Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil
Main Author: | |
---|---|
Publication Date: | 2013 |
Other Authors: | , , , |
Format: | Article |
Language: | eng |
Source: | Repositório Institucional da UnB |
Download full: | http://repositorio.unb.br/handle/10482/28689 https://dx.doi.org/10.1590/0037-868212382013 |
Summary: | INTRODUCTION: Malaria caused by Plasmodium vivax species has shown signs of severity, recorded with increasing frequency in the medical literature. This study aimed to characterize the signs of severe malaria by Plasmodium vivax in the State of Maranhão, Brazil. METHODS: A descriptive cohort study of patients assisted in the field and a historical and concurrent study of a series of cases among hospitalized patients were undertaken to identify the clinical and laboratory signs of severity. RESULTS: A total of 153 patients were included in the study, 13 of whom were hospitalized. Males made up the majority, numbering 103 (67.3%). The age of the patients ranged from 10 to 70 years, 92.2% were natives of the State of Maranhão, and 65% of the patients had had malaria before. The average time elapsed between symptom onset and diagnosis among outpatients was three days, while among hospitalized patients this average reached 15.5 days, a statistically significant difference (p=0.001). The parasitemia ranged from 500 to 10,000 parasites/µl in 92.8% of cases. The clinical and laboratory manifestations of severity were vomiting and diarrhea, jaundice, drowsiness, mental confusion, seizures, loss of consciousness, agitation, bleeding, pale skin, coughing and dyspnea, thrombocytopenia, anemia, elevation of nitrogenous compounds, and elevated transaminases and bilirubin. CONCLUSIONS: The monitoring of malaria patients with Plasmodium vivax showed the possibility of aggravation, the intensity of which varied in different circumstances, especially the interval time between falling ill and diagnostic confirmation. |
id |
UNB_27c55055548cf74ffa7b4f74202ba595 |
---|---|
oai_identifier_str |
oai:repositorio2.unb.br:10482/28689 |
network_acronym_str |
UNB |
network_name_str |
Repositório Institucional da UnB |
repository_id_str |
|
spelling |
Raposo, Camila Cristina Bastos SilvaSantos, João BarberinoSantos, Gisele Maria Campelo dosGonçalves, Eloísa da Graça do RosárioSilva, Antônio Rafael da2017-12-07T05:02:24Z2017-12-07T05:02:24Z2013-02RAPOSO, Camila Cristina Bastos Silva et al. Plasmodium vivax malaria: related factors to severity in the State of Maranhão, Brazil. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 1, p. 67-72, jan./fev. 2013. DOI: https://doi.org/10.1590/0037-868212382013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000100067&lng=en&tlng=en. Acesso em: 08 set. 2020.http://repositorio.unb.br/handle/10482/28689https://dx.doi.org/10.1590/0037-868212382013Sociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical - (CC BY-NC) - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000100067&lng=en&tlng=en. Acesso em: 08 set. 2020.info:eu-repo/semantics/openAccessPlasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleMalária - BrasilGravidadePlasmodium vivaxMalária - Maranhão - epidemiologiaINTRODUCTION: Malaria caused by Plasmodium vivax species has shown signs of severity, recorded with increasing frequency in the medical literature. This study aimed to characterize the signs of severe malaria by Plasmodium vivax in the State of Maranhão, Brazil. METHODS: A descriptive cohort study of patients assisted in the field and a historical and concurrent study of a series of cases among hospitalized patients were undertaken to identify the clinical and laboratory signs of severity. RESULTS: A total of 153 patients were included in the study, 13 of whom were hospitalized. Males made up the majority, numbering 103 (67.3%). The age of the patients ranged from 10 to 70 years, 92.2% were natives of the State of Maranhão, and 65% of the patients had had malaria before. The average time elapsed between symptom onset and diagnosis among outpatients was three days, while among hospitalized patients this average reached 15.5 days, a statistically significant difference (p=0.001). The parasitemia ranged from 500 to 10,000 parasites/µl in 92.8% of cases. The clinical and laboratory manifestations of severity were vomiting and diarrhea, jaundice, drowsiness, mental confusion, seizures, loss of consciousness, agitation, bleeding, pale skin, coughing and dyspnea, thrombocytopenia, anemia, elevation of nitrogenous compounds, and elevated transaminases and bilirubin. CONCLUSIONS: The monitoring of malaria patients with Plasmodium vivax showed the possibility of aggravation, the intensity of which varied in different circumstances, especially the interval time between falling ill and diagnostic confirmation.Faculdade de Medicina (FMD)engreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNBORIGINALARTIGO_PlasmodiumVivaxMalaria.pdfARTIGO_PlasmodiumVivaxMalaria.pdfapplication/pdf342588http://repositorio2.unb.br/jspui/bitstream/10482/28689/1/ARTIGO_PlasmodiumVivaxMalaria.pdf8beb8b827ac6c4578e10b9927a7a8913MD51open access10482/286892023-08-25 15:39:04.978open accessoai:repositorio2.unb.br:10482/28689Biblioteca Digital de Teses e DissertaçõesPUBhttps://repositorio.unb.br/oai/requestopendoar:2023-08-25T18:39:04Repositório Institucional da UnB - Universidade de Brasília (UnB)false |
