Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Dental Science |
Texto Completo: | https://ojs.ict.unesp.br/index.php/cob/article/view/1044 |
Resumo: | Objective: Oral candidiasis is the most common fungal infection of the oral cavity, and Candida albicans is the most frequently isolated species. Material and Methods: In this study, the potential antifungal effect of extracts from Gossypium hirsutum L., Arctium lappa, Equisetum sp., Cecropia pachystachya Trécul and Pogostemon heyneanus plants were evaluated on non-adhered cells of C. albicans, and the effect of oral antiseptics A (cetylpyridinium chloride 0.500 mg), B (chlorhexidine gluconate 0.12%), C (hydrogen peroxide 1.5%) and D (thymol, eucalyptol, menthol and methyl salicylate) were evaluated on non-adhered cells and biofilms of C. albicans, using turbidimetry and minimal inhibitory concentration (MIC) of the extracts and the maximal inhibitory dilution (MID) of the antiseptics. Results: The most promising results on non-adhered cells were obtained with Cecropia pachystachyaTrécul extracts, with MIC values between 7.81 and 3.91 µg/mL. Antiseptics A and B showed the lowest MID values, between 0.20 and 0.10% (Kruskal-Wallis, p<0.0001). Regarding biofilm inhibition, the MID values found were similar for the tested antiseptics, varying from 50% to 0.20% (Kruskal-Wallis, p=0.6915). Conclusion: These results show that some plant extracts has potential use in the prevention and treatment of oral candidiasis. |
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Brazilian Dental Science |
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Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicansObjective: Oral candidiasis is the most common fungal infection of the oral cavity, and Candida albicans is the most frequently isolated species. Material and Methods: In this study, the potential antifungal effect of extracts from Gossypium hirsutum L., Arctium lappa, Equisetum sp., Cecropia pachystachya Trécul and Pogostemon heyneanus plants were evaluated on non-adhered cells of C. albicans, and the effect of oral antiseptics A (cetylpyridinium chloride 0.500 mg), B (chlorhexidine gluconate 0.12%), C (hydrogen peroxide 1.5%) and D (thymol, eucalyptol, menthol and methyl salicylate) were evaluated on non-adhered cells and biofilms of C. albicans, using turbidimetry and minimal inhibitory concentration (MIC) of the extracts and the maximal inhibitory dilution (MID) of the antiseptics. Results: The most promising results on non-adhered cells were obtained with Cecropia pachystachyaTrécul extracts, with MIC values between 7.81 and 3.91 µg/mL. Antiseptics A and B showed the lowest MID values, between 0.20 and 0.10% (Kruskal-Wallis, p<0.0001). Regarding biofilm inhibition, the MID values found were similar for the tested antiseptics, varying from 50% to 0.20% (Kruskal-Wallis, p=0.6915). Conclusion: These results show that some plant extracts has potential use in the prevention and treatment of oral candidiasis. Institute of Science and Technology of São José dos Campos2014-11-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/mswordapplication/mswordimage/jpegimage/tiffimage/tiffimage/tiffimage/tiffhttps://ojs.ict.unesp.br/index.php/cob/article/view/104410.14295/bds.2014.v17i4.1044Brazilian Dental Science; Vol. 17 No. 4 (2014): Oct. - Dec. / 2014 - Published November 2014; 98-105Brazilian Dental Science; v. 17 n. 4 (2014): Oct. - Dec. / 2014 - Published November 2014; 98-1052178-6011reponame:Brazilian Dental Scienceinstname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)instacron:UNESPenghttps://ojs.ict.unesp.br/index.php/cob/article/view/1044/904https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2169https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2170https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2171https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2172https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2173https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2174https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2175Balliana, Roberta Carvalho SthelJamal, Cláudia MasrouahMaifrede, Simone BravimAraújo, Mariceli Lamas deinfo:eu-repo/semantics/openAccess2020-01-28T12:30:28Zoai:ojs.pkp.sfu.ca:article/1044Revistahttp://bds.ict.unesp.br/PUBhttp://ojs.fosjc.unesp.br/index.php/index/oaisergio@fosjc.unesp.br||sergio@fosjc.unesp.br2178-60112178-6011opendoar:2022-11-08T16:29:58.824167Brazilian Dental Science - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)true |
