Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://repositorio.unifesp.br/handle/11600/57000 http://dx.doi.org/10.1016/j.rmed.2016.08.013 |
Resumo: | Background: Bronchodilator response (BDR) analyzed by the raised volume rapid thoracic compression (RVRTC) in wheezing infants is not yet well described, although bronchodilators (BD) are routine in the treatment of this population. Objective: To evaluate BDR by RVRTC technique in infants with recurrent wheezing and compare to control group. Method: Cross sectional study, 45 infants, age 56 weeks (38-67 weeks). Two groups: wheezing group (WG: history of recurrent wheezing) and control group (CG). RVRTC was evaluated, FVC, FEV0.5, FEF50, FEF75, FEF85, FEF25-75 were measured. Salbutamol was delivered to infants and RVRTC evaluated again. BDR was determined by the increase greater than two standard deviation from the mean change in the CG. Results: In WG (n = 32) lung function was worse than in CG (n = 13): FEV0.5: 0.0(-0.9-0.9z score) vs 0.8(0.2-1.4z score) |
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Lanza, Fernanda Cordoba [UNIFESP]Wandalsen, Gustavo Falbo [UNIFESP]Dos Santos, Amelia Miyashiro [UNIFESP]Solé, Dirceu [UNIFESP]2020-07-31T12:47:41Z2020-07-31T12:47:41Z2016Respiratory Medicine. London, v. 119, p. 29-34, 2016.0954-6111https://repositorio.unifesp.br/handle/11600/57000http://dx.doi.org/10.1016/j.rmed.2016.08.01310.1016/j.rmed.2016.08.013WOS:000385321200006Background: Bronchodilator response (BDR) analyzed by the raised volume rapid thoracic compression (RVRTC) in wheezing infants is not yet well described, although bronchodilators (BD) are routine in the treatment of this population. Objective: To evaluate BDR by RVRTC technique in infants with recurrent wheezing and compare to control group. Method: Cross sectional study, 45 infants, age 56 weeks (38-67 weeks). Two groups: wheezing group (WG: history of recurrent wheezing) and control group (CG). RVRTC was evaluated, FVC, FEV0.5, FEF50, FEF75, FEF85, FEF25-75 were measured. Salbutamol was delivered to infants and RVRTC evaluated again. BDR was determined by the increase greater than two standard deviation from the mean change in the CG. Results: In WG (n = 32) lung function was worse than in CG (n = 13): FEV0.5: 0.0(-0.9-0.9z score) vs 0.8(0.2-1.4z score)FEF50: 0.2(-0.3-1.1z score) vs 0.9(0.5-1.4z score)and FEF25-75: 0.2(-0.5-1.1z score) vs 1.1(0.6-1.6z score), respectively, p < 0.05. Both groups had similar increase after BD. In WG 11 patients (34%) were responder and these had worse lung function compared to nonresponder (n = 21) (p < 0.05). The increase in lung function after BD in responder was higher than in nonresponder: FEV0.5: 6.5(2.1-7.1%) vs -0.5(-2.5-0.7%), FEF50: 5.1(2.7-11.7%) vs 0.4(-1.1-2.8%), FEF75: 20.7(4.7-23.6%) vs -1.3(-6.4-3.9%), FEF25-75: 9.9(3.8-16.4%) vs 0.0(-1.5-1.0%), respectively, p < 0.05. Conclusion: 34% WG showed BDR measured by the RVRTC. The best variables to detect BDR were FEF75, FEF25-75 and FEV0.5. Patients with worse lung function showed better response to BD. (C) 2016 Elsevier Ltd. All rights reserved.Fed Univ Sao Paulo UNIFESP, Dept Pediat, Discipline Allergy Clin Immunol & Rheumatol, Otonis St 725, BR-04025002 Sao Paulo, SP, BrazilFed Univ Sao Paulo UNIFESP, Dept Pediat, Neonatal Div Med, Marselhesa St 630, BR-04020060 Sao Paulo, SP, BrazilDiscipline of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Universidade Federal de São Paulo (UNIFESP), Sao Paulo, SP, Otonis St 725, 04025-002, BrazilNeonatal Division of Medicine – Department of Pediatrics – Universidade Federal de São Paulo (UNIFESP), Sao Paulo, SP, Marselhesa St 630, 04020-060, BrazilWeb of Science29-34engW B Saunders Co LtdRespiratory MedicineLung functionWheezingInfantsBronchodilatorBronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression techniqueinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleLondon119info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/570002022-02-07 20:58:45.759metadata only accessoai:repositorio.unifesp.br:11600/57000Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:08:09.732515Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique |
title |
Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique |
spellingShingle |
Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique Lanza, Fernanda Cordoba [UNIFESP] Lung function Wheezing Infants Bronchodilator |
title_short |
Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique |
title_full |
Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique |
title_fullStr |
Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique |
title_full_unstemmed |
Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique |
title_sort |
Bronchodilator response in wheezing infants assessed by the raised volume rapid thoracic compression technique |
author |
Lanza, Fernanda Cordoba [UNIFESP] |
author_facet |
Lanza, Fernanda Cordoba [UNIFESP] Wandalsen, Gustavo Falbo [UNIFESP] Dos Santos, Amelia Miyashiro [UNIFESP] Solé, Dirceu [UNIFESP] |
author_role |
author |
author2 |
Wandalsen, Gustavo Falbo [UNIFESP] Dos Santos, Amelia Miyashiro [UNIFESP] Solé, Dirceu [UNIFESP] |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Lanza, Fernanda Cordoba [UNIFESP] Wandalsen, Gustavo Falbo [UNIFESP] Dos Santos, Amelia Miyashiro [UNIFESP] Solé, Dirceu [UNIFESP] |
dc.subject.eng.fl_str_mv |
Lung function Wheezing Infants Bronchodilator |
topic |
Lung function Wheezing Infants Bronchodilator |
description |
Background: Bronchodilator response (BDR) analyzed by the raised volume rapid thoracic compression (RVRTC) in wheezing infants is not yet well described, although bronchodilators (BD) are routine in the treatment of this population. Objective: To evaluate BDR by RVRTC technique in infants with recurrent wheezing and compare to control group. Method: Cross sectional study, 45 infants, age 56 weeks (38-67 weeks). Two groups: wheezing group (WG: history of recurrent wheezing) and control group (CG). RVRTC was evaluated, FVC, FEV0.5, FEF50, FEF75, FEF85, FEF25-75 were measured. Salbutamol was delivered to infants and RVRTC evaluated again. BDR was determined by the increase greater than two standard deviation from the mean change in the CG. Results: In WG (n = 32) lung function was worse than in CG (n = 13): FEV0.5: 0.0(-0.9-0.9z score) vs 0.8(0.2-1.4z score) |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2020-07-31T12:47:41Z |
dc.date.available.fl_str_mv |
2020-07-31T12:47:41Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Respiratory Medicine. London, v. 119, p. 29-34, 2016. |
dc.identifier.uri.fl_str_mv |
https://repositorio.unifesp.br/handle/11600/57000 http://dx.doi.org/10.1016/j.rmed.2016.08.013 |
dc.identifier.issn.none.fl_str_mv |
0954-6111 |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.rmed.2016.08.013 |
dc.identifier.wos.none.fl_str_mv |
WOS:000385321200006 |
identifier_str_mv |
Respiratory Medicine. London, v. 119, p. 29-34, 2016. 0954-6111 10.1016/j.rmed.2016.08.013 WOS:000385321200006 |
url |
https://repositorio.unifesp.br/handle/11600/57000 http://dx.doi.org/10.1016/j.rmed.2016.08.013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Respiratory Medicine |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
29-34 |
dc.coverage.none.fl_str_mv |
London |
dc.publisher.none.fl_str_mv |
W B Saunders Co Ltd |
publisher.none.fl_str_mv |
W B Saunders Co Ltd |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
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