Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region

Detalhes bibliográficos
Autor(a) principal: Oliveira, July Martins de
Data de Publicação: 2021
Outros Autores: Valle, Ian Mazzetti Rodrigues, Naue, Carine Rosa, Santos, Itamar, Lima, Ricardo Santana de, Guimarães, Marcos Duarte
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/23691
Resumo: Severe Acute Respiratory Syndromes (SARS) can be defined by the presence of fever, cough (or sore throat) and dyspnoea, or reduction in O2 saturation. Although they have many etiologies, during the 2020 pandemic occurred a significant increase in the reported cases resulting from infections by SARS-CoV-2. The present study aims to describe the clinical, epidemiological and laboratory data of patients admitted to the University Hospital of the Federal University of Vale do São Francisco with suspected SARS due to COVID-19 or unspecified. This is a retrospective, observational cross-sectional study, with a sample of 72 individuals, admitted between March and July 2020. Data were collected from electronic medical records. For data analysis, simple and relative frequencies were calculated and statistical analysis were performed using SPSS. Most individuals were male and had an average age of approximately 57 years. Regarding comorbidity 86.11% had at least one. The most prevalent being hypertension, advanced age and metabolic disorders. Fever, reduced O2 saturation and dyspnoea were the most common symptoms among the 47 patients infected with SARS-CoV-2. High levels of TGO, D-dimer and ferritin, as well as a reduction in the rates of albumin and hemoglobin were the most common laboratory alterations. Furthermore, 74.5% required mechanical ventilation, and the major outcome was death. The data described are able to help clinical practice, as they show the most frequent findings observed in individuals with SARS.
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spelling Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle regionPerfil clínico, epidemiológico y de laboratorio de pacientes con Síndromes Respiratorios Agudos Graves (SRAG) y COVID-19, ingresados en un Hospital Universitario de la Región del submédio del São FranciscoPerfil clínico, epidemiológico e laboratorial de pacientes portadores de Síndromes Respiratórias Agudas Graves (SRAGs) e COVID-19, admitidos em um Hospital Universitário da região do submédio do São Francisco COVID-19Síndrome Respiratória Aguda GraveSinais e sintomas.COVID-19Síndrome Respiratorio Agudo GraveSignos y síntomas.COVID-19Severe Acute Respiratory SyndromeSigns and symptoms.Severe Acute Respiratory Syndromes (SARS) can be defined by the presence of fever, cough (or sore throat) and dyspnoea, or reduction in O2 saturation. Although they have many etiologies, during the 2020 pandemic occurred a significant increase in the reported cases resulting from infections by SARS-CoV-2. The present study aims to describe the clinical, epidemiological and laboratory data of patients admitted to the University Hospital of the Federal University of Vale do São Francisco with suspected SARS due to COVID-19 or unspecified. This is a retrospective, observational cross-sectional study, with a sample of 72 individuals, admitted between March and July 2020. Data were collected from electronic medical records. For data analysis, simple and relative frequencies were calculated and statistical analysis were performed using SPSS. Most individuals were male and had an average age of approximately 57 years. Regarding comorbidity 86.11% had at least one. The most prevalent being hypertension, advanced age and metabolic disorders. Fever, reduced O2 saturation and dyspnoea were the most common symptoms among the 47 patients infected with SARS-CoV-2. High levels of TGO, D-dimer and ferritin, as well as a reduction in the rates of albumin and hemoglobin were the most common laboratory alterations. Furthermore, 74.5% required mechanical ventilation, and the major outcome was death. The data described are able to help clinical practice, as they show the most frequent findings observed in individuals with SARS.Los síndromes respiratorios agudos graves (SRAG) pueden definirse por la presencia de fiebre, tos (o dolor de garganta) y disnea, o reducción de la saturación de O2. Aunque tienen etiologías variadas, la pandemia de 2020 provocó un aumento significativo en los casos notificados como resultado de infecciones por SARS-CoV-2. Este estudio tiene como objetivo describir los datos clínicos, epidemiológicos y de laboratorio de pacientes ingresados en el Hospital Universitario de la Universidad Federal de Vale do São Francisco con sospecha de SARS por COVID-19 o no especificado. Se trata de un estudio observacional, retrospectivo, transversal, con una muestra de 72 individuos, ingresados entre marzo y julio de 2020. Los datos fueron recolectados de historias clínicas electrónicas. Para el análisis de los datos se calcularon frecuencias simples y relativas y se realizaron pruebas estadísticas mediante el programa SPSS.  