Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário

Detalhes bibliográficos
Autor(a) principal: Gobbi, Débora Stefanello Golart
Data de Publicação: 2020
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações do UFSM
Texto Completo: http://repositorio.ufsm.br/handle/1/23572
Resumo: Objective: To assess the contribution of SNAP II, SNAP-PE II, CRIB and CRIB II severity scores as predictors of neonatal mortality in newborns admitted to an NICU in a given period. Methods: Prospective cohort study that involved newborns admitted in the NICU of Santa Maria University Hospital between August, 2018 and Jully, 2019. The exclusion criteria were: occurrence of death before 12 hours of life, presence of malformations or genetic syndromes incompatible with life (Trisomy of chromosome XIII and XVIII, hydranencephaly and corpus callosum agenesis) and newborns admitted from other hospitals. Results: 160 newborns were included with a median birth weight of 1835 grams and a gestational age of 34 weeks and 1 day, being 81.88% preterm infants. The mortality rate was 10%, being significantly higher in babies with birth weight below 1000 grams (p<0.0001). The four score applied were significantly higher in newborns who died in comparison with the survivors. SNAP II sensitivity was 81.2% and specificity 38.9%, with a positive predictive value was 95.7% and negative 17.9%. SNAPPE-II sensitivity was 87.5%, specificity 53.5%, positive predictive value 96.8% and negative 20%; for CRIB, the sensitivity and specificity were 66.7%, the positive predictive value was 82.7% and the negative 30%; and for CRIB II, the sensitivity was 83.3%, specificity 47.6%, positive predictive value 77.8% and negative 53.3%. The area under ROC curve was 0.70 for SNAP II and 0.84 for SNAP-PE II to the total number of newborns assessed (p=0.023). For those with birth weight <1500g, the areas were for CRIB 0.72, CRIB II 0.80, SNAP II 0.64 and SNAP-PE II 0.76 (p=0.046). Conclusion: Considering all the babies studied SNAP-PE II was the best predictor of mortality. For babies with birth weight <1500 grams CRIB II showed the best prediction performance.
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spelling 2022-01-18T18:06:22Z2022-01-18T18:06:22Z2020-04-20http://repositorio.ufsm.br/handle/1/23572Objective: To assess the contribution of SNAP II, SNAP-PE II, CRIB and CRIB II severity scores as predictors of neonatal mortality in newborns admitted to an NICU in a given period. Methods: Prospective cohort study that involved newborns admitted in the NICU of Santa Maria University Hospital between August, 2018 and Jully, 2019. The exclusion criteria were: occurrence of death before 12 hours of life, presence of malformations or genetic syndromes incompatible with life (Trisomy of chromosome XIII and XVIII, hydranencephaly and corpus callosum agenesis) and newborns admitted from other hospitals. Results: 160 newborns were included with a median birth weight of 1835 grams and a gestational age of 34 weeks and 1 day, being 81.88% preterm infants. The mortality rate was 10%, being significantly higher in babies with birth weight below 1000 grams (p<0.0001). The four score applied were significantly higher in newborns who died in comparison with the survivors. SNAP II sensitivity was 81.2% and specificity 38.9%, with a positive predictive value was 95.7% and negative 17.9%. SNAPPE-II sensitivity was 87.5%, specificity 53.5%, positive predictive value 96.8% and negative 20%; for CRIB, the sensitivity and specificity were 66.7%, the positive predictive value was 82.7% and the negative 30%; and for CRIB II, the sensitivity was 83.3%, specificity 47.6%, positive predictive value 77.8% and negative 53.3%. The area under ROC curve was 0.70 for SNAP II and 0.84 for SNAP-PE II to the total number of newborns assessed (p=0.023). For those with birth weight <1500g, the areas were for CRIB 0.72, CRIB II 0.80, SNAP II 0.64 and SNAP-PE II 0.76 (p=0.046). Conclusion: Considering all the babies studied SNAP-PE II was the best predictor of mortality. For babies with birth weight <1500 grams CRIB II showed the best prediction performance.Objetivo: Avaliar a contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal nos recém-nascidos