Single Crystal of 1-(2'-hidroxyphenyl)-3-hidroxy-3-(4-methoxyphenil)-propan-1-one: Synthesis, structure and vibrational properties

• Autor(a) principal: Bitencourt , Heriberto Rodrigues
• Data de Publicação: 2022
• Outros Autores: Pinheiro, José Ciriaco, Souza Filho, Antônio Pedro da Silva, Moreira, Sanclayton Geraldo, Ayala, Alejandro Pedro, Remédios, Cláudio Márcio Rocha
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/31433
• topic: Derivados de chalconas; Síntese de flavonóides; Estrutura de flavonóides; Raman em flavonóides.; Derivados de chalconas; Síntesis de flavonoides; Estructura de flavonoides; Raman en flavonoides.; Chalcones derivatives; Flavonoid synthesis; Flavonoids structure; Raman in flavonoids.

Chalcones, flavonoids, isoflavonoids and other derived substances have been extensively studied in recent years presenting various pharmacological activities and in some cases presenting very important physical properties such as non-linear optical properties (ONL). Recently it was observed that the compound 1-(2'-hydroxyphenyl)-3-hydroxy-3-(4-methoxyphenyl)-propan-1-one is an intermediate precursor in the biosynthesis of (2E)-1-(2-hydroxyphenyl) -3-(4-methoxyphenyl)prop-2-en-1-one, which is a compound belonging to the class of chalcones. After this observation, said precursor compound was crystallized in the laboratory and its crystal structure was identified by X-ray diffraction. The title compound was synthesized and crystallized from methanol in the centrosymmetric space group P21/c. The geometric parameters and supramolecular arrangement of the crystal structure obtained from single crystal X-ray diffraction data were analyzed. Furthermore, the vibrational properties were characterized by Raman spectroscopy. The attributions of the vibrational modes and detailed information of the synthesis are presented.