In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi

Detalhes bibliográficos
Autor(a) principal: Goncalves, Sarah S. [UNIFESP]
Data de Publicação: 2013
Outros Autores: Stchigel, Alberto M., Cano, Josep, Guarro, Josep, Colombo, Arnaldo L. [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://repositorio.unifesp.br/handle/11600/36121
http://dx.doi.org/10.1128/AAC.01902-12
Resumo: The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant species of Aspergillus section Flavi, including those of different phylogenetic clades of A. flavus, was tested for nine antifungal agents using a microdilution reference method (CLSI, M38-A2). Terbinafine and the echinocandins demonstrated lower MICs/MECs for all species evaluated, followed by posaconazole. Amphotericin B showed MICs >= 2 mu g/ml for 38 (49.4%) of the 77 isolates tested.
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spelling Goncalves, Sarah S. [UNIFESP]Stchigel, Alberto M.Cano, JosepGuarro, JosepColombo, Arnaldo L. [UNIFESP]Universidade Federal de São Paulo (UNIFESP)Univ Rovira & Virgili2016-01-24T14:31:28Z2016-01-24T14:31:28Z2013-04-01Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 57, n. 4, p. 1944-1947, 2013.0066-4804http://repositorio.unifesp.br/handle/11600/36121http://dx.doi.org/10.1128/AAC.01902-12WOS000316119100056.pdf10.1128/AAC.01902-12WOS:000316119100056The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant species of Aspergillus section Flavi, including those of different phylogenetic clades of A. flavus, was tested for nine antifungal agents using a microdilution reference method (CLSI, M38-A2). Terbinafine and the echinocandins demonstrated lower MICs/MECs for all species evaluated, followed by posaconazole. Amphotericin B showed MICs >= 2 mu g/ml for 38 (49.4%) of the 77 isolates tested.Spanish Ministerio de Educacion y CienciaCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Federal de São Paulo, Dept Med, Special Mycol Lab LEMI, São Paulo, BrazilUniv Rovira & Virgili, Sch Med, IISPV, Mycol Unit, E-43201 Reus, SpainUniversidade Federal de São Paulo, Dept Med, Special Mycol Lab LEMI, São Paulo, BrazilSpanish Ministerio de Educacion y Ciencia: CGL 2009-08698/BOSCAPES: SWE 4150-08-2CAPES: 2312/2011CNPq: GM/GD 142051/2007-1FAPESP: 2012/01134-8Web of Science1944-1947engAmer Soc MicrobiologyAntimicrobial Agents and ChemotherapyIn Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flaviinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000316119100056.pdfapplication/pdf110109${dspace.ui.url}/bitstream/11600/36121/1/WOS000316119100056.pdfd65e24b3a12ed77a8bf97566ae4129f7MD51open accessTEXTWOS000316119100056.pdf.txtWOS000316119100056.pdf.txtExtracted texttext/plain17732${dspace.ui.url}/bitstream/11600/36121/2/WOS000316119100056.pdf.txtb31c2465a754f9fd1716f66aca7b6efbMD52open access11600/361212022-09-27 12:00:39.164open accessoai:repositorio.unifesp.br:11600/36121Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:26:32.175282Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.en.fl_str_mv In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi
title In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi
spellingShingle In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi
Goncalves, Sarah S. [UNIFESP]
title_short In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi
title_full In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi
title_fullStr In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi
title_full_unstemmed In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi
title_sort In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi
author Goncalves, Sarah S. [UNIFESP]
author_facet Goncalves, Sarah S. [UNIFESP]
Stchigel, Alberto M.
Cano, Josep
Guarro, Josep
Colombo, Arnaldo L. [UNIFESP]
author_role author
author2 Stchigel, Alberto M.
Cano, Josep
Guarro, Josep
Colombo, Arnaldo L. [UNIFESP]
author2_role author
author
author
author
dc.contributor.institution.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Univ Rovira & Virgili
dc.contributor.author.fl_str_mv Goncalves, Sarah S. [UNIFESP]
Stchigel, Alberto M.
Cano, Josep
Guarro, Josep
Colombo, Arnaldo L. [UNIFESP]
description The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant species of Aspergillus section Flavi, including those of different phylogenetic clades of A. flavus, was tested for nine antifungal agents using a microdilution reference method (CLSI, M38-A2). Terbinafine and the echinocandins demonstrated lower MICs/MECs for all species evaluated, followed by posaconazole. Amphotericin B showed MICs >= 2 mu g/ml for 38 (49.4%) of the 77 isolates tested.
publishDate 2013
dc.date.issued.fl_str_mv 2013-04-01
dc.date.accessioned.fl_str_mv 2016-01-24T14:31:28Z
dc.date.available.fl_str_mv 2016-01-24T14:31:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 57, n. 4, p. 1944-1947, 2013.
dc.identifier.uri.fl_str_mv http://repositorio.unifesp.br/handle/11600/36121
http://dx.doi.org/10.1128/AAC.01902-12
dc.identifier.issn.none.fl_str_mv 0066-4804
dc.identifier.file.none.fl_str_mv WOS000316119100056.pdf
dc.identifier.doi.none.fl_str_mv 10.1128/AAC.01902-12
dc.identifier.wos.none.fl_str_mv WOS:000316119100056
identifier_str_mv Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 57, n. 4, p. 1944-1947, 2013.
0066-4804
WOS000316119100056.pdf
10.1128/AAC.01902-12
WOS:000316119100056
url http://repositorio.unifesp.br/handle/11600/36121
http://dx.doi.org/10.1128/AAC.01902-12
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Antimicrobial Agents and Chemotherapy
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1944-1947
dc.publisher.none.fl_str_mv Amer Soc Microbiology
publisher.none.fl_str_mv Amer Soc Microbiology
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
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