internados numa UTIN em um determinado período. Métodos: Estudo prospectivo, de coorte, que envolveu os recém-nascidos internados na UTIN do Hospital Universitário de Santa Maria, no período compreendido entre agosto de 2018 a julho de 2019. Os critérios de exclusão foram: ocorrência de óbito antes de 12 horas de vida, a presença de malformações ou síndromes genéticas incompatíveis com a vida (Trissomia do cromossomo XIII e do XVIII, hidranencefalia e agenesia de corpo caloso) e os recém-nascidos admitidos de outros hospitais. Os escores avaliados foram o SNAP II, SNAP-PE II, CRIB e CRIB II, os dois últimos apenas para os RN com peso ao nascer < 1500g. Resultados: Foram incluídos 160 recém-nascidos, com mediana de peso ao nascer de 1835 gramas, e idade gestacional de 34 semanas e um dia, sendo 81,88% pré-termo. A mortalidade foi de 10%, sendo significativamente maior nos grupos de crianças com peso ao nascer inferior a 1000 gramas (p<0,0001). A pontuação, para os quatro escores aplicados, foi significativamente maior nos recém-nascidos que morreram, na comparação com os que sobreviveram. A sensibilidade do SNAP II foi de 81,2% e a especificidade de 38,9%, com um valor preditivo positivo foi 95,7% e negativo de 17,9%. Para o SNAPPE-II, a sensibilidade foi de 87,5%, a especificidade de 53,5%, o valor preditivo positivo de 96,8% e o negativo de 20%; o CRIB mostrou uma sensibilidade e especificidade de 66,7%, um valor preditivo positivo de 82,7% e negativo de 30%; e para o CRIB II, a sensibilidade foi de 83,3%, especificidade de 47,6%, valor preditivo positivo de 77,8% e negativo de 53,3%. A área sob a curva ROC para o SNAP II foi de 0,70 e para o SNAP-PE II de 0,84, no total dos RN avaliados (p=0,023). Para os com peso ao nascer <1500g, as áreas foram para o CRIB 0,72, CRIB II 0,80, SNAP II 0,64 e SNAP-PE II 0,76 (p=0,046). Conclusão: Considerando todos os RN estudados, o SNAP-PE II foi o melhor preditor de mortalidade, e, para os RN <1500 gramas, o CRIB II foi o que mostrou a melhor performance de predição.porUniversidade Federal de Santa MariaCentro de Ciências da SaúdePrograma de Pós-Graduação em Ciências da SaúdeUFSMBrasilCiências da SaúdeAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessMortalidade neonatalAvaliação de risco para saúdeEscoresNeonatal mortalityRisk assessmentScoresCNPQ::CIENCIAS DA SAUDEContribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitárioContribution of SNAP II, SNAP-PE II, CRIB and CRIB II gravity scores as predictors of neonatal mortality in a university hospitalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisWeinmann, Angela Regina Macielhttp://lattes.cnpq.br/9151119377173425Oliveira, Marinez Josefina Casarotto deHaeffner, Leris Salete Bonfantihttp://lattes.cnpq.br/3975064862502412Gobbi, Débora Stefanello Golart4000000000016006006006006001c5aefd6-6508-4d33-80c5-ebfe9227f0ffddfcf1ee-838d-40c5-b4b6-582eb103ba32cf6dd1ee-1b6f-4170-bb5f-2e1ef2c4479271c0a8f3-dcc6-4873-bcb1-a93724122534reponame:Biblioteca Digital de Teses e Dissertações do UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMORIGINALDIS_PPGCS_2020_GOBBI_DÉBORA.pdfDIS_PPGCS_2020_GOBBI_DÉBORA.pdfDissertação de Mestradoapplication/pdf1093397http://repositorio.ufsm.br/bitstream/1/23572/1/DIS_PPGCS_2020_GOBBI_D%c3%89BORA.pdfe7dd739a6f18c70c790ab99725e0b063MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805http://repositorio.ufsm.br/bitstream/1/23572/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81956http://repositorio.ufsm.br/bitstream/1/23572/3/license.txt2f0571ecee68693bd5cd3f17c1e075dfMD531/235722022-01-18 15:06:22.456oai:repositorio.ufsm.br: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 Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2022-01-18T18:06:22Biblioteca Digital de Teses e Dissertações do UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.por.fl_str_mv Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário
dc.title.alternative.eng.fl_str_mv Contribution of SNAP II, SNAP-PE II, CRIB and CRIB II gravity scores as predictors of neonatal mortality in a university hospital
title Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário
spellingShingle Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário
Gobbi, Débora Stefanello Golart
