Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães

Detalhes bibliográficos
Autor(a) principal: Carvalho, Rogério Oliva
Data de Publicação: 2004
Tipo de documento: Dissertação
Idioma: por
Título da fonte: LOCUS Repositório Institucional da UFV
Texto Completo: http://locus.ufv.br/handle/123456789/5039
Resumo: The objective of this work was to evaluate the individual efficacy of the fenbendazole and the pyrantel pamoate against intestinal nematodes of dogs. Thirty six nestlings of dogs were used, being eighteen males and eighteen females up to six months of age, coming of the kennel of the Department of Veterinary Medicine of the Federal University of Viçosa, selected through fecal exams of Willis, simple sedimentation and count of eggs per gram of feces (EPG). being used the animals that presented mixed infection for Ancylostoma sp. and Toxocara canis. The animais were distributed in three groups of twelve animals, being a control group, a group treated with fenbendazole, 100 mg for Kg of body weight, orally, in an unique dose, and the other with pyrantel pamoate, 5 mg for Kg of body weight, orally, in an unique dose. During the whole experimental period, the dogs received commercial ration and water ad libitum . Fecal exams of Willis, simple sedimentation and EPG realized in the day of the treatment (0), 24 hours after the treatments (1) and in the 3, 5 and 7 after the treatments. In the seventh day, the animals were killed and necropsied for collection of the adult worms and the mucosa of the gastrointestinal tract was submitted to digestion process, in hydrochloric acid to 3%, for research of immature stages. The results showed an efficacy of 99,89% of the pyrantel pamoate against the A. caninum with reduction of 100% of EPG in the seventh day after the treatment, and against the T. canis the effectiveness was of 71,65%, with reduction of 80,73% of OPG. The fenbendazole showed an efficacy of 93,19% against the A. caninum, with reduction of 96,22% in the EPG and an efficacy of 82,1% against the T. canis, reducing the EPG in 95,71%. The results demonstrate the efficacy for the control of the A. caninum with the two drugs, with higher effective of the pyrantel pamoate. To the T. canis control the drugs shower lower efficacy when administered separately in the doses recommended commercially.
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spelling Carvalho, Rogério Olivahttp://lattes.cnpq.br/6226293652248977Araújo, Jackson Victor dehttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4780836D6Salcedo, Joaquín Hernán Patarroyohttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4783313T4Pompermayer, Luiz Gonzagahttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4769212Z2Guimarães, Marcos Pezzihttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4783034Y8Viana, José Antoniohttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4797107Y82015-03-26T13:46:53Z2007-01-222015-03-26T13:46:53Z2004-12-15CARVALHO, Rogério Oliva. Efficacy of fenbendazole and of pyrantel pamoato on Ancylostoma sp. e Toxocara canis, parasites intestinal of dogs. 2004. 43 f. Dissertação (Mestrado em Biotecnologia, diagnóstico e controle de doenças; Epidemiologia e controle de qualidade de prod. de) - Universidade Federal de Viçosa, Viçosa, 2004.http://locus.ufv.br/handle/123456789/5039The objective of this work was to evaluate the individual efficacy of the fenbendazole and the pyrantel pamoate against intestinal nematodes of dogs. Thirty six nestlings of dogs were used, being eighteen males and eighteen females up to six months of age, coming of the kennel of the Department of Veterinary Medicine of the Federal University of Viçosa, selected through fecal exams of Willis, simple sedimentation and count of eggs per gram of feces (EPG). being used the animals that presented mixed infection for Ancylostoma sp. and Toxocara canis. The animais were distributed in three groups of twelve animals, being a control group, a group treated with fenbendazole, 100 mg for Kg of body weight, orally, in an unique dose, and the other with pyrantel pamoate, 5 mg for Kg of body weight, orally, in an unique dose. During the whole experimental period, the dogs received commercial ration and water ad libitum . Fecal exams of Willis, simple sedimentation and EPG realized in the day of the treatment (0), 24 hours after the treatments (1) and in the 3, 5 and 7 after the treatments. In the seventh day, the animals were killed and necropsied for collection of the adult worms and the mucosa of the gastrointestinal tract was submitted to digestion process, in hydrochloric acid to 3%, for research of immature stages. The results showed an efficacy of 