Barreto Filho, José Augusto Soares
author_role author
author2 Oliveira, Joselina Luzia Menezes
Goes, Thiago Jônatas Santos
Santana, Thaiana Aragão
Silva, Isabela Souza
Travassos, Thiago Figueiredo
Teles, Lívia Dantas
Barreto, Martha Azevedo
Barreto Filho, José Augusto Soares
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sousa, Antônio Carlos Sobral
Oliveira, Joselina Luzia Menezes
Goes, Thiago Jônatas Santos
Santana, Thaiana Aragão
Silva, Isabela Souza
Travassos, Thiago Figueiredo
Teles, Lívia Dantas
Barreto, Martha Azevedo
Barreto Filho, José Augusto Soares
dc.subject.por.fl_str_mv Ecocardiografia
Incompetência cronotrópica
Idoso
Coronariopatia
topic Ecocardiografia
Incompetência cronotrópica
Idoso
Coronariopatia
description FUNDAMENTO: A incompetência cronotrópica (ICT) é freqüente em pacientes idosos e pode limitar o papel do teste ergométrico na identificação da doença arterial coronariana (DAC) nessa população. OBJETIVO: Avaliar o valor da ICT, em uma população idosa, no diagnóstico da DAC. MÉTODOS: Foram estudados 3.308 pacientes, desses, 804 eram idosos (idade >65 anos) que se submeteram a ecocardiografia sob estresse pelo esforço físico (EEEF). Com base na freqüência cardíaca (FC) alcançada durante o teste ergométrico, subdivididos em dois grupos: G1 – 150 pacientes que não atingiram 85% da FC preconizada para a idade e G2 – 654 pacientes que conseguiram atingir. Os grupos foram comparados quanto a características clínicas, índice de contratilidade segmentar do ventrículo esquerdo (IMVE) e cineangiocoronariografia (CACG). RESULTADOS: As características clínicas foram similares entre os grupos. O IMVE foi maior em G1 do que em G2, tanto no repouso (1.09 ± 0.21 versus 1.04 ± 0,15) quanto após esforço (1.15 ± 0.29 versus 1.08 ± 0.2) (p < 0,001). As anormalidades na contratilidade das paredes foram mais freqüentes em G1 do que em G2 (55% versus 37%; p < 0,05), sugerindo que pacientes idosos com ICT apresentam maior freqüência de DAC. Realizou-se CACG em 69% das EEEF positiva para isquemia miocárdica. No G1, 91% dos pacientes com EEEF positivo para isquemia realmente eram portadores doença obstrutiva arterial coronariana (>50%) versus 84,5% em G2. CONCLUSÃO: A ICT está associada à maior freqüência de alterações contráteis em população idosa e adiciona valor preditivo positivo à EEEF ao identificar pacientes com DAC obstrutiva. _________________________________________________________________________________________ ABSTRACT: BACKGROUND: Chronotropic incompetence (CTI) is frequent in elderly patients and may limit the role of the exercise test in the identification of coronary artery disease (CAD) in this population. OBJECTIVE: To assess the value of CTI in an elderly population in the diagnosis of CAD. METHODS: A total of 3,308 patients were studied, 804 were elderly individuals (age > 65 years) who underwent exercise stress echocardiography (ESE). Based on the heart rate (HR) reached during the exercise test, were divided into two groups: G1 150 patients who did not reach 85% of the age-predicted HR, and G2 654 patients who did. The groups were compared to clinical characteristics, segmental left ventricular contractility rate (WMSI) and coronary angiography (CAG). RESULTS: Clinical characteristics were similar between the groups. WMSI was higher in G1 than in G2, both at rest (1.09 ± 0.21 versus 1.04 ± 0.15) and after exercise (1.15 ± 0.29 versus 1.08 ± 0.2) (p < 0.001). Abnormalities in wall contractility were more frequent in G1 than in G2 (55% versus 37%; p < 0.05), thus suggesting that elderly with CTI have a higher frequency of CAD. CAG was performed in 69% ESE positive for myocardial ischemia. In the G1 group, 91% of the ESE were true positive versus 84.5% in G2, that is, presence of obstructive coronary artery disease (> 50%). CONCLUSION: CTI is associated with a higher frequency of contractile alterations in the elderly population and adds a positive predictive value to ESE in the identification of patients with obstructive CAD.
publishDate 2007
dc.date.issued.fl_str_mv 2007-08
dc.date.accessioned.fl_str_mv 2014-10-03T17:44:56Z
dc.date.available.fl_str_mv 2014-10-03T17:44:56Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, J. L. M. et. al. Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence. Arquivos Brasileiros de Cardiologia, São Paulo, v. 89, n. 2, ago. 2007. Disponível em: <http://dx.doi.org/10.1590/S0066-782X2007001400007>. Acesso em: 03 out. 2014.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/handle/riufs/1285
dc.identifier.issn.none.fl_str_mv 0066-782X
dc.identifier.license.pt_BR.fl_str_mv Creative Commons License
identifier_str_mv OLIVEIRA, J. L. M. et. al. Exercise stress echocardiography in the identification of coronary artery disease in the elderly with chronotropic incompetence. Arquivos Brasileiros de Cardiologia, São Paulo, v. 89, n. 2, ago. 2007. Disponível em: <http://dx.doi.org/10.1590/S0066-782X2007001400007>. Acesso em: 03 out. 2014.
0066-782X
Creative Commons License
url https://ri.ufs.br/handle/riufs/1285
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Arquivos Brasileiros de Cardiologia
publisher.none.fl_str_mv Arquivos Brasileiros de Cardiologia
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reponame_str Repositório Institucional da UFS
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