Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Dental Science |
Texto Completo: | https://ojs.ict.unesp.br/index.php/cob/article/view/1739 |
Resumo: | Objective: Evaluate and compare the antimicrobial efficacy of four different commercially available children’s toothpastes on bacteria growth inhibition from oral microbiota of young children. Material and Method: The toothpastes tested contained: 1100 ppm sodium fluoride, xylitol and 750 ppm sodium fluoride, xylitol and 500 ppm sodium fluoride, and xylitol and triclosan. Twenty 18 to 30 month-old children were selected. Nonstimulated saliva samples were collected and inoculated on brain heart infusion (BHI) agar. Toothpaste dilutions were applied into the agar wells and incubated at 37ºC for 24 hours in microaerophilic conditions. Saline and 0.12% chlorhexidine were used as controls. Antimicrobial activity was determined in duplicate by agar-well diffusion technique. Bacterial growth inhibition zones were recorded in mm. Statistical analysis was performed using ANOVA and Tukey's test (p<0.05). Results: All toothpastes showed antimicrobial activity when compared to negative control (p<0.05). Toothpaste containing triclosan presented the highest antimicrobial activity followed, in this order, by xylitol and 750 ppm sodium fluoride, chlorhexidine, 1100 ppm sodium fluoride, xylitol and 500 ppm sodium fluoride and saline. Conclusions: Toothpaste containing triclosan and xylitol presented excellent antimicrobial activity, and may be considered a good option for young children.Key words: Toothpastes. Oral hygiene. Pediatric Dentistry. |
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oai:ojs.pkp.sfu.ca:article/1739 |
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UNESP-20 |
network_name_str |
Brazilian Dental Science |
repository_id_str |
|
spelling |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and XylitolObjective: Evaluate and compare the antimicrobial efficacy of four different commercially available children’s toothpastes on bacteria growth inhibition from oral microbiota of young children. Material and Method: The toothpastes tested contained: 1100 ppm sodium fluoride, xylitol and 750 ppm sodium fluoride, xylitol and 500 ppm sodium fluoride, and xylitol and triclosan. Twenty 18 to 30 month-old children were selected. Nonstimulated saliva samples were collected and inoculated on brain heart infusion (BHI) agar. Toothpaste dilutions were applied into the agar wells and incubated at 37ºC for 24 hours in microaerophilic conditions. Saline and 0.12% chlorhexidine were used as controls. Antimicrobial activity was determined in duplicate by agar-well diffusion technique. Bacterial growth inhibition zones were recorded in mm. Statistical analysis was performed using ANOVA and Tukey's test (p<0.05). Results: All toothpastes showed antimicrobial activity when compared to negative control (p<0.05). Toothpaste containing triclosan presented the highest antimicrobial activity followed, in this order, by xylitol and 750 ppm sodium fluoride, chlorhexidine, 1100 ppm sodium fluoride, xylitol and 500 ppm sodium fluoride and saline. Conclusions: Toothpaste containing triclosan and xylitol presented excellent antimicrobial activity, and may be considered a good option for young children.Key words: Toothpastes. Oral hygiene. Pediatric Dentistry. Institute of Science and Technology of São José dos Campos2019-07-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/mswordapplication/mswordapplication/mswordapplication/mswordhttps://ojs.ict.unesp.br/index.php/cob/article/view/173910.14295/bds.2019.v22i3.1739Brazilian Dental Science; Vol. 22 No. 3 (2019): Jul. - Sep. / 2019 - Published July 2019; 344-348Brazilian Dental Science; v. 22 n. 3 (2019): Jul. - Sep. / 2019 - Published July 2019; 344-3482178-6011reponame:Brazilian Dental Scienceinstname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)instacron:UNESPenghttps://ojs.ict.unesp.br/index.php/cob/article/view/1739/1378https://ojs.ict.unesp.br/index.php/cob/article/view/1739/3655https://ojs.ict.unesp.br/index.php/cob/article/view/1739/3656https://ojs.ict.unesp.br/index.php/cob/article/view/1739/3657https://ojs.ict.unesp.br/index.php/cob/article/view/1739/3771Copyright (c) 2019 Brazilian Dental Scienceinfo:eu-repo/semantics/openAccessCosme-Silva, Leopoldoda Silveira, Ana Paula PereiraGasque, Kellen Cristina da SilvaMoretti Neto, Rafael TobiasSakai, Vivien ThiemyMoretti, Ana Beatriz S2020-01-28T12:01:15Zoai:ojs.pkp.sfu.ca:article/1739Revistahttp://bds.ict.unesp.br/PUBhttp://ojs.fosjc.unesp.br/index.php/index/oaisergio@fosjc.unesp.br||sergio@fosjc.unesp.br2178-60112178-6011opendoar:2022-11-08T16:30:22.203042Brazilian Dental Science - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)true |