Mortalidade neonatal
Avaliação de risco para saúde
Escores
Neonatal mortality
Risk assessment
Scores
CNPQ::CIENCIAS DA SAUDE
title_short Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário
title_full Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário
title_fullStr Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário
title_full_unstemmed Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário
title_sort Contribuição dos escores de gravidade SNAP II, SNAP-PE II, CRIB e CRIB II como preditores de mortalidade neonatal em um hospital universitário
author Gobbi, Débora Stefanello Golart
author_facet Gobbi, Débora Stefanello Golart
author_role author
dc.contributor.advisor1.fl_str_mv Weinmann, Angela Regina Maciel
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9151119377173425
dc.contributor.referee1.fl_str_mv Oliveira, Marinez Josefina Casarotto de
dc.contributor.referee2.fl_str_mv Haeffner, Leris Salete Bonfanti
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/3975064862502412
dc.contributor.author.fl_str_mv Gobbi, Débora Stefanello Golart
contributor_str_mv Weinmann, Angela Regina Maciel
Oliveira, Marinez Josefina Casarotto de
Haeffner, Leris Salete Bonfanti
dc.subject.por.fl_str_mv Mortalidade neonatal
Avaliação de risco para saúde
Escores
topic Mortalidade neonatal
Avaliação de risco para saúde
Escores
Neonatal mortality
Risk assessment
Scores
CNPQ::CIENCIAS DA SAUDE
dc.subject.eng.fl_str_mv Neonatal mortality
Risk assessment
Scores
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS DA SAUDE
description Objective: To assess the contribution of SNAP II, SNAP-PE II, CRIB and CRIB II severity scores as predictors of neonatal mortality in newborns admitted to an NICU in a given period. Methods: Prospective cohort study that involved newborns admitted in the NICU of Santa Maria University Hospital between August, 2018 and Jully, 2019. The exclusion criteria were: occurrence of death before 12 hours of life, presence of malformations or genetic syndromes incompatible with life (Trisomy of chromosome XIII and XVIII, hydranencephaly and corpus callosum agenesis) and newborns admitted from other hospitals. Results: 160 newborns were included with a median birth weight of 1835 grams and a gestational age of 34 weeks and 1 day, being 81.88% preterm infants. The mortality rate was 10%, being significantly higher in babies with birth weight below 1000 grams (p<0.0001). The four score applied were significantly higher in newborns who died in comparison with the survivors. SNAP II sensitivity was 81.2% and specificity 38.9%, with a positive predictive value was 95.7% and negative 17.9%. SNAPPE-II sensitivity was 87.5%, specificity 53.5%, positive predictive value 96.8% and negative 20%; for CRIB, the sensitivity and specificity were 66.7%, the positive predictive value was 82.7% and the negative 30%; and for CRIB II, the sensitivity was 83.3%, specificity 47.6%, positive predictive value 77.8% and negative 53.3%. The area under ROC curve was 0.70 for SNAP II and 0.84 for SNAP-PE II to the total number of newborns assessed (p=0.023). For those with birth weight <1500g, the areas were for CRIB 0.72, CRIB II 0.80, SNAP II 0.64 and SNAP-PE II 0.76 (p=0.046). Conclusion: Considering all the babies studied SNAP-PE II was the best predictor of mortality. For babies with birth weight <1500 grams CRIB II showed the best prediction performance.
publishDate 2020
dc.date.issued.fl_str_mv 2020-04-20
dc.date.accessioned.fl_str_mv 2022-01-18T18:06:22Z
dc.date.available.fl_str_mv 2022-01-18T18:06:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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url http://repositorio.ufsm.br/handle/1/23572
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rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
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dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências da Saúde
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Ciências da Saúde
dc.publisher.initials.fl_str_mv UFSM
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Ciências da Saúde
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências da Saúde
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