Sleep patterns over 15-day period in rats with spinal cord injury
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/29680 http://dx.doi.org/10.1038/sj.sc.3101971 |
Resumo: | Study design: Experimental, controlled trial.Objectives: the purpose of this study was to evaluate over a 15-day period alterations in sleep pattern of rats after spinal cord injury (SCI).Setting: Federal University of São Paulo, Department of Psychobiology.Methods: in total, 20 male Wistar rats were used. the rats were divided in two groups: SHAM and SCI. the rats were submitted to the following procedures: electrode insertion surgery, 24 h duration baseline sleep recording, SCI (level T9) and subsequent sleep recording for 15 consecutive days.Results: the results showed a reduction in sleep efficiency in the light period for Days 1-3, 5, 10 and 12 after SCI in relation to the SHAM group, with alterations in total waking time and sleep stages. Limb movements were observed 4 days after SCI.Conclusion: the present findings suggest that SCI may be heavily involved in altering sleep pattern in SCI subjects and that the inactivity caused by SCI may be exacerbating this altered sleep pattern. |
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Esteves, A. M.Mello, Marco Tulio de [UNIFESP]Squarcini, C. F. R.Lancellotti, Carmen Lucia PenteadoComparoni, Aniella [UNIFESP]Tufik, Sergio [UNIFESP]Universidade Federal de São Paulo (UNIFESP)Santa Casa2016-01-24T13:48:37Z2016-01-24T13:48:37Z2007-05-01Spinal Cord. London: Nature Publishing Group, v. 45, n. 5, p. 360-366, 2007.1362-4393http://repositorio.unifesp.br/handle/11600/29680http://dx.doi.org/10.1038/sj.sc.310197110.1038/sj.sc.3101971WOS:000246307900005Study design: Experimental, controlled trial.Objectives: the purpose of this study was to evaluate over a 15-day period alterations in sleep pattern of rats after spinal cord injury (SCI).Setting: Federal University of São Paulo, Department of Psychobiology.Methods: in total, 20 male Wistar rats were used. the rats were divided in two groups: SHAM and SCI. the rats were submitted to the following procedures: electrode insertion surgery, 24 h duration baseline sleep recording, SCI (level T9) and subsequent sleep recording for 15 consecutive days.Results: the results showed a reduction in sleep efficiency in the light period for Days 1-3, 5, 10 and 12 after SCI in relation to the SHAM group, with alterations in total waking time and sleep stages. Limb movements were observed 4 days after SCI.Conclusion: the present findings suggest that SCI may be heavily involved in altering sleep pattern in SCI subjects and that the inactivity caused by SCI may be exacerbating this altered sleep pattern.Universidade Federal de São Paulo, Dept Psychobiol, BR-04020060 São Paulo, BrazilUniversidade Federal de São Paulo, Ctr Psychobiol & Exercise Res, BR-04020060 São Paulo, BrazilSanta Casa, Dept Pathol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Psychobiol, BR-04020060 São Paulo, BrazilUniversidade Federal de São Paulo, Ctr Psychobiol & Exercise Res, BR-04020060 São Paulo, BrazilWeb of Science360-366engNature Publishing GroupSpinal Cordspinal cord injurysleep patternlimb movementratsSleep patterns over 15-day period in rats with spinal cord injuryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/296802022-06-02 09:35:07.292metadata only accessoai:repositorio.unifesp.br:11600/29680Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:16:27.289243Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Sleep patterns over 15-day period in rats with spinal cord injury |
title |
Sleep patterns over 15-day period in rats with spinal cord injury |
spellingShingle |
Sleep patterns over 15-day period in rats with spinal cord injury Esteves, A. M. spinal cord injury sleep pattern limb movement rats |
title_short |
Sleep patterns over 15-day period in rats with spinal cord injury |
title_full |
Sleep patterns over 15-day period in rats with spinal cord injury |
title_fullStr |
Sleep patterns over 15-day period in rats with spinal cord injury |
title_full_unstemmed |
Sleep patterns over 15-day period in rats with spinal cord injury |
title_sort |
Sleep patterns over 15-day period in rats with spinal cord injury |
author |
Esteves, A. M. |
author_facet |
Esteves, A. M. Mello, Marco Tulio de [UNIFESP] Squarcini, C. F. R. Lancellotti, Carmen Lucia Penteado Comparoni, Aniella [UNIFESP] Tufik, Sergio [UNIFESP] |
author_role |
author |
author2 |
Mello, Marco Tulio de [UNIFESP] Squarcini, C. F. R. Lancellotti, Carmen Lucia Penteado Comparoni, Aniella [UNIFESP] Tufik, Sergio [UNIFESP] |
author2_role |
author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Santa Casa |
dc.contributor.author.fl_str_mv |
Esteves, A. M. Mello, Marco Tulio de [UNIFESP] Squarcini, C. F. R. Lancellotti, Carmen Lucia Penteado Comparoni, Aniella [UNIFESP] Tufik, Sergio [UNIFESP] |
dc.subject.eng.fl_str_mv |
spinal cord injury sleep pattern limb movement rats |
topic |
spinal cord injury sleep pattern limb movement rats |
description |
Study design: Experimental, controlled trial.Objectives: the purpose of this study was to evaluate over a 15-day period alterations in sleep pattern of rats after spinal cord injury (SCI).Setting: Federal University of São Paulo, Department of Psychobiology.Methods: in total, 20 male Wistar rats were used. the rats were divided in two groups: SHAM and SCI. the rats were submitted to the following procedures: electrode insertion surgery, 24 h duration baseline sleep recording, SCI (level T9) and subsequent sleep recording for 15 consecutive days.Results: the results showed a reduction in sleep efficiency in the light period for Days 1-3, 5, 10 and 12 after SCI in relation to the SHAM group, with alterations in total waking time and sleep stages. Limb movements were observed 4 days after SCI.Conclusion: the present findings suggest that SCI may be heavily involved in altering sleep pattern in SCI subjects and that the inactivity caused by SCI may be exacerbating this altered sleep pattern. |
publishDate |
2007 |
dc.date.issued.fl_str_mv |
2007-05-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T13:48:37Z |
dc.date.available.fl_str_mv |
2016-01-24T13:48:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Spinal Cord. London: Nature Publishing Group, v. 45, n. 5, p. 360-366, 2007. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/29680 http://dx.doi.org/10.1038/sj.sc.3101971 |
dc.identifier.issn.none.fl_str_mv |
1362-4393 |
dc.identifier.doi.none.fl_str_mv |
10.1038/sj.sc.3101971 |
dc.identifier.wos.none.fl_str_mv |
WOS:000246307900005 |
identifier_str_mv |
Spinal Cord. London: Nature Publishing Group, v. 45, n. 5, p. 360-366, 2007. 1362-4393 10.1038/sj.sc.3101971 WOS:000246307900005 |
url |
http://repositorio.unifesp.br/handle/11600/29680 http://dx.doi.org/10.1038/sj.sc.3101971 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Spinal Cord |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
360-366 |
dc.publisher.none.fl_str_mv |
Nature Publishing Group |
publisher.none.fl_str_mv |
Nature Publishing Group |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
_version_ |
1783460235990532096 |