Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/34815 http://dx.doi.org/10.1016/j.yebeh.2012.03.008 |
Resumo: | We examined the relationship between presence and frequency of different types of auras and side of lesion and post surgical outcomes in 205 patients with medically intractable mesial temporal lobe epilepsy (MTLE) with unilateral hippocampal sclerosis (HS). With respect to the number of auras, multiple auras were not associated with side of lesion (p=0.551). the side of HS was not associated with the type of auras reported. One hundred fifty-seven patients were operated. the occurrence of multiple auras was not associated with post-surgical outcome (p=0.740). the presence of extratemporal auras was significantly higher in patients with poor outcome. in conclusion, this study suggests that the presence of extratemporal auras in patients with MTLE-HS possibly reflects extratemporal epileptogenicity in these patients, who otherwise showed features suggestive of TLE. Therefore, TLE-HS patients undergoing pre-surgical evaluation and presenting clinical symptoms suggestive of extratemporal involvement should bemore extensively evaluated to avoid incomplete resection of the epileptogenic zone. (C) 2012 Elsevier Inc. All rights reserved. |
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Ferrari-Marinho, Taissa [UNIFESP]Caboclo, Luís Otávio Sales Ferreira [UNIFESP]Marinho, Murilo Martinez [UNIFESP]Centeno, Ricardo Silva [UNIFESP]Neves, Rafael Scarpa da Costa [UNIFESP]Santana, Maria Teresa Castilho Garcia de [UNIFESP]Britto, Fernanda dos Santos [UNIFESP]Carrete Junior, Henrique [UNIFESP]Yacubian, Elza Márcia Targas [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2016-01-24T14:27:08Z2016-01-24T14:27:08Z2012-05-01Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 24, n. 1, p. 120-125, 2012.1525-5050http://repositorio.unifesp.br/handle/11600/34815http://dx.doi.org/10.1016/j.yebeh.2012.03.008WOS000303814100021.pdf10.1016/j.yebeh.2012.03.008WOS:000303814100021We examined the relationship between presence and frequency of different types of auras and side of lesion and post surgical outcomes in 205 patients with medically intractable mesial temporal lobe epilepsy (MTLE) with unilateral hippocampal sclerosis (HS). With respect to the number of auras, multiple auras were not associated with side of lesion (p=0.551). the side of HS was not associated with the type of auras reported. One hundred fifty-seven patients were operated. the occurrence of multiple auras was not associated with post-surgical outcome (p=0.740). the presence of extratemporal auras was significantly higher in patients with poor outcome. in conclusion, this study suggests that the presence of extratemporal auras in patients with MTLE-HS possibly reflects extratemporal epileptogenicity in these patients, who otherwise showed features suggestive of TLE. Therefore, TLE-HS patients undergoing pre-surgical evaluation and presenting clinical symptoms suggestive of extratemporal involvement should bemore extensively evaluated to avoid incomplete resection of the epileptogenic zone. (C) 2012 Elsevier Inc. All rights reserved.Universidade Federal de São Paulo, Dept Neurol & Neurocirurgia, BR-04024002 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Diagnost Imagem, BR-04024002 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Neurol & Neurocirurgia, BR-04024002 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Diagnost Imagem, BR-04024002 São Paulo, BrazilWeb of Science120-125engElsevier B.V.Epilepsy & Behaviorhttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyinfo:eu-repo/semantics/openAccessTemporal lobe epilepsyHippocampal sclerosisAurasExtratemporal aurasPost surgical outcomeAuras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcomeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlereponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000303814100021.pdfapplication/pdf235220${dspace.ui.url}/bitstream/11600/34815/1/WOS000303814100021.pdffa729c932c31b3692684d46b6a127416MD51open accessTEXTWOS000303814100021.pdf.txtWOS000303814100021.pdf.txtExtracted texttext/plain37550${dspace.ui.url}/bitstream/11600/34815/2/WOS000303814100021.pdf.txt17dbe62d7572b0a1dc3fe2be93b38bdeMD52open access11600/348152023-01-12 21:52:29.228open accessoai:repositorio.unifesp.br:11600/34815Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:10:25.494229Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome |
title |
Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome |
spellingShingle |
Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome Ferrari-Marinho, Taissa [UNIFESP] Temporal lobe epilepsy Hippocampal sclerosis Auras Extratemporal auras Post surgical outcome |
title_short |
Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome |
title_full |
Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome |
title_fullStr |
Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome |
title_full_unstemmed |
Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome |
title_sort |
Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome |
author |
Ferrari-Marinho, Taissa [UNIFESP] |
author_facet |
Ferrari-Marinho, Taissa [UNIFESP] Caboclo, Luís Otávio Sales Ferreira [UNIFESP] Marinho, Murilo Martinez [UNIFESP] Centeno, Ricardo Silva [UNIFESP] Neves, Rafael Scarpa da Costa [UNIFESP] Santana, Maria Teresa Castilho Garcia de [UNIFESP] Britto, Fernanda dos Santos [UNIFESP] Carrete Junior, Henrique [UNIFESP] Yacubian, Elza Márcia Targas [UNIFESP] |
author_role |
author |
author2 |
Caboclo, Luís Otávio Sales Ferreira [UNIFESP] Marinho, Murilo Martinez [UNIFESP] Centeno, Ricardo Silva [UNIFESP] Neves, Rafael Scarpa da Costa [UNIFESP] Santana, Maria Teresa Castilho Garcia de [UNIFESP] Britto, Fernanda dos Santos [UNIFESP] Carrete Junior, Henrique [UNIFESP] Yacubian, Elza Márcia Targas [UNIFESP] |
author2_role |
author author author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Ferrari-Marinho, Taissa [UNIFESP] Caboclo, Luís Otávio Sales Ferreira [UNIFESP] Marinho, Murilo Martinez [UNIFESP] Centeno, Ricardo Silva [UNIFESP] Neves, Rafael Scarpa da Costa [UNIFESP] Santana, Maria Teresa Castilho Garcia de [UNIFESP] Britto, Fernanda dos Santos [UNIFESP] Carrete Junior, Henrique [UNIFESP] Yacubian, Elza Márcia Targas [UNIFESP] |
dc.subject.eng.fl_str_mv |
Temporal lobe epilepsy Hippocampal sclerosis Auras Extratemporal auras Post surgical outcome |
topic |
Temporal lobe epilepsy Hippocampal sclerosis Auras Extratemporal auras Post surgical outcome |
description |
We examined the relationship between presence and frequency of different types of auras and side of lesion and post surgical outcomes in 205 patients with medically intractable mesial temporal lobe epilepsy (MTLE) with unilateral hippocampal sclerosis (HS). With respect to the number of auras, multiple auras were not associated with side of lesion (p=0.551). the side of HS was not associated with the type of auras reported. One hundred fifty-seven patients were operated. the occurrence of multiple auras was not associated with post-surgical outcome (p=0.740). the presence of extratemporal auras was significantly higher in patients with poor outcome. in conclusion, this study suggests that the presence of extratemporal auras in patients with MTLE-HS possibly reflects extratemporal epileptogenicity in these patients, who otherwise showed features suggestive of TLE. Therefore, TLE-HS patients undergoing pre-surgical evaluation and presenting clinical symptoms suggestive of extratemporal involvement should bemore extensively evaluated to avoid incomplete resection of the epileptogenic zone. (C) 2012 Elsevier Inc. All rights reserved. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012-05-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T14:27:08Z |
dc.date.available.fl_str_mv |
2016-01-24T14:27:08Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 24, n. 1, p. 120-125, 2012. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/34815 http://dx.doi.org/10.1016/j.yebeh.2012.03.008 |
dc.identifier.issn.none.fl_str_mv |
1525-5050 |
dc.identifier.file.none.fl_str_mv |
WOS000303814100021.pdf |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.yebeh.2012.03.008 |
dc.identifier.wos.none.fl_str_mv |
WOS:000303814100021 |
identifier_str_mv |
Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 24, n. 1, p. 120-125, 2012. 1525-5050 WOS000303814100021.pdf 10.1016/j.yebeh.2012.03.008 WOS:000303814100021 |
url |
http://repositorio.unifesp.br/handle/11600/34815 http://dx.doi.org/10.1016/j.yebeh.2012.03.008 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Epilepsy & Behavior |
dc.rights.driver.fl_str_mv |
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
120-125 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
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