Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting

Detalhes bibliográficos
Autor(a) principal: Binkowski, Raquel Trautenmüller Kerber
Data de Publicação: 2018
Outros Autores: Silveira, Ana Ligia da Silva, Sityá, Camila Santos, Haeffner, Léris Salete Bonfanti, Weinmann, Angela Regina Maciel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Saúde (Santa Maria)
Texto Completo: https://periodicos.ufsm.br/revistasaude/article/view/21284
Resumo: Therapeutic hypothermia is the standard clinical practice for neonates with moderate to severe hypoxic ischaemic encephalopathy (HIE). Aim: To implement a therapeutic hypothermia protocol using axillary temperature in newborns with HIE, comparing the short term outcomes with a historical control group. Methods: Non-randomized clinical trial. Infants born at 36 weeks gestation with perinatal asphyxia were included in the study. An hypothermia protocol was applied in all neonates diagnosed with HIE admitted to the NICU. Results: Six newborns underwent therapeutic hypothermia and their clinical outcomes were compared with 18 newborns admitted previously (control group). Mortality was lower in hypothermia group as well as the presence of disabilities in hospital discharge. Conclusion: Therapeutic hypothermia for treatment of HIE in newborn infants seems to be a safe and effective procedure having a significant impact in reducing the mortality rate and improving the neurodevelopmental in short term. 
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spelling Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource settingHipotermia para encefalopatia isquêmica hipóxica neonatal usando temperatura axilar: um tratamento eficaz em um ambiente com poucos recursosHypoxia-IschemiaBrainHypothermiaInducedNewbornHipóxia-Isquemia CerebralHipotermia induzidaRecém-nascidoTherapeutic hypothermia is the standard clinical practice for neonates with moderate to severe hypoxic ischaemic encephalopathy (HIE). Aim: To implement a therapeutic hypothermia protocol using axillary temperature in newborns with HIE, comparing the short term outcomes with a historical control group. Methods: Non-randomized clinical trial. Infants born at 36 weeks gestation with perinatal asphyxia were included in the study. An hypothermia protocol was applied in all neonates diagnosed with HIE admitted to the NICU. Results: Six newborns underwent therapeutic hypothermia and their clinical outcomes were compared with 18 newborns admitted previously (control group). Mortality was lower in hypothermia group as well as the presence of disabilities in hospital discharge. Conclusion: Therapeutic hypothermia for treatment of HIE in newborn infants seems to be a safe and effective procedure having a significant impact in reducing the mortality rate and improving the neurodevelopmental in short term. A hipotermia terapêutica é a prática clínica padrão para neonatos com encefalopatia isquêmica hipóxica moderada a grave (HIE). Objetivo: Implementar um protocolo de hipotermia terapêutica usando temperatura axilar em recém-nascidos com HIE, comparando os resultados a curto prazo com um grupo de controle histórico. Métodos: Ensaio clínico não randomizado. Os bebês nascidos com 36 semanas de gestação com asfixia perinatal foram incluídos no estudo. Um protocolo de hipotermia foi aplicado em todos os neonatos diagnosticados com HIE internados na UTIN. Resultados: Seis recém-nascidos foram submetidos a hipotermia terapêutica e seus resultados clínicos foram comparados com 18 recém-nascidos internados anteriormente (grupo controle). A mortalidade foi menor no grupo hipotermia e presença de incapacidades na alta hospitalar. Conclusão: A hipotermia terapêutica para o tratamento da HIE em recém-nascidos parece ser um procedimento seguro e eficaz, com impacto significativo na redução da taxa de mortalidade e na melhoria do neurodesenvolvimento a curto prazo.Universidade Federal de Santa Maria2018-04-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.ufsm.br/revistasaude/article/view/2128410.5902/2236583421284Saúde (Santa Maria); Revista Saúde (Santa Maria), Vol.44, n.1, Jan./Abril 2018Saúde (Santa Maria); Revista Saúde (Santa Maria), Vol.44, n.1, Jan./Abril 20182236-58340103-4499reponame:Saúde (Santa Maria)instname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMenghttps://periodicos.ufsm.br/revistasaude/article/view/21284/pdfCopyright (c) 2018 Saúde (Santa Maria)info:eu-repo/semantics/openAccessBinkowski, Raquel Trautenmüller KerberSilveira, Ana Ligia da SilvaSityá, Camila SantosHaeffner, Léris Salete BonfantiWeinmann, Angela Regina Maciel2020-01-30T19:57:25Zoai:ojs.pkp.sfu.ca:article/21284Revistahttps://periodicos.ufsm.br/revistasaudePUBhttps://periodicos.ufsm.br/revistasaude/oairevistasaude.ufsm@gmail.com || amanda.revsaude@gmail.com || beatriz.revsaude@gmail.com2236-58342236-5834opendoar:2020-01-30T19:57:25Saúde (Santa Maria) - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting
