The effects of low level laser therapy on injured skeletal muscle
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/8232 http://dx.doi.org/10.1590/S1516-89132014000100008 |
Resumo: | The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm² when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion. |
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Renno, Ana Claudia Muniz [UNIFESP]Assis, Lívia [UNIFESP]Peres, Beatriz [UNIFESP]Rodrigues, Natalia CamargoBrunelli, Roberta de MatosToma, Renata Luri [UNIFESP]Medalha, Carla Christina [UNIFESP]Ribeiro, Daniel Araki [UNIFESP]Universidade Federal de São Paulo (UNIFESP)Universidade Federal de São Carlos Centro de Ciências Biológicas e da Saúde Departamento de Fisioterapia2015-06-14T13:46:56Z2015-06-14T13:46:56Z2014-02-01Brazilian Archives of Biology and Technology. Instituto de Tecnologia do Paraná - Tecpar, v. 57, n. 1, p. 48-54, 2014.1516-8913http://repositorio.unifesp.br/handle/11600/8232http://dx.doi.org/10.1590/S1516-89132014000100008S1516-89132014000100008.pdfS1516-8913201400010000810.1590/S1516-89132014000100008WOS:000332125000008The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm² when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Federal de São Paulo (UNIFESP) Departamento de BiociênciasUniversidade Federal de São Carlos Centro de Ciências Biológicas e da Saúde Departamento de FisioterapiaUNIFESP, Depto. de BiociênciasSciELO48-54engInstituto de Tecnologia do Paraná - TecparBrazilian Archives of Biology and Technologylow level laser therapyratmuscle repairCOX-2The effects of low level laser therapy on injured skeletal muscleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1516-89132014000100008.pdfapplication/pdf176669${dspace.ui.url}/bitstream/11600/8232/1/S1516-89132014000100008.pdfefa5459973b3c8142f8017f407a278e9MD51open accessTEXTS1516-89132014000100008.pdf.txtS1516-89132014000100008.pdf.txtExtracted texttext/plain26588${dspace.ui.url}/bitstream/11600/8232/6/S1516-89132014000100008.pdf.txtb54446deb7f16d485ce40257eb7df773MD56open accessTHUMBNAILS1516-89132014000100008.pdf.jpgS1516-89132014000100008.pdf.jpgIM Thumbnailimage/jpeg5832${dspace.ui.url}/bitstream/11600/8232/8/S1516-89132014000100008.pdf.jpg51f66f04e3fea014a2f64744064c7307MD58open access11600/82322023-06-05 19:09:18.981open accessoai:repositorio.unifesp.br:11600/8232Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-06-05T22:09:18Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
The effects of low level laser therapy on injured skeletal muscle |
title |
The effects of low level laser therapy on injured skeletal muscle |
spellingShingle |
The effects of low level laser therapy on injured skeletal muscle Renno, Ana Claudia Muniz [UNIFESP] low level laser therapy rat muscle repair COX-2 |
title_short |
The effects of low level laser therapy on injured skeletal muscle |
title_full |
The effects of low level laser therapy on injured skeletal muscle |
title_fullStr |
The effects of low level laser therapy on injured skeletal muscle |
title_full_unstemmed |
The effects of low level laser therapy on injured skeletal muscle |
title_sort |
The effects of low level laser therapy on injured skeletal muscle |
author |
Renno, Ana Claudia Muniz [UNIFESP] |
author_facet |
Renno, Ana Claudia Muniz [UNIFESP] Assis, Lívia [UNIFESP] Peres, Beatriz [UNIFESP] Rodrigues, Natalia Camargo Brunelli, Roberta de Matos Toma, Renata Luri [UNIFESP] Medalha, Carla Christina [UNIFESP] Ribeiro, Daniel Araki [UNIFESP] |
author_role |
author |
author2 |
Assis, Lívia [UNIFESP] Peres, Beatriz [UNIFESP] Rodrigues, Natalia Camargo Brunelli, Roberta de Matos Toma, Renata Luri [UNIFESP] Medalha, Carla Christina [UNIFESP] Ribeiro, Daniel Araki [UNIFESP] |
author2_role |
author author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Universidade Federal de São Carlos Centro de Ciências Biológicas e da Saúde Departamento de Fisioterapia |
dc.contributor.author.fl_str_mv |
Renno, Ana Claudia Muniz [UNIFESP] Assis, Lívia [UNIFESP] Peres, Beatriz [UNIFESP] Rodrigues, Natalia Camargo Brunelli, Roberta de Matos Toma, Renata Luri [UNIFESP] Medalha, Carla Christina [UNIFESP] Ribeiro, Daniel Araki [UNIFESP] |
dc.subject.eng.fl_str_mv |
low level laser therapy rat muscle repair COX-2 |
topic |
low level laser therapy rat muscle repair COX-2 |
description |
The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm² when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014-02-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:46:56Z |
dc.date.available.fl_str_mv |
2015-06-14T13:46:56Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Brazilian Archives of Biology and Technology. Instituto de Tecnologia do Paraná - Tecpar, v. 57, n. 1, p. 48-54, 2014. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/8232 http://dx.doi.org/10.1590/S1516-89132014000100008 |
dc.identifier.issn.none.fl_str_mv |
1516-8913 |
dc.identifier.file.none.fl_str_mv |
S1516-89132014000100008.pdf |
dc.identifier.scielo.none.fl_str_mv |
S1516-89132014000100008 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S1516-89132014000100008 |
dc.identifier.wos.none.fl_str_mv |
WOS:000332125000008 |
identifier_str_mv |
Brazilian Archives of Biology and Technology. Instituto de Tecnologia do Paraná - Tecpar, v. 57, n. 1, p. 48-54, 2014. 1516-8913 S1516-89132014000100008.pdf S1516-89132014000100008 10.1590/S1516-89132014000100008 WOS:000332125000008 |
url |
http://repositorio.unifesp.br/handle/11600/8232 http://dx.doi.org/10.1590/S1516-89132014000100008 |
dc.language.iso.fl_str_mv |
eng |
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eng |
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Brazilian Archives of Biology and Technology |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
48-54 |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
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