Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite

Detalhes bibliográficos
Autor(a) principal: Paula, Marcos Vinícius da Silva
Data de Publicação: 2021
Outros Autores: Alves Junior, Severino
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/20528
Resumo: In this investigation, the influence of gamma radiation in a therapeutic dose, such as the dose generally administered (on average) in two cycles of radiotherapy treatment, was evaluated for the chemical characteristics of nanocomposite films formed by polycaprolactone (PCL) with oxide nanoparticles of ZnO (ZnO NPs). The PCL nanocomposite films with ZnO NPs (PCL/ZnO NCs) were obtained via solvent casting method, using chloroform as solvent, with ZnO NPs mass contents in relation to polymer masses equal to: 02%; 0.4%; 0.6%; 0.8% and 1.0%. After this step, the films obtained were exposed to gamma radiation in a dose of 140 Gy in the presence of air and at room temperature. The influence of gamma radiation in a therapeutic dose on the chemical characteristics of nanocomposite films obtained through the solvent casting method, was accessed through absorption spectroscopy in the infrared region. Our results indicate that the chemical structure of PCL is preserved after exposure to gamma radiation at 140 Gy.
id UNIFEI_90bc0a8a7f720fe3facfac6a8ecb1576
oai_identifier_str oai:ojs.pkp.sfu.ca:article/20528
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocompositeEfectos de la radiación gamma en dosis terapéutica sobre las características químicas del nanocompuesto policaprolactona/ZnOEfeitos da radiação gama em dose terapêutica nas características químicas do nanocompósito policaprolactona/ZnORadiação gamaPolicaprolactonaNanopartículas de ZnO.Gamma radiationPolycaprolactoneZnO nanoparticles.Radiación gammaPolicaprolactonaNanopartículas de ZnO.In this investigation, the influence of gamma radiation in a therapeutic dose, such as the dose generally administered (on average) in two cycles of radiotherapy treatment, was evaluated for the chemical characteristics of nanocomposite films formed by polycaprolactone (PCL) with oxide nanoparticles of ZnO (ZnO NPs). The PCL nanocomposite films with ZnO NPs (PCL/ZnO NCs) were obtained via solvent casting method, using chloroform as solvent, with ZnO NPs mass contents in relation to polymer masses equal to: 02%; 0.4%; 0.6%; 0.8% and 1.0%. After this step, the films obtained were exposed to gamma radiation in a dose of 140 Gy in the presence of air and at room temperature. The influence of gamma radiation in a therapeutic dose on the chemical characteristics of nanocomposite films obtained through the solvent casting method, was accessed through absorption spectroscopy in the infrared region. Our results indicate that the chemical structure of PCL is preserved after exposure to gamma radiation at 140 Gy.En esta investigación se evaluó la influencia de la radiación gamma sobre la dosis terapéutica, como la dosis habitualmente utilizada (en promedio) en dos ciclos de tratamiento de radioterapia, sobre las características químicas de películas de nanocompuestos formadas por policaprolactona (PCL) con nanopartículas de óxido de ZnO (NP de ZnO). Las películas de nanocompuestos de PCL con NP de ZnO (PCL / ZnO NC) se obtuvieron mediante el método de fundición por solvente, utilizando cloroformo como solvente, con contenidos de masa de ZnO NP en relación a la masa de polímero igual a: 02%; 0,4%; 0,6%; 0,8% y 1,0%. Tras este paso, las películas obtenidas se expusieron a radiación gamma a una dosis de 140 Gy en presencia de aire y a temperatura ambiente. Se accedió a la influencia de la radiación gamma en dosis terapéutica sobre las características químicas de películas de nanocompuestos obtenidas mediante el método de fundición con solvente, mediante espectroscopía de absorción en la región infrarroja. Nuestros resultados indican que la estructura química del PCL se conserva después de la exposición a radiación gamma a 140 Gy.Nesta investigação, a influencia da radiação gama em dose terapeutica, como por exemplo, a dose costumeiramente utilizada (em media) em dois ciclos de tratamento radioterápico, foi avaliada sobre as características químicas de filmes de nanocompósitos formados pela policaprolactona (PCL) com nanopartículas de óxido de ZnO (ZnO NPs). Os filmes de nancompósitos da PCL com ZnO NPs (PCL/ZnO NCs) foram obtidos através do método de solvent casting, utilizando clorofórmio como solvent, com teores em masa de ZnO NPs em relação a massa do polímero iguais a: 02%; 0.4%; 0.6%; 0.8% e 1.0%. Apos essa etapa os filmes obtidos