Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review

Detalhes bibliográficos
Autor(a) principal: Lucena, Virgínia Raquel dos Santos
Data de Publicação: 2021
Outros Autores: Araújo, Rícia Medeiros Palmeira de, Medeiros, Deborah Laís Nóbrega de, Silva, Maria Fernanda Almeida, Neto, Sebastião Duque
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/16087
Resumo: Introduction: The influence of biological rhythmicity on the regulation of several systems, including the gastrointestinal system, is well known. In this context, several recent studies relate the release of melatonin, as an important substance in the healing of ulcerative lesions in the gastrointestinal tract. Objective: To investigate studies and evidence about the role of melatonin as a complementary treatment for gastroduodenal ulcers and its relationship with chronobiology. Methodology: This is an integrative review study, carried out through an active search in the Scientific Eletronic Library Online (SciELO), PubMed, Science Direct and Latin American and Caribbean Literature in Health Sciences (LILACS) databases in August 2020. Results: In several of the studies analyzed, the administration of melatonin proved to be effective and safe to accelerate the rate of healing of gastroduodenal ulcers of different etiologies due to its antioxidant and anti-inflammatory activities. Conclusion: Although there is innumerable evidence, the literature is still scarce regarding the treatment or pre-treatment of ulcers with melatonin, either alone or in conjunction with other drugs.
id UNIFEI_087f7661317f070e5920e89fa56fecda
oai_identifier_str oai:ojs.pkp.sfu.ca:article/16087
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative reviewEfectos de la melatonina como tratamiento complementario de las úlceras gastroduodenales: Una revisión integradoraEfeitos da melatonina como tratamento complementar de úlceras gastroduodenais: Uma revisão integrativaChronobiologyMelatoninGastroduodenal ulcers.CronobiologíaMelatoninaÚlceras gastroduodenales.CronobiologiaMelatoninaÚlceras gastroduodenais.Introduction: The influence of biological rhythmicity on the regulation of several systems, including the gastrointestinal system, is well known. In this context, several recent studies relate the release of melatonin, as an important substance in the healing of ulcerative lesions in the gastrointestinal tract. Objective: To investigate studies and evidence about the role of melatonin as a complementary treatment for gastroduodenal ulcers and its relationship with chronobiology. Methodology: This is an integrative review study, carried out through an active search in the Scientific Eletronic Library Online (SciELO), PubMed, Science Direct and Latin American and Caribbean Literature in Health Sciences (LILACS) databases in August 2020. Results: In several of the studies analyzed, the administration of melatonin proved to be effective and safe to accelerate the rate of healing of gastroduodenal ulcers of different etiologies due to its antioxidant and anti-inflammatory activities. Conclusion: Although there is innumerable evidence, the literature is still scarce regarding the treatment or pre-treatment of ulcers with melatonin, either alone or in conjunction with other drugs.Introducción: Es bien conocida la influencia de la ritmicidad biológica en la regulación de varios sistemas, incluido el gastrointestinal. En este contexto, varios estudios recientes relacionan la liberación de melatonina, como una sustancia importante en la cicatrización de lesiones ulcerativas en el tracto gastrointestinal. Objetivo: investigar estudios y evidencias sobre el papel de la melatonina como tratamiento complementario de las úlceras gastroduodenales y su relación con la cronobiología. Metodología: Se trata de un estudio de revisión integradora, realizado a través de una búsqueda activa en las bases de datos Scientific Eletronic Library Online (SciELO), PubMed, Science Direct y Latin American and Caribbean Literature in Health Sciences (LILACS) en agosto de 2020. Resultados: En varios De los estudios analizados, la administración de melatonina demostró ser eficaz y segura para acelerar la tasa de curación de úlceras gastroduodenales de diferentes etiologías debido a sus actividades antioxidantes y antiinflamatorias. Conclusión: Aunque existe una innumerable evidencia, la literatura aún es escasa sobre el tratamiento o pretratamiento de las úlceras con melatonina, ya sea sola o en conjunto con otros fármacos.Introdução: É conhecida a influência da ritmicidade biológica na regulação de diversos sistemas, incluindo o gastrointestinal. Nesse contexto, vários estudos recentes relacionam a liberação de melatonina, como uma substância importante na cicatrização de lesões ulcerativas no trato gastrointestinal. Objetivo: Investigar estudos e evidências acerca do papel da melatonina como tratamento complementar de úlceras gastroduodenais e sua relação com a cronobiologia. Metodologia: Trata-se de um estudo de revisão integrativa, realizada por meio de busca ativa nas bases de dados Scientific Eletronic Library Online (SciELO), PubMed, Science