Coronary artery and myocardial inflammatory reaction induced by intracoronary stent
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/27446 http://dx.doi.org/10.1016/S0003-4975(03)00872-5 |
Resumo: | Background. Intracoronary stents have been extensively used in percutaneous coronary revascularization. However, despite the breakthroughs and developments associated with this new technology, novel complications and findings have emerged compelling the cardiac surgeon to cope with this new scenario. the presence of an intracoronary foreign body (stent) might induce an inflammatory reaction to the coronary artery and surrounding cardiac muscle.Methods. Six patients who previously (2 to 72 weeks) underwent stent insertion and subsequently coronary artery bypass graft surgery had a biopsy taken from the grafted coronary artery distal. to the stent and from the adjacent muscle. the samples were processed and stained with hematoxylin and eosin and histologically studied.Results. Histologic examination of the coronary artery distal to the stent revealed chronic inflammation and an intimal acute inflammatory infiltrate, with polymorphonuclear leukocytes. the myocardium adjacent to the stent exhibited a significant chronic inflammatory infiltrate and fibrosis, compatible with myocarditis.Conclusions. the presence of an intracoronary stent induces a persistent, acute and chronic inflammatory reaction, with involvement of the distal. coronary artery and surrounding myocardium. This may have implications when choosing the optimal site distal to the stent for coronary artery bypass grafting. (C) 2003 by the Society of Thoracic Surgeons. |
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Gomes, Walter J. [UNIFESP]Giannotti Filho, Osvaldo [UNIFESP]Paez, Rodrigo P. [UNIFESP]Hossne, Nelson A. [UNIFESP]Catani, Roberto [UNIFESP]Buffolo, Enio [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2016-01-24T12:34:05Z2016-01-24T12:34:05Z2003-11-01Annals of Thoracic Surgery. New York: Elsevier B.V., v. 76, n. 5, p. 1528-1532, 2003.0003-4975http://repositorio.unifesp.br/handle/11600/27446http://dx.doi.org/10.1016/S0003-4975(03)00872-510.1016/S0003-4975(03)00872-5WOS:000186358600034Background. Intracoronary stents have been extensively used in percutaneous coronary revascularization. However, despite the breakthroughs and developments associated with this new technology, novel complications and findings have emerged compelling the cardiac surgeon to cope with this new scenario. the presence of an intracoronary foreign body (stent) might induce an inflammatory reaction to the coronary artery and surrounding cardiac muscle.Methods. Six patients who previously (2 to 72 weeks) underwent stent insertion and subsequently coronary artery bypass graft surgery had a biopsy taken from the grafted coronary artery distal. to the stent and from the adjacent muscle. the samples were processed and stained with hematoxylin and eosin and histologically studied.Results. Histologic examination of the coronary artery distal to the stent revealed chronic inflammation and an intimal acute inflammatory infiltrate, with polymorphonuclear leukocytes. the myocardium adjacent to the stent exhibited a significant chronic inflammatory infiltrate and fibrosis, compatible with myocarditis.Conclusions. the presence of an intracoronary stent induces a persistent, acute and chronic inflammatory reaction, with involvement of the distal. coronary artery and surrounding myocardium. This may have implications when choosing the optimal site distal to the stent for coronary artery bypass grafting. (C) 2003 by the Society of Thoracic Surgeons.Universidade Federal de São Paulo, Escola Paulista Med, Cardiovasc Surg Discipline, BR-04023900 São Paulo, SP, BrazilUniversidade Federal de São Paulo, São Paulo Hosp, BR-04023900 São Paulo, SP, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Cardiovasc Surg Discipline, BR-04023900 São Paulo, SP, BrazilUniversidade Federal de São Paulo, São Paulo Hosp, BR-04023900 São Paulo, SP, BrazilWeb of Science1528-1532engElsevier B.V.Annals of Thoracic Surgeryhttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyinfo:eu-repo/semantics/openAccessCoronary artery and myocardial inflammatory reaction induced by intracoronary stentinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlereponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/274462022-11-03 15:00:31.566metadata only accessoai:repositorio.unifesp.br:11600/27446Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:28:07.827915Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Coronary artery and myocardial inflammatory reaction induced by intracoronary stent |