foram expostos a radiação gama na dose de 140 Gy em presenca de ar e em temperatura ambiente. A influência da radiação gama em dose terapeutica nas caracterísiticas químicas dos filmes de nanocompósitos obtidos através do médoto de solvent casting, foi acessada através da espectroscopia de absorção na região do infravermelho. Nossos resultados indicam que a estrutura química da PCL é preservada após a exposição a radiação gama em 140 Gy.Research, Society and Development2021-09-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2052810.33448/rsd-v10i12.20528Research, Society and Development; Vol. 10 No. 12; e456101220528Research, Society and Development; Vol. 10 Núm. 12; e456101220528Research, Society and Development; v. 10 n. 12; e4561012205282525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/20528/18423Copyright (c) 2021 Marcos Vinícius da Silva Paula; Severino Alves Juniorhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPaula, Marcos Vinícius da Silva Alves Junior, Severino2021-11-14T20:26:51Zoai:ojs.pkp.sfu.ca:article/20528Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:09.316412Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite
Efectos de la radiación gamma en dosis terapéutica sobre las características químicas del nanocompuesto policaprolactona/ZnO
Efeitos da radiação gama em dose terapêutica nas características químicas do nanocompósito policaprolactona/ZnO
title Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite
spellingShingle Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite
Paula, Marcos Vinícius da Silva
Radiação gama
Policaprolactona
Nanopartículas de ZnO.
Gamma radiation
Polycaprolactone
ZnO nanoparticles.
Radiación gamma
Policaprolactona
Nanopartículas de ZnO.
title_short Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite
title_full Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite
title_fullStr Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite
title_full_unstemmed Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite
title_sort Effects of gamma radiation in therapeutic dose on the chemical characteristics of a polycaprolactone/ZnO nanocomposite
author Paula, Marcos Vinícius da Silva
author_facet Paula, Marcos Vinícius da Silva
Alves Junior, Severino
author_role author
author2 Alves Junior, Severino
author2_role author
dc.contributor.author.fl_str_mv Paula, Marcos Vinícius da Silva
Alves Junior, Severino
dc.subject.por.fl_str_mv Radiação gama
Policaprolactona
Nanopartículas de ZnO.
Gamma radiation
Polycaprolactone
ZnO nanoparticles.
Radiación gamma
Policaprolactona
Nanopartículas de ZnO.
topic Radiação gama
Policaprolactona
Nanopartículas de ZnO.
Gamma radiation
Polycaprolactone
ZnO nanoparticles.
Radiación gamma
Policaprolactona
Nanopartículas de ZnO.
description In this investigation, the influence of gamma radiation in a therapeutic dose, such as the dose generally administered (on average) in two cycles of radiotherapy treatment, was evaluated for the chemical characteristics of nanocomposite films formed by polycaprolactone (PCL) with oxide nanoparticles of ZnO (ZnO NPs). The PCL nanocomposite films with ZnO NPs (PCL/ZnO NCs) were obtained via solvent casting method, using chloroform as solvent, with ZnO NPs mass contents in relation to polymer masses equal to: 02%; 0.4%; 0.6%; 0.8% and 1.0%. After this step, the films obtained were exposed to gamma radiation in a dose of 140 Gy in the presence of air and at room temperature. The influence of gamma radiation in a therapeutic dose on the chemical characteristics of nanocomposite films obtained through the solvent casting method, was accessed through absorption spectroscopy in the infrared region. Our results indicate that the chemical structure of PCL is preserved after exposure to gamma radiation at 140 Gy.
publishDate 2021
dc.date.none.fl_str_mv 2021-09-26
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/20528
10.33448/rsd-v10i12.20528
url https://rsdjournal.org/index.php/rsd/article/view/20528
identifier_str_mv 10.33448/rsd-v10i12.20528
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/20528/18423
dc.rights.driver.fl_str_mv Copyright (c) 2021 Marcos Vinícius da Silva Paula; Severino Alves Junior
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Marcos Vinícius da Silva Paula; Severino Alves Junior
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 12; e456101220528
Research, Society and Development; Vol. 10 Núm. 12; e456101220528
Research, Society and Development; v. 10 n. 12; e456101220528
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052690525585408

Registros relacionados