Hipotermia para encefalopatia isquêmica hipóxica neonatal usando temperatura axilar: um tratamento eficaz em um ambiente com poucos recursos
title Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting
spellingShingle Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting
Binkowski, Raquel Trautenmüller Kerber
Hypoxia-Ischemia
Brain
Hypothermia
Induced
Newborn
Hipóxia-Isquemia Cerebral
Hipotermia induzida
Recém-nascido
title_short Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting
title_full Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting
title_fullStr Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting
title_full_unstemmed Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting
title_sort Hypothermia for neonatal hypoxic ischemic encephalopathy using axillary temperature: an effective treatment in a low resource setting
author Binkowski, Raquel Trautenmüller Kerber
author_facet Binkowski, Raquel Trautenmüller Kerber
Silveira, Ana Ligia da Silva
Sityá, Camila Santos
Haeffner, Léris Salete Bonfanti
Weinmann, Angela Regina Maciel
author_role author
author2 Silveira, Ana Ligia da Silva
Sityá, Camila Santos
Haeffner, Léris Salete Bonfanti
Weinmann, Angela Regina Maciel
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Binkowski, Raquel Trautenmüller Kerber
Silveira, Ana Ligia da Silva
Sityá, Camila Santos
Haeffner, Léris Salete Bonfanti
Weinmann, Angela Regina Maciel
dc.subject.por.fl_str_mv Hypoxia-Ischemia
Brain
Hypothermia
Induced
Newborn
Hipóxia-Isquemia Cerebral
Hipotermia induzida
Recém-nascido
topic Hypoxia-Ischemia
Brain
Hypothermia
Induced
Newborn
Hipóxia-Isquemia Cerebral
Hipotermia induzida
Recém-nascido
description Therapeutic hypothermia is the standard clinical practice for neonates with moderate to severe hypoxic ischaemic encephalopathy (HIE). Aim: To implement a therapeutic hypothermia protocol using axillary temperature in newborns with HIE, comparing the short term outcomes with a historical control group. Methods: Non-randomized clinical trial. Infants born at 36 weeks gestation with perinatal asphyxia were included in the study. An hypothermia protocol was applied in all neonates diagnosed with HIE admitted to the NICU. Results: Six newborns underwent therapeutic hypothermia and their clinical outcomes were compared with 18 newborns admitted previously (control group). Mortality was lower in hypothermia group as well as the presence of disabilities in hospital discharge. Conclusion: Therapeutic hypothermia for treatment of HIE in newborn infants seems to be a safe and effective procedure having a significant impact in reducing the mortality rate and improving the neurodevelopmental in short term. 
publishDate 2018
dc.date.none.fl_str_mv 2018-04-18
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.ufsm.br/revistasaude/article/view/21284
10.5902/2236583421284
url https://periodicos.ufsm.br/revistasaude/article/view/21284
identifier_str_mv 10.5902/2236583421284
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.ufsm.br/revistasaude/article/view/21284/pdf
dc.rights.driver.fl_str_mv Copyright (c) 2018 Saúde (Santa Maria)
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Saúde (Santa Maria)
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv Saúde (Santa Maria); Revista Saúde (Santa Maria), Vol.44, n.1, Jan./Abril 2018
Saúde (Santa Maria); Revista Saúde (Santa Maria), Vol.44, n.1, Jan./Abril 2018
2236-5834
0103-4499
reponame:Saúde (Santa Maria)
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Saúde (Santa Maria)
collection Saúde (Santa Maria)
repository.name.fl_str_mv Saúde (Santa Maria) - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv revistasaude.ufsm@gmail.com || amanda.revsaude@gmail.com || beatriz.revsaude@gmail.com
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