Action of the gel Anacardium Occidentale L. associated with therapeutic ultrasound in the healing process in mice

• Autor(a) principal: Furtado, Renata Andressa Alves
• Data de Publicação: 2019
• Outros Autores: Noleto, Manoela Laís Pereira, Pessoa, Diego Rodrigues, Almeida, Vaniele da Silva, Maia Filho, Antônio Luiz Martins, Uchôa, Valdiléia Teixeira, Alves, Wellington dos Santos
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Saúde (Santa Maria)
• Texto Completo: https://periodicos.ufsm.br/revistasaude/article/view/35474
• topic: Terapia por Ultrassom; Medicamentos Fitoterápicos; Cicatrização de Feridas

INTRODUCTION: Physical therapy resources positively influence the healing process, accelerating the different phases and reducing the time of injury through the application of electrophysical resources, such as therapeutic ultrasound (TUS). The interaction between TUS and biological tissues is capable of generating cellular changes by mechanical effects, ensuring satisfactory results. Studies based on plant extracts have been carried out to prove effective alternative therapies capable of inducing wound healing, since medicinal plants, when compared to modern drug therapies, have lower adverse effects and lower cost when compared to synthetic drugs, essential for acquisition for the low-income population. OBJECTIVE: To evaluate the associated effect between cashew bark gel (Anacardium occidentale L) and therapeutic ultrasound on the healing process of skin wounds in mice. METHODOLOGY: 24 male (Mus musculus) mice weighing 40 to 50 grams (g) from the Faculty of Medical Sciences (FACIME) were used in this study. The research consisted of 4 groups (control, pulsed ultrasound + phonorosis, Anacardium occidentale L bark gel and pulsed ultrasound), which were treated at different experimental times (8 and 15 days). RESULTS: It was observed that both histological and macroscopic analysis showed improvement of the initial inflammatory process and acceleration of tissue repair in the groups treated with UST, extract, as well as through their interaction. CONCLUSION: It is concluded that the therapies used in the present study presented satisfactory results on the tissue repair process, which were confirmed by macroscopic and histological analysis.