dc.title.none.fl_str_mv |
Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans |
title |
Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans |
spellingShingle |
Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans Balliana, Roberta Carvalho Sthel |
title_short |
Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans |
title_full |
Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans |
title_fullStr |
Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans |
title_full_unstemmed |
Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans |
title_sort |
Evaluation of the antifungal activity of plant extracts and oral antiseptics against Candida albicans |
author |
Balliana, Roberta Carvalho Sthel |
author_facet |
Balliana, Roberta Carvalho Sthel Jamal, Cláudia Masrouah Maifrede, Simone Bravim Araújo, Mariceli Lamas de |
author_role |
author |
author2 |
Jamal, Cláudia Masrouah Maifrede, Simone Bravim Araújo, Mariceli Lamas de |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Balliana, Roberta Carvalho Sthel Jamal, Cláudia Masrouah Maifrede, Simone Bravim Araújo, Mariceli Lamas de |
description |
Objective: Oral candidiasis is the most common fungal infection of the oral cavity, and Candida albicans is the most frequently isolated species. Material and Methods: In this study, the potential antifungal effect of extracts from Gossypium hirsutum L., Arctium lappa, Equisetum sp., Cecropia pachystachya Trécul and Pogostemon heyneanus plants were evaluated on non-adhered cells of C. albicans, and the effect of oral antiseptics A (cetylpyridinium chloride 0.500 mg), B (chlorhexidine gluconate 0.12%), C (hydrogen peroxide 1.5%) and D (thymol, eucalyptol, menthol and methyl salicylate) were evaluated on non-adhered cells and biofilms of C. albicans, using turbidimetry and minimal inhibitory concentration (MIC) of the extracts and the maximal inhibitory dilution (MID) of the antiseptics. Results: The most promising results on non-adhered cells were obtained with Cecropia pachystachyaTrécul extracts, with MIC values between 7.81 and 3.91 µg/mL. Antiseptics A and B showed the lowest MID values, between 0.20 and 0.10% (Kruskal-Wallis, p<0.0001). Regarding biofilm inhibition, the MID values found were similar for the tested antiseptics, varying from 50% to 0.20% (Kruskal-Wallis, p=0.6915). Conclusion: These results show that some plant extracts has potential use in the prevention and treatment of oral candidiasis. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-11-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.ict.unesp.br/index.php/cob/article/view/1044 10.14295/bds.2014.v17i4.1044 |
url |
https://ojs.ict.unesp.br/index.php/cob/article/view/1044 |
identifier_str_mv |
10.14295/bds.2014.v17i4.1044 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.ict.unesp.br/index.php/cob/article/view/1044/904 https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2169 https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2170 https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2171 https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2172 https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2173 https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2174 https://ojs.ict.unesp.br/index.php/cob/article/view/1044/2175 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/msword application/msword image/jpeg image/tiff image/tiff image/tiff image/tiff |
dc.publisher.none.fl_str_mv |
Institute of Science and Technology of São José dos Campos |
publisher.none.fl_str_mv |
Institute of Science and Technology of São José dos Campos |
dc.source.none.fl_str_mv |
Brazilian Dental Science; Vol. 17 No. 4 (2014): Oct. - Dec. / 2014 - Published November 2014; 98-105 Brazilian Dental Science; v. 17 n. 4 (2014): Oct. - Dec. / 2014 - Published November 2014; 98-105 2178-6011 reponame:Brazilian Dental Science instname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Brazilian Dental Science |
collection |
Brazilian Dental Science |
repository.name.fl_str_mv |
Brazilian Dental Science - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
repository.mail.fl_str_mv |
sergio@fosjc.unesp.br||sergio@fosjc.unesp.br |
_version_ |
1788346899012517888 |