dc.title.none.fl_str_mv |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol |
title |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol |
spellingShingle |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol Cosme-Silva, Leopoldo |
title_short |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol |
title_full |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol |
title_fullStr |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol |
title_full_unstemmed |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol |
title_sort |
Antimicrobial activity of various brands of children's toothpastes formulated with Triclosan, Fluoride and Xylitol |
author |
Cosme-Silva, Leopoldo |
author_facet |
Cosme-Silva, Leopoldo da Silveira, Ana Paula Pereira Gasque, Kellen Cristina da Silva Moretti Neto, Rafael Tobias Sakai, Vivien Thiemy Moretti, Ana Beatriz S |
author_role |
author |
author2 |
da Silveira, Ana Paula Pereira Gasque, Kellen Cristina da Silva Moretti Neto, Rafael Tobias Sakai, Vivien Thiemy Moretti, Ana Beatriz S |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Cosme-Silva, Leopoldo da Silveira, Ana Paula Pereira Gasque, Kellen Cristina da Silva Moretti Neto, Rafael Tobias Sakai, Vivien Thiemy Moretti, Ana Beatriz S |
description |
Objective: Evaluate and compare the antimicrobial efficacy of four different commercially available children’s toothpastes on bacteria growth inhibition from oral microbiota of young children. Material and Method: The toothpastes tested contained: 1100 ppm sodium fluoride, xylitol and 750 ppm sodium fluoride, xylitol and 500 ppm sodium fluoride, and xylitol and triclosan. Twenty 18 to 30 month-old children were selected. Nonstimulated saliva samples were collected and inoculated on brain heart infusion (BHI) agar. Toothpaste dilutions were applied into the agar wells and incubated at 37ºC for 24 hours in microaerophilic conditions. Saline and 0.12% chlorhexidine were used as controls. Antimicrobial activity was determined in duplicate by agar-well diffusion technique. Bacterial growth inhibition zones were recorded in mm. Statistical analysis was performed using ANOVA and Tukey's test (p<0.05). Results: All toothpastes showed antimicrobial activity when compared to negative control (p<0.05). Toothpaste containing triclosan presented the highest antimicrobial activity followed, in this order, by xylitol and 750 ppm sodium fluoride, chlorhexidine, 1100 ppm sodium fluoride, xylitol and 500 ppm sodium fluoride and saline. Conclusions: Toothpaste containing triclosan and xylitol presented excellent antimicrobial activity, and may be considered a good option for young children.Key words: Toothpastes. Oral hygiene. Pediatric Dentistry. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-07-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.ict.unesp.br/index.php/cob/article/view/1739 10.14295/bds.2019.v22i3.1739 |
url |
https://ojs.ict.unesp.br/index.php/cob/article/view/1739 |
identifier_str_mv |
10.14295/bds.2019.v22i3.1739 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.ict.unesp.br/index.php/cob/article/view/1739/1378 https://ojs.ict.unesp.br/index.php/cob/article/view/1739/3655 https://ojs.ict.unesp.br/index.php/cob/article/view/1739/3656 https://ojs.ict.unesp.br/index.php/cob/article/view/1739/3657 https://ojs.ict.unesp.br/index.php/cob/article/view/1739/3771 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2019 Brazilian Dental Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2019 Brazilian Dental Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/msword application/msword application/msword application/msword |
dc.publisher.none.fl_str_mv |
Institute of Science and Technology of São José dos Campos |
publisher.none.fl_str_mv |
Institute of Science and Technology of São José dos Campos |
dc.source.none.fl_str_mv |
Brazilian Dental Science; Vol. 22 No. 3 (2019): Jul. - Sep. / 2019 - Published July 2019; 344-348 Brazilian Dental Science; v. 22 n. 3 (2019): Jul. - Sep. / 2019 - Published July 2019; 344-348 2178-6011 reponame:Brazilian Dental Science instname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Brazilian Dental Science |
collection |
Brazilian Dental Science |
repository.name.fl_str_mv |
Brazilian Dental Science - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
repository.mail.fl_str_mv |
sergio@fosjc.unesp.br||sergio@fosjc.unesp.br |
_version_ |
1788346900818165760 |