Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report

Detalhes bibliográficos
Autor(a) principal: Freitas, Marcondes Pessoa de
Data de Publicação: 2023
Outros Autores: Silva, Breno Conceição, Gomes, Beatriz Barreto, Santos, Victória Ranna Dias dos, Silva, Milene Costa da, Freitas, Esthefany Dourado de, Ribeiro, Nicolle Santos, Oliveira, Maria Madalena Souza, Gomes Junior, Deusdete Conceição
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/43516
Resumo: Squamous cell carcinoma (SCC) is a malignant epithelial neoplasm derived from keratinocytes, commonly preceded by actinic (solar) keratosis, with unclear etiology but associated with host and environmental factors. The present study aimed to describe the therapeutic association of surgical resection with electrochemotherapy using carboplatin in a case of SCC. The work was conducted using qualitative methodology, providing a detailed case report of a domestic feline treated at a private hospital unit. The cat was of mixed breed, female, spayed, 12 years and 4 months old, with white and gray fur, weighing 5.1 kg. The patient presented with a unilateral ulcerative lesion on the lower right eyelid, which had been evolving for 2 years with a significant increase in size and ulceration for approximately 3 months. After an incisional biopsy for histopathological examination, the diagnosis of SCC was confirmed, and it was decided to perform surgical excision with 2 cm margins, along with two sessions of carboplatin electrochemotherapy. After 40 days from the second electrochemotherapy session, with no signs of recurrence, the patient was discharged.
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spelling Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case reportUso de excisión quirúrgica asociada a electroquimioterapia en el tratamiento de carcinoma de células escamosas en felinos: Reporte de casoUtilização de excisão cirúrgica associada a eletroquimioterapia no tratamento de carcinoma de células escamosas em felino: Relato de casoCCEFelinoEletroquimioterapiaRessecção cirúrgica.CCEFelinoElectroquimioterapiaResección quirúrgica.SCCFelineElectrochemotherapySurgical resection.Squamous cell carcinoma (SCC) is a malignant epithelial neoplasm derived from keratinocytes, commonly preceded by actinic (solar) keratosis, with unclear etiology but associated with host and environmental factors. The present study aimed to describe the therapeutic association of surgical resection with electrochemotherapy using carboplatin in a case of SCC. The work was conducted using qualitative methodology, providing a detailed case report of a domestic feline treated at a private hospital unit. The cat was of mixed breed, female, spayed, 12 years and 4 months old, with white and gray fur, weighing 5.1 kg. The patient presented with a unilateral ulcerative lesion on the lower right eyelid, which had been evolving for 2 years with a significant increase in size and ulceration for approximately 3 months. After an incisional biopsy for histopathological examination, the diagnosis of SCC was confirmed, and it was decided to perform surgical excision with 2 cm margins, along with two sessions of carboplatin electrochemotherapy. After 40 days from the second electrochemotherapy session, with no signs of recurrence, the patient was discharged.El carcinoma de células escamosas (CCE) es una neoplasia epitelial maligna derivada de queratinocitos, comúnmente precedida por queratosis actínica (solar), de etiología no clara pero asociada a factores del hospedador y del ambiente. El presente estudio tuvo como objetivo describir la asociación terapéutica de la resección quirúrgica con electroquimioterapia con carboplatino en un caso de CCE. El trabajo se realizó con una metodología cualitativa, describiendo detalladamente un informe de un caso de un felino doméstico atendido en una unidad hospitalaria privada, de raza no definida (SRD), hembra, castrada, de 12 años y 4 meses, con pelaje blanco y gris, 5,1 Kg de peso, presentando una lesión ulcerativa unilateral en el párpado inferior derecho, con una evolución de 2 años y un aumento significativo de tamaño y ulceración desde hace aproximadamente 3 meses. Después de una biopsia incisional para examen histopatológico se confirmó el diagnóstico de CCE y se optó por la exéresis quirúrgica con márgenes de 2 cm asociada a electroquimioterapia con dos sesiones de carboplatino. Después de 40 días de la segunda sesión de electroquimioterapia, al no haber signos de recidiva, la paciente recibió el alta médica.O carcinoma de células escamosas (CCE) é uma neoplasia epitelial maligna, derivadas de queratinócitos, comumente antecedido por ceratose actínica (solar), de etiologia não clara, mas associada à fatores do hospedeiro e do ambiente. O presente estudo teve por objetivo descrever associação terapêutica da ressecção cirúrgica com eletroquimioterapia com carboplatina em um caso de CCE. O trabalho foi realizado com metodologia qualitativa, descrevendo detalhadamente, um relato de caso de um felino doméstico atendido em uma unidade hospitalar particular, sem raça definida (SRD), fêmea, castrada, 12 anos e 4 meses, pelagem branco e cinza, 5,1 Kg, apresentando lesão ulcerativa unilateral na pálpebra inferior direita, com evolução de 2 anos e aumento expressivo de tamanho e ulceração há aproximadamente 3 meses. Após biópsia incisional para exame histopatológico