Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/37180 http://dx.doi.org/10.2147/NDT.S49071 |
Resumo: | Background: Attention deficit hyperactivity disorder (ADHD) is characterized by decreased attention span, impulsiveness, and hyperactivity. Autonomic nervous system imbalance was previously described in this population. We aim to compare the autonomic function of children with ADHD and controls by analyzing heart rate variability (HRV).Methods: Children rested in supine position with spontaneous breathing for 20 minutes. Heart rate was recorded beat by beat. HRV analysis was performed in the time and frequency domains and Poincare plot.Results: Twenty-eight children with ADHD (22 boys, aged 9.964 years) and 28 controls (15 boys, age 9.857 years) participated in this study. It was determined that the mean and standard deviation of indexes which indicate parasympathetic activity is higher in children with ADHD than in children without the disorder: high frequency in normalized units, 46.182 (14.159) versus 40.632 (12.247); root mean square of successive differences, 41.821 (17.834) versus 38.150 (18.357); differences between adjacent normal-to-normal intervals greater than 50 milliseconds, 199.75 (144.00) versus 127.46 (102.21) (P<0.05); percentage of differences between adjacent normal-to-normal intervals greater than 50 milliseconds, 23.957 (17.316) versus 16.211 (13.215); standard deviation of instantaneous beat-to-beat interval, 29.586 (12.622) versus 26.989 (12.983).Conclusion: Comparison of the autonomic function by analyzing HRV suggests an increase in the activity of the parasympathetic autonomic nervous systems in children with ADHD in relation to the control group. |
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Carvalho, Tatiana Dias de [UNIFESP]Wajnsztejn, RubensAbreu, Luiz Carlos deVanderlei, Luiz Carlos MarquesGodoy, Moacir FernandesAdami, FernandoValenti, Vitor Engrácia [UNIFESP]Monteiro, Carlos B. M.Leone, ClaudioMartins, Karen Cristina da CruzFerreira, Celso [UNIFESP]Universidade Federal de São Paulo (UNIFESP)FMABCUniv Estadual PaulistaUniversidade de São Paulo (USP)2016-01-24T14:34:58Z2016-01-24T14:34:58Z2014-01-01Neuropsychiatric Disease and Treatment. Albany: Dove Medical Press Ltd, v. 10, p. 613-618, 2014.1176-6328http://repositorio.unifesp.br/handle/11600/37180http://dx.doi.org/10.2147/NDT.S4907110.2147/NDT.S49071WOS:000334318500001Background: Attention deficit hyperactivity disorder (ADHD) is characterized by decreased attention span, impulsiveness, and hyperactivity. Autonomic nervous system imbalance was previously described in this population. We aim to compare the autonomic function of children with ADHD and controls by analyzing heart rate variability (HRV).Methods: Children rested in supine position with spontaneous breathing for 20 minutes. Heart rate was recorded beat by beat. HRV analysis was performed in the time and frequency domains and Poincare plot.Results: Twenty-eight children with ADHD (22 boys, aged 9.964 years) and 28 controls (15 boys, age 9.857 years) participated in this study. It was determined that the mean and standard deviation of indexes which indicate parasympathetic activity is higher in children with ADHD than in children without the disorder: high frequency in normalized units, 46.182 (14.159) versus 40.632 (12.247); root mean square of successive differences, 41.821 (17.834) versus 38.150 (18.357); differences between adjacent normal-to-normal intervals greater than 50 milliseconds, 199.75 (144.00) versus 127.46 (102.21) (P<0.05); percentage of differences between adjacent normal-to-normal intervals greater than 50 milliseconds, 23.957 (17.316) versus 16.211 (13.215); standard deviation of instantaneous beat-to-beat interval, 29.586 (12.622) versus 26.989 (12.983).Conclusion: Comparison of the autonomic function by analyzing HRV suggests an increase in the activity of the parasympathetic autonomic nervous systems in children with ADHD in relation to the control group.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Federal de São Paulo, UNIFESP, Disciplina Cardiol, Dept Med, São Paulo, BrazilFMABC, Fac Med ABC, Lab Escrita Cient, Santo Andre, BrazilFMABC, Fac Med ABC, Programa Posgrad Ciencias Saude, Nucl Especializado Aprendizagem, Santo Andre, BrazilUniv Estadual Paulista, UNESP, Fac Ciencias & Tecnol, Dept Fisioterapia, São Paulo, BrazilFAMERP, Fac Med Sao Jose de Rio Preto, Nucleo Transdisciplinar Estudos Caos & Complexida, Sao Jose Do Rio Preto, BrazilUniv Estadual Paulista, UNESP, Fac Filosofia & Ciencias, Dept Fonoaudiol, Marilia, BrazilUniv São Paulo, Fac Saude Publ, Dept Saude Maternoinfantil, São Paulo, BrazilUniversidade Federal de São Paulo, UNIFESP, Disciplina Cardiol, Dept Med, São Paulo, BrazilFAPESP: 2013/17628-2Web of Science613-618engDove Medical Press LtdNeuropsychiatric Disease and Treatmentattention deficit hyperactivity disorderautonomic nervous systemChildrenheart rate variabilityAnalysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorderinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/371802022-09-27 11:18:59.696metadata only accessoai:repositorio.unifesp.br:11600/37180Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:25:28.671757Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder |
