Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/28798 http://dx.doi.org/10.1038/sj.eye.6701896 |
Resumo: | Aims To establish four normal retinal nerve fibre layer (RNFL) thickness radial profiles based on third-generation optical coherence tomography (OCT) and to compare them with previously reported histologic measurements.Methods A total of 20 normal eyes were studied. A circular scan was adjusted to the size of the optic disc and three scans were performed with this radius and every 200 mu m thereafter, up to a distance of 1400 mu m. Four different radial sections (superotemporal, superonasal, inferonasal, and inferotemporal) were studied to establish RNFL thickness OCT profiles. Additionally, two radial scans orientated at 45 and 1351 crossing the optic disc centre were performed in six of 20 eyes, and RNFL thickness was measured at disc margin.Results Quadrant location and distance from disc margin interaction in RNFL thickness was statistically significant (P < 0.001). the RNFL thickness decreased (P < 0.001) as the distance from the disc margin increased for all sections. the measurements automatically generated by the OCT built-in software were thinner (P < 0.001) than histologic ones close to the disc margin.Conclusions Four normal OCT RNFL profiles were established and compared with histological data obtained from the same area. RNFL measurements assessed by OCT 3 were significantly thinner close to the optic disc margin. |
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Skaf, M.[UNIFESP]Bernardes, A. B.Cardillo, J. A.Costa, R. A.Melo, Luiz Alberto Soares [UNIFESP]Castro, J. C.Varma, R.Hosp Olhos AraraquaraUniversidade Federal de São Paulo (UNIFESP)Universidade de São Paulo (USP)Univ So Calif2016-01-24T12:41:02Z2016-01-24T12:41:02Z2006-04-01Eye. London: Nature Publishing Group, v. 20, n. 4, p. 431-439, 2006.0950-222Xhttp://repositorio.unifesp.br/handle/11600/28798http://dx.doi.org/10.1038/sj.eye.670189610.1038/sj.eye.6701896WOS:000236561100006Aims To establish four normal retinal nerve fibre layer (RNFL) thickness radial profiles based on third-generation optical coherence tomography (OCT) and to compare them with previously reported histologic measurements.Methods A total of 20 normal eyes were studied. A circular scan was adjusted to the size of the optic disc and three scans were performed with this radius and every 200 mu m thereafter, up to a distance of 1400 mu m. Four different radial sections (superotemporal, superonasal, inferonasal, and inferotemporal) were studied to establish RNFL thickness OCT profiles. Additionally, two radial scans orientated at 45 and 1351 crossing the optic disc centre were performed in six of 20 eyes, and RNFL thickness was measured at disc margin.Results Quadrant location and distance from disc margin interaction in RNFL thickness was statistically significant (P < 0.001). the RNFL thickness decreased (P < 0.001) as the distance from the disc margin increased for all sections. the measurements automatically generated by the OCT built-in software were thinner (P < 0.001) than histologic ones close to the disc margin.Conclusions Four normal OCT RNFL profiles were established and compared with histological data obtained from the same area. RNFL measurements assessed by OCT 3 were significantly thinner close to the optic disc margin.Hosp Olhos Araraquara, Glaucoma Sect, BR-14802530 Araraquara, SP, BrazilHosp Olhos Araraquara, Retina Diagnost & Treatment Div, BR-14802530 Araraquara, SP, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilUSP, Inst Fis Sao Carlos, Sao Carlos, SP, BrazilUniv So Calif, Doheny Eye Inst, Dept Ophthalmol, Los Angeles, CA USAUniversidade Federal de São Paulo, EPM, São Paulo, BrazilWeb of Science431-439engNature Publishing GroupEyeRetinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomographyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/287982022-07-08 10:51:16.807metadata only accessoai:repositorio.unifesp.br:11600/28798Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:20:59.134379Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography |
title |
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography |
spellingShingle |
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography Skaf, M.[UNIFESP] |
title_short |
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography |
title_full |
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography |
title_fullStr |
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography |
title_full_unstemmed |
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography |
title_sort |
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography |
author |
Skaf, M.[UNIFESP] |
author_facet |
Skaf, M.[UNIFESP] Bernardes, A. B. Cardillo, J. A. Costa, R. A. Melo, Luiz Alberto Soares [UNIFESP] Castro, J. C. Varma, R. |
author_role |
author |
author2 |
Bernardes, A. B. Cardillo, J. A. Costa, R. A. Melo, Luiz Alberto Soares [UNIFESP] Castro, J. C. Varma, R. |
author2_role |
author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Hosp Olhos Araraquara Universidade Federal de São Paulo (UNIFESP) Universidade de São Paulo (USP) Univ So Calif |
dc.contributor.author.fl_str_mv |
Skaf, M.[UNIFESP] Bernardes, A. B. Cardillo, J. A. Costa, R. A. Melo, Luiz Alberto Soares [UNIFESP] Castro, J. C. Varma, R. |
description |
Aims To establish four normal retinal nerve fibre layer (RNFL) thickness radial profiles based on third-generation optical coherence tomography (OCT) and to compare them with previously reported histologic measurements.Methods A total of 20 normal eyes were studied. A circular scan was adjusted to the size of the optic disc and three scans were performed with this radius and every 200 mu m thereafter, up to a distance of 1400 mu m. Four different radial sections (superotemporal, superonasal, inferonasal, and inferotemporal) were studied to establish RNFL thickness OCT profiles. Additionally, two radial scans orientated at 45 and 1351 crossing the optic disc centre were performed in six of 20 eyes, and RNFL thickness was measured at disc margin.Results Quadrant location and distance from disc margin interaction in RNFL thickness was statistically significant (P < 0.001). the RNFL thickness decreased (P < 0.001) as the distance from the disc margin increased for all sections. the measurements automatically generated by the OCT built-in software were thinner (P < 0.001) than histologic ones close to the disc margin.Conclusions Four normal OCT RNFL profiles were established and compared with histological data obtained from the same area. RNFL measurements assessed by OCT 3 were significantly thinner close to the optic disc margin. |
publishDate |
2006 |
dc.date.issued.fl_str_mv |
2006-04-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T12:41:02Z |
dc.date.available.fl_str_mv |
2016-01-24T12:41:02Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Eye. London: Nature Publishing Group, v. 20, n. 4, p. 431-439, 2006. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/28798 http://dx.doi.org/10.1038/sj.eye.6701896 |
dc.identifier.issn.none.fl_str_mv |
0950-222X |
dc.identifier.doi.none.fl_str_mv |
10.1038/sj.eye.6701896 |
dc.identifier.wos.none.fl_str_mv |
WOS:000236561100006 |
identifier_str_mv |
Eye. London: Nature Publishing Group, v. 20, n. 4, p. 431-439, 2006. 0950-222X 10.1038/sj.eye.6701896 WOS:000236561100006 |
url |
http://repositorio.unifesp.br/handle/11600/28798 http://dx.doi.org/10.1038/sj.eye.6701896 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Eye |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
431-439 |
dc.publisher.none.fl_str_mv |
Nature Publishing Group |
publisher.none.fl_str_mv |
Nature Publishing Group |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
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