Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review.
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Diversitas Journal |
Texto Completo: | https://diversitasjournal.com.br/diversitas_journal/article/view/2350 |
Resumo: | Azadirachta indica, popularly known as Indian neem, is an exotic plant from the Asian continent, which has great therapeutic potential. Indian neem has Azadirachtin as its main secondary metabolite, which is one of the main responsible for its therapeutic action. Currently, neem has been the subject of several researches by the pharmaceutical industry both in the field of cosmetics, medicinal uses and also in pest control. Therefore, the objective of this work was to carry out an integrative review in order to identify the antimicrobial activity of this plant. Therefore, we sought to analyze which metabolites present in the plant would contribute to the action researched in this work, as well as for which pathologies it is used according to ethnobotanical studies. In this work, articles from the main available research sources were used. The following descriptors were used to search for articles: ‘‘Azadirachta indica’’, ‘‘antibacterial’’ action, ‘‘antimicrobial’’. The time frame for searching the files corresponded to the last ten years. The data were analyzed in a qualitative way, aiming at an answer to the proposed question. The results obtained in this study show that Indian neem has a relevant antimicrobial activity and has the potential to become a therapeutic alternative in the treatment of resistant microorganisms. However, more studies should be done in order to have a better theoretical basis regarding the antimicrobial activity of the plant. |
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Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review.Atividade antimicrobiana da planta Azadirachta indica (nim indiano) – uma revisão integrativa.Azadirachta indicaNim indianoatividade antimicrobianametabólitos secundáriosAtividade antimicrobianaAzadirachta indicametabólitos secundáriosprospecção fitoquímicaNim indianoAzadirachta indica, popularly known as Indian neem, is an exotic plant from the Asian continent, which has great therapeutic potential. Indian neem has Azadirachtin as its main secondary metabolite, which is one of the main responsible for its therapeutic action. Currently, neem has been the subject of several researches by the pharmaceutical industry both in the field of cosmetics, medicinal uses and also in pest control. Therefore, the objective of this work was to carry out an integrative review in order to identify the antimicrobial activity of this plant. Therefore, we sought to analyze which metabolites present in the plant would contribute to the action researched in this work, as well as for which pathologies it is used according to ethnobotanical studies. In this work, articles from the main available research sources were used. The following descriptors were used to search for articles: ‘‘Azadirachta indica’’, ‘‘antibacterial’’ action, ‘‘antimicrobial’’. The time frame for searching the files corresponded to the last ten years. The data were analyzed in a qualitative way, aiming at an answer to the proposed question. The results obtained in this study show that Indian neem has a relevant antimicrobial activity and has the potential to become a therapeutic alternative in the treatment of resistant microorganisms. However, more studies should be done in order to have a better theoretical basis regarding the antimicrobial activity of the plant.Azadirachta indica A. Juss, conhecida comumente como Nim indiano é uma planta exótica asiática, que apresenta um grande potencial terapêutico. O Nim possui como principal metabólito secundário a Azadirachtina, sendo esse um dos principais responsáveis pela sua ação terapêutica. Atualmente o Nim vem sendo alvo de diversas pesquisas pela indústria farmacêutica tanto no âmbito de cosméticos, usos medicinais e também no controle de pragas. Diante disso, o objetivo deste trabalho foi realizar uma revisão integrativa, a fim de apresentar dados da literatura acerca a atividade antimicrobiana desta planta, frente a bactérias, fungos e vírus. Neste trabalho utilizou-se artigos oriundos das bases de dados como SciELO, LILACS, MEDLINE, Biblioteca Virtual em Saúde (BVS) e no buscador acadêmico Google Scholar. Foram utilizados na busca os seguintes descritores: ‘‘Azadirachta indica’’, ‘‘atividade antimicrobiana’’, ‘‘resistência microbiana’’, ‘‘fitoterapia’’. O recorte temporal correspondera aos anos de 2012 a 2022, nos idiomas português e inglês. Os critérios de inclusão adotados foram: trabalhos que apresentaram todos os descritores referentes ao tema da pesquisa, escritos em português e inglês, trabalhos que puderam ser analisados na íntegra, como artigos completos de acesso gratuito, artigos de pesquisa, artigos de revisão, teses, dissertações e trabalhos de conclusão de curso. Os critérios de exclusão englobaram livros, artigos que não apresentaram os descritores da pesquisa, publicados antes do ano de 2012, artigos de acesso pago, trabalhos duplicados, que fugiram do tema discutido, que apresentavam textos incompletos e metodologias inconsistentes. Dos 1034 trabalhos analisados, foram incluídos 24 trabalhos no estudo. Os dados foram analisados de maneira qualitativa, visando uma resposta para o questionamento proposto. Os resultados obtidos nesse estudo mostram que o Nim indiano apresenta uma atividade antimicrobiana relevante frente a fungos, vírus e principalmente bactérias, evidenciando-se como uma alternativa terapêutica no tratamento de microrganismos resistentes. Entretanto, é necessário que mais estudos frente aos patógenos que foram menos relatados aqui sejam realizados, bem como ensaios de caracterização química e citotoxicidade desse vegetal, para que este seja usado de