dc.title.pt_BR.fl_str_mv |
Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil |
title |
Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil |
spellingShingle |
Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil Raposo, Camila Cristina Bastos Silva Malária - Brasil Gravidade Plasmodium vivax Malária - Maranhão - epidemiologia |
title_short |
Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil |
title_full |
Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil |
title_fullStr |
Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil |
title_full_unstemmed |
Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil |
title_sort |
Plasmodium vivax malaria : related factors to severity in the State of Maranhão, Brazil |
author |
Raposo, Camila Cristina Bastos Silva |
author_facet |
Raposo, Camila Cristina Bastos Silva Santos, João Barberino Santos, Gisele Maria Campelo dos Gonçalves, Eloísa da Graça do Rosário Silva, Antônio Rafael da |
author_role |
author |
author2 |
Santos, João Barberino Santos, Gisele Maria Campelo dos Gonçalves, Eloísa da Graça do Rosário Silva, Antônio Rafael da |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Raposo, Camila Cristina Bastos Silva Santos, João Barberino Santos, Gisele Maria Campelo dos Gonçalves, Eloísa da Graça do Rosário Silva, Antônio Rafael da |
dc.subject.keyword.pt_BR.fl_str_mv |
Malária - Brasil Gravidade Plasmodium vivax Malária - Maranhão - epidemiologia |
topic |
Malária - Brasil Gravidade Plasmodium vivax Malária - Maranhão - epidemiologia |
description |
INTRODUCTION: Malaria caused by Plasmodium vivax species has shown signs of severity, recorded with increasing frequency in the medical literature. This study aimed to characterize the signs of severe malaria by Plasmodium vivax in the State of Maranhão, Brazil. METHODS: A descriptive cohort study of patients assisted in the field and a historical and concurrent study of a series of cases among hospitalized patients were undertaken to identify the clinical and laboratory signs of severity. RESULTS: A total of 153 patients were included in the study, 13 of whom were hospitalized. Males made up the majority, numbering 103 (67.3%). The age of the patients ranged from 10 to 70 years, 92.2% were natives of the State of Maranhão, and 65% of the patients had had malaria before. The average time elapsed between symptom onset and diagnosis among outpatients was three days, while among hospitalized patients this average reached 15.5 days, a statistically significant difference (p=0.001). The parasitemia ranged from 500 to 10,000 parasites/µl in 92.8% of cases. The clinical and laboratory manifestations of severity were vomiting and diarrhea, jaundice, drowsiness, mental confusion, seizures, loss of consciousness, agitation, bleeding, pale skin, coughing and dyspnea, thrombocytopenia, anemia, elevation of nitrogenous compounds, and elevated transaminases and bilirubin. CONCLUSIONS: The monitoring of malaria patients with Plasmodium vivax showed the possibility of aggravation, the intensity of which varied in different circumstances, especially the interval time between falling ill and diagnostic confirmation. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-02 |
dc.date.accessioned.fl_str_mv |
2017-12-07T05:02:24Z |
dc.date.available.fl_str_mv |
2017-12-07T05:02:24Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
RAPOSO, Camila Cristina Bastos Silva et al. Plasmodium vivax malaria: related factors to severity in the State of Maranhão, Brazil. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 1, p. 67-72, jan./fev. 2013. DOI: https://doi.org/10.1590/0037-868212382013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000100067&lng=en&tlng=en. Acesso em: 08 set. 2020. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unb.br/handle/10482/28689 |
dc.identifier.doi.pt_BR.fl_str_mv |
https://dx.doi.org/10.1590/0037-868212382013 |
identifier_str_mv |
RAPOSO, Camila Cristina Bastos Silva et al. Plasmodium vivax malaria: related factors to severity in the State of Maranhão, Brazil. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 1, p. 67-72, jan./fev. 2013. DOI: https://doi.org/10.1590/0037-868212382013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000100067&lng=en&tlng=en. Acesso em: 08 set. 2020. |
url |
http://repositorio.unb.br/handle/10482/28689 https://dx.doi.org/10.1590/0037-868212382013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
instname_str |
Universidade de Brasília (UnB) |
instacron_str |
UNB |
institution |
UNB |
reponame_str |
Repositório Institucional da UnB |
collection |
Repositório Institucional da UnB |
bitstream.url.fl_str_mv |
http://repositorio2.unb.br/jspui/bitstream/10482/28689/1/ARTIGO_PlasmodiumVivaxMalaria.pdf |
bitstream.checksum.fl_str_mv |
8beb8b827ac6c4578e10b9927a7a8913 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UnB - Universidade de Brasília (UnB) |
repository.mail.fl_str_mv |
|
_version_ |
1797405380392779776 |