title |
Coronary artery and myocardial inflammatory reaction induced by intracoronary stent |
spellingShingle |
Coronary artery and myocardial inflammatory reaction induced by intracoronary stent Gomes, Walter J. [UNIFESP] |
title_short |
Coronary artery and myocardial inflammatory reaction induced by intracoronary stent |
title_full |
Coronary artery and myocardial inflammatory reaction induced by intracoronary stent |
title_fullStr |
Coronary artery and myocardial inflammatory reaction induced by intracoronary stent |
title_full_unstemmed |
Coronary artery and myocardial inflammatory reaction induced by intracoronary stent |
title_sort |
Coronary artery and myocardial inflammatory reaction induced by intracoronary stent |
author |
Gomes, Walter J. [UNIFESP] |
author_facet |
Gomes, Walter J. [UNIFESP] Giannotti Filho, Osvaldo [UNIFESP] Paez, Rodrigo P. [UNIFESP] Hossne, Nelson A. [UNIFESP] Catani, Roberto [UNIFESP] Buffolo, Enio [UNIFESP] |
author_role |
author |
author2 |
Giannotti Filho, Osvaldo [UNIFESP] Paez, Rodrigo P. [UNIFESP] Hossne, Nelson A. [UNIFESP] Catani, Roberto [UNIFESP] Buffolo, Enio [UNIFESP] |
author2_role |
author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Gomes, Walter J. [UNIFESP] Giannotti Filho, Osvaldo [UNIFESP] Paez, Rodrigo P. [UNIFESP] Hossne, Nelson A. [UNIFESP] Catani, Roberto [UNIFESP] Buffolo, Enio [UNIFESP] |
description |
Background. Intracoronary stents have been extensively used in percutaneous coronary revascularization. However, despite the breakthroughs and developments associated with this new technology, novel complications and findings have emerged compelling the cardiac surgeon to cope with this new scenario. the presence of an intracoronary foreign body (stent) might induce an inflammatory reaction to the coronary artery and surrounding cardiac muscle.Methods. Six patients who previously (2 to 72 weeks) underwent stent insertion and subsequently coronary artery bypass graft surgery had a biopsy taken from the grafted coronary artery distal. to the stent and from the adjacent muscle. the samples were processed and stained with hematoxylin and eosin and histologically studied.Results. Histologic examination of the coronary artery distal to the stent revealed chronic inflammation and an intimal acute inflammatory infiltrate, with polymorphonuclear leukocytes. the myocardium adjacent to the stent exhibited a significant chronic inflammatory infiltrate and fibrosis, compatible with myocarditis.Conclusions. the presence of an intracoronary stent induces a persistent, acute and chronic inflammatory reaction, with involvement of the distal. coronary artery and surrounding myocardium. This may have implications when choosing the optimal site distal to the stent for coronary artery bypass grafting. (C) 2003 by the Society of Thoracic Surgeons. |
publishDate |
2003 |
dc.date.issued.fl_str_mv |
2003-11-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T12:34:05Z |
dc.date.available.fl_str_mv |
2016-01-24T12:34:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Annals of Thoracic Surgery. New York: Elsevier B.V., v. 76, n. 5, p. 1528-1532, 2003. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/27446 http://dx.doi.org/10.1016/S0003-4975(03)00872-5 |
dc.identifier.issn.none.fl_str_mv |
0003-4975 |
dc.identifier.doi.none.fl_str_mv |
10.1016/S0003-4975(03)00872-5 |
dc.identifier.wos.none.fl_str_mv |
WOS:000186358600034 |
identifier_str_mv |
Annals of Thoracic Surgery. New York: Elsevier B.V., v. 76, n. 5, p. 1528-1532, 2003. 0003-4975 10.1016/S0003-4975(03)00872-5 WOS:000186358600034 |
url |
http://repositorio.unifesp.br/handle/11600/27446 http://dx.doi.org/10.1016/S0003-4975(03)00872-5 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Annals of Thoracic Surgery |
dc.rights.driver.fl_str_mv |
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1528-1532 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
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1783460294830325760 |