Direct e Literatura Latino Americana e do Caribe em Ciências da Saúde (LILACS) em agosto de 2020. Resultados: Em vários dos estudos analisados, a administração de melatonina mostrou-se eficaz e segura para acelerar a taxa de cicatrização das úlceras gastroduodenais de distintas etiologias por suas atividades antioxidante e anti-inflamatórias. Conclusão: Embora existam inúmeras evidências, a literatura é a ainda escassa quanto à realização do tratamento ou pré-tratamento das úlceras com melatonina, seja isoladamente ou em conjunto com outras drogas.Research, Society and Development2021-06-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1608710.33448/rsd-v10i6.16087Research, Society and Development; Vol. 10 No. 6; e52310616087Research, Society and Development; Vol. 10 Núm. 6; e52310616087Research, Society and Development; v. 10 n. 6; e523106160872525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/16087/14371Copyright (c) 2021 Virgínia Raquel dos Santos Lucena; Rícia Medeiros Palmeira de Araújo; Deborah Laís Nóbrega de Medeiros; Maria Fernanda Almeida Silva; Sebastião Duque Netohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLucena, Virgínia Raquel dos SantosAraújo, Rícia Medeiros Palmeira de Medeiros, Deborah Laís Nóbrega deSilva, Maria Fernanda Almeida Neto, Sebastião Duque2021-06-10T22:51:46Zoai:ojs.pkp.sfu.ca:article/16087Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:36:44.689139Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review
Efectos de la melatonina como tratamiento complementario de las úlceras gastroduodenales: Una revisión integradora
Efeitos da melatonina como tratamento complementar de úlceras gastroduodenais: Uma revisão integrativa
title Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review
spellingShingle Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review
Lucena, Virgínia Raquel dos Santos
Chronobiology
Melatonin
Gastroduodenal ulcers.
Cronobiología
Melatonina
Úlceras gastroduodenales.
Cronobiologia
Melatonina
Úlceras gastroduodenais.
title_short Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review
title_full Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review
title_fullStr Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review
title_full_unstemmed Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review
title_sort Effects of melatonin as a complementary treatment for gastroduodenal ulcers: An integrative review
author Lucena, Virgínia Raquel dos Santos
author_facet Lucena, Virgínia Raquel dos Santos
Araújo, Rícia Medeiros Palmeira de
Medeiros, Deborah Laís Nóbrega de
Silva, Maria Fernanda Almeida
Neto, Sebastião Duque
author_role author
author2 Araújo, Rícia Medeiros Palmeira de
Medeiros, Deborah Laís Nóbrega de
Silva, Maria Fernanda Almeida
Neto, Sebastião Duque
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lucena, Virgínia Raquel dos Santos
Araújo, Rícia Medeiros Palmeira de
Medeiros, Deborah Laís Nóbrega de
Silva, Maria Fernanda Almeida
Neto, Sebastião Duque
dc.subject.por.fl_str_mv Chronobiology
Melatonin
Gastroduodenal ulcers.
Cronobiología
Melatonina
Úlceras gastroduodenales.
Cronobiologia
Melatonina
Úlceras gastroduodenais.
topic Chronobiology
Melatonin
Gastroduodenal ulcers.
Cronobiología
Melatonina
Úlceras gastroduodenales.
Cronobiologia
Melatonina
Úlceras gastroduodenais.
description Introduction: The influence of biological rhythmicity on the regulation of several systems, including the gastrointestinal system, is well known. In this context, several recent studies relate the release of melatonin, as an important substance in the healing of ulcerative lesions in the gastrointestinal tract. Objective: To investigate studies and evidence about the role of melatonin as a complementary treatment for gastroduodenal ulcers and its relationship with chronobiology. Methodology: This is an integrative review study, carried out through an active search in the Scientific Eletronic Library Online (SciELO), PubMed, Science Direct and Latin American and Caribbean Literature in Health Sciences (LILACS) databases in August 2020. Results: In several of the studies analyzed, the administration of melatonin proved to be effective and safe to accelerate the rate of healing of gastroduodenal ulcers of different etiologies due to its antioxidant and anti-inflammatory activities. Conclusion: Although there is innumerable evidence, the literature is still scarce regarding the treatment or pre-treatment of ulcers with melatonin, either alone or in conjunction with other drugs.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-08
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/16087
10.33448/rsd-v10i6.16087
url https://rsdjournal.org/index.php/rsd/article/view/16087
identifier_str_mv 10.33448/rsd-v10i6.16087
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/16087/14371
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 6; e52310616087
Research, Society and Development; Vol. 10 Núm. 6; e52310616087
Research, Society and Development; v. 10 n. 6; e52310616087
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052786135793664

Registros relacionados