title |
Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder |
spellingShingle |
Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder Carvalho, Tatiana Dias de [UNIFESP] attention deficit hyperactivity disorder autonomic nervous system Children heart rate variability |
title_short |
Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder |
title_full |
Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder |
title_fullStr |
Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder |
title_full_unstemmed |
Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder |
title_sort |
Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder |
author |
Carvalho, Tatiana Dias de [UNIFESP] |
author_facet |
Carvalho, Tatiana Dias de [UNIFESP] Wajnsztejn, Rubens Abreu, Luiz Carlos de Vanderlei, Luiz Carlos Marques Godoy, Moacir Fernandes Adami, Fernando Valenti, Vitor Engrácia [UNIFESP] Monteiro, Carlos B. M. Leone, Claudio Martins, Karen Cristina da Cruz Ferreira, Celso [UNIFESP] |
author_role |
author |
author2 |
Wajnsztejn, Rubens Abreu, Luiz Carlos de Vanderlei, Luiz Carlos Marques Godoy, Moacir Fernandes Adami, Fernando Valenti, Vitor Engrácia [UNIFESP] Monteiro, Carlos B. M. Leone, Claudio Martins, Karen Cristina da Cruz Ferreira, Celso [UNIFESP] |
author2_role |
author author author author author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) FMABC Univ Estadual Paulista Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Carvalho, Tatiana Dias de [UNIFESP] Wajnsztejn, Rubens Abreu, Luiz Carlos de Vanderlei, Luiz Carlos Marques Godoy, Moacir Fernandes Adami, Fernando Valenti, Vitor Engrácia [UNIFESP] Monteiro, Carlos B. M. Leone, Claudio Martins, Karen Cristina da Cruz Ferreira, Celso [UNIFESP] |
dc.subject.eng.fl_str_mv |
attention deficit hyperactivity disorder autonomic nervous system Children heart rate variability |
topic |
attention deficit hyperactivity disorder autonomic nervous system Children heart rate variability |
description |
Background: Attention deficit hyperactivity disorder (ADHD) is characterized by decreased attention span, impulsiveness, and hyperactivity. Autonomic nervous system imbalance was previously described in this population. We aim to compare the autonomic function of children with ADHD and controls by analyzing heart rate variability (HRV).Methods: Children rested in supine position with spontaneous breathing for 20 minutes. Heart rate was recorded beat by beat. HRV analysis was performed in the time and frequency domains and Poincare plot.Results: Twenty-eight children with ADHD (22 boys, aged 9.964 years) and 28 controls (15 boys, age 9.857 years) participated in this study. It was determined that the mean and standard deviation of indexes which indicate parasympathetic activity is higher in children with ADHD than in children without the disorder: high frequency in normalized units, 46.182 (14.159) versus 40.632 (12.247); root mean square of successive differences, 41.821 (17.834) versus 38.150 (18.357); differences between adjacent normal-to-normal intervals greater than 50 milliseconds, 199.75 (144.00) versus 127.46 (102.21) (P<0.05); percentage of differences between adjacent normal-to-normal intervals greater than 50 milliseconds, 23.957 (17.316) versus 16.211 (13.215); standard deviation of instantaneous beat-to-beat interval, 29.586 (12.622) versus 26.989 (12.983).Conclusion: Comparison of the autonomic function by analyzing HRV suggests an increase in the activity of the parasympathetic autonomic nervous systems in children with ADHD in relation to the control group. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014-01-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T14:34:58Z |
dc.date.available.fl_str_mv |
2016-01-24T14:34:58Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Neuropsychiatric Disease and Treatment. Albany: Dove Medical Press Ltd, v. 10, p. 613-618, 2014. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/37180 http://dx.doi.org/10.2147/NDT.S49071 |
dc.identifier.issn.none.fl_str_mv |
1176-6328 |
dc.identifier.doi.none.fl_str_mv |
10.2147/NDT.S49071 |
dc.identifier.wos.none.fl_str_mv |
WOS:000334318500001 |
identifier_str_mv |
Neuropsychiatric Disease and Treatment. Albany: Dove Medical Press Ltd, v. 10, p. 613-618, 2014. 1176-6328 10.2147/NDT.S49071 WOS:000334318500001 |
url |
http://repositorio.unifesp.br/handle/11600/37180 http://dx.doi.org/10.2147/NDT.S49071 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Neuropsychiatric Disease and Treatment |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
613-618 |
dc.publisher.none.fl_str_mv |
Dove Medical Press Ltd |
publisher.none.fl_str_mv |
Dove Medical Press Ltd |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
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1783460288850296832 |