Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine
Autor(a) principal: | |
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Data de Publicação: | 1999 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/26144 http://dx.doi.org/10.1086/315018 |
Resumo: | A protective herd effect has been described after susceptible populations of children are vaccinated with conjugate Haemophilus influenzae type b (Hib), Hib carriage was studied in children aged 6-24 months attending day care centers in two cities in southern Brazil (Curitiba and Porto Alegre), in Curitiba, routine immunization with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine (PRP-T) in combination with diphtheria-tetanus toxoids-pertussis vaccine (PRP-T/DTP) has been offered since September 1996; DTP vaccine alone is routinely given in Porto Alegre, Children in Porto Alegre (n = 643) were 8 times less likely to have received adequate Hib vaccination and 4 times more likely to be Hib carriers than children in Curitiba (n = 647; i.e., point prevalence of oropharyngeal colonization, 4.8% vs. 1.2%). Point prevalence of carriage with non-type b or other nontypeable Hi was similar in children of both cities, There was a vaccination effect on carriage rates in children who received a primary 3-dose series, independent of the booster dose, suggesting that a booster may be unnecessary to induce population protection. |
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Forleo-Neto, E.Oliveira, C. F. de [UNIFESP]Maluf, EMCPBataglin, C.Araujo, JMRKunz, L. F.Pustai, A. K.Vieria, VSDZanella, R. C.Brandileone, M. C.Mimica, LMJMimica, I. M.Pasteur Merieux Connaught BrasilUniversidade Federal de São Paulo (UNIFESP)Secretaria Estado Saude São PauloSanta Casa Misericordia São PauloSecretaria Municipal Saude CuritibaSecretaria Municipal Saude Porto Alegre2016-01-24T12:30:53Z2016-01-24T12:30:53Z1999-10-01Journal of Infectious Diseases. Chicago: Univ Chicago Press, v. 180, n. 4, p. 1153-1158, 1999.0022-1899http://repositorio.unifesp.br/handle/11600/26144http://dx.doi.org/10.1086/315018WOS000083019500028.pdf10.1086/315018WOS:000083019500028A protective herd effect has been described after susceptible populations of children are vaccinated with conjugate Haemophilus influenzae type b (Hib), Hib carriage was studied in children aged 6-24 months attending day care centers in two cities in southern Brazil (Curitiba and Porto Alegre), in Curitiba, routine immunization with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine (PRP-T) in combination with diphtheria-tetanus toxoids-pertussis vaccine (PRP-T/DTP) has been offered since September 1996; DTP vaccine alone is routinely given in Porto Alegre, Children in Porto Alegre (n = 643) were 8 times less likely to have received adequate Hib vaccination and 4 times more likely to be Hib carriers than children in Curitiba (n = 647; i.e., point prevalence of oropharyngeal colonization, 4.8% vs. 1.2%). Point prevalence of carriage with non-type b or other nontypeable Hi was similar in children of both cities, There was a vaccination effect on carriage rates in children who received a primary 3-dose series, independent of the booster dose, suggesting that a booster may be unnecessary to induce population protection.Pasteur Merieux Connaught Brasil, Dept Med, BR-04552905 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Pediat, São Paulo, BrazilSecretaria Estado Saude São Paulo, Inst Adolfo Lutz, Seccao Bacteriol, São Paulo, BrazilSanta Casa Misericordia São Paulo, Fac Ciencias Med, Dept Patol, São Paulo, BrazilSecretaria Municipal Saude Curitiba, Dept Epidemiol, Curitiba, Parana, BrazilSecretaria Municipal Saude Porto Alegre, Dept Epidemiol, Porto Alegre, RS, BrazilUniversidade Federal de São Paulo, Dept Pediat, São Paulo, BrazilWeb of Science1153-1158engUniv Chicago PressJournal of Infectious DiseasesDecreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000083019500028.pdfapplication/pdf82854${dspace.ui.url}/bitstream/11600/26144/1/WOS000083019500028.pdffd8be1289b9317c31d0f3e847e35b394MD51open accessTEXTWOS000083019500028.pdf.txtWOS000083019500028.pdf.txtExtracted texttext/plain32081${dspace.ui.url}/bitstream/11600/26144/2/WOS000083019500028.pdf.txt4c389f8a6c961ce42edc8f05faec40edMD52open access11600/261442022-11-04 15:45:38.645open accessoai:repositorio.unifesp.br:11600/26144Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:29:55.146426Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine |
title |
Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine |
spellingShingle |
Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine Forleo-Neto, E. |
title_short |
Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine |
title_full |
Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine |
title_fullStr |
Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine |
title_full_unstemmed |
Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine |
title_sort |
Decreased point prevalence of Haemophilus influenzae type b (Hib) oropharyngeal colonization by mass immunization of Brazilian children less than 5 years old with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine in combination with diphtheria-tetanus toxoids-pertussis vaccine |
author |
Forleo-Neto, E. |
author_facet |
Forleo-Neto, E. Oliveira, C. F. de [UNIFESP] Maluf, EMCP Bataglin, C. Araujo, JMR Kunz, L. F. Pustai, A. K. Vieria, VSD Zanella, R. C. Brandileone, M. C. Mimica, LMJ Mimica, I. M. |
author_role |
author |
author2 |
Oliveira, C. F. de [UNIFESP] Maluf, EMCP Bataglin, C. Araujo, JMR Kunz, L. F. Pustai, A. K. Vieria, VSD Zanella, R. C. Brandileone, M. C. Mimica, LMJ Mimica, I. M. |
author2_role |
author author author author author author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Pasteur Merieux Connaught Brasil Universidade Federal de São Paulo (UNIFESP) Secretaria Estado Saude São Paulo Santa Casa Misericordia São Paulo Secretaria Municipal Saude Curitiba Secretaria Municipal Saude Porto Alegre |
dc.contributor.author.fl_str_mv |
Forleo-Neto, E. Oliveira, C. F. de [UNIFESP] Maluf, EMCP Bataglin, C. Araujo, JMR Kunz, L. F. Pustai, A. K. Vieria, VSD Zanella, R. C. Brandileone, M. C. Mimica, LMJ Mimica, I. M. |
description |
A protective herd effect has been described after susceptible populations of children are vaccinated with conjugate Haemophilus influenzae type b (Hib), Hib carriage was studied in children aged 6-24 months attending day care centers in two cities in southern Brazil (Curitiba and Porto Alegre), in Curitiba, routine immunization with Hib polyribosylribitol phosphate polysaccharide-tetanus toroid conjugate vaccine (PRP-T) in combination with diphtheria-tetanus toxoids-pertussis vaccine (PRP-T/DTP) has been offered since September 1996; DTP vaccine alone is routinely given in Porto Alegre, Children in Porto Alegre (n = 643) were 8 times less likely to have received adequate Hib vaccination and 4 times more likely to be Hib carriers than children in Curitiba (n = 647; i.e., point prevalence of oropharyngeal colonization, 4.8% vs. 1.2%). Point prevalence of carriage with non-type b or other nontypeable Hi was similar in children of both cities, There was a vaccination effect on carriage rates in children who received a primary 3-dose series, independent of the booster dose, suggesting that a booster may be unnecessary to induce population protection. |
publishDate |
1999 |
dc.date.issued.fl_str_mv |
1999-10-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T12:30:53Z |
dc.date.available.fl_str_mv |
2016-01-24T12:30:53Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Journal of Infectious Diseases. Chicago: Univ Chicago Press, v. 180, n. 4, p. 1153-1158, 1999. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/26144 http://dx.doi.org/10.1086/315018 |
dc.identifier.issn.none.fl_str_mv |
0022-1899 |
dc.identifier.file.none.fl_str_mv |
WOS000083019500028.pdf |
dc.identifier.doi.none.fl_str_mv |
10.1086/315018 |
dc.identifier.wos.none.fl_str_mv |
WOS:000083019500028 |
identifier_str_mv |
Journal of Infectious Diseases. Chicago: Univ Chicago Press, v. 180, n. 4, p. 1153-1158, 1999. 0022-1899 WOS000083019500028.pdf 10.1086/315018 WOS:000083019500028 |
url |
http://repositorio.unifesp.br/handle/11600/26144 http://dx.doi.org/10.1086/315018 |
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eng |
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eng |
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Journal of Infectious Diseases |
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1153-1158 |
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Univ Chicago Press |
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Univ Chicago Press |
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