forma segura e se tenha um maior embasamento teórico a respeito da atividade antimicrobiana da planta.Universidade Estadual de Alagoas - Eduneal2022-10-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://diversitasjournal.com.br/diversitas_journal/article/view/235010.48017/dj.v7i4.2350Diversitas Journal; v. 7 n. 4 (2022): A força do associativismo é sempre alternativa para o desenvolvimento2525-521510.48017/dj.v7i4reponame:Diversitas Journalinstname:Universidade Estadual de Alagoas (UNEAL)instacron:UNEALporhttps://diversitasjournal.com.br/diversitas_journal/article/view/2350/1776Copyright (c) 2022 Elon, Cândida, Luanne, Ítalo Diegohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGuedes, Elon MeloMendonça, Cândida Maria Soares de Nunes, Luanne Eugênia Araújo, Ítalo Diego Rebouças de2022-10-10T03:23:17Zoai:ojs.emnuvens.com.br:article/2350Revistahttps://diversitasjournal.com.br/diversitas_journal/indexPUBhttps://www.e-publicacoes.uerj.br/index.php/muralinternacional/oairevistadiversitasjournal@gmail.com2525-52152525-5215opendoar:2023-01-13T09:47:36.985888Diversitas Journal - Universidade Estadual de Alagoas (UNEAL)false |
dc.title.none.fl_str_mv |
Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review. Atividade antimicrobiana da planta Azadirachta indica (nim indiano) – uma revisão integrativa. |
title |
Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review. |
spellingShingle |
Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review. Guedes, Elon Melo Azadirachta indica Nim indiano atividade antimicrobiana metabólitos secundários Atividade antimicrobiana Azadirachta indica metabólitos secundários prospecção fitoquímica Nim indiano |
title_short |
Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review. |
title_full |
Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review. |
title_fullStr |
Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review. |
title_full_unstemmed |
Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review. |
title_sort |
Antimicrobial activity of the plant Azadirachta indica (indian nim) – an integrative review. |
author |
Guedes, Elon Melo |
author_facet |
Guedes, Elon Melo Mendonça, Cândida Maria Soares de Nunes, Luanne Eugênia Araújo, Ítalo Diego Rebouças de |
author_role |
author |
author2 |
Mendonça, Cândida Maria Soares de Nunes, Luanne Eugênia Araújo, Ítalo Diego Rebouças de |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Guedes, Elon Melo Mendonça, Cândida Maria Soares de Nunes, Luanne Eugênia Araújo, Ítalo Diego Rebouças de |
dc.subject.por.fl_str_mv |
Azadirachta indica Nim indiano atividade antimicrobiana metabólitos secundários Atividade antimicrobiana Azadirachta indica metabólitos secundários prospecção fitoquímica Nim indiano |
topic |
Azadirachta indica Nim indiano atividade antimicrobiana metabólitos secundários Atividade antimicrobiana Azadirachta indica metabólitos secundários prospecção fitoquímica Nim indiano |
description |
Azadirachta indica, popularly known as Indian neem, is an exotic plant from the Asian continent, which has great therapeutic potential. Indian neem has Azadirachtin as its main secondary metabolite, which is one of the main responsible for its therapeutic action. Currently, neem has been the subject of several researches by the pharmaceutical industry both in the field of cosmetics, medicinal uses and also in pest control. Therefore, the objective of this work was to carry out an integrative review in order to identify the antimicrobial activity of this plant. Therefore, we sought to analyze which metabolites present in the plant would contribute to the action researched in this work, as well as for which pathologies it is used according to ethnobotanical studies. In this work, articles from the main available research sources were used. The following descriptors were used to search for articles: ‘‘Azadirachta indica’’, ‘‘antibacterial’’ action, ‘‘antimicrobial’’. The time frame for searching the files corresponded to the last ten years. The data were analyzed in a qualitative way, aiming at an answer to the proposed question. The results obtained in this study show that Indian neem has a relevant antimicrobial activity and has the potential to become a therapeutic alternative in the treatment of resistant microorganisms. However, more studies should be done in order to have a better theoretical basis regarding the antimicrobial activity of the plant. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-10-10 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://diversitasjournal.com.br/diversitas_journal/article/view/2350 10.48017/dj.v7i4.2350 |
url |
https://diversitasjournal.com.br/diversitas_journal/article/view/2350 |
identifier_str_mv |
10.48017/dj.v7i4.2350 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://diversitasjournal.com.br/diversitas_journal/article/view/2350/1776 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Elon, Cândida, Luanne, Ítalo Diego https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Elon, Cândida, Luanne, Ítalo Diego https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual de Alagoas - Eduneal |
publisher.none.fl_str_mv |
Universidade Estadual de Alagoas - Eduneal |
dc.source.none.fl_str_mv |
Diversitas Journal; v. 7 n. 4 (2022): A força do associativismo é sempre alternativa para o desenvolvimento 2525-5215 10.48017/dj.v7i4 reponame:Diversitas Journal instname:Universidade Estadual de Alagoas (UNEAL) instacron:UNEAL |
instname_str |
Universidade Estadual de Alagoas (UNEAL) |
instacron_str |
UNEAL |
institution |
UNEAL |
reponame_str |
Diversitas Journal |
collection |
Diversitas Journal |
repository.name.fl_str_mv |
Diversitas Journal - Universidade Estadual de Alagoas (UNEAL) |
repository.mail.fl_str_mv |
revistadiversitasjournal@gmail.com |
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1797051274537992192 |