99,89% of the pyrantel pamoate against the A. caninum with reduction of 100% of EPG in the seventh day after the treatment, and against the T. canis the effectiveness was of 71,65%, with reduction of 80,73% of OPG. The fenbendazole showed an efficacy of 93,19% against the A. caninum, with reduction of 96,22% in the EPG and an efficacy of 82,1% against the T. canis, reducing the EPG in 95,71%. The results demonstrate the efficacy for the control of the A. caninum with the two drugs, with higher effective of the pyrantel pamoate. To the T. canis control the drugs shower lower efficacy when administered separately in the doses recommended commercially.Este trabalho teve como objetivo avaliar a eficácia individual do fembendazol e do pamoato de pirantel contra nematóides intestinais de cães. Para tal, foram utilizados 36 filhotes de cães, sendo 18 machos e 18 fêmeas com menos de seis meses de idade , provenientes do canil do Departamento de Veterinária da Universidade Federal de Viçosa, selecionados por meio de exames coprológicos de Willis, sedimentação simples e contagem de ovos por grama de fezes (OPG). Foram utilizados os animais que apresentaram infecção mista por Ancylostoma sp. e Toxocara canis. Estes foram distribuídos em três grupos de doze animais, sendo um grupo controle, um tratado com fembendazol, 100 mg por Kg de peso vivo, por via oral, em dose única, e o outro com pamoato de pirantel, 15mg por Kg de peso vivo, por via oral, em dose única. Durante todo o período experimental, os cães receberam ração comercial e água à vontade. Foram realizados exames coprológicos de Willis, sedimentação simples e contagem de ovos por grama de fezes (OPG), no dia do tratamento (dia 0), 24 horas após os tratamentos (dia 1) e nos dias 3, 5 e 7 pós-tratamento. No sétimo dia, os animais foram sacrificados e necropsiados para coleta dos vermes adultos e as mucosas do trato gastrintestinal passaram por um processo de digestão, em acido clorídrico a 3%, para pesquisa de estádios imaturos. Os resultados obtidos mostraram que houve uma eficácia de 99,89% do pamoato de pirantel contra o A. caninum e uma redução de 100% do OPG no sétimo dia após o tratamento, já contra o T. canis a eficácia foi de 71,63%, com redução de 80,73% do OPG. O fembendazol apresentou uma eficácia de 93,19% contra o A. caninum, com redução de 96,22% do OPG e uma eficácia de 82,1% contra o T. canis, reduzindo o OPG em 95,71%. Para o controle do A. caninum, as duas drogas se mostraram eficazes, com maior eficácia do pamoato de pirantel, mas, para o T. canis as drogas foram pouco eficazes quando administrados isoladamente nas doses comercialmente recomendadas.application/pdfporUniversidade Federal de ViçosaMestrado em Medicina VeterináriaUFVBRBiotecnologia, diagnóstico e controle de doenças; Epidemiologia e controle de qualidade de prod. deCãoIntestinoDoençasDogIntestinesDiseasesCNPQ::CIENCIAS BIOLOGICAS::PARASITOLOGIAEficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cãesEfficacy of fenbendazole and of pyrantel pamoato on Ancylostoma sp. e Toxocara canis, parasites intestinal of dogsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:LOCUS Repositório Institucional da UFVinstname:Universidade Federal de Viçosa (UFV)instacron:UFVORIGINALtexto completo.pdfapplication/pdf126733https://locus.ufv.br//bitstream/123456789/5039/1/texto%20completo.pdfaf1fa3f739aff7ae6ddf9eed2f8af7f2MD51TEXTtexto completo.pdf.txttexto completo.pdf.txtExtracted texttext/plain65560https://locus.ufv.br//bitstream/123456789/5039/2/texto%20completo.pdf.txt272fd1232d727a4d520c23b80cf588c6MD52THUMBNAILtexto completo.pdf.jpgtexto completo.pdf.jpgIM Thumbnailimage/jpeg3588https://locus.ufv.br//bitstream/123456789/5039/3/texto%20completo.pdf.jpgffd8b9ef96767ee60901e18bbd05a60fMD53123456789/50392016-04-11 23:08:25.271oai:locus.ufv.br:123456789/5039Repositório InstitucionalPUBhttps://www.locus.ufv.br/oai/requestfabiojreis@ufv.bropendoar:21452016-04-12T02:08:25LOCUS Repositório Institucional da UFV - Universidade Federal de Viçosa (UFV)false
dc.title.por.fl_str_mv Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães
dc.title.alternative.eng.fl_str_mv Efficacy of fenbendazole and of pyrantel pamoato on Ancylostoma sp. e Toxocara canis, parasites intestinal of dogs
title Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães
spellingShingle Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães
Carvalho, Rogério Oliva
Cão
Intestino
Doenças
Dog
Intestines
Diseases
CNPQ::CIENCIAS BIOLOGICAS::PARASITOLOGIA
title_short Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães
title_full Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães
title_fullStr Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães
title_full_unstemmed Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães
title_sort Eficácia do fembendazol e do pamoato de pirantel sobre Ancylostoma sp. e Toxocara canis, parasitos intestinais de cães
author Carvalho, Rogério Oliva
author_facet Carvalho, Rogério Oliva
author_role author
dc.contributor.authorLattes.por.fl_str_mv http://lattes.cnpq.br/6226293652248977
dc.contributor.author.fl_str_mv Carvalho, Rogério Oliva
dc.contributor.advisor1.fl_str_mv Araújo, Jackson Victor de
dc.contributor.advisor1Lattes.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4780836D6
dc.contributor.referee1.fl_str_mv Salcedo, Joaquín Hernán Patarroyo
dc.contributor.referee1Lattes.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4783313T4
dc.contributor.referee2.fl_str_mv Pompermayer, Luiz Gonzaga
dc.contributor.referee2Lattes.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4769212Z2
dc.contributor.referee3.fl_str_mv Guimarães, Marcos Pezzi
dc.contributor.referee3Lattes.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4783034Y8
dc.contributor.referee4.fl_str_mv Viana, José Antonio
dc.contributor.referee4Lattes.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4797107Y8
contributor_str_mv Araújo, Jackson Victor de
Salcedo, Joaquín Hernán Patarroyo
Pompermayer, Luiz Gonzaga
Guimarães, Marcos Pezzi
Viana, José Antonio
dc.subject.por.fl_str_mv Cão
Intestino
Doenças
topic Cão
Intestino
Doenças
Dog
Intestines
Diseases
CNPQ::CIENCIAS BIOLOGICAS::PARASITOLOGIA
dc.subject.eng.fl_str_mv Dog
Intestines
Diseases
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS BIOLOGICAS::PARASITOLOGIA
description The objective of this work was to evaluate the individual efficacy of the fenbendazole and the pyrantel pamoate against intestinal nematodes of dogs. Thirty six nestlings of dogs were used, being eighteen males and eighteen females up to six months of age, coming of the kennel of the Department of Veterinary Medicine of the Federal University of Viçosa, selected through fecal exams of Willis, simple sedimentation and count of eggs per gram of feces (EPG). being used the animals that presented mixed infection for Ancylostoma sp. and Toxocara canis. The animais were distributed in three groups of twelve animals, being a control group, a group treated with fenbendazole, 100 mg for Kg of body weight, orally, in an unique dose, and the other with pyrantel pamoate, 5 mg for Kg of body weight, orally, in an unique dose. During the whole experimental period, the dogs received commercial ration and water ad libitum . Fecal exams of Willis, simple sedimentation and EPG realized in the day of the treatment (0), 24 hours after the treatments (1) and in the 3, 5 and 7 after the treatments. In the seventh day, the animals were killed and necropsied for collection of the adult worms and the mucosa of the gastrointestinal tract was submitted to digestion process, in hydrochloric acid to 3%, for research of immature stages. The results showed an efficacy of 99,89% of the pyrantel pamoate against the A. caninum with reduction of 100% of EPG in the seventh day after the treatment, and against the T. canis the effectiveness was of 71,65%, with reduction of 80,73% of OPG. The fenbendazole showed an efficacy of 93,19% against the A. caninum, with reduction of 96,22% in the EPG and an efficacy of 82,1% against the T. canis, reducing the EPG in 95,71%. The results demonstrate the efficacy for the control of the A. caninum with the two drugs, with higher effective of the pyrantel pamoate. To the T. canis control the drugs shower lower efficacy when administered separately in the doses recommended commercially.
publishDate 2004
dc.date.issued.fl_str_mv 2004-12-15
dc.date.available.fl_str_mv 2007-01-22
2015-03-26T13:46:53Z
dc.date.accessioned.fl_str_mv 2015-03-26T13:46:53Z
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dc.identifier.citation.fl_str_mv CARVALHO, Rogério Oliva. Efficacy of fenbendazole and of pyrantel pamoato on Ancylostoma sp. e Toxocara canis, parasites intestinal of dogs. 2004. 43 f. Dissertação (Mestrado em Biotecnologia, diagnóstico e controle de doenças; Epidemiologia e controle de qualidade de prod. de) - Universidade Federal de Viçosa, Viçosa, 2004.
dc.identifier.uri.fl_str_mv http://locus.ufv.br/handle/123456789/5039
identifier_str_mv CARVALHO, Rogério Oliva. Efficacy of fenbendazole and of pyrantel pamoato on Ancylostoma sp. e Toxocara canis, parasites intestinal of dogs. 2004. 43 f. Dissertação (Mestrado em Biotecnologia, diagnóstico e controle de doenças; Epidemiologia e controle de qualidade de prod. de) - Universidade Federal de Viçosa, Viçosa, 2004.
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