foi definido o diagnóstico de CCE e optou-se pela excisão cirúrgica com margens de 2cm associada a eletroquimioterapia com duas sessões com carboplatina. Após 40 dias da segunda sessão de eletroquimioterapia, por não haver sinais de recidiva, a paciente recebeu alta médica.Research, Society and Development2023-10-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4351610.33448/rsd-v12i10.43516Research, Society and Development; Vol. 12 No. 10; e85121043516Research, Society and Development; Vol. 12 Núm. 10; e85121043516Research, Society and Development; v. 12 n. 10; e851210435162525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/43516/35000Copyright (c) 2023 Marcondes Pessoa de Freitas; Breno Conceição Silva; Beatriz Barreto Gomes; Victória Ranna Dias dos Santos; Milene Costa da Silva; Esthefany Dourado de Freitas; Nicolle Santos Ribeiro; Maria Madalena Souza Oliveira; Deusdete Conceição Gomes Juniorhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFreitas, Marcondes Pessoa de Silva, Breno Conceição Gomes, Beatriz Barreto Santos, Victória Ranna Dias dos Silva, Milene Costa da Freitas, Esthefany Dourado de Ribeiro, Nicolle Santos Oliveira, Maria Madalena Souza Gomes Junior, Deusdete Conceição 2023-10-20T10:57:42Zoai:ojs.pkp.sfu.ca:article/43516Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-10-20T10:57:42Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report
Uso de excisión quirúrgica asociada a electroquimioterapia en el tratamiento de carcinoma de células escamosas en felinos: Reporte de caso
Utilização de excisão cirúrgica associada a eletroquimioterapia no tratamento de carcinoma de células escamosas em felino: Relato de caso
title Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report
spellingShingle Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report
Freitas, Marcondes Pessoa de
CCE
Felino
Eletroquimioterapia
Ressecção cirúrgica.
CCE
Felino
Electroquimioterapia
Resección quirúrgica.
SCC
Feline
Electrochemotherapy
Surgical resection.
title_short Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report
title_full Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report
title_fullStr Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report
title_full_unstemmed Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report
title_sort Surgical excision combined with electrochemotherapy in the treatment of squamous cell carcinoma in a feline: Case report
author Freitas, Marcondes Pessoa de
author_facet Freitas, Marcondes Pessoa de
Silva, Breno Conceição
Gomes, Beatriz Barreto
Santos, Victória Ranna Dias dos
Silva, Milene Costa da
Freitas, Esthefany Dourado de
Ribeiro, Nicolle Santos
Oliveira, Maria Madalena Souza
Gomes Junior, Deusdete Conceição
author_role author
author2 Silva, Breno Conceição
Gomes, Beatriz Barreto
Santos, Victória Ranna Dias dos
Silva, Milene Costa da
Freitas, Esthefany Dourado de
Ribeiro, Nicolle Santos
Oliveira, Maria Madalena Souza
Gomes Junior, Deusdete Conceição
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas, Marcondes Pessoa de
Silva, Breno Conceição
Gomes, Beatriz Barreto
Santos, Victória Ranna Dias dos
Silva, Milene Costa da
Freitas, Esthefany Dourado de
Ribeiro, Nicolle Santos
Oliveira, Maria Madalena Souza
Gomes Junior, Deusdete Conceição
dc.subject.por.fl_str_mv CCE
Felino
Eletroquimioterapia
Ressecção cirúrgica.
CCE
Felino
Electroquimioterapia
Resección quirúrgica.
SCC
Feline
Electrochemotherapy
Surgical resection.
topic CCE
Felino
Eletroquimioterapia
Ressecção cirúrgica.
CCE
Felino
Electroquimioterapia
Resección quirúrgica.
SCC
Feline
Electrochemotherapy
Surgical resection.
description Squamous cell carcinoma (SCC) is a malignant epithelial neoplasm derived from keratinocytes, commonly preceded by actinic (solar) keratosis, with unclear etiology but associated with host and environmental factors. The present study aimed to describe the therapeutic association of surgical resection with electrochemotherapy using carboplatin in a case of SCC. The work was conducted using qualitative methodology, providing a detailed case report of a domestic feline treated at a private hospital unit. The cat was of mixed breed, female, spayed, 12 years and 4 months old, with white and gray fur, weighing 5.1 kg. The patient presented with a unilateral ulcerative lesion on the lower right eyelid, which had been evolving for 2 years with a significant increase in size and ulceration for approximately 3 months. After an incisional biopsy for histopathological examination, the diagnosis of SCC was confirmed, and it was decided to perform surgical excision with 2 cm margins, along with two sessions of carboplatin electrochemotherapy. After 40 days from the second electrochemotherapy session, with no signs of recurrence, the patient was discharged.
publishDate 2023
dc.date.none.fl_str_mv 2023-10-12
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/43516
10.33448/rsd-v12i10.43516
url https://rsdjournal.org/index.php/rsd/article/view/43516
identifier_str_mv 10.33448/rsd-v12i10.43516
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/43516/35000
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 12 No. 10; e85121043516
Research, Society and Development; Vol. 12 Núm. 10; e85121043516
Research, Society and Development; v. 12 n. 10; e85121043516
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052632182816768

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