La mayoría de los individuos eran hombres y tenían una edad promedio de aproximadamente 57 años. Del total, el 86,11% presentaba al menos una comorbilidad, siendo las más prevalentes la hipertensión arterial, la edad avanzada y los trastornos metabólicos. Entre los 47 pacientes infectados por SARS-CoV-2, entre los síntomas observados se destacó fiebre, disminución de la saturación de O2 y disnea. En relación a las alteraciones de laboratorio, se observó un aumento en los niveles de TGO, dímero D y ferritina, así como una reducción en las tasas de albúmina y hemoglobina. Además, el 74,5% requirió ventilación mecánica y el resultado principal fue la muerte. Los datos descritos pueden ayudar a la práctica clínica, ya que muestran los hallazgos más frecuentes observados en personas con SARS.As Síndromes Respiratórias Agudas Graves (SRAGs) podem ser definidas pela presença de febre, tosse (ou dor de garganta) e dispneia, ou saturação de O2 reduzida. Embora apresentem variadas etiologias, a pandemia de 2020 trouxe um aumento significativo dos casos notificados decorrentes de infecções pelo SARS-CoV-2. O presente estudo teve como objetivo descrever os dados clínicos, epidemiológicos e laboratoriais de pacientes admitidos no Hospital Universitário da Universidade Federal do Vale do São Francisco com suspeita de SRAG decorrente da COVID-19 ou inespecífica. Trata-se de um estudo retrospectivo, observacional transversal, com amostra de 72 indivíduos, admitidos entre março e julho de 2020. Os dados foram coletados a partir de prontuários eletrônicos. Para as análises dos dados foram realizados o cálculo das frequências simples e relativas e os testes estatísticos através do SPSS. A maioria dos indivíduos foi do sexo masculino, sendo a média da idade de aproximadamente 57 anos. Do total, 86,11% apresentaram, ao menos, uma comorbidade, sendo as mais prevalentes a hipertensão, idade avançada e distúrbios metabólicos. Para os 47 pacientes infectados pelo SARS-CoV-2, dentre os sintomas observados, destacaram-se a febre, saturação de O2 reduzida e dispneia. Em relação às alterações laboratoriais, foram observados o aumento dos níveis de TGO, D-dímero e ferritina, e a redução das taxas de albumina e hemoglobina. Outrossim, 74,5% necessitaram de ventilação mecânica, e o desfecho majoritário foi o óbito. Os dados descritos são capazes de auxiliar a prática clínica, pois evidenciam os achados mais frequentes observados em indivíduos com SRAG.Research, Society and Development2021-12-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2369110.33448/rsd-v10i16.23691Research, Society and Development; Vol. 10 No. 16; e412101623691Research, Society and Development; Vol. 10 Núm. 16; e412101623691Research, Society and Development; v. 10 n. 16; e4121016236912525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/23691/21063Copyright (c) 2021 July Martins de Oliveira; Ian Mazzetti Rodrigues Valle; Carine Rosa Naue; Itamar Santos; Ricardo Santana de Lima; Marcos Duarte Guimarãeshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOliveira, July Martins deValle, Ian Mazzetti RodriguesNaue, Carine RosaSantos, ItamarLima, Ricardo Santana deGuimarães, Marcos Duarte2021-12-20T11:03:07Zoai:ojs.pkp.sfu.ca:article/23691Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:28.929547Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region
Perfil clínico, epidemiológico y de laboratorio de pacientes con Síndromes Respiratorios Agudos Graves (SRAG) y COVID-19, ingresados en un Hospital Universitario de la Región del submédio del São Francisco
Perfil clínico, epidemiológico e laboratorial de pacientes portadores de Síndromes Respiratórias Agudas Graves (SRAGs) e COVID-19, admitidos em um Hospital Universitário da região do submédio do São Francisco
title Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region
spellingShingle Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region
Oliveira, July Martins de
COVID-19
Síndrome Respiratória Aguda Grave
Sinais e sintomas.
COVID-19
Síndrome Respiratorio Agudo Grave
Signos y síntomas.
COVID-19
Severe Acute Respiratory Syndrome
Signs and symptoms.
title_short Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region
title_full Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region
title_fullStr Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region
title_full_unstemmed Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region
title_sort Clinical, epidemiological and laboratory profile of patients with Severe Acute Respiratory Syndromes (SARS) and COVID-19, admitted to a University Hospital in the São Francisco sub-middle region
author Oliveira, July Martins de
author_facet Oliveira, July Martins de
Valle, Ian Mazzetti Rodrigues
Naue, Carine Rosa
Santos, Itamar
Lima, Ricardo Santana de
Guimarães, Marcos Duarte
author_role author
author2 Valle, Ian Mazzetti Rodrigues
Naue, Carine Rosa
Santos, Itamar
Lima, Ricardo Santana de
Guimarães, Marcos Duarte
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, July Martins de
Valle, Ian Mazzetti Rodrigues
Naue, Carine Rosa
Santos, Itamar
Lima, Ricardo Santana de
Guimarães, Marcos Duarte
dc.subject.por.fl_str_mv COVID-19
Síndrome Respiratória Aguda Grave
Sinais e sintomas.
COVID-19
Síndrome Respiratorio Agudo Grave
Signos y síntomas.
COVID-19
Severe Acute Respiratory Syndrome
Signs and symptoms.
topic COVID-19
Síndrome Respiratória Aguda Grave
Sinais e sintomas.
COVID-19
Síndrome Respiratorio Agudo Grave
Signos y síntomas.
COVID-19
Severe Acute Respiratory Syndrome
Signs and symptoms.
description Severe Acute Respiratory Syndromes (SARS) can be defined by the presence of fever, cough (or sore throat) and dyspnoea, or reduction in O2 saturation. Although they have many etiologies, during the 2020 pandemic occurred a significant increase in the reported cases resulting from infections by SARS-CoV-2. The present study aims to describe the clinical, epidemiological and laboratory data of patients admitted to the University Hospital of the Federal University of Vale do São Francisco with suspected SARS due to COVID-19 or unspecified. This is a retrospective, observational cross-sectional study, with a sample of 72 individuals, admitted between March and July 2020. Data were collected from electronic medical records. For data analysis, simple and relative frequencies were calculated and statistical analysis were performed using SPSS. Most individuals were male and had an average age of approximately 57 years. Regarding comorbidity 86.11% had at least one. The most prevalent being hypertension, advanced age and metabolic disorders. Fever, reduced O2 saturation and dyspnoea were the most common symptoms among the 47 patients infected with SARS-CoV-2. High levels of TGO, D-dimer and ferritin, as well as a reduction in the rates of albumin and hemoglobin were the most common laboratory alterations. Furthermore, 74.5% required mechanical ventilation, and the major outcome was death. The data described are able to help clinical practice, as they show the most frequent findings observed in individuals with SARS.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/23691
10.33448/rsd-v10i16.23691
url https://rsdjournal.org/index.php/rsd/article/view/23691
identifier_str_mv 10.33448/rsd-v10i16.23691
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/23691/21063
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 16; e412101623691
Research, Society and Development; Vol. 10 Núm. 16; e412101623691
Research, Society and Development; v. 10 n. 16; e412101623691
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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